Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation

by Lombardi, Alyssa A, Gibb, Andrew A, Arif, Ehtesham, Kolmetzky, Devin W, Tomar, Dhanendra, Luongo, Timothy S, Jadiya, Pooja, Murray, Emma K, Lorkiewicz, Pawel K, Hajnóczky, György, Murphy, Elizabeth, Arany, Zoltan P, Kelly, Daniel P, Margulies, Kenneth B, Hill, Bradford G, Elrod, John W
Published in Nature communications

Glutaminolysis is Essential for Myofibroblast Persistence and In Vivo Targeting Reverses Fibrosis and Cardiac Dysfunction in Heart Failure

by Gibb, Andrew A, Murray, Emma K, Huynh, Anh T, Gaspar, Ryan B, Ploesch, Tori L, Bedi, Ken, Lombardi, Alyssa A, Lorkiewicz, Pawel K, Roy, Rajika, Arany, Zolt, Kelly, Daniel P, Margulies, Kenneth B, Hill, Bradford G, Elrod, John W
Published in Circulation (New York, N.Y.)

Cortical bone stem cell-derived exosomes' therapeutic effect on myocardial ischemia-reperfusion and cardiac remodeling

by Schena, Giana J, Murray, Emma K, Hildebrand, Alycia N, Headrick, Alaina L, Yang, Yijun, Koch, Keith A, Kubo, Hajime, Eaton, Deborah, Johnson, Jaslyn, Berretta, Remus, Mohsin, Sadia, Kishore, Raj, McKinsey, Timothy A, Elrod, John W, Houser, Steven R
Published in American journal of physiology. Heart and circulatory physiology

Molecular Signature of HFpEF: Systems Biology in a Cardiac-Centric Large Animal Model

by Gibb, Andrew A, Murray, Emma K, Eaton, Deborah M, Huynh, Anh T, Tomar, Dhanendra, Garbincius, Joanne F, Kolmetzky, Devin W, Berretta, Remus M, Wallner, Markus, Houser, Steven R, Elrod, John W
Published in JACC. Basic to translational science

Abstract 737: N -ethylmaleimide sensitive factor (NSF) is Essential in Necrotic Cell Death

by Murray, Emma K, Lombardi, Alyssa A, Lambert, Jonathan P, Elrod, John W
Published in Circulation research

Abstract 16592: Excessive MCU-Mediated Mitochondrial Calcium Uptake During Chronic Stress Impairs Cardiac Contractility

by Garbincius, Joanne F, Luongo, Timothy S, Lambert, Jonathan P, Mangold, Adam S, Murray, Emma K, Hildebrand, Alycia N, Jadiya, Pooja, Elrod, John W
Published in Circulation (New York, N.Y.)

Abstract 506: Enhanced Mitochondrial Calcium Uptake During Chronic β-adrenergic Stimulation Causes Maladaptive Remodeling and Impaired Left Ventricular Function Independent of Cycl...

by Garbincius, Joanne F, Luongo, Timothy S, Lambert, Jonathan P, Mangold, Adam S, Murray, Emma K, Hildebrand, Alycia N, Jadiya, Pooja, Elrod, John W
Published in Circulation research

Abstract 16406: Epigenetic Regulation of Myofibroblast Differentiation and Persistence is Mediated by Enhanced Glutaminolysis

by Gibb, Andrew A, Murray, Emma K, Huynh, Anh T, Lombardi, Alyssa A, Lorkiewicz, Pawel K, Kolmetzky, Devin W, Lazaropoulos, Michael P, Arany, Zolt P, Kelly, Daniel P, Margulies, Kenneth B, Hill, Bradford G, Elrod, John W
Published in Circulation (New York, N.Y.)

Abstract 16434: Temporal Metabolomic and Transcriptomic Changes in a Large-Animal Model of Hfpef

by Gibb, Andrew A, Murray, Emma K, Eaton, Deborah M, Huynh, Anh T, Tomar, Dhanendra, Garbincius, Joanne F, Kolmetzky, Devin W, Berretta, Remus M, Wallner, Markus, Houser, Steve R, Elrod, John W
Published in Circulation (New York, N.Y.)

