Deletion of PPARγ in Mesenchymal Lineage Cells Protects Against Aging-Induced Cortical Bone Loss in Mice

by Cao, Jay, Ding, Kehong, Pan, Guodong, Rosario, Raysa, Su, Yun, Bao, Yonggang, Zhou, Hongyan, Xu, Jianru, McGee Lawrence, Meghan E, Hamrick, Mark W, Isales, Carlos M, Shi, Xingming
Published in The journals of gerontology. Series A, Biological sciences and medical sciences

Decreased pericellular matrix production and selection for enhanced cell membrane repair may impair osteocyte responses to mechanical loading in the aging skeleton

by Hagan, Mackenzie L., Yu, Kanglun, Zhu, Jiali, Vinson, Brooke N., Roberts, Rachel L., Montesinos Cartagena, Marlian, Johnson, Maribeth H., Wang, Liyun, Isales, Carlos M., Hamrick, Mark W., McNeil, Paul L., McGee‐Lawrence, Meghan E.
Published in Aging cell

Scapula fracture incidence in reverse total shoulder arthroplasty using screws above or below metaglene central cage: clinical and biomechanical outcomes

by Kennon, Justin C., MD, Lu, Caroline, BS, McGee-Lawrence, Meghan E., PhD, Crosby, Lynn A., MD
Published in Journal of shoulder and elbow surgery

Suberoylanilide hydroxamic acid (SAHA; vorinostat) causes bone loss by inhibiting immature osteoblasts

by McGee-Lawrence, Meghan E, McCleary-Wheeler, Angela L, Secreto, Frank J, Razidlo, David F, Zhang, Minzhi, Stensgard, Bridget A, Li, Xiaodong, Stein, Gary S, Lian, Jane B, Westendorf, Jennifer J
Published in Bone (New York, N.Y.)

Black bear parathyroid hormone has greater anabolic effects on trabecular bone in dystrophin-deficient mice than in wild type mice

by Gray, Sarah K, McGee-Lawrence, Meghan E, Sanders, Jennifer L, Condon, Keith W, Tsai, Chung-Jui, Donahue, Seth W
Published in Bone (New York, N.Y.)

Grizzly bears ( Ursus arctos horribilis ) and black bears ( Ursus americanus ) prevent trabecular bone loss during disuse (hibernation)

by McGee-Lawrence, Meghan E, Wojda, Samantha J, Barlow, Lindsay N, Drummer, Thomas D, Castillo, Alesha B, Kennedy, Oran, Condon, Keith W, Auger, Janene, Black, Hal L, Nelson, O. Lynne, Robbins, Charles T, Donahue, Seth W
Published in Bone (New York, N.Y.)

Enhancer of zeste homolog 2 (Ezh2) controls bone formation and cell cycle progression during osteogenesis in mice

by Dudakovic, Amel, Camilleri, Emily T., Paradise, Christopher R., Samsonraj, Rebekah M., Gluscevic, Martina, Paggi, Carlo Alberto, Begun, Dana L., Khani, Farzaneh, Pichurin, Oksana, Ahmed, Farah S., Elsayed, Ranya, Elsalanty, Mohammed, McGee-Lawrence, Meghan E., Karperien, Marcel, Riester, Scott M., Thaler, Roman, Westendorf, Jennifer J., van Wijnen, Andre J.
Published in The Journal of biological chemistry

Kynurenine, a Tryptophan Metabolite That Increases with Age, Induces Muscle Atrophy and Lipid Peroxidation

by Kaiser, Helen, Yu, Kanglun, Pandya, Chirayu, Mendhe, Bharati, Isales, Carlos M., McGee-Lawrence, Meghan E., Johnson, Maribeth, Fulzele, Sadanand, Hamrick, Mark W.
Published in Oxidative medicine and cellular longevity

Orchiectomy sensitizes cortical bone in male mice to the harmful effects of kynurenine

by Bensreti, Husam, Yu, Kanglun, Alhamad, Dima W., Shaver, Joseph, Kaiser, Helen, Zhong, Roger, Whichard, William C., Parker, Emily, Grater, Lindsey, Faith, Hayden, Johnson, Maribeth, Cooley, Marion A., Fulzele, Sadanand, Hill, William D., Isales, Carlos M., Hamrick, Mark W., McGee-Lawrence, Meghan E.
Published in Bone (New York, N.Y.)

Kynurenine suppresses osteoblastic cell energetics in vitro and osteoblast numbers in vivo

by Pierce, Jessica L., Roberts, Rachel L., Yu, Kanglun, Kendall, Riley K., Kaiser, Helen, Davis, Colleen, Johnson, Maribeth H., Hill, William D., Isales, Carlos M., Bollag, Wendy B., Hamrick, Mark W., McGee-Lawrence, Meghan E.
Published in Experimental gerontology

Decreased bone turnover with balanced resorption and formation prevent cortical bone loss during disuse (hibernation) in grizzly bears ( Ursus arctos horribilis )

by McGee, Meghan E, Maki, Aaron J, Johnson, Steven E, Nelson, O. Lynne, Robbins, Charles T, Donahue, Seth W
Published in Bone (New York, N.Y.)

