Multimodal population brain imaging in the UK Biobank prospective epidemiological study

by Miller, Karla L, Alfaro-Almagro, Fidel, Bangerter, Neal K, Thomas, David L, Yacoub, Essa, Xu, Junqian, Bartsch, Andreas J, Jbabdi, Saad, Sotiropoulos, Stamatios N, Andersson, Jesper L R, Griffanti, Ludovica, Douaud, Gwenaëlle, Okell, Thomas W, Weale, Peter, Dragonu, Iulius, Garratt, Steve, Hudson, Sarah, Collins, Rory, Jenkinson, Mark, Matthews, Paul M, Smith, Stephen M
Published in Nature neuroscience

A structural variation reference for medical and population genetics

by Collins, Ryan L, Brand, Harrison, Karczewski, Konrad J, Zhao, Xuefang, Alföldi, Jessica, Francioli, Laurent C, Khera, Amit V, Lowther, Chelsea, Gauthier, Laura D, Wang, Harold, Watts, Nicholas A, Solomonson, Matthew, O'Donnell-Luria, Anne, Baumann, Alexander, Munshi, Ruchi, Walker, Mark, Whelan, Christopher W, Huang, Yongqing, Brookings, Ted, Sharpe, Ted, Stone, Matthew R, Valkanas, Elise, Fu, Jack, Tiao, Grace, Laricchia, Kristen M, Ruano-Rubio, Valentin, Stevens, Christine, Gupta, Namrata, Cusick, Caroline, Margolin, Lauren, Taylor, Kent D, Lin, Henry J, Rich, Stephen S, Post, Wendy S, Chen, Yii-Der Ida, Rotter, Jerome I, Nusbaum, Chad, Philippakis, Anthony, Lander, Eric, Gabriel, Stacey, Neale, Benjamin M, Kathiresan, Sekar, Daly, Mark J, Banks, Eric, MacArthur, Daniel G, Talkowski, Michael E
Published in Nature (London)

Effects of canagliflozin on amputation risk in type 2 diabetes: the CANVAS Program

by Matthews, David R., Li, Qiang, Perkovic, Vlado, Mahaffey, Kenneth W., de Zeeuw, Dick, Fulcher, Greg, Desai, Mehul, Hiatt, William R., Nehler, Mark, Fabbrini, Elisa, Kavalam, Mary, Lee, Mary, Neal, Bruce
Published in Diabetologia

Large-scale open-source three-dimensional growth curves for clinical facial assessment and objective description of facial dysmorphism

by Matthews, Harold S, Palmer, Richard L, Baynam, Gareth S, Quarrell, Oliver W, Klein, Ophir D, Spritz, Richard A, Hennekam, Raoul C, Walsh, Susan, Shriver, Mark, Weinberg, Seth M, Hallgrimsson, Benedikt, Hammond, Peter, Penington, Anthony J, Peeters, Hilde, Claes, Peter D
Published in Scientific reports

Patterns and Characteristics of Hepatitis C Transmission Clusters among HIV-Positive and HIV-Negative Individuals in the Australian Trial in Acute Hepatitis C

by Matthews, G. V., Pham, S. T., Hellard, M., Grebely, J., Zhang, L., Oon, A., Marks, P., van Beek, I., Rawlinson, W., Kaldor, J. M., Lloyd, A., Dore, G. J., White, P. A.
Published in Clinical infectious diseases

Increased mortality in community-tested cases of SARS-CoV-2 lineage B.1.1.7

by Davies, Nicholas G, Jarvis, Christopher I, Edmunds, W John, Jewell, Nicholas P, Diaz-Ordaz, Karla, Keogh, Ruth H
Published in Nature (London)

Mediators of the Effects of Canagliflozin on Heart Failure in Patients With Type 2 Diabetes

by Li, JingWei, Woodward, Mark, Perkovic, Vlado, Figtree, Gemma A., Heerspink, Hiddo J.L., Mahaffey, Kenneth W., de Zeeuw, Dick, Vercruysse, Frank, Shaw, Wayne, Matthews, David R., Neal, Bruce
Published in JACC. Heart failure

