Rare coding variants in ten genes confer substantial risk for schizophrenia

by Poterba, Timothy, Curtis, David, Akil, Huda, Al Eissa, Mariam, Barchas, Jack D, Bigdeli, Tim B, Breen, Gerome, Buckley, Peter F, Bunney, William E, Bybjerg-Grauholm, Jonas, Chapman, Sinéad B, Chen, Wei J, Churchhouse, Claire, Craddock, Nicholas, Cusick, Caroline M, DeLisi, Lynn, Dodge, Sheila, Eskelinen, Saana, Fanous, Ayman H, Faraone, Stephen V, Fiorentino, Alessia, Francioli, Laurent, Gabriel, Stacey B, Gage, Diane, Gagliano Taliun, Sarah A, Ganna, Andrea, Genovese, Giulio, Glahn, David C, Grove, Jakob, Hall, Mei-Hua, Hämäläinen, Eija, Heyne, Henrike O, Holi, Matti, Hougaard, David M, Howrigan, Daniel P, Huang, Hailiang, Kahn, René S, Kang, Hyun Min, Karczewski, Konrad J, Kirov, George, Knowles, James A, Lee, Francis S, Lescai, Francesco, Malaspina, Dolores, Marder, Stephen R, McCarroll, Steven A, Medeiros, Helena, Milani, Lili, Morley, Christopher P, Morris, Derek W, Mortensen, Preben Bo, Myers, Richard M, Nordentoft, Merete, O'Brien, Niamh L, Olivares, Ana Maria, Ongur, Dost, Ouwehand, Willem H, Palmer, Duncan S, Paunio, Tiina, Quested, Digby, Rapaport, Mark H, Rees, Elliott, Rollins, Brandi, Satterstrom, F Kyle, Schatzberg, Alan, Scolnick, Edward, Scott, Laura J, Sharp, Sally I, Sklar, Pamela, Smoller, Jordan W, Sobell, Janet L, Solomonson, Matthew, Stahl, Eli A, Stevens, Christine R, Tiao, Grace, Watson, Stanley J, Watts, Nicholas A, Blackwood, Douglas H, Cohen, Bruce M, Corvin, Aiden P, Esko, Tõnu, Freimer, Nelson B, Glatt, Stephen J, Hultman, Christina M, McQuillin, Andrew, Palotie, Aarno, Pato, Carlos N, Pato, Michele T, Pulver, Ann E, St Clair, David, Tsuang, Ming T, Vawter, Marquis P, Walters, James T, Werge, Thomas M, Ophoff, Roel A, Sullivan, Patrick F, Owen, Michael J, O'Donovan, Michael C, Neale, Benjamin M, Daly, Mark J
Published in Nature (London)

Improved Detection of Common Variants Associated with Schizophrenia by Leveraging Pleiotropy with Cardiovascular-Disease Risk Factors

by Andreassen, Ole A., Djurovic, Srdjan, Thompson, Wesley K., Schork, Andrew J., Kendler, Kenneth S., O’Donovan, Michael C., Rujescu, Dan, Werge, Thomas, van de Bunt, Martijn, Morris, Andrew P., McCarthy, Mark I., Roddey, J. Cooper, McEvoy, Linda K., Desikan, Rahul S., Dale, Anders M.
Published in American journal of human genetics

