Capturing sequence diversity in metagenomes with comprehensive and scalable probe design by Metsky, Hayden C, Siddle, Katherine J, Gladden-Young, Adrianne, Qu, James, Yang, David K, Brehio, Patrick, Goldfarb, Andrew, Piantadosi, Anne, Wohl, Shirlee, Carter, Amber, Lin, Aaron E, Barnes, Kayla G, Tully, Damien C, Corleis, Bjӧrn, Hennigan, Scott, Barbosa-Lima, Giselle, Vieira, Yasmine R, Paul, Lauren M, Tan, Amanda L, Garcia, Kimberly F, Parham, Leda A, Odia, Ikponmwosa, Eromon, Philomena, Folarin, Onikepe A, Goba, Augustine, Simon-Lorière, Etienne, Hensley, Lisa, Balmaseda, Angel, Harris, Eva, Kwon, Douglas S, Allen, Todd M, Runstadler, Jonathan A, Smole, Sandra, Bozza, Fernando A, Souza, Thiago M L, Isern, Sharon, Michael, Scott F, Lorenzana, Ivette, Gehrke, Lee, Bosch, Irene, Ebel, Gregory, Grant, Donald S, Happi, Christian T, Park, Daniel J, Gnirke, Andreas, Sabeti, Pardis C, Matranga, Christian B

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Pediatric and adult H3 K27M-mutant diffuse midline glioma treated with the selective DRD2 antagonist ONC201 by Chi, Andrew S., Tarapore, Rohinton S., Hall, Matthew D., Shonka, Nicole, Gardner, Sharon, Umemura, Yoshie, Sumrall, Ashley, Khatib, Ziad, Mueller, Sabine, Kline, Cassie, Zaky, Wafik, Khatua, Soumen, Weathers, Shiao-Pei, Odia, Yazmin, Niazi, Toba N., Daghistani, Doured, Cherrick, Irene, Korones, David, Karajannis, Matthias A., Kong, Xiao-Tang, Minturn, Jane, Waanders, Angela, Arillaga-Romany, Isabel, Batchelor, Tracy, Wen, Patrick Y., Merdinger, Krystal, Schalop, Lee, Stogniew, Martin, Allen, Joshua E., Oster, Wolfgang, Mehta, Minesh P.

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Biological activity of weekly ONC201 in adult recurrent glioblastoma patients by Arrillaga-Romany, Isabel, Odia, Yazmin, Prabhu, Varun V, Tarapore, Rohinton S, Merdinger, Krystal, Stogniew, Martin, Oster, Wolfgang, Allen, Joshua E, Mehta, Minesh, Batchelor, Tracy T, Wen, Patrick Y

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Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways by Venneti, Sriram, Kawakibi, Abed Rahman, Ji, Sunjong, Waszak, Sebastian Martin, Sweha, Stefan R, Mota, Mateus, Pun, Matthew, Deogharkar, Akash, Chung, Chan, Tarapore, Rohinton S, Ramage, Samuel, Chi, Andrew, Wen, Patrick Y, Arrillaga-Romany, Isabel, Batchelor, Tracy T, Butowski, Nicholas A, Sumrall, Ashley, Shonka, Nicole, Harrison, Rebecca A, de Groot, John, Mehta, Minesh, Hall, Matthew D, Daghistani, Doured, Cloughesy, Timothy F, Ellingson, Benjamin M, Beccaria, Kevin, Varlet, Pascale, Kim, Michelle M, Umemura, Yoshie, Garton, Hugh, Franson, Andrea, Schwartz, Jonathan, Jain, Rajan, Kachman, Maureen, Baum, Heidi, Burant, Charles F, Mottl, Sophie, Cartaxo, Rodrigo T, John, Vishal, Messinger, Dana, Qin, Tingting, Peterson, Erik, Sajjakulnukit, Peter, Ravi, Karthik, Waugh, Alyssa, Walling, Dustin, Ding, Yujie, Xia, Ziyun, Schwendeman, Anna, Hawes, Debra, Yang, Fusheng, Judkins, Alexander R, Wahl, Daniel, Lyssiotis, Costas A, de la Nava, Daniel, Alonso, Marta M, Eze, Augustine, Spitzer, Jasper, Schmidt, Susanne V, Duchatel, Ryan J, Dun, Matthew D, Cain, Jason E, Jiang, Li, Stopka, Sylwia A, Baquer, Gerard, Regan, Michael S, Filbin, Mariella G, Agar, Nathalie Y R, Zhao, Lili, Kumar-Sinha, Chandan, Mody, Rajen, Chinnaiyan, Arul, Pratt, Drew, Kurokawa, Ryo, Yadav, Viveka N, Grill, Jacques, Kline, Cassie, Mueller, Sabine, Resnick, Adam, Nazarian, Javad, Allen, Joshua E, Odia, Yazmin, Gardner, Sharon L, Koschmann, Carl

