Nigral overexpression of α‐synuclein in a rat Parkinson’s disease model indicates alterations in the enteric nervous system and the gut microbiome by O’Donovan, Sarah M., Crowley, Erin K., Brown, Jillian R.‐M., O’Sullivan, Orla, O’Leary, Olivia F., Timmons, Suzanne, Nolan, Yvonne M., Clarke, David J., Hyland, Niall P., Joyce, Susan A., Sullivan, Aideen M., O'Neill, Cora

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Alpha-synuclein alters the faecal viromes of rats in a gut-initiated model of Parkinson's disease by Stockdale, Stephen R, Draper, Lorraine A, O'Donovan, Sarah M, Barton, Wiley, O'Sullivan, Orla, Volpicelli-Daley, Laura A, Sullivan, Aideen M, O'Neill, Cora, Hill, Colin

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Discovery and Statistical Genotyping of Copy-Number Variation from Whole-Exome Sequencing Depth by FROMER, Menachem, MORAN, Jennifer L, KIROV, George, SULLIVAN, Patrick F, HULTMAN, Christina M, SKLAR, Pamela, PURCELL, Shaun M, CHAMBERT, Kimberly, BANKS, Eric, BERGEN, Sarah E, RUDERFER, DouglasM, HANDSAKER, Robert E, MCCARROLL, Steven A, O'DONOVAN, Michael C, OWEN, Michael J

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Joint Contributions of Rare Copy Number Variants and Common SNPs to Risk for Schizophrenia by Bergen, Sarah E, Ploner, Alexander, Howrigan, Daniel, O’Donovan, Michael C, Smoller, Jordan W, Sullivan, Patrick F, Sebat, Jonathan, Neale, Benjamin, Kendler, Kenneth S

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De novo mutations in schizophrenia implicate synaptic networks by Fromer, Menachem, Pocklington, Andrew J, Kavanagh, David H, Williams, Hywel J, Dwyer, Sarah, Gormley, Padhraig, Georgieva, Lyudmila, Rees, Elliott, Palta, Priit, Ruderfer, Douglas M, Carrera, Noa, Humphreys, Isla, Johnson, Jessica S, Roussos, Panos, Barker, Douglas D, Banks, Eric, Milanova, Vihra, Grant, Seth G, Hannon, Eilis, Rose, Samuel A, Chambert, Kimberly, Mahajan, Milind, Scolnick, Edward M, Moran, Jennifer L, Kirov, George, Palotie, Aarno, McCarroll, Steven A, Holmans, Peter, Sklar, Pamela, Owen, Michael J, Purcell, Shaun M, O'Donovan, Michael C

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Lack of Support for the Genes by Early Environment Interaction Hypothesis in the Pathogenesis of Schizophrenia by Vassos, Evangelos, Kou, Jiaqi, Tosato, Sarah, Maxwell, Jessye, Dennison, Charlotte A, Legge, Sophie E, Walters, James T R, Owen, Michael J, O’Donovan, Michael C, Breen, Gerome, Lewis, Cathryn M, Sullivan, Patrick F, Hultman, Christina, Ruggeri, Mirella, Walshe, Muriel, Bramon, Elvira, Bergen, Sarah E, Murray, Robin M

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Most genome-wide significant susceptibility loci for schizophrenia and bipolar disorder reported to date cross-traditional diagnostic boundaries by WILLIAMS, Hywel J, CRADDOCK, Nicholas, OWEN, Michael J, O'DONOVAN, Michael C, RUSSO, Giancarlo, HAMSHERE, Marian L, MOSKVINA, Valentina, DWYER, Sarah, SMITH, Rhodri L, GREEN, Elaine, GROZEVA, Detelina, HOLMANS, Peter

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A Population-Based Study of Genetic Variation and Psychotic Experiences in Adolescents by ZAMMIT, Stanley, HAMSHERE, Marian, OWEN, Michael J, O'DONOVAN, Michael C, DWYER, Sarah, GEORGIVA, Lyudmila, TIMPSON, Nic, MOSKVINA, Valentina, RICHARDS, Alexander, EVANS, David M, LEWIS, Glyn, JONES, Peter