Biological insights from 108 schizophrenia-associated genetic loci

by Neale, Benjamin M, Pers, Tune H, Agartz, Ingrid, Agerbo, Esben, Amin, Farooq, Bergen, Sarah E, Bigdeli, Tim B, Buckner, Randy L, Cai, Guiqing, Catts, Stanley V, Chan, Raymond C. K, Chen, Eric Y. H, Cheng, Wei, Cheung, Eric F. C, Ann Chong, Siow, Robert Cloninger, C, Cohen, Nadine, Crowley, James J, Davidson, Michael, Davis, Kenneth L, Del Favero, Jurgen, Demontis, Ditte, Dinan, Timothy, Djurovic, Srdjan, Drapeau, Elodie, Eriksson, Johan, Escott-Price, Valentina, Friedl, Marion, Fromer, Menachem, Genovese, Giulio, Georgieva, Lyudmila, Giusti-Rodriguez, Paola, Gopal, Srihari, Gratten, Jacob, Hammer, Christian, Hofman, Andrea, Hougaard, David M, Julia, Antonio, Klovins, Janis, Ausrele Kucinskiene, Zita, Hong Lee, S, Lerer, Bernard, Limborska, Svetlana, Lubinski, Jan, Macek Jr, Milan, Magnusson, Patrik K. E, Mattheisen, Manuel, McDonald, Colm, Michie, Patricia T, Milanova, Vihra, Mokrab, Younes, Muller-Myhsok, Bertram, Nenadic, Igor, Nordin, Annelie, Van Os, Jim, Endophenotypes International Consortium, Psychosis, Parkhomenko, Elena, Pejovic-Milovancevic, Milica, Pimm, Jonathan, Price, Alkes, Purcell, Shaun M, Quested, Digby, Rasmussen, Henrik B, Roffman, Joshua L, Schubert, Christian R, Schwab, Sibylle G, Scott, Rodney J, Seidman, Larry J, Silverman, Jeremy M, Smoller, Jordan W, Steinberg, Stacy, Strengman, Eric, Strohmaier, Jana, Svrakic, Dragan M, Soderman, Erik, Thirumalai, Srinivas, Toncheva, Draga, Tosato, Sarah, Veijola, Juha, Walsh, Dermot, Weiser, Mark, Wolen, Aaron R, Zheng, Xuebin, Wray, Naomi R, Visscher, Peter M, Trust Case-Control Consortium, Wellcome, Andreassen, Ole A, Blackwood, Douglas H. R, Esko, Tonu, Gill, Michael, Jablensky, Assen V, McCarroll, Steven A, Mowry, Bryan J, Owen, Michael J, Pato, Carlos N, Posthuma, Danielle, Rujescu, Dan, Sham, Pak C, Sklar, Pamela, St Clair, David
Published in Nature (London)

A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts

by Ni, Guiyan, Wang, Ying, Ge, Tian, Smoller, Jordan W., Ripke, Stephan, Farh, Kai-How, Holmans, Peter A., Agartz, Ingrid, Belliveau, Richard A., Bigdeli, Tim B., Black, Donald W., Buckner, Randy L., Cheng, Wei, Degenhardt, Franziska, Dudbridge, Frank, Eichhammer, Peter, Farrell, Martilias S., Frank, Josef, Freedman, Robert, Friedl, Marion, Giegling, Ina, Giusti-Rodríguez, Paola, Gratten, Jacob, Hartmann, Annette M., Hollegaard, Mads V., Kahn, René S., Karachanak-Yankova, Sena, Kavanagh, David, Keller, Matthew C., Kennedy, James L., Knowles, James A., Kucinskiene, Zita Ausrele, Li, Tao, Loughland, Carmel M., Lubinski, Jan, Maier, Wolfgang, Mallet, Jacques, Michie, Patricia T., Myin-Germeys, Inez, Nertney, Deborah A., Nicodemus, Kristin K., Nikitina-Zake, Liene, O’Callaghan, Eadbhard, O’Dushlaine, Colm, Pejovic-Milovancevic, Milica, Pocklington, Andrew J., Powell, John, Pulver, Ann E., Ruderfer, Douglas M., Salomaa, Veikko, Shi, Jianxin, Sim, Kang, Slominsky, Petr, Spencer, Chris C.A., Stahl, Eli A., Steinberg, Stacy, Stogmann, Elisabeth, Suvisaari, Jaana, Williams, Nigel M., Witt, Stephanie H., Wormley, Brandon K., Blackwood, Douglas H.R., Bramon, Elvira, Buxbaum, Joseph D., Esko, Tõnu, Gurling, Hugh, Moran, Jennifer L., Mowry, Bryan J., Owen, Michael J., Petryshen, Tracey L., Weinberger, Daniel R., Byrne, Enda M., Abdellaoui, Abdel, Andlauer, Till F.M., Castelao, Enrique, Derks, Eske M., Foo, Jerome C., Forstner, Andreas J., Hall, Lynsey S., Homuth, Georg, Jansen, Rick, Jones, Ian, Jones, Lisa A., Kretzschmar, Warren W., McGuffin, Peter, Mihailov, Evelin, Mostafavi, Sara, Nivard, Michel G., O’Reilly, Paul F., Quiroz, Jorge A., Smith, Daniel J., Thompson, Wesley, Treutlein, Jens, Umbricht, Daniel, Wu, Yang, Zhang, Futao, Grabe, Hans J., Hayward, Caroline, Lewis, Glyn, Wray, Naomi R.
Published in Biological psychiatry (1969)

Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: A report from the Cognitive Genomics consorTium (COGENT)

by Lencz, T, Knowles, Emily, Davies, G, Guha, S, Liewald, DC, Starr, JM, Djurovic, Srdjan, Melle, Ingrid, Sundet, Kjetil Søren, Christoforou, Andrea, Reinvang, Ivar, Mukherjee, Sayan, Derosse, P, Lundervold, Arvid, Steen, Vidar Martin, Espeseth, Thomas, John, M, Räikkönen, K, Widen, E, Palotie, A, Eriksson, JG, Giegling, I, Konte, B, Ikeda, M, Roussos, P, Giakoumaki, S, Burdick, KE, Payton, A, Ollier, W, Horan, M, Donohoe, G, Morris, D, Corvin, A, Gill, M, Pendleton, N, Iwata, N, Darvasi, A, Bitsios, P, Rujescu, D, Lahti, J, Le Hellard, Stephanie, Keller, MC, Andreassen, Ole Andreas, Deary, IJ, Glahn, DC, Malhotra, AK
Published in Molecular psychiatry

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

by Purcell, Shaun M, Wray, Naomi R, Stone, Jennifer L, Visscher, Peter M, O'Donovan, Michael C, Sullivan, Patrick F, Sklar, Pamela
Published in Nature (London)

All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs

by Schork, Andrew J, Thompson, Wesley K, Pham, Phillip, Torkamani, Ali, Roddey, J Cooper, Sullivan, Patrick F, Kelsoe, John R, O'Donovan, Michael C, Furberg, Helena, Schork, Nicholas J, Andreassen, Ole A, Dale, Anders M
Published in PLoS genetics

Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function

by Raychaudhuri, Soumya, Korn, Joshua M, McCarroll, Steven A, Altshuler, David, Sklar, Pamela, Purcell, Shaun, Daly, Mark J
Published in PLoS genetics

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

by Andlauer, Till F M, Guzman-Parra, Jose, Streit, Fabian, Strohmaier, Jana, González, Maria José, Gil Flores, Susana, Cabaleiro Fabeiro, Francisco J, Del Río Noriega, Francisco, Perez, Fermin Perez, Haro González, Jesus, Orozco Diaz, Guillermo, de Diego-Otero, Yolanda, Moreno-Küstner, Berta, Auburger, Georg, Degenhardt, Franziska, Heilmann-Heimbach, Stefanie, Herms, Stefan, Hoffmann, Per, Frank, Josef, Foo, Jerome C, Treutlein, Jens, Witt, Stephanie H, Cichon, Sven, Kogevinas, Manolis, Rivas, Fabio, Mayoral, Fermín, Müller-Myhsok, Bertram, Forstner, Andreas J, Nöthen, Markus M, Rietschel, Marcella
Published in Molecular psychiatry

Genetic Overlap Between Alzheimer's Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes

by Drange, Ole Kristian, Smeland, Olav Bjerkehagen, Shadrin, Alexey A, Finseth, Per Ivar, Witoelar, Aree, Frei, Oleksandr, Wang, Yunpeng, Hassani, Sahar, Djurovic, Srdjan, Dale, Anders M, Andreassen, Ole A
Published in Frontiers in neuroscience

Genetic Schizophrenia Risk Variants Jointly Modulate Total Brain and White Matter Volume

by Terwisscha van Scheltinga, Afke F, Bakker, Steven C, van Haren, Neeltje E.M, Derks, Eske M, Buizer-Voskamp, Jacobine E, Boos, Heleen B.M, Cahn, Wiepke, Hulshoff Pol, Hilleke E, Ripke, Stephan, Ophoff, Roel A, Kahn, René S
Published in Biological psychiatry (1969)

