Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers

by Blattner, Claudia, Lee, Jeong Hyun, Sliepen, Kwinten, Derking, Ronald, Falkowska, Emilia, de la Peña, Alba Torrents, Cupo, Albert, Julien, Jean-Philippe, van Gils, Marit, Lee, Peter S., Peng, Wenjie, Paulson, James C., Poignard, Pascal, Burton, Dennis R., Moore, John P., Sanders, Rogier W., Wilson, Ian A., Ward, Andrew B.
Published in Immunity (Cambridge, Mass.)

Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies

by Garces, Fernando, Sok, Devin, Kong, Leopold, McBride, Ryan, Kim, Helen J., Saye-Francisco, Karen F., Julien, Jean-Philippe, Hua, Yuanzi, Cupo, Albert, Moore, John P., Paulson, James C., Ward, Andrew B., Burton, Dennis R., Wilson, Ian A.
Published in Cell

Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans

by Garces, Fernando, Lee, Jeong Hyun, de Val, Natalia, Torrents de la Pena, Alba, Kong, Leopold, Puchades, Cristina, Hua, Yuanzi, Stanfield, Robyn L., Burton, Dennis R., Moore, John P., Sanders, Rogier W., Ward, Andrew B., Wilson, Ian A.
Published in Immunity (Cambridge, Mass.)

Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers

by Pritchard, Laura K., Vasiljevic, Snezana, Ozorowski, Gabriel, Seabright, Gemma E., Cupo, Albert, Ringe, Rajesh, Kim, Helen J., Sanders, Rogier W., Doores, Katie J., Burton, Dennis R., Wilson, Ian A., Ward, Andrew B., Moore, John P., Crispin, Max
Published in Cell reports (Cambridge)

PD-L1 Immunohistochemistry Assays for Lung Cancer: Results from Phase 1 of the Blueprint PD-L1 IHC Assay Comparison Project

by Hirsch, Fred R., McElhinny, Abigail, Stanforth, Dave, Ranger-Moore, James, Jansson, Malinka, Kulangara, Karina, Richardson, William, Towne, Penny, Hanks, Debra, Vennapusa, Bharathi, Mistry, Amita, Kalamegham, Rasika, Averbuch, Steve, Novotny, James, Rubin, Eric, Emancipator, Kenneth, McCaffery, Ian, Williams, J. Andrew, Walker, Jill, Longshore, John, Tsao, Ming Sound, Kerr, Keith M.
Published in Journal of thoracic oncology

Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers

by Falkowska, Emilia, Le, Khoa M., Ramos, Alejandra, Doores, Katie J., Lee, Jeong Hyun, Blattner, Claudia, Ramirez, Alejandro, Derking, Ronald, van Gils, Marit J., Liang, Chi-Hui, Mcbride, Ryan, von Bredow, Benjamin, Shivatare, Sachin S., Wu, Chung-Yi, Chan-Hui, Po-Ying, Liu, Yan, Feizi, Ten, Zwick, Michael B., Koff, Wayne C., Seaman, Michael S., Swiderek, Kristine, Moore, John P., Evans, David, Paulson, James C., Wong, Chi-Huey, Ward, Andrew B., Wilson, Ian A., Sanders, Rogier W., Poignard, Pascal, Burton, Dennis R.
Published in Immunity (Cambridge, Mass.)

Altered endosomal-lysosomal biogenesis in melanoma

by Lam, Giang T, Sorvina, Alexandra, Martini, Carmela, Prabhakaran, Sarita, Ung, Ben S-Y, Lazniewska, Joanna, Moore, Courtney R, Beck, Andrew R, Hopkins, Ashley M, Johnson, Ian R D, Caruso, Maria C, Hickey, Shane M, Brooks, Robert D, Jackett, Louise, Karageorgos, Litsa, Foster-Smith, Erwin J, Malone, Victoria, Klebe, Sonja, O'Leary, John J, Brooks, Douglas A, Logan, Jessica M
Published in Neoplasia (New York, N.Y.)

