Towards prevention of post-traumatic osteoarthritis: report from an international expert working group on considerations for the design and conduct of interventional studies follow...

by Watt, F.E., Corp, N., Kingsbury, S.R., Frobell, R., Englund, M., Felson, D.T., Levesque, M., Majumdar, S., Wilson, C., Beard, D.J., Lohmander, L.S., Kraus, V.B., Roemer, F., Conaghan, P.G., Mason, D.J., Adams, J., Blank, M., Batt, M., Biggs, P., Busse-Morris, M., Button, K., Calder, J., Cook, J., Edwards, C., Fisheleva, E., Hamilton, D.F., Harrison, H., Holt, C., Jones, M., Jones, R., Kluzek, S., Knight, T., Nuki, G., Parekh, S., Peat, G., Pothet, C., Rainer, T., Robinson, N., Sawle, L., Vincent, T., Williams, A., Wise, E., Zhang, W., Bierma-Zeinstra, S.
Published in Osteoarthritis and cartilage

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

by Mercader, Josep M, Udler, Miriam S, Wessel, Jennifer, Teslovich, Tanya M, Caulkins, Lizz, Barajas-Olmos, Francisco, Boerwinkle, Eric, Chen, Ling, Contreras-Cubas, Cecilia, Córdova, Emilio, Correa, Adolfo, DeFronzo, Ralph A, Dolan, Lawrence, Elliott, Amanda, Floyd, James S, Garay-Sevilla, Maria Eugenia, García-Ortiz, Humberto, Heard-Costa, Nancy L, Jørgensen, Marit E, Kang, Hyun Min, Kelsey, Megan, Linneberg, Allan, Liu, Ching-Ti, Liu, Jianjun, Lyssenko, Valeriya, Marcketta, Anthony, Martínez-Hernández, Angélica, Mayer-Davis, Elizabeth, Morrison, Alanna C, Ndungu, Anne, Ng, Maggie C Y, O'Dushlaine, Colm, Post, Wendy S, Vasan, Ramachandran S, Rayner, N William, Revilla-Monsalve, Cristina, Santoro, Nicola, Schurmann, Claudia, Soberón, Xavier, Strom, Tim M, Thameem, Farook, Torres, Jason M, Vujkovic, Marijana, Witte, Daniel R, Atzmon, Gil, Blangero, John, Bonnycastle, Lori L, Chan, Edmund, Cheng, Ching-Yu, Collins, Francis S, de Vries, Paul S, Glaser, Benjamin, Gonzalez, Ma Elena, Groop, Leif, Kooner, Jaspal Singh, Kwak, Soo Heon, Laakso, Markku, Nilsson, Peter, Spector, Timothy D, Tai, E Shyong, Tuomilehto, Jaakko, Wilson, James G, Burke, Brian, Carey, David J, Frossard, Philippe, Hwang, Mi Yeong, Kim, Young Jin, Kirchner, H Lester, Lee, Jong-Young, Lee, Juyoung, Loos, Ruth J F, Ma, Ronald C W, Morris, Andrew D, Palmer, Colin N A, Pankow, James, Rasheed, Asif, Saleheen, Danish, Sim, Xueling, Small, Kerrin S, Teo, Yik Ying, Haiman, Christopher, Hanis, Craig L, Dewey, Frederick E, Baras, Aris, Gieger, Christian, Meitinger, Thomas, Lange, Leslie, Pedersen, Oluf, Zeitler, Philip, Dabelea, Dana, Abecasis, Goncalo, Cox, Nancy J, Sladek, Rob, Meigs, James B, Rotter, Jerome I, Altshuler, David, Burtt, Noël P, Morris, Andrew P, Florez, Jose C, Boehnke, Michael
Published in Nature (London)

Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study

by Forgetta, Vincenzo, Keller-Baruch, Julyan, Forest, Marie, Durand, Audrey, Bhatnagar, Sahir, Kemp, John P, Nethander, Maria, Evans, Daniel, Morris, John A, Kiel, Douglas P, Rivadeneira, Fernando, Johansson, Helena, Harvey, Nicholas C, Mellström, Dan, Karlsson, Magnus, Cooper, Cyrus, Evans, David M, Clarke, Robert, Kanis, John A, Orwoll, Eric, McCloskey, Eugene V, Ohlsson, Claes, Pineau, Joelle, Leslie, William D, Greenwood, Celia M T, Richards, J Brent
Published in PLoS medicine

An obligatory role for neurotensin in high-fat-diet-induced obesity

by Li, Jing, Song, Jun, Zaytseva, Yekaterina Y, Liu, Yajuan, Rychahou, Piotr, Jiang, Kai, Starr, Marlene E, Kim, Ji Tae, Harris, Jennifer W, Yiannikouris, Frederique B, Katz, Wendy S, Nilsson, Peter M, Orho-Melander, Marju, Chen, Jing, Zhu, Haining, Fahrenholz, Timothy, Higashi, Richard M, Gao, Tianyan, Morris, Andrew J, Cassis, Lisa A, Fan, Teresa W-M, Weiss, Heidi L, Dobner, Paul R, Melander, Olle, Jia, Jianhang, Evers, B Mark
Published in Nature (London)

Altered ceramide metabolism is a feature in the extracellular vesicle-mediated spread of alpha-synuclein in Lewy body disorders

by Kurzawa-Akanbi, Marzena, Tammireddy, Seshu, Fabrik, Ivo, Gliaudelytė, Lina, Doherty, Mary K., Heap, Rachel, Matečko-Burmann, Irena, Burmann, Björn M., Trost, Matthias, Lucocq, John M., Gherman, Anda V., Fairfoul, Graham, Singh, Preeti, Burté, Florence, Green, Alison, McKeith, Ian G., Härtlova, Anetta, Whitfield, Phillip D., Morris, Christopher M.
Published in Acta neuropathologica

The β3-adrenergic receptor agonist mirabegron improves glucose homeostasis in obese humans

by Finlin, Brian S, Memetimin, Hasiyet, Zhu, Beibei, Confides, Amy L, Vekaria, Hemendra J, El Khouli, Riham H, Johnson, Zachary R, Westgate, Philip M, Chen, Jianzhong, Morris, Andrew J, Sullivan, Patrick G, Dupont-Versteegden, Esther E, Kern, Philip A
Published in The Journal of clinical investigation

Health indicator recording in UK primary care electronic health records: key implications for handling missing data

by Petersen, Irene, Welch, Catherine A, Nazareth, Irwin, Walters, Kate, Marston, Louise, Morris, Richard W, Carpenter, James R, Morris, Tim P, Pham, Tra My
Published in Clinical epidemiology

Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers

by Deming, Yuetiva, Li, Zeran, Kapoor, Manav, Harari, Oscar, Del-Aguila, Jorge L., Black, Kathleen, Carrell, David, Cai, Yefei, Fernandez, Maria Victoria, Budde, John, Ma, Shengmei, Saef, Benjamin, Howells, Bill, Huang, Kuan-lin, Bertelsen, Sarah, Fagan, Anne M., Holtzman, David M., Morris, John C., Kim, Sungeun, Saykin, Andrew J., De Jager, Philip L., Albert, Marilyn, Moghekar, Abhay, O’Brien, Richard, Riemenschneider, Matthias, Petersen, Ronald C., Blennow, Kaj, Zetterberg, Henrik, Minthon, Lennart, Van Deerlin, Vivianna M., Lee, Virginia Man-Yee, Shaw, Leslie M., Trojanowski, John Q., Schellenberg, Gerard, Haines, Jonathan L., Mayeux, Richard, Pericak-Vance, Margaret A., Farrer, Lindsay A., Peskind, Elaine R., Li, Ge, Di Narzo, Antonio F., Kauwe, John S. K., Goate, Alison M., Cruchaga, Carlos
Published in Acta neuropathologica