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

by Hultman, Christina M, Vinkhuyzen, Anna A E, Ripke, Stephan, Andreassen, Ole A, Gusev, Alexander, Hu, Xinli, Mantzioris, Vasilis X, McGrath, John J, Mehta, Divya, Stahl, Eli A, Zhao, Qiongyi, Sullivan, Patrick F, Price, Alkes L, O'Donovan, Michael, Okada, Yukinori, Mowry, Bryan J, Wray, Naomi R, Cahn, Wiepke, Cantor, Rita M, Cichon, Sven, Cormican, Paul, Djurovic, Srdjan, Gejman, Pablo V, Georgieva, Lyudmila, Giegling, Ina, Ingason, Andrés, McIntosh, Andrew, McQuillin, Andrew, Nöthen, Markus M, O'Dushlaine, Colm, Olsen, Line, Pato, Carlos N, Pickard, Benjamin S, Posthuma, Danielle, Rasmussen, Henrik B, Rietschel, Marcella, Rujescu, Dan, Silverman, Jeremy M, Thirumalai, Srinivasa, Werge, Thomas, Agartz, Ingrid, Amin, Farooq, Black, Donald W, Buccola, Nancy G, Choudhury, Khalid, Daly, Mark J, Datta, Susmita, Donohoe, Gary J, Dudbridge, Frank, Freimer, Nelson B, Gill, Michael, Gurling, Hugh, De Haan, Lieuwe, Hartmann, Annette M, Holmans, Peter A, Kahn, René S, Keller, Matthew C, Kirov, George K, Krabbendam, Lydia, Krasucki, Robert, Lawrence, Jacob, Lieberman, Jeffrey A, Lin, Dan-Yu, Linszen, Don H, Magnusson, Patrik K E, Mattheisen, Manuel, Mattingsdal, Morten, McCarroll, Steven A, Melle, Ingrid, Milanova, Vihra, Myin-Germeys, Inez, Neale, Benjamin M, Ophoff, Roel A, Pimm, Jonathan, Purcell, Shaun M, Puri, Vinay, Quested, Digby J, Rossin, Lizzy, Ruderfer, Douglas, Sanders, Alan R, Shi, Jianxin, Sklar, Pamela, St Clair, David, Van Os, Jim, Wiersma, Durk, Choi, Hyon K, Coenen, Marieke J H, Dieud, Philippe, Greenberg, Jeffrey D, Huizinga, Tom W J, Padyukov, Leonid, Siminovitch, Katherine A, Tak, Paul P, Worthington, Jane, De Jager, Philip L, Gregersen, Peter K, Klareskog, Lars, Mariette, Xavier, Plenge, Robert M, van Laar, Mart
Published in International journal of epidemiology

Runs of homozygosity implicate autozygosity as a schizophrenia risk factor

by Keller, Matthew C, Simonson, Matthew A, Ripke, Stephan, Neale, Ben M, Gejman, Pablo V, Howrigan, Daniel P, Lee, Sang Hong, Lencz, Todd, Levinson, Douglas F, Sullivan, Patrick F
Published in PLoS genetics

Network-assisted investigation of combined causal signals from genome-wide association studies in schizophrenia

by Jia, Peilin, Wang, Lily, Fanous, Ayman H, Pato, Carlos N, Edwards, Todd L, Zhao, Zhongming
Published in PLoS computational biology

Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis

by Derks, Eske M, Vorstman, Jacob A S, Ripke, Stephan, Kahn, Rene S, Ophoff, Roel A
Published in PloS one

Genetic classification of populations using supervised learning

by Bridges, Michael, Heron, Elizabeth A, O'Dushlaine, Colm, Segurado, Ricardo, Morris, Derek, Corvin, Aiden, Gill, Michael, Pinto, Carlos
Published in PloS one

Two non-synonymous markers in PTPN21 , identified by genome-wide association study data-mining and replication, are associated with schizophrenia

by Chen, Jingchun, Lee, Grace, Fanous, Ayman H, Zhao, Zhongming, Jia, Peilin, O'Neill, Anthony, Walsh, Dermot, Kendler, Kenneth S, Chen, Xiangning, The International Schizophrenia Consortium
Published in Schizophrenia research