Sclerostin deficient mice rapidly heal bone defects by activating β-catenin and increasing intramembranous ossification

by McGee-Lawrence, Meghan E., Ryan, Zachary C., Carpio, Lomeli R., Kakar, Sanjeev, Westendorf, Jennifer J., Kumar, Rajiv
Published in Biochemical and biophysical research communications

Whole-Body Vibration Mimics the Metabolic Effects of Exercise in Male Leptin Receptor–Deficient Mice

by McGee-Lawrence, Meghan E, Wenger, Karl H, Misra, Sudipta, Davis, Catherine L, Pollock, Norman K, Elsalanty, Mohammed, Ding, Kehong, Isales, Carlos M, Hamrick, Mark W, Wosiski-Kuhn, Marlena, Arounleut, Phonepasong, Mattson, Mark P, Cutler, Roy G, Yu, Jack C, Stranahan, Alexis M
Published in Endocrinology (Philadelphia)

Conditional deletion of Hdac3 in osteoprogenitor cells attenuates diet-induced systemic metabolic dysfunction

by McGee-Lawrence, Meghan E., White, Thomas A., LeBrasseur, Nathan K., Westendorf, Jennifer J.
Published in Molecular and cellular endocrinology

Reply to vorinostat induced bone loss in mice

by Westendorf, Jennifer J, McGee-Lawrence, Meghan E
Published in Bone (New York, N.Y.)

Arctic Ground Squirrels Limit Bone Loss during the Prolonged Physical Inactivity Associated with Hibernation

by Wojda, Samantha J., Gridley, Richard A., McGee-Lawrence, Meghan E., Drummer, Thomas D., Hess, Ann, Kohl, Franziska, Barnes, Brian M., Donahue, Seth W.
Published in Physiological and biochemical zoology

Six months of disuse during hibernation does not increase intracortical porosity or decrease cortical bone geometry, strength, or mineralization in black bear ( Ursus americanus )...

by McGee-Lawrence, Meghan E, Wojda, Samantha J, Barlow, Lindsay N, Drummer, Thomas D, Bunnell, Kevin, Auger, Janene, Black, Hal L, Donahue, Seth W
Published in Journal of biomechanics

Reduced bone formation in males and increased bone resorption in females drive bone loss in hemophilia A mice

by Weitzmann, M. Neale, Roser-Page, Susanne, Vikulina, Tatyana, Weiss, Daiana, Hao, Li, Baldwin, W. Hunter, Yu, Kanglun, del Mazo Arbona, Natalia, McGee-Lawrence, Meghan E., Meeks, Shannon L., Kempton, Christine L.
Published in Blood advances

Black bear femoral geometry and cortical porosity are not adversely affected by ageing despite annual periods of disuse (hibernation)

by McGee, Meghan E., Miller, Danielle L., Auger, Janene, Black, Hal L., Donahue, Seth W.
Published in Journal of anatomy

Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma

by Satpathy, Shankha, Cao, Song, Dhanasekaran, Saravana M., Vasaikar, Suhas V., Petralia, Francesca, Liang, Wen-Wei, Krek, Azra, Hong, Runyu, Blumenberg, Lili, Wendl, Michael C., Wen, Bo, Tang, Lauren C., MacMullan, Melanie A., Kane, M. Harry, Newton, Chelsea J., Cornwell, MacIntosh, Yoo, Seungyeul, Mannan, Rahul, Vats, Pankaj, Kumar-Sinha, Chandan, Colaprico, Antonio, Geffen, Yifat, Wiznerowicz, Maciej, Gümüş, Zeynep H., Veluswamy, Rajwanth R., Hostetter, Galen, Mesri, Mehdi, Boja, Emily S., Omenn, Gilbert S., Thiagarajan, Mathangi, Getz, Gad, Cieslik, Marcin P., Govindan, Ramaswamy, Wang, Pei, Nesvizhskii, Alexey I., Ding, Li, Mani, D.R., Francis, Alicia, Charamut, Alyssa, Paulovich, Amanda G., Karnuta, Andrii, Hindenach, Barbara, Druker, Brian J., Birger, Chet, Jones, Corbin D., Rohrer, Daniel C., Zhou, Daniel Cui, Chan, Daniel W., Chesla, David, Clark, David J., Tan, Donghui, Duffy, Elizabeth, Bergstrom, Erik J., Wilson, George D., Chen, Hai-Quan, Sun, Hua, Whiteaker, Jeffrey R., Rodland, Karin D., Hoadley, Katherine A., Elburn, Kim, Hannick, Linda, Qi, Liqun, Sokoll, Lori J., Wojtyś, Małgorzata, Domagalski, Marcin J., Beasley, Mary B., Monroe, Matthew E., Ellis, Matthew J., Dyer, Maureen, Burke, Meghan C., Borucki, Melissa, Schnaubelt, Michael, Chaikin, Michelle, Selvan, Myvizhi Esai, McGarvey, Peter B., Thangudu, Ratna R., Smith, Richard D., Welsh, Robert J., Zelt, Robert, Mehra, Rohit, Matteotti, Ronald, Mareedu, Sailaja, Payne, Samuel H., Cottingham, Sandra, Chugh, Seema, Smith, Shaleigh, Tsang, Shirley, Cai, Shuang, Boca, Simina M., Stein, Stephen E., Krubit, Tanya, Skelly, Tara, Bauer, Thomas, Velvulou, Uma, Petyuk, Vladislav A., Bocik, William E., Maggio, William W., Chen, Xi, Wu, Yige, Shi, Zhiao
Published in Cell