Evaluation of Antisense Oligonucleotides Targeting ATXN3 in SCA3 Mouse Models

by Moore, Lauren R., Rajpal, Gautam, Dillingham, Ian T., Qutob, Maya, Blumenstein, Kate G., Gattis, Danielle, Hung, Gene, Kordasiewicz, Holly B., Paulson, Henry L., McLoughlin, Hayley S.
Published in Molecular therapy. Nucleic acids

Recessive Mutations in SLC38A8 Cause Foveal Hypoplasia and Optic Nerve Misrouting without Albinism

by Poulter, James A., Al-Araimi, Musallam, Conte, Ivan, van Genderen, Maria M., Sheridan, Eamonn, Carr, Ian M., Parry, David A., Shires, Mike, Carrella, Sabrina, Bradbury, John, Khan, Kamron, Lakeman, Phillis, Sergouniotis, Panagiotis I., Webster, Andrew R., Moore, Anthony T., Pal, Bishwanath, Mohamed, Moin D., Venkataramana, Anandula, Ramprasad, Vedam, Shetty, Rohit, Saktivel, Murugan, Kumaramanickavel, Govindasamy, Tan, Alex, Mackey, David A., Hewitt, Alex W., Banfi, Sandro, Ali, Manir, Inglehearn, Chris F., Toomes, Carmel
Published in American journal of human genetics

Defective positioning in granulomas but not lung-homing limits CD4 T-cell interactions with Mycobacterium tuberculosis-infected macrophages in rhesus macaques

by Kauffman, K D, Sallin, M A, Sakai, S, Kamenyeva, O, Kabat, J, Weiner, D, Sutphin, M, Schimel, D, Via, L, Barry, 3rd, C E, Wilder-Kofie, T, Moore, I, Moore, R, Barber, D L
Published in Mucosal immunology

Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein

by Behrens, Anna-Janina, Vasiljevic, Snezana, Pritchard, Laura K., Harvey, David J., Andev, Rajinder S., Krumm, Stefanie A., Struwe, Weston B., Cupo, Albert, Kumar, Abhinav, Zitzmann, Nicole, Seabright, Gemma E., Kramer, Holger B., Spencer, Daniel I.R., Royle, Louise, Lee, Jeong Hyun, Klasse, Per J., Burton, Dennis R., Wilson, Ian A., Ward, Andrew B., Sanders, Rogier W., Moore, John P., Doores, Katie J., Crispin, Max
Published in Cell reports (Cambridge)

COVID-19 vaccine mRNA-1273 elicits a protective immune profile in mice that is not associated with vaccine-enhanced disease upon SARS-CoV-2 challenge

by DiPiazza, Anthony T., Leist, Sarah R., Abiona, Olubukola M., Moliva, Juan I., Werner, Anne, Minai, Mahnaz, Nagata, Bianca M., Bock, Kevin W., Phung, Emily, Schäfer, Alexandra, Dinnon, Kenneth H., Chang, Lauren A., Loomis, Rebecca J., Boyoglu-Barnum, Seyhan, Alvarado, Gabriela S., Sullivan, Nancy J., Edwards, Darin K., Morabito, Kaitlyn M., Mascola, John R., Carfi, Andrea, Corbett, Kizzmekia S., Moore, Ian N., Baric, Ralph S., Graham, Barney S., Ruckwardt, Tracy J.
Published in Immunity (Cambridge, Mass.)

mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits similar B cell expansion, neutralizing responses, and protection from Omicron

by Gagne, Matthew, Moliva, Juan I., Foulds, Kathryn E., Andrew, Shayne F., Flynn, Barbara J., Werner, Anne P., Wagner, Danielle A., Teng, I-Ting, Lin, Bob C., Moore, Christopher, Jean-Baptiste, Nazaire, Carroll, Robin, Foster, Stephanie L., Patel, Mit, Ellis, Madison, Edara, Venkata-Viswanadh, Maldonado, Nahara Vargas, Minai, Mahnaz, McCormick, Lauren, Honeycutt, Christopher Cole, Nagata, Bianca M., Bock, Kevin W., Dulan, Caitlyn N.M., Cordon, Jamilet, Flebbe, Dillon R., Todd, John-Paul M., McCarthy, Elizabeth, Pessaint, Laurent, Van Ry, Alex, Narvaez, Brandon, Valentin, Daniel, Cook, Anthony, Dodson, Alan, Steingrebe, Katelyn, Nurmukhambetova, Saule T., Godbole, Sucheta, Henry, Amy R., Laboune, Farida, Roberts-Torres, Jesmine, Lorang, Cynthia G., Amin, Shivani, Trost, Jessica, Naisan, Mursal, Basappa, Manjula, Willis, Jacquelyn, Wang, Lingshu, Shi, Wei, Doria-Rose, Nicole A., Zhang, Yi, Yang, Eun Sung, Leung, Kwanyee, O’Dell, Sijy, Schmidt, Stephen D., Olia, Adam S., Liu, Cuiping, Harris, Darcy R., Chuang, Gwo-Yu, Stewart-Jones, Guillaume, Renzi, Isabella, Lai, Yen-Ting, Malinowski, Agata, Wu, Kai, Mascola, John R., Carfi, Andrea, Kwong, Peter D., Edwards, Darin K., Lewis, Mark G., Andersen, Hanne, Corbett, Kizzmekia S., Nason, Martha C., McDermott, Adrian B., Suthar, Mehul S., Moore, Ian N., Roederer, Mario, Sullivan, Nancy J., Douek, Daniel C., Seder, Robert A.
Published in Cell