Abstract 517: Glutaminolysis is Required to Initiate Myofibroblast Differentiation and Persistence During Stress

by Gibb, Andrew A, Lombardi, Alyssa A, Murray, Emma K, Tan, Yinfei, Lorkiewicz, Pawel K, Huynh, Anh T, Kolmetzky, Devin W, Arany, Zolt, Kelly, Daniel P, Margulies, Kenneth B, Hill, Bradford G, Elrod, John W
Published in Circulation research

Molecular Signature of HFpEF

by Gibb, Andrew A., Murray, Emma K., Eaton, Deborah M., Huynh, Anh T., Tomar, Dhanendra, Garbincius, Joanne F., Kolmetzky, Devin W., Berretta, Remus M., Wallner, Markus, Houser, Steven R., Elrod, John W.
Published in JACC. Basic to translational science

Abstract 14499: N-ethylmaleimide Sensitive Factor (NSF): A New Regulator of Necrotic Cell Death

by Murray, Emma K, Lombardi, Alyssa A, Lambert, Jonathan P, Kolmetzky, Devin, Molkentin, Jeff D, Elrod, John W
Published in Circulation (New York, N.Y.)

Abstract 14480: Enhanced Glutaminolysis Links Metabolism to the Epigenetic Modifications Required for Myofibroblast Differentiation and Persistence During Stress

by Gibb, Andrew A, Murray, Emma K, Lombardi, Alyssa L, Lorkiewicz, Pawel K, Huynh, Anh T, Kolmetzky, Devin W, Arany, Zolt P, Kelly, Daniel P, Margulies, Kenneth B, Hill, Bradford G, Elrod, John W
Published in Circulation (New York, N.Y.)

Past SARS-CoV-2 infection protection against re-infection: a systematic review and meta-analysis

by Stein, Caroline, Nassereldine, Hasan, Sorensen, Reed J D, Amlag, Joanne O, Bisignano, Catherine, Byrne, Sam, Castro, Emma, Coberly, Kaleb, Collins, James K, Dalos, Jeremy, Daoud, Farah, Deen, Amanda, Gakidou, Emmanuela, Giles, John R, Hulland, Erin N, Huntley, Bethany M, Kinzel, Kasey E, Lozano, Rafael, Mokdad, Ali H, Pham, Tom, Pigott, David M, Reiner Jr, Robert C, Vos, Theo, Hay, Simon I, Murray, Christopher J L, Lim, Stephen S
Published in The Lancet (British edition)

Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population

by Bell, Jordana T, Tsai, Pei-Chien, Yang, Tsun-Po, Pidsley, Ruth, Nisbet, James, Glass, Daniel, Mangino, Massimo, Zhai, Guangju, Zhang, Feng, Valdes, Ana, Shin, So-Youn, Dempster, Emma L, Murray, Robin M, Grundberg, Elin, Hedman, Asa K, Nica, Alexandra, Small, Kerrin S, Dermitzakis, Emmanouil T, McCarthy, Mark I, Mill, Jonathan, Spector, Tim D, Deloukas, Panos
Published in PLoS genetics

Transcriptional Signatures of Tau and Amyloid Neuropathology

by Castanho, Isabel, Murray, Tracey K., Hannon, Eilis, Jeffries, Aaron, Walker, Emma, Laing, Emma, Baulf, Hedley, Harvey, Joshua, Bradshaw, Lauren, Randall, Andrew, Moore, Karen, O’Neill, Paul, Lunnon, Katie, Collier, David A., Ahmed, Zeshan, O’Neill, Michael J., Mill, Jonathan
Published in Cell reports (Cambridge)

Longitudinal effects of dog ownership, dog acquisition, and dog loss on children's movement behaviours: findings from the PLAYCE cohort study

by Adams, Emma K, Murray, Kevin, Trost, Stewart G, Christian, Hayley
Published in The international journal of behavioral nutrition and physical activity

