COVID-19 vaccine development pipeline gears up

by Mullard, Asher
Published in The Lancet

Landmark Alzheimer’s drug approval confounds research community

by Mullard, Asher
Published in Nature (London)

Flooded by the torrent: the COVID-19 drug pipeline

by Mullard, Asher
Published in The Lancet

Drug withdrawal sends critical care specialists back to basics

by Mullard, Asher
Published in The Lancet (British edition)

Budesonide-formoterol reliever therapy versus maintenance budesonide plus terbutaline reliever therapy in adults with mild to moderate asthma (PRACTICAL): a 52-week, open-label, mu...

by Hardy, Jo, Baggott, Christina, Fingleton, James, Reddel, Helen K, Hancox, Robert J, Harwood, Matire, Corin, Andrew, Sparks, Jenny, Hall, Daniela, Sabbagh, Doñah, Mane, Saras, Vohlidkova, Alexandra, Martindale, John, Williams, Mathew, Shirtcliffe, Philippa, Holliday, Mark, Weatherall, Mark, Beasley, Richard, Corin, Andrew, Dronfield, Liz, Helm, Colin, Paterson, Tracy, Poudel, Bhuwan, Dyer, Malcolm, Jasinski, Christine, Sheahan, Davitt, Sheahan, Pamela, Gailer, Nick, Van Zuilen, Jan, Basa, Andy, Devereaux, Christine, Egan, Karin, Haughey, Sneha, Marks, Rodney, Venter, Dirk, Zhang, Hank, Trevithick, Karen, Williams, Mike, Williams, Philippa, Baggott, Christina, Beasley, Richard, Braithwaite, Irene, Eathorne, Alexandra, Ebmeier, Stefan, Fingleton, James, Hall, Daniela, Hardy, Jo, Harwood, Matire, Holliday, Mark, Houghton, Claire, Mane, Saras, Martindale, John, Oldfield, Karen, Pilcher, Janine, Sabbagh, Doñah, Shirtcliffe, Philippa, Snively, Suzanne, Sparks, Jenny, Vohlidkova, Alexandra, Williams, Mathew, Collins, Patrick, Hassan, Summer, Lam, Annika, Lionnet, Claudette, Montgomery, Barney, Smaill, Liz, Moon, Stella, Quinn, Dean, Bayly-McCredie, Elena, Millar-Coote, Chris, Millar-Coote, Dean, Reid, Jim, Samuel, Anna, Burton, Nicola, Mullard, Tina, Tranquilino, Tyronne, Watson, Edward, Bell, Jill, Harris, Rachel, Richmond, John, Smith, Sue, Krivan, Brent, Robertson, Cheryl, Hancox, Robert J, Weatherall, Mark, Glensor, Sue, O'Connor, Dermot, Porrachia, Anne-Christine, Reddel, Helen K
Published in The Lancet (British edition)

Treatment-Resistant Schizophrenia: Treatment Response and Resistance in Psychosis (TRRIP) Working Group Consensus Guidelines on Diagnosis and Terminology

by Howes, Oliver D, McCutcheon, Rob, Agid, Ofer, de Bartolomeis, Andrea, van Beveren, Nico J.M, Birnbaum, Michael L, Bloomfield, Michael A.P, Bressan, Rodrigo A, Buchanan, Robert W, Carpenter, William T, Castle, David J, Citrome, Leslie, Daskalakis, Zafiris J, Davidson, Michael, Drake, Richard J, Dursun, Serdar, Ebdrup, Bjørn H, Elkis, Helio, Falkai, Peter, Fleischacker, W. Wolfgang, Gadelha, Ary, Gaughran, Fiona, Glenthøj, Birte Y, Graff-Guerrero, Ariel, Hallak, Jaime E.C, Honer, William G, Kennedy, James, Kinon, Bruce J, Lawrie, Stephen M, Lee, Jimmy, Leweke, F. Markus, MacCabe, James H, McNabb, Carolyn B, Meltzer, Herbert, Möller, Hans-Jürgen, Nakajima, Shinchiro, Pantelis, Christos, Reis Marques, Tiago, Remington, Gary, Rossell, Susan L, Russell, Bruce R, Siu, Cynthia O, Suzuki, Takefumi, Sommer, Iris E, Taylor, David, Thomas, Neil, Üçok, Alp, Umbricht, Daniel, Walters, James T.R, Kane, John, Correll, Christoph U
Published in The American journal of psychiatry

