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Search Results - Merzoug, Farhana F.
Search Results - Merzoug, Farhana F.
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The CDK4/6 Inhibitor Abemaciclib Induces a T Cell Inflamed Tumor Microenvironment and Enhances the Efficacy of PD-L1 Checkpoint Blockade
by
Schaer, David A.
,
Beckmann, Richard P.
,
Dempsey, Jack A.
,
Huber, Lysiane
,
Forest, Amelie
,
Amaladas, Nelusha
,
Li, Yanxia
,
Wang, Ying Cindy
,
Rasmussen, Erik R.
,
Chin, Darin
,
Capen, Andrew
,
Carpenito, Carmine
,
Staschke, Kirk A.
,
Chung, Linda A.
,
Litchfield, Lacey M.
,
Merzoug, Farhana F.
,
Gong, Xueqian
,
Iversen, Philip W.
,
Buchanan, Sean
,
de Dios, Alfonso
,
Novosiadly, Ruslan D.
,
Kalos, Michael
Published in
Cell reports (Cambridge)
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Genomic Aberrations that Activate D-type Cyclins Are Associated with Enhanced Sensitivity to the CDK4 and CDK6 Inhibitor Abemaciclib
by
Gong, Xueqian
,
Litchfield, Lacey M.
,
Webster, Yue
,
Chio, Li-Chun
,
Wong, Swee Seong
,
Stewart, Trent R.
,
Dowless, Michele
,
Dempsey, Jack
,
Zeng, Yi
,
Torres, Raquel
,
Boehnke, Karsten
,
Mur, Cecilia
,
Marugán, Carlos
,
Baquero, Carmen
,
Yu, Chunping
,
Bray, Steven M.
,
Wulur, Isabella H.
,
Bi, Chen
,
Chu, Shaoyou
,
Qian, Hui-Rong
,
Iversen, Philip W.
,
Merzoug, Farhana F.
,
Ye, Xiang S.
,
Reinhard, Christoph
,
De Dios, Alfonso
,
Du, Jian
,
Caldwell, Charles W.
,
Lallena, María José
,
Beckmann, Richard P.
,
Buchanan, Sean G.
Published in
Cancer cell
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Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the RB1 Tumor Suppressor Gene
by
Gong, Xueqian
,
Du, Jian
,
Parsons, Stephen H
,
Merzoug, Farhana F
,
Webster, Yue
,
Iversen, Philip W
,
Chio, Li-Chun
,
Van Horn, Robert D
,
Lin, Xi
,
Blosser, Wayne
,
Han, Bomie
,
Jin, Shaoling
,
Yao, Sufang
,
Bian, Huimin
,
Ficklin, Chris
,
Fan, Li
,
Kapoor, Avnish
,
Antonysamy, Stephen
,
Mc Nulty, Ann M
,
Froning, Karen
,
Manglicmot, Danalyn
,
Pustilnik, Anna
,
Weichert, Kenneth
,
Wasserman, Stephen R
,
Dowless, Michele
,
Marugán, Carlos
,
Baquero, Carmen
,
Lallena, María José
,
Eastman, Scott W
,
Hui, Yu-Hua
,
Dieter, Matthew Z
,
Doman, Thompson
,
Chu, Shaoyou
,
Qian, Hui-Rong
,
Ye, Xiang S
,
Barda, David A
,
Plowman, Gregory D
,
Reinhard, Christoph
,
Campbell, Robert M
,
Henry, James R
,
Buchanan, Sean G
Published in
Cancer discovery
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A Novel Eg5 Inhibitor (LY2523355) Causes Mitotic Arrest and Apoptosis in Cancer Cells and Shows Potent Antitumor Activity in Xenograft Tumor Models
by
Ye, Xiang S
,
Fan, Li
,
Van Horn, Robert D
,
Nakai, Ryuichiro
,
Ohta, Yoshihisa
,
Akinaga, Shiro
,
Murakata, Chikara
,
Yamashita, Yoshinori
,
Yin, Tinggui
,
Credille, Kelly M
,
Donoho, Gregory P
,
Merzoug, Farhana F
,
Li, Heng
,
Aggarwal, Amit
,
Blanchard, Kerry
,
Westin, Eric H
Published in
Molecular cancer therapeutics
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A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib
by
Blosser, Wayne D
,
Dempsey, Jack A
,
McNulty, Ann M
,
Rao, Xi
,
Ebert, Philip J
,
Lowery, Caitlin D
,
Iversen, Philip W
,
Webster, Yue Wang
,
Donoho, Gregory P
,
Gong, Xueqian
,
Merzoug, Farhana F
,
Buchanan, Sean
,
Boehnke, Karsten
,
Yu, Chunping
,
You, Xin Tian
,
Beckmann, Richard P
,
Wu, Wenjuan
,
McNeely, Samuel C
,
Lin, Aimee Bence
,
Martinez, Ricardo
Published in
Oncotarget
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Preclinical analyses and phase I evaluation of LY2603618 administered in combination with Pemetrexed and cisplatin in patients with advanced cancer
by
Calvo, Emiliano
,
Chen, Victor J.
,
Marshall, Mark
,
Ohnmacht, Ute
,
Hynes, Scott M.
,
Kumm, Elizabeth
,
Diaz, H. Bruce
,
Barnard, Darlene
,
Merzoug, Farhana F.
,
Huber, Lysiane
,
Kays, Lisa
,
Iversen, Philip
,
Calles, Antonio
,
Voss, Beatrice
,
Lin, Aimee Bence
,
Dickgreber, Nicolas
,
Wehler, Thomas
,
Sebastian, Martin
Published in
Investigational new drugs
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Combined inhibition of PIM and CDK4/6 suppresses both mTOR signaling and Rb phosphorylation and potentiates PI3K inhibition in cancer cells
by
Litchfield, Lacey M
,
Boehnke, Karsten
,
Brahmachary, Manisha
,
Mur, Cecilia
,
Bi, Chen
,
Stephens, Jennifer R
,
Sauder, J Michael
,
Gutiérrez, Sonia M
,
McNulty, Ann M
,
Ye, Xiang S
,
Wu, Wenjuan
,
Lallena, María José
,
Gong, Xueqian
,
Merzoug, Farhana F
,
Jansen, Valerie M
,
Buchanan, Sean G
Published in
Oncotarget
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Abstract 2535: Enhanced gene expression of replication fork and other E2F targets genes is associated with sensitivity and, paradoxically, also with acquired drug resistance, to th...
by
Blosser, Wayne D.
,
Dempsey, Jack A.
,
McNulty, Ann M.
,
Wu, Wenjuan
,
Ebert, Philip J.
,
Ting, Jason C.
,
Webster, Yue W.
,
Stewart, Trent R.
,
Gong, Xueqian
,
Merzoug, Farhana F.
,
Buchanan, Sean
,
Martinez, Ricardo
Published in
Cancer research (Chicago, Ill.)
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Abstract A12: The CDK4/CDK6 inhibitor abemaciclib inhibits transcriptional targets which facilitate growth in ER+ breast cancer cells
by
McNulty, Ann M.
,
Burke, Teresa
,
Dempsey, Jack A.
,
Marchal, Christophe C.
,
Schade, Andrew E.
,
Szpurka, Hadrian P.
,
Dowless, Michele S.
,
Stephens, Jennifer
,
Edmondson, Denise
,
Stayrook, Keith
,
Caldwell, William C.
,
Buchanan, Sean
,
Merzoug, Farhana F.
,
Beckmann, Richard P.
Published in
Molecular cancer research
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