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Selective DRD2 antagonist and ClpP agonist ONC201 in a recurrent non-midline H3 K27M-mutant glioma cohort by Odia, Yazmin, Hall, Matthew D, Cloughesy, Timothy Francis, Wen, Patrick Y, Arrillaga-Romany, Isabel, Daghistani, Doured, Mehta, Minesh P, Tarapore, Rohinton S, Ramage, Samuel C, Allen, Joshua E

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RTID-08. A PHASE 1/2 STUDY OF SELINEXOR IN COMBINATION WITH STANDARD OF CARE THERAPY FOR NEWLY DIAGNOSED OR RECURRENT GLIOBLASTOMA (ndGBM OR rGBM) by Wen, Patrick, Odia, Yazmin, Mehta, Minesh, Goldlust, Samuel, Tamir, Sharon, Shacham, Sharon, Wang, Hongwei, Sheehan, Heidi, Li, Kai

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The Peripheral Blood Transcriptome Is Correlated With PET Measures of Lung Inflammation During Successful Tuberculosis Treatment by Odia, Trust, Malherbe, Stephanus T, Meier, Stuart, Maasdorp, Elizna, Kleynhans, Léanie, du Plessis, Nelita, Loxton, Andre G, Zak, Daniel E, Thompson, Ethan, Duffy, Fergal J, Kuivaniemi, Helena, Ronacher, Katharina, Winter, Jill, Walzl, Gerhard, Tromp, Gerard

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CTNI-27. SINGLE AGENT ACTIVITY OF ONC201 IN NON-MIDLINE H3 K27M-MUTANT DIFFUSE GLIOMAS by Odia, Yazmin, Sumrall, Ashley, Cloughesy, Timothy, Nghiemphu, Phioanh, Hall, Matthew, Daghistani, Doured, Mehta, Minesh, Lassman, Andrew, Arrillaga-Romany, Isabel, Gardner, Sharon, Tarapore, Rohinton, Lu, Guangrong, Allen, Joshua, Wen, Patrick

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TMET-02. CLINICAL EFFICACY OF ONC201 IN H3K27M-MUTANT DIFFUSE MIDLINE GLIOMAS IS DRIVEN BY DISRUPTION OF INTEGRATED METABOLIC AND EPIGENETIC PATHWAYS by Venneti, Sriram, Kawakibi, Abed Rahman, Ji, Sunjong, Waszak, Sebastian, Sweha, Stefan, Mota, Mateus, Pun, Matthew, Deogharkar, Akash, Chung, Chan, Tarapore, Rohinton, Ramage, Samuel, Wen, Patrick, Arrillaga-Romany, Isabel, Garton, Hugh, Franson, Andrea, Schwartz, Jonathan, Jain, Rajan, Mottl, Sophie, Cartaxo, Rodrigo, John, Vishal, Messinger, Dana, Qin, Tingting, Peterson, Erik, Sajjakulnukit, Peter, Judkins, Alexander, Wahl, Daniel, Lyssiotis, Costas, de la Nava, Daniel, Alonso, Martha, Duchatel, Ryan, Dun, Matthew, Cain, Jason, Jiang, Li, Filbin, Mariella, Zhao, Lili, Kumar-Sinha, Chandan, Mody, Rajen, Chinnaiyan, Arul, Kurokawa, Ryo, Pratt, Drew, Yadav, Viveka, Grill, Jacques, Kline, Cassie, Mueller, Sabine, Resnick, Adam, Nazarian, Javad, Allen, Joshua, Odia, Yazmin, Gardner, Sharon, Koschmann, Carl

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CTNI-17. A PHASE 1 WITH DOSE EXPANSION/PHASE 2 STUDY OF SELINEXOR IN COMBINATION WITH STANDARD OF CARE THERAPY FOR NEWLY DIAGNOSED OR RECURRENT GLIOBLASTOMA by Odia, Yazmin, Wen, Patrick, Mehta, Minesh, Colman, Howard, Dunbar, Erin, Butowski, Nicholas, Harrison, Rebecca, Schulder, Michael, Boockvar, John, Chow, Frances, Kumthekar, Priya, Mason, Warren, Venur, Vyshak, Plotkin, Scott, Lassman, Andrew, Duic, Paul, Tamir, Sharon, Li, Kai, Liu, Yang, Mundy, Gregory, Damestani, Yasaman, Sbar, Eric, Shah, Jatin, Shacham, Sharon, Goldlust, Samuel

