Genetics of early onset Parkinson’s disease in Finland: exome sequencing and genome-wide association study

by Siitonen, A, Nalls, M.A, Hernández, D, Gibbs, J.R, Ding, J, Ylikotila, P, Edsall, C, Singleton, A, Majamaa, K
Published in Neurobiology of aging

ABCA7 p.G215S as potential protective factor for Alzheimer’s disease

by Sassi, C, Nalls, M.A, Ridge, P.G, Gibbs, R, Ding, J, Lupton, M.K, Troakes, C, Lunnon, K, Al-Sarraj, S, Brown, K.S, Medway, C, Clement, N, Lord, J, Turton, J, Bras, J, Almeida, M.R, Holstege, H, Louwersheimer, E, van der Flier, W, Scheltens, P, Van Swieten, J.C, Santana, I, Oliveira, C, Morgan, K, Powell, J.F, Kauwe, J.S, Cruchaga, C, Goate, A.M, Singleton, A.B, Guerreiro, R, Hardy, J
Published in Neurobiology of aging

Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy

by Lesage, Suzanne, Deramecourt, Vincent, Jacoupy, Maxime, Hassoun, Sidi Mohamed, Pujol, Claire, Maurage, Claude-Alain, Sahbatou, Mourad, Liebau, Stefan, Bilgic, Basar, Emre, Murat, Erginel-Unaltuna, Nihan, Guven, Gamze, Tison, François, Tranchant, Christine, Corvol, Jean-Christophe, Krack, Paul, Hernandez, Dena G., Gibbs, J. Raphael, Hardy, John, Wood, Nicholas W., Durr, Alexandra, Deleuze, Jean-François, Tazir, Meriem, Destée, Alain, Lohmann, Ebba, Corti, Olga, Brice, Alexis, Lesage, Suzanne, Tison, François, Vidailhet, Marie, Corvol, Jean-Christophe, Agid, Yves, Anheim, Mathieu, Bonnet, Anne-Marie, Borg, Michel, Broussolle, Emmanuel, Durif, Franck, Krack, Paul, Klebe, Stephan, Lohmann, Ebba, Vérin, Marc, Viallet, François, Brice, Alexis, Majounie, Elisa, Corvol, Jean Christophe, Ben-Shlomo, Yoav, Berg, Daniela, Bhatia, Kailash, Bochdanovits, Zoltan, Bonin, Michael, Bras, Jose M., Brockmann, Kathrin, Burn, David J., Chen, Honglei, Clarke, Carl E., Cookson, Mark R., Counsell, Carl, van Dijk, Karin D., Dong, Jing, Escott-Price, Valentina, Evans, Jonathan R., Gray, Emma, Guerreiro, Rita, van Hilten, Jacobus J., Hollenbeck, Albert, Holmans, Peter, Hu, Michèle, Hudson, Gavin, Hunt, Sarah E., Kilarski, Laura L., Jansen, Iris E., Langford, Cordelia, Lees, Andrew, Lorenz, Delia, Lubbe, Steven, Lungu, Codrin, Martinez, María, Mätzler, Walter, McNeill, Alisdair, Moorby, Catriona, O’Sullivan, Sean S., Pearson, Justin, Ravina, Bernard, Rivadeneira, Fernando, Ryten, Mina, Schapira, Anthony, Sharma, Manu, Sheerin, Una-Marie, Sidransky, Ellen, Spencer, Chris C.A., Stefánsson, Kári, Strange, Amy, Talbot, Kevin, Trabzuni, Daniah, Uitterlinden, André G., van de Warrenburg, Bart, Williams-Gray, Caroline H., Winder-Rhodes, Sophie, Hardy, John, Wood, Nicholas W.
Published in American journal of human genetics

Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing

by Jansen, Iris E, Ye, Hui, Heetveld, Sasja, Lechler, Marie C, Michels, Helen, Seinstra, Renée I, Lubbe, Steven J, Drouet, Valérie, Lesage, Suzanne, Majounie, Elisa, Gibbs, J Raphael, Nalls, Mike A, Ryten, Mina, Botia, Juan A, Vandrovcova, Jana, Simon-Sanchez, Javier, Castillo-Lizardo, Melissa, Rizzu, Patrizia, Blauwendraat, Cornelis, Chouhan, Amit K, Li, Yarong, Yogi, Puja, Amin, Najaf, van Duijn, Cornelia M, Morris, Huw R, Brice, Alexis, Singleton, Andrew B, David, Della C, Nollen, Ellen A, Jain, Shushant, Shulman, Joshua M, Heutink, Peter
Published in Genome Biology

Excessive burden of lysosomal storage disorder gene variants in Parkinson’s disease