Multi-antigen-targeted chimeric antigen receptor T cells for cancer therapy

by Han, Xiao, Wang, Yao, Wei, Jianshu, Han, Weidong
Published in Journal of hematology and oncology

Progression analysis versus traditional methods to quantify slowing of disease progression in Alzheimer's disease

by Jönsson, Linus, Ivkovic, Milana, Atri, Alireza, Handels, Ron, Gustavsson, Anders, Hahn-Pedersen, Julie Hviid, León, Teresa, Lilja, Mathias, Gundgaard, Jens, Raket, Lars Lau
Published in Alzheimer's research & therapy

Exploring new uses for existing drugs: innovative mechanisms to fund independent clinical research

by Verbaanderd, Ciska, Rooman, Ilse, Huys, Isabelle
Published in Current controlled trials in cardiovascular medicine

Machine learning–based integration of network features and chemical structure of compounds for SARS‐CoV‐2 drug effect analysis

by Späth, Julian, Wang, Rui‐Sheng, Humphrey, Maeve, Baumbach, Jan, Loscalzo, Joseph
Published in CPT: pharmacometrics and systems pharmacology

Clinical Research on Alzheimer’s Disease: Progress and Perspectives

by Sun, Bin-Lu, Li, Wei-Wei, Zhu, Chi, Jin, Wang-Sheng, Zeng, Fan, Liu, Yu-Hui, Bu, Xian-Le, Zhu, Jie, Yao, Xiu-Qing, Wang, Yan-Jiang
Published in Neuroscience bulletin

Current status and future outlook for patient‐derived cancer models from a rare cancer research perspective

by Kondo, Tadashi
Published in Cancer science

Small-molecule inhibitors, immune checkpoint inhibitors, and more: FDA-approved novel therapeutic drugs for solid tumors from 1991 to 2021

by Wu, Qing, Qian, Wei, Sun, Xiaoli, Jiang, Shaojie
Published in Journal of hematology and oncology

Favipiravir Use in COVID-19: Analysis of Suspected Adverse Drug Events Reported in the WHO Database

by Kaur, Rimple Jeet, Charan, Jaykaran, Dutta, Siddhartha, Sharma, Paras, Bhardwaj, Pankaj, Sharma, Praveen, Lugova, Halyna, Krishnapillai, Ambigga, Islam, Salequl, Haque, Mainul, Misra, Sanjeev
Published in Infection and drug resistance

Hedgehog pathway in sarcoma: from preclinical mechanism to clinical application

by Banaszek, Natalia, Kurpiewska, Dominika, Kozak, Katarzyna, Rutkowski, Piotr, Sobczuk, Paweł
Published in Journal of cancer research and clinical oncology

Vaccines to prevent COVID-19: a protocol for a living systematic review with network meta-analysis including individual patient data (The LIVING VACCINE Project)

by Korang, Steven Kwasi, Juul, Sophie, Nielsen, Emil Eik, Feinberg, Joshua, Siddiqui, Faiza, Ong, Giok, Klingenberg, Sarah, Veroniki, Areti Angeliki, Bu, Fanlong, Thabane, Lehana, Thomsen, Allan Randrup, Jakobsen, Janus C, Gluud, Christian
Published in Systematic reviews

The Risks of miRNA Therapeutics: In a Drug Target Perspective

by Zhang, Song, Cheng, Zhujun, Wang, Yanan, Han, Tianyu
Published in Drug design, development and therapy

Updated report on tools to measure outcomes of clinical trials in fragile X syndrome

by Budimirovic, Dejan B, Berry-Kravis, Elizabeth, Erickson, Craig A, Hall, Scott S, Hessl, David, Reiss, Allan L, King, Margaret K, Abbeduto, Leonard, Kaufmann, Walter E
Published in Journal of neurodevelopmental disorders

Back to the future: targeting the extracellular matrix to treat systemic sclerosis

by Leask, Andrew, Naik, Angha, Stratton, Richard J
Published in Nature reviews. Rheumatology

Measuring what matters to rare disease patients - reflections on the work by the IRDiRC taskforce on patient-centered outcome measures

by Morel, Thomas, Cano, Stefan J
Published in Orphanet journal of rare diseases