Adaptation and genomic erosion in fragmented Pseudomonas aeruginosa populations in the sinuses of people with cystic fibrosis

by Armbruster, Catherine R., Marshall, Christopher W., Garber, Arkadiy I., Melvin, Jeffrey A., Zemke, Anna C., Moore, John, Zamora, Paula F., Li, Kelvin, Fritz, Ian L., Manko, Christopher D., Weaver, Madison L., Gaston, Jordan R., Morris, Alison, Methé, Barbara, DePas, William H., Lee, Stella E., Cooper, Vaughn S., Bomberger, Jennifer M.
Published in Cell reports (Cambridge)

Genomic Classification of Cutaneous Melanoma

by Aksoy, B. Arman, Amin, Samirkumar B., Bartlett, John, Behera, Madhusmita, Bernard, Brady, Boice, Lori, Brzezinski, Jakub, Cappellini, Giancarlo Antonini, Chevalier, Aaron, Cho, Juok, Cho, Raymond J., Chudamani, Sudha, Clarke, Amanda, Coons, Stephen, Cope, Leslie, Davidsen, Tanja, Davies, Michael A., Delman, Keith A., Dhalla, Noreen, Dubina, Michael, Ebrom, J. Stephen, Eley, Greg, Gao, Jianjiong, Gardner, Johanna, Garraway, Levi A., Gastier-Foster, Julie M., Gaudioso, Carmelo, Getz, Gad, Gomez-Fernandez, Carmen, Hadjipanayis, Angela, Halaban, Ruth, Hayes, D. Neil, Hoadley, Katherine A., Huang, Mei, Jones, Steven J.M., Ju, Zhenlin, Kim, Jaegil, Kirkwood, John M., Krauthammer, Michael, Kwong, Lawrence N., Ladanyi, Marc, Łaźniak, Radoslaw, Lee, Darlene, Liu, Jia, Liu, Wenbin, Long, Georgina V., Ma, Singer, Manikhas, Georgy M., Mann, Graham J., Mayo, Michael, Mehrabi, Sousan, Meng, Shaowu, Meyerson, Matthew, Mieczkowski, Piotr A., Miller, Martin L., Moschos, Stergios, Murawa, Dawid, Ozenberger, Bradley A., Parfitt, Jeremy, Perou, Charles M., Pihl, Todd D., Quinn, Michael J., Radenbaugh, Amie, Ramirez, Nilsa C., Ramirez, Ricardo, Ren, Xiaojia, Reynolds, Sheila M., Robertson, A. Gordon, Roszik, Jason, Saller, Charles, Santoso, Netty, Schein, Jacqueline E., Scolyer, Richard A., Sekhar, Pedamallu Chandra, Shannon, Kerwin F., Sharpless, Norman E., Shelton, Candace, Sheth, Margi, Shi, Yan, Sica, Gabriel L., Sofia, Heidi J., Spillane, Andrew J., Stuart, Joshua, Sun, Yichao, Tam, Angela, Veluvolu, Umadevi, Voronina, Olga, Walter, Vonn, Wan, Yunhu, Watson, Ian R., White, Peter, Wilkerson, Matthew D., Wu, Junyuan, Xu, Andrew Wei, Yang, Da, Yang, Liming, Yang, Lixing, Zhang, Hailei, Zhang, Jianhua, Zmuda, Erik
Published in Cell

TetX Is a Flavin-dependent Monooxygenase Conferring Resistance to Tetracycline Antibiotics

by Yang, Wangrong, Moore, Ian F, Koteva, Kalinka P, Bareich, David C, Hughes, Donald W, Wright, Gerard D
Published in The Journal of biological chemistry