Educating health professionals to optimise falls screening in hospitals: protocol for a mixed methods study

by Shaw, L, Kiegaldie, D, Morris, M E
Published in BMC health services research

Clinical Science and Practice in the Age of Large Language Models and Generative Artificial Intelligence

by Schueller, Stephen M., Morris, Robert R.
Published in Journal of consulting and clinical psychology

Aromatase inhibitors versus tamoxifen in early breast cancer: patient-level meta-analysis of the randomised trials

by Anon
Published in The Lancet (British edition)

Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes

by Albrechtsen, A., Grarup, N., Li, Y., Sparsø, T., Cao, H., Jiang, T., Kim, S. Y., Korneliussen, T., Li, Q., Nie, C., Wu, R., Morris, A. P., Ladenvall, C., Cauchi, S., Stančáková, A., Andersen, G., Astrup, A., Banasik, K., Bennett, A. J., Bolund, L., Charpentier, G., Chen, Y., Dekker, J. M., Doney, A. S. F., Dorkhan, M., Forsen, T., Frayling, T. M., Gui, Y., Hallmans, G., Hattersley, A. T., He, K., Hitman, G. A., Holmkvist, J., Huang, S., Jiang, H., Jin, X., Justesen, J. M., Kristiansen, K., Kuusisto, J., Lajer, M., Lantieri, O., Li, W., Liao, Q., Liu, X., Ma, T., Ma, X., Marre, M., Mokrosiński, J., Morris, A. D., Mu, B., Nielsen, A. A., Nijpels, G., Nilsson, P., Palmer, C. N. A., Rayner, N. W., Renström, F., Ribel-Madsen, R., Robertson, N., Rolandsson, O., Rossing, P., Schwartz, T. W., Slagboom, P. E., Sterner, M., Tang, M., Tarnow, L., Tuomi, T., van’t Riet, E., van Leeuwen, N., Varga, T. V., Vestmar, M. A., Walker, M., Wang, B., Wang, Y., Wu, H., Xi, F., Yengo, L., Yu, C., Zhang, J., Zhang, Q., Zhang, W., Zheng, H., Zhou, Y., Altshuler, D., ‘t Hart, L. M., Franks, P. W., Balkau, B., Froguel, P., McCarthy, M. I., Laakso, M., Groop, L., Christensen, C., Brandslund, I., Lauritzen, T., Witte, D. R., Linneberg, A., Jørgensen, T., Hansen, T., Wang, J., Nielsen, R., Pedersen, O.
Published in Diabetologia

Paradoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant

by Palmer, Colin N A, Maglio, Cristina, Pirazzi, Carlo, Burza, Maria Antonella, Adiels, Martin, Burch, Lindsay, Donnelly, Louise A, Colhoun, Helen, Doney, Alexander S, Dillon, John F, Pearson, Ewan R, McCarthy, Mark, Hattersley, Andrew T, Frayling, Tim, Morris, Andrew D, Peltonen, Markku, Svensson, Per-Arne, Jacobson, Peter, Borén, Jan, Sjöström, Lars, Carlsson, Lena M S, Romeo, Stefano
Published in PloS one

A clinical primer for the glymphatic system

by Carlstrom, Lucas P, Eltanahy, Ahmed, Perry, Avital, Rabinstein, Alejandro A, Elder, Benjamin D, Morris, Jonathan M, Meyer, Fredric B, Graffeo, Christopher S, Lundgaard, Iben, Burns, Terry C
Published in Brain (London, England : 1878)