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CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1 by Rees, Elliott, Walters, James T R, Chambert, Kimberly D, O'Dushlaine, Colm, Szatkiewicz, Jin, Richards, Alexander L, Georgieva, Lyudmila, Mahoney-Davies, Gerwyn, Legge, Sophie E, Moran, Jennifer L, Genovese, Giulio, Levinson, Douglas, Morris, Derek W, Cormican, Paul, Kendler, Kenneth S, O'Neill, Francis A, Riley, Brien, Gill, Michael, Corvin, Aiden, Sklar, Pamela, Hultman, Christina, Pato, Carlos, Pato, Michele, Sullivan, Patrick F, Gejman, Pablo V, McCarroll, Steven A, O'Donovan, Michael C, Owen, Michael J, Kirov, George

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Transdiagnostic dimensions of psychopathology at first episode psychosis: findings from the multinational EU-GEI study by Quattrone, Diego, Di Forti, Marta, Gayer-Anderson, Charlotte, Ferraro, Laura, Jongsma, Hannah E, Tripoli, Giada, La Cascia, Caterina, La Barbera, Daniele, Tarricone, Ilaria, Berardi, Domenico, Szöke, Andrei, Arango, Celso, Lasalvia, Antonio, Tortelli, Andrea, Llorca, Pierre-Michel, de Haan, Lieuwe, Velthorst, Eva, Bobes, Julio, Bernardo, Miguel, Sanjuán, Julio, Santos, Jose Luis, Arrojo, Manuel, Del-Ben, Cristina Marta, Menezes, Paulo Rossi, Selten, Jean-Paul, Jones, Peter B, Kirkbride, James B, Richards, Alexander L, O'Donovan, Michael C, Sham, Pak C, Vassos, Evangelos, Rutten, Bart PF, van Os, Jim, Morgan, Craig, Lewis, Cathryn M, Murray, Robin M, Reininghaus, Ulrich

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A genomic mutational constraint map using variation in 76,156 human genomes by Chen, Siwei, Francioli, Laurent C, Goodrich, Julia K, Collins, Ryan L, Kanai, Masahiro, Wang, Qingbo, Alföldi, Jessica, Watts, Nicholas A, Vittal, Christopher, Gauthier, Laura D, Poterba, Timothy, Wilson, Michael W, Tarasova, Yekaterina, Phu, William, Grant, Riley, Yohannes, Mary T, Koenig, Zan, Farjoun, Yossi, Banks, Eric, Donnelly, Stacey, Gabriel, Stacey, Gupta, Namrata, Ferriera, Steven, Tolonen, Charlotte, Novod, Sam, Bergelson, Louis, Roazen, David, Ruano-Rubio, Valentin, Covarrubias, Miguel, Llanwarne, Christopher, Petrillo, Nikelle, Wade, Gordon, Jeandet, Thibault, Munshi, Ruchi, Tibbetts, Kathleen, O'Donnell-Luria, Anne, Solomonson, Matthew, Seed, Cotton, Martin, Alicia R, Talkowski, Michael E, Rehm, Heidi L, Daly, Mark J, Tiao, Grace, Neale, Benjamin M, MacArthur, Daniel G, Karczewski, Konrad J

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Demonstration of the utility of DOS-derived fragment libraries for rapid hit derivatisation in a multidirectional fashion by Kidd, Sarah L, Fowler, Elaine, Reinhardt, Till, Compton, Thomas, Mateu, Natalia, Newman, Hector, Bellini, Dom, Talon, Romain, McLoughlin, Joseph, Krojer, Tobias, Aimon, Anthony, Bradley, Anthony, Fairhead, Michael, Brear, Paul, Díaz-Sáez, Laura, McAuley, Katherine, Sore, Hannah F, Madin, Andrew, O'Donovan, Daniel H, Huber, Kilian V. M, Hyvönen, Marko, von Delft, Frank, Dowson, Christopher G, Spring, David R