by van Rooij, Jeroen, Uitterlinden, André G, Kraaij, Robert, Heutink, Peter, Nalls, Mike A, Plagnol, Vincent, Sharma, Manu, Saad, Mohamad, Simón-Sánchez, Javier, Schulte, Claudia, Lesage, Suzanne, Arepalli, Sampath, Barker, Roger, Ben, Yoav, Berendse, Henk W, Berg, Daniela, Bhatia, Kailash, de Bie, Rob M A, Bloem, Bas, Bochdanovits, Zoltan, Bonin, Michael, Bras, Jose M, Brockmann, Kathrin, Brooks, Janet, Burn, David J, Majounie, Elisa, Charlesworth, Gavin, Lungu, Codrin, Chen, Honglei, Chong, Sean, Clarke, Carl E, Mark Cooper, J, Corvol, Jean Christophe, Counsell, Carl, Damier, Philippe, Dartigues, Jean-François, Deloukas, Panos, Dexter, David T, van Dijk, Karin D, Durif, Frank, Dürr, Alexandra, Evans, Jonathan R, Foltynie, Thomas, Gardner, Michelle, Raphael Gibbs, J, Gray, Emma, Guerreiro, Rita, Harris, Clare, van Hilten, Jacobus J, Hofman, Albert, Hollenbeck, Albert, Holton, Janice, Hu, Michele, Huang, Xuemei, Wurster, Isabel, Hudson, Gavin, Hunt, Sarah E, Lees, Andrew, Lichtner, Peter, Lopez, Grisel, Lorenz, Delia, McNeill, Alisdair, Moorby, Catriona, Moore, Matthew, Morris, Huw R, Morrison, Karen E, Pearson, Justin, Perlmutter, Joel S, Pétursson, Hjörvar, Pollak, Pierre, Riess, Olaf, Rivadeneira, Fernando, Ryten, Mina, Schapira, Anthony, Scheffer, Hans, Shaw, Karen, Shoulson, Ira, Shulman, Joshua, Sidransky, Ellen, Smith, Colin, Spencer, Chris C A, Stefánsson, Hreinn, Bettella, Francesco, Stockton, Joanna D, Strange, Amy, Talbot, Kevin, Tanner, Carlie M, Tashakkori-Ghanbaria, Avazeh, Trabzuni, Daniah, Uitterlinden, André G, Walker, Robert, van de Warrenburg, Bart, Wickremaratchi, Mirdhu, Williams, Nigel, Williams-Gray, Caroline H, Winder-Rhodes, Sophie, Martinez, Maria, Wood, Nicholas W, Brice, Alexis, Gasser, Thomas
Published in Brain (London, England : 1878)

Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease

by KELLER, Margaux F, SAAD, Mohamad, SCHULTE, Claudia, MOSKVINA, Valentina, DURR, Alexandra, HOLMANS, Peter, KILARSKI, Laura L, GUERREIRO, Rita, HERNANDEZ, Dena G, BRICE, Alexis, YLIKOTILA, Pauli, STEFANSSON, Hreinn, BRAS, Jose, MAJAMAA, Kari, MORRIS, Huw R, WILLIAMS, Nigel, GASSER, Thomas, HEUTINK, Peter, WOOD, Nicholas W, HARDY, John, MARTINEZ, Maria, SINGLETON, Andrew B, NALLS, Michael A, BETTELLA, Francesco, NICOLAOU, Nayia, SIMON-SANCHEZ, Javier, MITTAG, Florian, BÜCHEL, Finja, SHARMA, Manu, RAPHAEL GIBBS, J
Published in Human molecular genetics

Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty

by Cousminer, Diana L, Stergiakouli, Evangelia, Berry, Diane J, Ang, Wei, Groen-Blokhuis, Maria M, Körner, Antje, Siitonen, Niina, Ntalla, Ioanna, Marinelli, Marcella, Perry, John R B, Kettunen, Johannes, Jansen, Rick, Surakka, Ida, Timpson, Nicholas J, Ring, Susan, Mcmahon, George, Power, Chris, Wang, Carol, Kähönen, Mika, Viikari, Jorma, Lehtimäki, Terho, Middeldorp, Christel M, Hulshoff Pol, Hilleke E, Neef, Madlen, Weise, Sebastian, Pahkala, Katja, Niinikoski, Harri, Zeggini, Eleftheria, Panoutsopoulou, Kalliope, Bustamante, Mariona, Penninx, Brenda W J H, Murabito, Joanne, Torrent, Maties, Dedoussis, George V, Kiess, Wieland, Boomsma, Dorret I, Pennell, Craig E, Raitakari, Olli T, Hyppönen, Elina, Davey Smith, George, Ripatti, Samuli, McCarthy, Mark I, Widén, Elisabeth
Published in Human molecular genetics

A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease

by Holmans, Peter, Moskvina, Valentina, Jones, Lesley, Sharma, Manu, Vedernikov, Alexey, Buchel, Finja, Saad, Mohamad, Sadd, Mohamad, Bras, Jose M, Bettella, Francesco, Nicolaou, Nayia, Simón-Sánchez, Javier, Mittag, Florian, Gibbs, J Raphael, Schulte, Claudia, Durr, Alexandra, Guerreiro, Rita, Hernandez, Dena, Brice, Alexis, Stefánsson, Hreinn, Majamaa, Kari, Gasser, Thomas, Heutink, Peter, Wood, Nicholas W, Martinez, Maria, Singleton, Andrew B, Nalls, Michael A, Hardy, John, Morris, Huw R, Williams, Nigel M
Published in Human molecular genetics

Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network

by Chen, Zhao, Tang, Hua, Qayyum, Rehan, Schick, Ursula M, Nalls, Michael A, Handsaker, Robert, Li, Jin, Lu, Yingchang, Yanek, Lisa R, Keating, Brendan, Meng, Yan, van Rooij, Frank J A, Okada, Yukinori, Kubo, Michiaki, Rasmussen-Torvik, Laura, Keller, Margaux F, Lange, Leslie, Evans, Michele, Bottinger, Erwin P, Linderman, Michael D, Ruderfer, Douglas M, Hakonarson, Hakon, Papanicolaou, George, Zonderman, Alan B, Gottesman, Omri, Thomson, Cynthia, Ziv, Elad, Singleton, Andrew B, Loos, Ruth J F, Sleiman, Patrick M A, Ganesh, Santhi, McCarroll, Steven, Becker, Diane M, Wilson, James G, Lettre, Guillaume, Reiner, Alexander P
Published in Human molecular genetics