Genetic studies of body mass index yield new insights for obesity biology

by Berndt, Sonja I, Esko, Tonu, Fall, Tove, Gustafsson, Stefan, Workalemahu, Tsegaselassie, Smith, Jennifer A, Absher, Devin, Amin, Najaf, Deng, Guohong, Feitosa, Mary F, Gong, Jian, Pasko, Dorota, Shungin, Dmitry, Strawbridge, Rona J, Zhang, Weihua, Bellis, Claire, Berne, Christian, Böhringer, Stefan, Bonnycastle, Lori L, Boyd, Heather A, Bruinenberg, Marcel, Clarke, Robert, Delgado, Graciela, Folkersen, Lasse, Garcia, Melissa E, Grönberg, Henrik, Gusto, Gaëlle, Hassinen, Maija, Johansson, Åsa, Kinnunen, Leena, Kratzer, Wolfgang, Lichtner, Peter, Lind, Lars, Lorbeer, Roberto, Mahajan, Anubha, Menni, Cristina, Milani, Lili, Musk, Arthur W, Rettig, Rainer, Sanna, Serena, Schumacher, Fredrick R, Shi, Jianxin, Swift, Amy J, Thorand, Barbara, Waterworth, Dawn, Wright, Alan F, Zhang, Qunyuan, Choi, Murim, Dastani, Zari, Gådin, Jesper R, Handsaker, Robert E, Kubo, Michiaki, Salem, Rany M, Tanaka, Toshihiro, Bakker, Stephan J L, Bovet, Pascal, Campbell, Harry, Cesana, Giancarlo, Chakravarti, Aravinda, Chines, Peter S, Crawford, Dana C, den Ruijter, Hester M, Farrall, Martin, Ferrières, Jean, Forrester, Terrence, Hindorff, Lucia A, Humphries, Steve E, Hyppönen, Elina, Jukema, J Wouter, Kovacs, Peter, Kuusisto, Johanna, Männistö, Satu, Morris, Andrew D, Murray, Jeffrey C, Oldehinkel, Albertine J, Rioux, John D, Samani, Nilesh J, Sarzynski, Mark A, Stolk, Ronald P, Völker, Uwe, Waeber, Gérard, Bochud, Murielle, Bottinger, Erwin P, Bouchard, Claude, Froguel, Philippe, Groop, Leif C, Hamsten, Anders, Hui, Jennie, Hunter, David J, Kaplan, Robert C, Schadt, Eric E, van der Harst, Pim, Watkins, Hugh, Weir, David R, Wilson, James F, Heid, Iris M, Stefansson, Kari, Abecasis, Gonçalo R, McCarthy, Mark I, Hirschhorn, Joel N
Published in Nature (London)

Adjuvant bisphosphonate treatment in early breast cancer: meta-analyses of individual patient data from randomised trials

by Coleman, R, Powles, T, Paterson, A, Gnant, M, Anderson, S, Diel, I, Gralow, J, von Minckwitz, G, Moebus, V, Bergh, J, Pritchard, KI, Bliss, J, Cameron, D, Evans, V, Pan, H, Peto, R, Bradley, R, Gray, R, Bartsch, R, Dubsky, P, Fesl, C, Fohler, H, Greil, R, Jakesz, R, Lang, A, Luschin-Ebengreuth, G, Marth, C, Mlineritsch, B, Samonigg, H, Singer, CF, Steger, GG, Stoger, H, Olivotto, I, Ragaz, J, Christiansen, P, Ejlertsen, B, Ewertz, M, Jensen, MB, Moller, S, Mouridsen, HT, Eiermann, W, Hilfrich, J, Jonat, W, Kaufmann, M, Kreienberg, R, Schumacher, M, Blohmer, JU, Costa, SD, Eidtmann, H, Gerber, B, Jackisch, C, Loibl, S, Dafni, U, Markopoulos, C, Blomqvist, C, Saarto, T, Ahn, JH, Jung, KH, Perrone, F, Bass, G, Brown, A, Bryant, J, Costantino, J, Dignam, J, Fisher, B, Geyer, C, Mamounas, EP, Paik, S, Redmond, C, Swain, S, Wickerham, L, Wolmark, N, Perez, E, Ingle, JN, Suman, VJ, Hadji, P, A'Hern, R, Dowsett, M, Makris, A, Parton, M, Pennert, K, Powles, TJ, Smith, IE, Yarnold, JR, Clack, G, Van Poznak, C, Safra, T, Bell, R, Coleman, RE, Dodwell, D, Hinsley, S, Marshall, HC, Solomayer, E, Fehm, T, Lester, J, Winter, MC, Horsman, JM, Aft, R, Brufsky, AM, Llombart, HA
Published in The Lancet (British edition)