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Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder by Demontis, Ditte, Walters, Raymond K, Martin, Joanna, Mattheisen, Manuel, Als, Thomas D, Agerbo, Esben, Baldursson, Gisli, Belliveau, Rich, Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Cerrato, Felecia, Chambert, Kimberly, Churchhouse, Claire, Dumont, Ashley, Gandal, Michael, Goldstein, Jacqueline I, Grasby, Katrina L, Grove, Jakob, Gudmundsson, Ólafur O, Hansen, Christine S, Hauberg, Mads Engel, Hollegaard, Mads V, Howrigan, Daniel P, Huang, Hailiang, Jugessur, Astanand, Myhre, Ronny, Stoltenberg, Camilla, Andreassen, Ole Andreas, Asherson, Philip, Burton, Christie L, Boomsma, Dorret I, Cormand, Bru, Dalsgaard, Søren, Haavik, Jan, Sonuga-Barke, Edmund J.S, Sullivan, Patrick F, Thapar, Anita, Tung, Joyce Y, Waldman, Irwin, Medland, Sarah E, Stefansson, Kari, Nordentoft, Merete, Hougaard, David M, Werge, Thomas, Mors, Ole, Mortensen, Preben Bo, Daly, Mark J, Faraone, Stephen V, Børglum, Anders D, Neale, Benjamin M

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Characterization of Single Gene Copy Number Variants in Schizophrenia by Szatkiewicz, Jin P., Fromer, Menachem, Nonneman, Randal J., Ancalade, NaEshia, Johnson, Jessica S., Stahl, Eli A., Rees, Elliott, Bergen, Sarah E., Hultman, Christina M., Kirov, George, O’Donovan, Michael, Owen, Michael, Holmans, Peter, Sklar, Pamela, Sullivan, Patrick F., Purcell, Shaun M., Crowley, James J., Ruderfer, Douglas M.

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Reciprocal Duplication of the Williams-Beuren Syndrome Deletion on Chromosome 7q11.23 Is Associated with Schizophrenia by Mulle, Jennifer Gladys, Pulver, Ann E, McGrath, John A, Wolyniec, Paula S, Dodd, Anne F, Cutler, David J, Sebat, Jonathan, Malhotra, Dheeraj, Nestadt, Gerald, Conrad, Donald F, Hurles, Matthew, Barnes, Chris P, Ikeda, Masashi, Iwata, Nakao, Levinson, Douglas F, Gejman, Pablo V, Sanders, Alan R, Duan, Jubao, Mitchell, Adele A, Peter, Inga, Sklar, Pamela, O’Dushlaine, Colm T, Grozeva, Detelina, O’Donovan, Michael C, Owen, Michael J, Hultman, Christina M, Kähler, Anna K, Sullivan, Patrick F, Kirov, George, Warren, Stephen T

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Trisomy 12 chronic lymphocytic leukemia cells exhibit upregulation of integrin signaling that is modulated by NOTCH1 mutations by Riches, John C., O’Donovan, Conor J., Kingdon, Sarah J., McClanahan, Fabienne, Clear, Andrew J., Neuberg, Donna S., Werner, Lillian, Croce, Carlo M., Ramsay, Alan G., Rassenti, Laura Z., Kipps, Thomas J., Gribben, John G.