The Integrated Genomic Landscape of Thymic Epithelial Tumors

by Anur, Pavana, McLellan, Mike, Bowlby, Reanne, Hegde, Apurva M., Leiserson, Mark D.M., Sethi, Geetika, Ryan, Michael, Su, Xiaoping, Cherniack, Andrew D., Akbani, Rehan, Spellman, Paul, Weinstein, John N., Raphael, Ben, Zenklusen, Jean Claude, Ally, Adrian, Appelbaum, Elizabeth L., Balasundaram, Miruna, Behera, Madhusmita, Blandino, Giovanni, Bowen, Jay, Carlsen, Rebecca, Carvalho, Andre L., Chin, Lynda, Choe, Gina, Chudamani, Sudha, Cibulskis, Carrie, Cordes, Matthew G., Crain, Daniel, Curley, Erin, Defreitas, Timothy, Dienemann, Hendrik, Facciolo, Francesco, Ferguson, Martin L., Fulton, Robert S., Gabriel, Stacey B., Gardner, Johanna, Gehlenborg, Nils, Gerken, Mark, Getz, Gad, Heiman, David I., Holbrook, Andrea, Hoyle, Alan P., Jones, Corbin D., Jones, Steven J.M., Kasaian, Katayoon, Lai, Phillip H., Lawrence, Michael S., Lin, Pei, Lolla, Laxmi, Lu, Yiling, Ma, Yussanne, Mardis, Elaine R., Meister, Michael, Meng, Shaowu, Meyerson, Matthew, Mills, Gordon B., Moore, Richard A., Morris, Scott, Mose, Lisle E., Muley, Thomas, Naresh, Rashi, Newton, Yulia, Owonikoko, Taofeek, Paulaskis, Joseph, Perou, Charles M., Perrin, Corinne, Radenbaugh, Amie, Ramirez, Nilsa, Rieker, Ralf, Roach, Jeffrey, Sadeghi, Sara, Saksena, Gordon, Schein, Jacqueline E., Schumacher, Steven E., Shelton, Candace, Shi, Yan, Simons, Janae V., Sofia, Heidi J., Sun, Qiang, Tan, Donghui, Tarnuzzer, Roy, Van Den Berg, David J., Veluvolu, Umadevi, Walter, Vonn, Wang, Zhining, Warth, Arne, Weis, Cleo-Aron, Weisenberger, Daniel J., Wilkerson, Matthew D., Wu, Hsin-Ta, Wu, Ye, Zmuda, Erik, Hwang, David, Marino, Mirella, Gokmen-Polar, Yesim, Badve, Sunil, Rajan, Arun, Ströbel, Philipp, Tsao, Ming S., Loehrer, Patrick J.
Published in Cancer cell

Balanced Crystalloids versus Saline in the Intensive Care Unit. The SALT Randomized Trial

by Semler, Matthew W, Wanderer, Jonathan P, Ehrenfeld, Jesse M, Stollings, Joanna L, Self, Wesley H, Siew, Edward D, Wang, Li, Byrne, Daniel W, Shaw, Andrew D, Bernard, Gordon R, Rice, Todd W
Published in American journal of respiratory and critical care medicine

Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma

by Robertson, A. Gordon, Lichtenberg, Tara M., Else, Tobias, Ling, Shiyun, Jefferys, Stuart R., Wenz, Brandon, Korpershoek, Esther, Amelio, Antonio L., Makowski, Liza, Gimenez-Roqueplo, Anne-Paule, Amar, Laurence, Arachchi, Harindra, Asa, Sylvia L., Balasundaram, Miruna, Balu, Saianand, Benz, Christopher, Bodenheimer, Tom, Boice, Lori, Bowen, Jay, Brooks, Denise, Cherniack, Andrew D., Cho, Juok, Cope, Leslie, Danilova, Ludmila, Deutschbein, Timo, Dhalla, Noreen, Eng, Charis, Eschbacher, Jennifer, Fassnacht, Martin, Ferguson, Martin L., Fiddes, Ian, Fishbein, Lauren, Frazer, Scott, Gastier-Foster, Julie M., Getz, Gad, Ghayee, Hans K., Haussler, David, Hayes, D. Neil, Heiman, David I., Hoadley, Katherine A., Holt, Robert A., Huang, Mei, Johnson, Amy R., Jones, Steven J.M., Kebebew, Electron, Korpershoek, Esther, Lee, Darlene, Lerario, Antonio, Leshchiner, Ignaty, Lin, Pei, Liu, Jia, Lolla, Laxmi, Lotan, Yair, Lu, Yiling, Makowski, Liza, Mallery, David, Marra, Marco A., Merino, Maria J., Mete, Ozgur, Meyerson, Matthew, Morris, Scott, Mose, Lisle E., Naresh, Rashi, Newton, Yulia, Ng, Sam, Ni, Ying, Pacak, Karel, Paul, Evan, Penny, Robert, Pihl, Todd, Rao, Arjun, Roach, Jeffrey, Salama, Sofie, Saller, Charles, Sandusky, George, Sbiera, Silviu, Schein, Jacqueline E., Schumacher, Steven E., Shelton, Candace, Shelton, Troy, Sokolov, Artem, Soloway, Matthew G., Thorne, Leigh B., Timmers, Henri J., Tse, Kane, van Berkel, Anouk, Veluvolu, Umadevi, Voet, Doug, Wan, Yunhu, Wang, Tracy S., Weinstein, John N., Wenz, Brandon, Wilkerson, Matthew D., Wise, Lisa, Wong, Christopher, Zhang, Jiashan (Julia), Zhu, Jingchun, Zmuda, Erik, Pacak, Karel, Wilkerson, Matthew D.
Published in Cancer cell

MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C

by Thabet, Khaled, Asimakopoulos, Anastasia, Shojaei, Maryam, Romero-Gomez, Manuel, Mangia, Alessandra, Irving, William L, Berg, Thomas, Dore, Gregory J, Grønbæk, Henning, Sheridan, David, Abate, Maria Lorena, Bugianesi, Elisabetta, Weltman, Martin, Mollison, Lindsay, Cheng, Wendy, Riordan, Stephen, Fischer, Janett, Spengler, Ulrich, Nattermann, Jacob, Wahid, Ahmed, Rojas, Angela, White, Rose, Douglas, Mark W, McLeod, Duncan, Powell, Elizabeth, Liddle, Christopher, van der Poorten, David, George, Jacob, Eslam, Mohammed
Published in Nature communications

Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits

by Speliotes, Elizabeth K, Yerges-Armstrong, Laura M, Wu, Jun, Hernaez, Ruben, Kim, Lauren J, Palmer, Cameron D, Gudnason, Vilmundur, Eiriksdottir, Gudny, Garcia, Melissa E, Launer, Lenore J, Nalls, Michael A, Clark, Jeanne M, Mitchell, Braxton D, Shuldiner, Alan R, Butler, Johannah L, Tomas, Marta, Hoffmann, Udo, Hwang, Shih-Jen, Massaro, Joseph M, O'Donnell, Christopher J, Sahani, Dushyant V, Salomaa, Veikko, Schadt, Eric E, Schwartz, Stephen M, Siscovick, David S, Voight, Benjamin F, Carr, J Jeffrey, Feitosa, Mary F, Harris, Tamara B, Fox, Caroline S, Smith, Albert V, Kao, W H Linda, Hirschhorn, Joel N, Borecki, Ingrid B
Published in PLoS genetics

Moving away from Ritonavir, Abacavir, Tenofovir, and Efavirenz (RATE)--agents that concern prescribers and patients: a feasibility study and call for a trial

by Achhra, Amit C, Boyd, Mark A, Law, Matthew G, Matthews, Gail V, Kelleher, Anthony D, Cooper, David A
Published in PloS one

Effect of Intravenous Tenecteplase Dose on Cerebral Reperfusion Before Thrombectomy in Patients With Large Vessel Occlusion Ischemic Stroke: The EXTEND-IA TNK Part 2 Randomized Cli...

by Campbell, Bruce C. V, Mitchell, Peter J, Churilov, Leonid, Yassi, Nawaf, Kleinig, Timothy J, Dowling, Richard J, Yan, Bernard, Bush, Steven J, Thijs, Vincent, Scroop, Rebecca, Simpson, Marion, Brooks, Mark, Asadi, Hamed, Wu, Teddy Y, Shah, Darshan G, Wijeratne, Tissa, Zhao, Henry, Alemseged, Fana, Ng, Felix, Bailey, Peter, Rice, Henry, de Villiers, Laetitia, Dewey, Helen M, Choi, Philip M. C, Brown, Helen, Redmond, Kendal, Leggett, David, Fink, John N, Collecutt, Wayne, Kraemer, Thomas, Krause, Martin, Cordato, Dennis, Field, Deborah, Ma, Henry, O’Brien, Bill, Clissold, Benjamin, Miteff, Ferdinand, Clissold, Anna, Cloud, Geoffrey C, Bolitho, Leslie E, Bonavia, Luke, Bhattacharya, Arup, Wright, Alistair, Mamun, Abul, O’Rourke, Fintan, Worthington, John, Wong, Andrew A, Levi, Christopher R, Bladin, Christopher F, Sharma, Gagan, Desmond, Patricia M, Parsons, Mark W, Donnan, Geoffrey A, Davis, Stephen M
Published in JAMA : the journal of the American Medical Association

The Effect of Lifestyle Intervention and Metformin on Preventing or Delaying Diabetes Among Women With and Without Gestational Diabetes: The Diabetes Prevention Program Outcomes St...