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CTNI-61. CLINICAL EFFICACY AND PREDICTIVE BIOMARKERS OF ONC201 IN H3K27M-MUTANT DIFFUSE MIDLINE GLIOMA by Kawakibi, Abed Rahman, Tarapore, Rohinton, Gardner, Sharon, Chi, Andrew, Kurz, Sylvia, Wen, Patrick Y, Arrillaga-Romany, Isabel, Batchelor, Tracy, Butowski, Nicholas, Sumrall, Ashley, Shonka, Nicole, Harrison, Rebecca, DeGroot, John, Mehta, Minesh, Odia, Yazmin, Hall, Matthew, Daghistani, Doured, Cloughesy, Timothy, Ellingson, Benjamin, Kim, Michelle, Umemura, Yoshie, Garton, Hugh, Franson, Andrea, Schwartz, Jonathan, Li, Sunjong, Cartaxo, Rodrigo, Ravi, Karthik, Cantor, Evan, Cummings, Jessica, Paul, Alyssa, Walling, Dustin, Dun, Matthew, Cain, Jason, Li, Jiang, Filbin, Mariella, Zhao, Lili, Kumar-Sinha, Chandan, Mody, Rajen, Chinnaiyan, Arul, Kurokawa, Ryo, Pratt, Drew, Venneti, Sriram, Grill, Jacques, Kline, Cassie, Mueller, Sabine, Resnick, Adam C, Nazarian, Javad, Waszak, Sebastian, Allen, Joshua E, Koschmann, Carl

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ACTR-33. TUMOR TISSUE PENETRATION AND PHARMACODYNAMICS OF ONC201 IN ADULT RECURRENT GLIOBLASTOMA PATIENTS by Arrillaga-Romany, Isabel, Odia, Yazmin, Allen, Joshua, Prabhu, Varun Vijay, Tarapore, Rohinton, Costa, Debora Vendramini, Shah, Neelima, Cukierman, Edna, Oster, Wolfgang, Mehta, Minesh, Wen, Patrick, Batchelor, Tracy

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CTNI-37. EFFICACY OF ONC201 IN PATIENTS WITH ONC201 FOR RECURRENT H3 K27M-MUTANT DIFFUSE MIDLINE GLIOMA by Arrillaga-Romany, Isabel, Kurz, Sylvia, Tarapore, Rohinton S, Sumrall, Ashley, Butowski, Nicholas, Harrison, Rebecca, de Groot, John, Chi, Andrew, Shonka, Nicole, Umemura, Yoshie, Odia, Yazmin, Mehta, Minesh, Nghiemphu, Phioanh, Cloughesy, Timothy, Taylor, Lynne, Graber, Jerome, Kilburn, Lindsay, Dixit, Karan, Lu, Guangrong, Allen, Joshua, Batchelor, Tracy, Lassman, Andrew, Wen, Patrick

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ACTR-34. SINGLE AGENT ONC201 IN PREVIOUSLY-TREATED, PROGRESSIVE ADULT H3 K27M-MUTANT GLIOMA by Arrillaga-Romany, Isabel, Kurz, Sylvia, Sumrall, Ashley, Butowski, Nicholas, Harrison, Rebecca, DeGroot, John, Chi, Andrew, Sulman, Erik, Shonka, Nicole, Umemura, Yoshie, Odia, Yazmin, Mehta, Minesh, Iwamoto, Fabio, Leia Nghiemphu, P, Cloughesy, Timothy, Tarapore, Rohinton, Merdinger, Krystal, Oster, Wolfgang, Allen, Joshua, Batchelor, Tracy, Lassman, Andrew, Wen, Patrick

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HGG-18. CLINICAL EFFICACY OF ONC201 IN THALAMIC H3 K27M-MUTANT GLIOMA by Kawakibi, Abed Rahman, Tarapore, Rohinton S, Gardner, Sharon, Chi, Andrew, Kurz, Sylvia, Wen, Patrick Y, Arrillaga-Romany, Isabel, Batchelor, Tracy T, Butowski, Nicholas A, Sumrall, Ashley, Shonka, Nicole, Harrison, Rebecca, DeGroot, John, Mehta, Minesh, Odia, Yazmin, Hall, Matthew D, Daghistani, Doured, Cloughesy, Timothy F, Ellingson, Benjamin M, Umemura, Yoshie, Schwartz, Jonathan, Yadav, Vivekanand, Cartaxo, Rodrigo, Siada, Ruby, Miklja, Zachary, Bruzek, Amy, Cantor, Evan, Wierzbicki, Kyle, Paul, Alyssa, Wolfe, Ian, Leaoard, Marcia, Garton, Hugh, Mody, Rajen, Robertson, Patricia L, Lu, Guangrong, Merdinger, Krystal, Venneti, Sriram, Oster, Wolfgang, Allen, Joshua E, Koschmann, Carl