An Official American Thoracic Society Clinical Practice Guideline: Diagnosis, Risk Stratification, and Management of Pulmonary Hypertension of Sickle Cell Disease

by KLINGS, Elizabeth S, MACHADO, Roberto F, ROSENZWEIG, Erika B, SOOD, Namita, HSU, Lewis, WILSON, Kevin C, TELEN, Marilyn J, DECASTRO, Laura M, KRISHNAMURTI, Lakshmanan, STEINBERG, Martin H, BADESCH, David B, GLADWIN, Mark T, BARST, Robyn J, MORRIS, Claudia R, MUBARAK, Kamal K, GORDEUK, Victor R, KATO, Gregory J, ATAGA, Kenneth I, GIBBS, J. Simon, CASTRO, Oswaldo
Published in American journal of respiratory and critical care medicine

Long-term outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer: meta-analysis of individual patient data from ten randomised trials

by Asselain, Bernard, Barlow, William, Bergh, Jonas, Bergsten-Nordström, Elizabeth, Bliss, Judith, Boccardo, Francesco, Boddington, Clare, Bogaerts, Jan, Bradley, Rosie, Brain, Etienne, Braybrooke, Jeremy, Broet, Philippe, Bryant, John, Burrett, Julie, Cameron, David, Clarke, Mike, Coates, Alan, Coleman, Robert, Coombes, Raoul Charles, Correa, Candace, Costantino, Joe, Cuzick, Jack, Davidson, Nancy, Davies, Christina, Davies, Lucy, Di Leo, Angelo, Dodwell, David, Dowsett, Mitch, Evans, Vaughan, Ewertz, Marianne, Fisher, Bernard, Forbes, John, Ford, Leslie, Gazet, Jean-Claude, Gelber, Richard, Gettins, Lucy, Gianni, Luca, Gnant, Michael, Godwin, Jon, Goldhirsch, Aron, Goodwin, Pamela, Gray, Richard, Hill, Catherine, Ingle, James, Jagsi, Reshma, Jakesz, Raimund, James, Sam, Janni, Wolfgang, Liu, Hui, Liu, Zulian, Lohrisch, Caroline, Loibl, Sibylle, Mamounas, Eleftherios, Mannu, Gurdeep, Martín, Miguel, Mathoulin, Simone, Mauriac, Louis, McGale, Paul, Morris, Philip, Mukai, Hirofumi, Norton, Larry, Ohashi, Yasuo, Olivotto, Ivo, Paik, Soon, Peto, Richard, Piccart, Martine, Pierce, Lori, Poortmans, Philip, Powles, Trevor, Pritchard, Kathy, Ragaz, Joseph, Raina, Vinod, Ravdin, Peter, Read, Simon, Regan, Meredith, Robertson, John, Rutgers, Emiel, Scholl, Suzy, Slamon, Dennis, Sölkner, Lidija, Steinberg, Seth, Sutcliffe, Rosemary, Swain, Sandra, Taylor, Carolyn, Tutt, Andrew, Valagussa, Pinuccia, van de Velde, Cornelis, van der Hage, Jos, Viale, Giuseppe, von Minckwitz, Gunter, Wang, Yaochen, Wang, Zhe, Wang, Xiang, Whelan, Tim, Wilcken, Nicholas, Winer, Eric, Wolmark, Norman, Wood, William, Zambetti, Milvia, Zujewski, Jo Anne
Published in The lancet oncology

Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 2...

by McGale, P, Taylor, C, Correa, C, Cutter, D, Duane, F, Ewertz, M, Gray, R, Mannu, G, Peto, R, Whelan, T, Wang, Y, Wang, Z, Darby, S
Published in The Lancet (British edition)

Ethnic Differences in the Prevalence of Type 2 Diabetes Diagnoses in the UK: Cross-Sectional Analysis of the Health Improvement Network Primary Care Database

by Pham, Tra My, Carpenter, James R, Morris, Tim P, Sharma, Manuj, Petersen, Irene
Published in Clinical epidemiology