Placentation defects are highly prevalent in embryonic lethal mouse mutants

by Perez-Garcia, Vicente, Fineberg, Elena, Wilson, Robert, Murray, Alexander, Mazzeo, Cecilia Icoresi, Tudor, Catherine, Sienerth, Arnold, White, Jacqueline K, Tuck, Elizabeth, Ryder, Edward J, Gleeson, Diane, Siragher, Emma, Wardle-Jones, Hannah, Staudt, Nicole, Wali, Neha, Collins, John, Geyer, Stefan, Busch-Nentwich, Elisabeth M, Galli, Antonella, Smith, James C, Robertson, Elizabeth, Adams, David J, Weninger, Wolfgang J, Mohun, Timothy, Hemberger, Myriam
Published in Nature (London)

Development and internal validation of a novel risk adjustment model for adult patients undergoing emergency laparotomy surgery: the National Emergency Laparotomy Audit risk model

by Eugene, N., Oliver, C.M., Bassett, M.G., Poulton, T.E., Kuryba, A., Johnston, C., Anderson, I.D., Moonesinghe, S.R., Grocott, M.P., Murray, D.M., Cromwell, D.A., Walker, K., Cripps, Martin, Cripps, Paul, Davies, Emma, Drake, Sharon, Galsworthy, Mike, Goodwin, James, Salih, Tom, Lourtie, Jose, Papadimitriou, Dimitri, Peden, Carol
Published in British journal of anaesthesia : BJA

Estimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020–21

by Wang, Haidong, Paulson, Katherine R, Pease, Spencer A, Watson, Stefanie, Comfort, Haley, Zheng, Peng, Aravkin, Aleksandr Y, Bisignano, Catherine, Barber, Ryan M, Alam, Tahiya, Fuller, John E, May, Erin A, Jones, Darwin Phan, Frisch, Meghan E, Abbafati, Cristiana, Adolph, Christopher, Allorant, Adrien, Amlag, Joanne O, Bang-Jensen, Bree, Bertolacci, Gregory J, Bloom, Sabina S, Carter, Austin, Castro, Emma, Chakrabarti, Suman, Chattopadhyay, Jhilik, Cogen, Rebecca M, Collins, James K, Cooperrider, Kimberly, Dai, Xiaochen, Dangel, William James, Daoud, Farah, Dapper, Carolyn, Deen, Amanda, Duncan, Bruce B, Erickson, Megan, Ewald, Samuel B, Fedosseeva, Tatiana, Ferrari, Alize J, Frostad, Joseph Jon, Fullman, Nancy, Gallagher, John, Gamkrelidze, Amiran, Guo, Gaorui, He, Jiawei, Helak, Monika, Henry, Nathaniel J, Hulland, Erin N, Huntley, Bethany M, Kereselidze, Maia, Lazzar-Atwood, Alice, LeGrand, Kate E, Lindstrom, Akiaja, Linebarger, Emily, Lotufo, Paulo A, Lozano, Rafael, Magistro, Beatrice, Malta, Deborah Carvalho, Månsson, Johan, Mantilla Herrera, Ana M, Marinho, Fatima, Mirkuzie, Alemnesh H, Misganaw, Awoke Temesgen, Monasta, Lorenzo, Naik, Paulami, Nomura, Shuhei, O'Brien, Edward G, O'Halloran, James Kevin, Olana, Latera Tesfaye, Ostroff, Samuel M, Penberthy, Louise, Reiner Jr, Robert C, Reinke, Grace, Ribeiro, Antonio Luiz P, Santomauro, Damian Francesco, Schmidt, Maria Inês, Shaw, David H, Sheena, Brittney S, Sholokhov, Aleksei, Skhvitaridze, Natia, Sorensen, Reed J D, Spurlock, Emma Elizabeth, Syailendrawati, Ruri, Topor-Madry, Roman, Troeger, Christopher E, Walcott, Rebecca, Walker, Ally, Wiysonge, Charles Shey, Worku, Nahom Alemseged, Zigler, Bethany, Pigott, David M, Naghavi, Mohsen, Mokdad, Ali H, Lim, Stephen S, Hay, Simon I, Gakidou, Emmanuela, Murray, Christopher J L
Published in The Lancet (British edition)