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CTNI-17. CLINICAL EFFICACY AND PREDICTIVE BIOMARKERS OF ONC201 IN H3 K27M-MUTANT DIFFUSE MIDLINE GLIOMA by Rahman Kawakibi, Abed, Tarapore, Rohinton S, Gardner, Sharon, Thomas, Chase, Cartaxo, Rodrigo, Yadav, Viveka Nand, Chi, Andrew, Kurz, Sylvia, Wen, Patrick, Arrillaga-Romany, Isabel, Batchelor, Tracy, Butowski, Nicholas, Sumrall, Ashley, Shonka, Nicole, Harrison, Rebecca, de Groot, John, Mehta, Minesh, Odia, Yazmin, Hall, Matthew, Daghistani, Doured, Cloughesy, Timothy, Ellingson, Benjamin, Umemura, Yoshie, Garton, Hugh, Franson, Andrea, Robertson, Patricia, Schwartz, Jonathan, Cantor, Evan, Miklja, Zachary, Mullan, Brendan, Bruzek, Amy, Siada, Ruby, Cummings, Jessica, Paul, Alyssa, Wolfe, Ian, Jiang, Li, Filbin, Mariella, Vats, Pankaj, Kumar-Sinha, Chandan, Mody, Rajen, Chinnaiyan, Arul, Venneti, Sriram, Lu, Guangrong, Mueller, Sabine, Martinez, Daniel, Resnick, Adam, Nazarian, Javad, Waszak, Sebastian, Allen, Joshua, Koschmann, Carl

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ACTR-34. INTEGRATED CLINICAL EXPERIENCE WITH ONC201 IN PREVIOUSLY-TREATED H3 K27M-MUTANT GLIOMA PATIENTS by Chi, Andrew, Arrillaga-Romany, Isabel, Gardner, Sharon, Wen, Patrick, Batchelor, Tracy, Hall, Matthew, Odia, Yazmin, Khatua, Soumen, Zaky, Wafik, McGovern, Susan, Harrison, Rebecca, de Groot, John, Sumrall, Ashley, Shonka, Nicole, Khatib, Zaid, Karajannis, Matthias, Mueller, Sabine, Tarapore, Rohinton, Merdinger, Krystal, Schalop, Lee, Allen, Joshua, Oster, Wolfgang, P Mehta, Minesh

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PDCT-12. CLINICAL EFFICACY OF ONC201 IN THALAMIC H3 K27M-MUTANT GLIOMA by Rahman Kawakibi, Abed, Gardner, Sharon, Chi, Andrew, Kurz, Sylvia, Wen, Patrick, Arrillaga-Romany, Isabel, Batchelor, Tracy, Butowski, Nicholas, Sumrall, Ashley, Shonka, Nicole, Harrison, Rebecca, DeGroot, John, Mehta, Minesh, Odia, Yazmin, Hall, Matthew, Daghistani, Doured, Cloughesy, Timothy, Ellingson, Benjamin, Umemura, Yoshie, Schwartz, Jonathan, Yadav, Vivekanand, Cartaxo, Rodrigo, Miklja, Zachary, Bruzek, Amy, Siada, Ruby, Mullan, Brendan, Stallard, Stefanie, Muruganand, Ashwath, Wierzbicki, Kyle, Paul, Alyssa, Wolfe, Ian, Kumar-Sinha, Chandan, Marini, Bernard, Leonard, Marcia, Garton, Hugh, Mody, Rajen, Robertson, Patricia, Merdinger, Krystal, Tarapore, Rohinton, Oster, Wolfgang, Allen, Joshua, Koschmann, Carl

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SYST-14 CLINICAL EFFICACY OF ONC201 IN RECURRENT H3 K27M-MUTANT DIFFUSE MIDLINE GLIOMA (DMG) PATIENTS by Arrillaga-Romany, Isabel, Kurz, Sylvia, Tarapore, Rohinton, Lu, Guangrong, Sumrall, Ashley, Butowski, Nicholas, Harrison, Rebecca, DeGroot, John, Chi, Andrew, Shonka, Nicole, Umemura, Yoshie, Odia, Yazmin, Mehta, Minesh, Nghiemphu, Phioanh, Cloughesy, Timothy, Taylor, Lynne, Graber, Jerome, Kilburn, Lindsay, Dixit, Karan, Chen, Clark, Gardner, Sharon, Aguilera, Dolly, MacDonald, Tobey, Cluster, Andrew, Mehta, Kathan, Kheradpour, Albert, Melemed, Allen, Allen, Joshua E, Batchelor, Tracey, Lassman, Andrew, Wen, Patrick

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