In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies

by Li, Dapeng, Edwards, Robert J., Manne, Kartik, Martinez, David R., Schäfer, Alexandra, Alam, S. Munir, Wiehe, Kevin, Lu, Xiaozhi, Parks, Robert, Sutherland, Laura L., Oguin, Thomas H., McDanal, Charlene, Perez, Lautaro G., Mansouri, Katayoun, Gobeil, Sophie M.C., Janowska, Katarzyna, Stalls, Victoria, Kopp, Megan, Cai, Fangping, Lee, Esther, Foulger, Andrew, Hernandez, Giovanna E., Sanzone, Aja, Tilahun, Kedamawit, Jiang, Chuancang, Tse, Longping V., Bock, Kevin W., Minai, Mahnaz, Nagata, Bianca M., Cronin, Kenneth, Gee-Lai, Victoria, Deyton, Margaret, Barr, Maggie, Von Holle, Tarra, Macintyre, Andrew N., Stover, Erica, Feldman, Jared, Hauser, Blake M., Caradonna, Timothy M., Scobey, Trevor D., Rountree, Wes, Wang, Yunfei, Moody, M. Anthony, Cain, Derek W., DeMarco, C. Todd, Denny, Thomas N., Woods, Christopher W., Petzold, Elizabeth W., Schmidt, Aaron G., Teng, I-Ting, Zhou, Tongqing, Kwong, Peter D., Mascola, John R., Graham, Barney S., Moore, Ian N., Seder, Robert, Andersen, Hanne, Lewis, Mark G., Montefiori, David C., Sempowski, Gregory D., Baric, Ralph S., Acharya, Priyamvada, Haynes, Barton F., Saunders, Kevin O.
Published in Cell

Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer

by Reva, Boris, Chowdhury, Shrabanti, Ji, Jiayi, Whiteaker, Jeffrey R., Colaprico, Antonio, Raman, Pichai, Guo, Yiran, Brown, Miguel A., Ivey, Richard G., Szpyt, John, Guha Thakurta, Sanjukta, Lopez, Gonzalo, Kalayci, Selim, Gümüş, Zeynep H., Yoo, Seungyeul, da Veiga Leprevost, Felipe, Katsnelson, Lizabeth, Wang, Ying, Kennedy, Jacob J., Voytovich, Uliana J., Zhao, Lei, Baubet, Valerie, Tauhid, Lamiya, Lilly, Jena V., Mason, Jennifer L., Farrow, Bailey, Young, Nathan, Leary, Sarah, Moon, Jamie, Petyuk, Vladislav A., Nazarian, Javad, Palmer, James N., Lober, Robert M., Rivero-Hinojosa, Samuel, Wang, Joshua M., Broberg, Matilda, Chu, Rosalie K., Moore, Ronald J., Monroe, Matthew E., Zhao, Rui, Zhu, Jun, Mesri, Mehdi, Boja, Emily, Hiltke, Tara, Rodriguez, Henry, Zhang, Bing, Mani, D.R., Iavarone, Antonio, Schürer, Stephan, Chen, Xi S., Heath, Allison P., Rokita, Jo Lynne, Nesvizhskii, Alexey I., Fenyö, David, Rodland, Karin D., Liu, Tao, Paulovich, Amanda G., Resnick, Adam C., Storm, Phillip B., Rood, Brian R., Wang, Pei, Morgan, Allison M., Waanders, Angela J., Buccoliero, Anna Maria, Leonard, Carina A., Kline, Cassie N., Li, Chunde, Kram, David E., Hanson, Derek, Appert, Elizabeth, Kawaler, Emily A., Raabe, Eric H., Jackson, Eric M., Greenfield, Jeffrey P., Pollack, Ian F., Cain, Jason E., Foster, Jessica B., Palma, July E., Ketchum, Karen A., Blumenberg, Lili, Cornwell, Macintosh, Sarmady, Mahdi, Domagalski, Marcin J., Cieślik, Marcin P., Li, Marilyn M., Wyczalkowski, Matthew A., Connors, Meghan, Gupta, Nalin, Edwards, Nathan J., Vaske, Olena M., Becher, Oren, Firestein, Ron, Mueller, Sabine, Winebrake, Samuel G., Dhanasekaran, Saravana Mohan, Cai, Shuang, Patton, Tatiana, Lorentzen, Travis D., Liu, Wenke, Bocik, William E.
Published in Cell

Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas

by Abeshouse, Adam, Armenia, Joshua, Auman, J. Todd, Bailey, Matthew H., Baker, Laurence, Balasundaram, Miruna, Balu, Saianand, Baylin, Stephen B., Behera, Madhusmita, Benz, Christopher, Bocklage, Thèrése, Boice, Lori, Bootwalla, Moiz S., Bowlby, Reanne, Boyd, Jeff, Castro, Patricia, Cherniack, Andrew D., Chudamani, Sudha, Cooper, Lee A.D., Davis, Ian J., Demetri, George D., Demicco, Elizabeth G., Ding, Li, DiSaia, Phil, Dottino, Peter, Eschbacher, Jennifer, Fedosenko, Konstantin, Ferguson, Martin L., Gao, Qingsong, Gastier-Foster, Julie M., Gerken, Mark, Godwin, Eryn M., Gordienko, Elena, Grilley-Olson, Juneko E., Gutman, David A., Hegde, Apurva M., Heiman, David I., Helsel, Carmen, Hoadley, Katherine A., Hobensack, Shital, Hornick, Jason L., Hoyle, Alan P., Iacocca, Mary, Ittmann, Michael, Jones, Steven J.M., Kim, Jaegil, Ladanyi, Marc, Lai, Phillip H., Larsson, Erik, Lee, Sanghoon, Lehmann, Kjong-Van, Levine, Douglas A., Liu, Jia, Liu, Wenbin, Liu, Eric Minwei, Lu, Yiling, Madan, Rashna, Magliocco, Anthony, Maki, Robert G., Martinez, Cathleen, Mayo, Michael, McLellan, Michael D., Mozgovoy, Evgeny, Mungall, Andrew J., Mungall, Karen, Noble, Michael S., Olvera, Narciso, Paklina, Oxana, Paulauskis, Joseph, Penny, Robert, Perou, Charles M., Perou, Amy H., Pollock, Raphael E., Ramalingam, Suresh S., Reilly, Colleen, Reynolds, Sheila M., Roach, Jeffrey, Roszik, Jason, Sadeghi, Sara, Saksena, Gordon, Sanchez-Vega, Francisco, Sander, Chris, Schein, Jacqueline E., Shelton, Candace, Shelton, Troy, Shi, Yan, Shmulevich, Ilya, Sipahimalani, Payal, Swanson, Patricia, Tarnuzzer, Roy, Thiessen, Nina, Thorne, Leigh B., Van Tine, Brian A., Verhaak, Roel, Voronina, Olga, Wang, Jing, Wise, Lisa, Wyczalkowski, Matthew, Yau, Christina, Yellapantula, Venkata
Published in Cell

Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine

by Goddard, Katrina A.B., Bernhardt, Barbara A., Biswas, Sawona, Bowling, Kevin M., Caga-anan, Charlisse F., Chinnaiyan, Arul M., Clayton, Ellen W., East, Kelly, Garraway, Levi A., Garrett, Jeremy R., Gray, Stacy W., Hindorff, Lucia A., Lewis, Michelle Huckaby, Hutter, Carolyn M., Janne, Pasi A., Knoppers, Bartha M., Krantz, Ian D., Manolio, Teri A., Nickerson, Deborah A., Ou, Jeffrey, Parsons, Donald W., Petersen, Gloria M., Plon, Sharon E., Rehm, Heidi L., Robinson, Dan, Salama, Joseph S., Scollon, Sarah, Shirts, Brian, Tabor, Holly K., Tarczy-Hornoch, Peter, Appelbaum, Paul S., Arora, Shubhangi, Brothers, Kyle B., Brown, Brian L., Caga-anan, Charlisse F., Calikoglu, Muge G., Christensen, Kurt D., Cirino, Allison L., Conlin, Laura K., Crosslin, David R., Davis, James V., Dorschner, Michael O., Dugan, Noreen P., Exe, Nicole, Fishler, Kristen, Ghrundmeier, Bob, Gordon, Adam S., Gray, David E., Gray, Stacy W., Gutierrez, Amanda M., Hensman, Naomi, Hiatt, Susan M., Himes, Patricia, Horike-Pyne, Martha J., Hull, Sara, Jensen, Brian C., Joffe, Steve, Kaufman, Dave, Kim, Jerry H., Klein, William, Lambert, Michele P., Leo, Michael C., Lewis, Katie, Lonigro, Bob, Machini, Kalotina, Manolio, Teri A., McCullough, Laurence, McMullen, Carmit, Mooney, Sean D., Moore, Elizabeth G., Muzny, Donna, Ng, David, Nickerson, Deborah A., Oliver, Nelly M., Parsons, Will, Plon, Sharon, Powell, Bradford C., Raesz-Martinez, Robin A., Raskind, Wendy H., Rehm, Heidi L., Reiss, Jacob A., Robertson, Peggy D., Robinson, Dan, Salama, Joseph, Scarano, Maria I., Sholl, Lynette M., Silverman, Elian, Simmons, Shirley, Spinner, Nancy B., Stoffel, Elena, Tilley, Christian R., Trinidad, Susan, Ubel, Peter, Vassy, Jason L., Vries, Raymond D., Weck, Karen, Wolf, Susan M., Wynn, Julia, Yu, Joon-Ho, Zikmund-Fisher, Brian J.
Published in American journal of human genetics