by Aroda, V. R, Christophi, C. A, Edelstein, S. L, Zhang, P, Herman, W. H, Barrett-Connor, E, Delahanty, L. M, Montez, M. G, Ackermann, R. T, Zhuo, X, Knowler, W. C, Ratner, R. E, for the Diabetes Prevention Program Research Group
Published in The journal of clinical endocrinology and metabolism

Percutaneous Left Atrial Appendage Closure vs Warfarin for Atrial Fibrillation: A Randomized Clinical Trial

by Reddy, Vivek Y, Sievert, Horst, Halperin, Jonathan, Doshi, Shephal K, Buchbinder, Maurice, Neuzil, Petr, Huber, Kenneth, Whisenant, Brian, Kar, Saibal, Swarup, Vijay, Gordon, Nicole, Holmes, David
Published in JAMA : the journal of the American Medical Association

Common genetic determinants of intraocular pressure and primary open-angle glaucoma

by van Koolwijk, Leonieke M E, Ramdas, Wishal D, Ikram, M Kamran, Jansonius, Nomdo M, Pasutto, Francesca, Hysi, Pirro G, Macgregor, Stuart, Janssen, Sarah F, Hewitt, Alex W, Viswanathan, Ananth C, ten Brink, Jacoline B, Hosseini, S Mohsen, Amin, Najaf, Despriet, Dominiek D G, Willemse-Assink, Jacqueline J M, Kramer, Rogier, Rivadeneira, Fernando, Struchalin, Maksim, Aulchenko, Yurii S, Weisschuh, Nicole, Zenkel, Matthias, Mardin, Christian Y, Gramer, Eugen, Welge-Lüssen, Ulrich, Montgomery, Grant W, Carbonaro, Francis, Young, Terri L, Bellenguez, Céline, McGuffin, Peter, Foster, Paul J, Topouzis, Fotis, Mitchell, Paul, Wang, Jie Jin, Wong, Tien Y, Czudowska, Monika A, Hofman, Albert, Uitterlinden, Andre G, Wolfs, Roger C W, de Jong, Paulus T V M, Oostra, Ben A, Paterson, Andrew D, Mackey, David A, Bergen, Arthur A B, Reis, André, Hammond, Christopher J, Vingerling, Johannes R, Lemij, Hans G, Klaver, Caroline C W, van Duijn, Cornelia M
Published in PLoS genetics

Pharmacodynamics, Pharmacokinetics, Safety, and Tolerability of Albiglutide, a Long-Acting Glucagon-Like Peptide-1 Mimetic, in Patients with Type 2 Diabetes

by Matthews, Jessica E, Stewart, Murray W, De Boever, Erika H, Dobbins, Robert L, Hodge, Rebecca J, Walker, Susan E, Holland, M. Claire, Bush, Mark A
Published in The journal of clinical endocrinology and metabolism

Low-Dose Dopamine or Low-Dose Nesiritide in Acute Heart Failure With Renal Dysfunction: The ROSE Acute Heart Failure Randomized Trial

by Chen, Horng H, Anstrom, Kevin J, Givertz, Michael M, Stevenson, Lynne W, Semigran, Marc J, Goldsmith, Steven R, Bart, Bradley A, Bull, David A, Stehlik, Josef, LeWinter, Martin M, Konstam, Marvin A, Huggins, Gordon S, Rouleau, Jean L, O'Meara, Eileen, Tang, W. H. Wilson, Starling, Randall C, Butler, Javed, Deswal, Anita, Felker, G. Michael, O'Connor, Christopher M, Bonita, Raphael E, Margulies, Kenneth B, Cappola, Thomas P, Ofili, Elizabeth O, Mann, Douglas L, Dávila-Román, Víctor G, McNulty, Steven E, Borlaug, Barry A, Velazquez, Eric J, Lee, Kerry L, Shah, Monica R, Hernandez, Adrian F, Braunwald, Eugene, Redfield, Margaret M
Published in JAMA : the journal of the American Medical Association

Comparison of an Everolimus-Eluting Stent and a Paclitaxel-Eluting Stent in Patients With Coronary Artery Disease: A Randomized Trial

by Stone, Gregg W, Midei, Mark, Newman, William, Sanz, Mark, Hermiller, James B, Williams, Jerome, Farhat, Naim, Mahaffey, Kenneth W, Cutlip, Donald E, Fitzgerald, Peter J, Sood, Poornima, Su, Xiaolu, Lansky, Alexandra J, SPIRIT III Investigators, for the
Published in JAMA : the journal of the American Medical Association