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Genome-wide Association Study Identifies Genetic Variation in Neurocan as a Susceptibility Factor for Bipolar Disorder by Cichon, Sven, Mühleisen, Thomas W., Degenhardt, Franziska A., Mattheisen, Manuel, Miró, Xavier, Strohmaier, Jana, Steffens, Michael, Meesters, Christian, Herms, Stefan, Weingarten, Moritz, Priebe, Lutz, Haenisch, Britta, Alexander, Michael, Vollmer, Jennifer, Breuer, René, Schmäl, Christine, Tessmann, Peter, Moebus, Susanne, Wichmann, H.-Erich, Schreiber, Stefan, Müller-Myhsok, Bertram, Lucae, Susanne, Jamain, Stéphane, Leboyer, Marion, Bellivier, Frank, Etain, Bruno, Henry, Chantal, Kahn, Jean-Pierre, Heath, Simon, Hamshere, Marian, O'Donovan, Michael C., Owen, Michael J., Craddock, Nick, Schwarz, Markus, Vedder, Helmut, Kammerer-Ciernioch, Jutta, Reif, Andreas, Sasse, Johanna, Bauer, Michael, Hautzinger, Martin, Wright, Adam, Mitchell, Philip B., Schofield, Peter R., Montgomery, Grant W., Medland, Sarah E., Gordon, Scott D., Martin, Nicholas G., Gustafsson, Omar, Andreassen, Ole, Djurovic, Srdjan, Sigurdsson, Engilbert, Steinberg, Stacy, Stefansson, Hreinn, Stefansson, Kari, Kapur-Pojskic, Lejla, Oruc, Liliana, Rivas, Fabio, Mayoral, Fermín, Chuchalin, Alexander, Babadjanova, Gulja, Tiganov, Alexander S., Pantelejeva, Galina, Abramova, Lilia I., Grigoroiu-Serbanescu, Maria, Diaconu, Carmen C., Czerski, Piotr M., Hauser, Joanna, Zimmer, Andreas, Lathrop, Mark, Schulze, Thomas G., Wienker, Thomas F., Schumacher, Johannes, Maier, Wolfgang, Propping, Peter, Rietschel, Marcella, Nöthen, Markus M.

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High Loading of Polygenic Risk for ADHD in Children With Comorbid Aggression by Hamshere, Marian L., Langley, Kate, Martin, Joanna, Agha, Sharifah Shameem, Stergiakouli, Evangelia, Anney, Richard J.L., Buitelaar, Jan, Faraone, Stephen V., Lesch, Klaus-Peter, Neale, Benjamin M., Franke, Barbara, Sonuga-Barke, Edmund, Asherson, Philip, Merwood, Andrew, Kuntsi, Jonna, Medland, Sarah E., Ripke, Stephan, Steinhausen, Hans-Christoph, Freitag, Christine, Reif, Andreas, Renner, Tobias J., Romanos, Marcel, Romanos, Jasmin, Warnke, Andreas, Meyer, Jobst, Palmason, Haukur, Vasquez, Alejandro Arias, Lambregts-Rommelse, Nanda, Roeyers, Herbert, Biederman, Joseph, Doyle, Alysa E., Hakonarson, Hakon, Rothenberger, Aribert, Banaschewski, Tobias, Oades, Robert D., McGough, James J., Kent, Lindsey, Williams, Nigel, Owen, Michael J., Holmans, Peter, O’Donovan, Michael C., Thapar, Anita

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Widespread genomic influences on phenotype in Dravet syndrome, a ‘monogenic’ condition by Martins Custodio, Helena, Clayton, Lisa M, Bellampalli, Ravishankara, Pagni, Susanna, Silvennoinen, Katri, Caswell, Richard, Brunklaus, Andreas, Guerrini, Renzo, Koeleman, Bobby P C, Lemke, Johannes R, Møller, Rikke S, Scheffer, Ingrid E, Weckhuysen, Sarah, Zara, Federico, Zuberi, Sameer, Kuchenbaecker, Karoline, Balestrini, Simona, Mills, James D, Sisodiya, Sanjay M

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Signatures of TOP1 transcription-associated mutagenesis in cancer and germline by Reijns, Martin A M, Parry, David A, Williams, Thomas C, Nadeu, Ferran, Hindshaw, Rebecca L, Rios Szwed, Diana O, Nicholson, Michael D, Carroll, Paula, Boyle, Shelagh, Royo, Romina, Cornish, Alex J, Xiang, Hang, Ridout, Kate, Schuh, Anna, Aden, Konrad, Palles, Claire, Campo, Elias, Stankovic, Tatjana, Taylor, Martin S, Jackson, Andrew P

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