CD25+ Natural Regulatory T Cells Are Critical in Limiting Innate and Adaptive Immunity and Resolving Disease following Respiratory Syncytial Virus Infection

by Lee, Debbie C P, Harker, James A E, Tregoning, John S, Atabani, Sowsan F, Johansson, Cecilia, Schwarze, Jürgen, Openshaw, Peter J M
Published in Journal of Virology

Prior exposure to inhaled allergen enhances anti-viral immunity and T cell priming by dendritic cells

by Lee, Debbie C P, Tay, Neil Q, Thian, Marini, Prabhu, Nayana, Furuhashi, Kazuki, Kemeny, David M
Published in PloS one

Gamma Interferon Regulates Contraction of the Influenza Virus-Specific CD8 T Cell Response and Limits the Size of the Memory Population

by Prabhu, Nayana, Ho, Adrian W, Wong, Kenneth H S, Hutchinson, Paul Edward, Chua, Yen Leong, Kandasamy, Matheswaran, Lee, Debbie C P, Sivasankar, Baalasubramanian, Kemeny, David Michael
Published in Journal of Virology

Interleukin 18 Coexpression during Respiratory Syncytial Virus Infection Results in Enhanced Disease Mediated by Natural Killer Cells

by HARKER, James A, GODLEE, Alexandra, OPENSHAW, Peter J. M, WAHLSTEN, Jennifer L, LEE, Debbie C. P, THORNE, Lucy G, SAWANT, Devika, TREGONING, John S, CASPI, Rachel R, BUKREYEV, Alexander, COLLINS, Peter L
Published in Journal of Virology

Delivery of Cytokines by Recombinant Virus in Early Life Alters the Immune Response to Adult Lung Infection

by HARKER, James A, LEE, Debbie C. P, YAMAGUCHI, Yuko, WANG, Belinda, BUKREYEV, Alexander, COLLINS, Peter L, TREGONING, John S, OPENSHAW, Peter J. M
Published in Journal of Virology

CD40L Expression Allows CD8 + T Cells to Promote Their Own Expansion and Differentiation through Dendritic Cells

by Tay, Neil Q, Lee, Debbie C P, Chua, Yen Leong, Prabhu, Nayana, Gascoigne, Nicholas R J, Kemeny, David M
Published in Frontiers in immunology

Priming with high and low respiratory allergen dose induces differential CD4+ T helper type 2 cells and IgE/IgG1 antibody responses in mice

by Furuhashi, Kazuki, Chua, Yen L., Wong, Kenneth H. S., Zhou, Qian, Lee, Debbie C. P., Liong, Ka H., Teo, Guo H., Hutchinson, Paul E., Kemeny, David M.
Published in Immunology

Perinatal paracetamol exposure in mice does not affect the development of allergic airways disease in early life

by Lee, Debbie C P, Walker, Simone A, Byrne, Adam J, Gregory, Lisa G, Buckley, James, Bush, Andrew, Shaheen, Seif O, Saglani, Sejal, Lloyd, Clare M
Published in Thorax

CD40L signaling from CD8+ T cells confers protection against influenza infection

by Tay, Neil Q, Lee, Debbie C P, Chua, Yen Leong, Prabhu, Nayana, Kemeny, David Michael
Published in The Journal of immunology (1950)

Lentivector-mediated SMN replacement in a mouse model of spinal muscular atrophy

by Azzouz, Mimoun, Le, Thanh, Ralph, G Scott, Walmsley, Lucy, Monani, Umrao R, Lee, Debbie C P, Wilkes, Fraser, Mitrophanous, Kyriacos A, Kingsman, Susan M, Burghes, Arthur H M, Mazarakis, Nicholas D
Published in The Journal of clinical investigation

Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias

by Clarke, Robert, Bennett, Derrick A, Parish, Sarah, Verhoef, Petra, Dötsch-Klerk, Mariska, Lathrop, Mark, Xu, Peng, Nordestgaard, Børge G, Holm, Hilma, Hopewell, Jemma C, Saleheen, Danish, Tanaka, Toshihiro, Anand, Sonia S, Chambers, John C, Kleber, Marcus E, Ouwehand, Willem H, Yamada, Yoshiji, Elbers, Clara, Peters, Bas, Stewart, Alexandre F R, Reilly, Muredach M, Thorand, Barbara, Yusuf, Salim, Engert, James C, Assimes, Themistocles L, Kooner, Jaspal, Danesh, John, Watkins, Hugh, Samani, Nilesh J, Collins, Rory, Peto, Richard
Published in PLoS medicine

Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised...

by Kandzari, David E, Böhm, Michael, Mahfoud, Felix, Townsend, Raymond R, Weber, Michael A, Pocock, Stuart, Tsioufis, Konstantinos, Tousoulis, Dimitrios, Choi, James W, East, Cara, Brar, Sandeep, Cohen, Sidney A, Fahy, Martin, Pilcher, Garrett, Kario, Kazuomi, Aoki, Jiro, Batson, Bryan, Böhm, Michael, Choi, James W., Cohen, Debbie L., Dangas, George, David, Shukri, Davies, Justin, Devireddy, Chandan M., Kandzari, David, Kario, Kazuomi, Lee, David P., Lurz, Philipp C., Papademetriou, Vasilios, Patel, Manesh, Patel, Kiritkumar, Schmieder, Roland E., Sharp, Andrew S.P., Singh, Jasvindar, Tsioufis, Konstantinos, Walton, Antony, Weber, Thomas, Weil, Joachim, Zeller, Thomas, Ziada, Khaled, Tanabe, Kengo, Wilkins, Robert, Mahfoud, Felix, East, Cara, Wilensky, Robert, Contreras, Johanna, Steigerwalt, Susan, Chapman, Neil, Lea, Janice P., Reedus, Denise, Hoshide, Satoshi, Ma, Adrian, Fengler, Karl, Li, Ping, Svetkey, Laura, Rao, Anjani, Schmid, Axel, Watkinson, Anthony F, Brown, Angela, Tousoulis, Dimitrios, Hopper, Ingrid, Suppan, Markus, Agdirlioglu, Tolga, Noory, Elias, Chasen, Craig
Published in The Lancet (British edition)

Chemokine Receptor 2-targeted Molecular Imaging in Pulmonary Fibrosis. A Clinical Trial

by Brody, Steven L, Gunsten, Sean P, Luehmann, Hannah P, Sultan, Debbie H, Hoelscher, Michelle, Heo, Gyu Seong, Pan, Jiehong, Koenitzer, Jeffrey R, Lee, Ethan C, Huang, Tao, Mpoy, Cedric, Guo, Shuchi, Laforest, Richard, Salter, Amber, Russell, Tonya D, Shifren, Adrian, Combadiere, Christophe, Lavine, Kory J, Kreisel, Daniel, Humphreys, Benjamin D, Rogers, Buck E, Gierada, David S, Byers, Derek E, Gropler, Robert J, Chen, Delphine L, Atkinson, Jeffrey J, Liu, Yongjian
Published in American journal of respiratory and critical care medicine

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

by Johnson, Laura A., Morgan, Richard A., Dudley, Mark E., Cassard, Lydie, Yang, James C., Hughes, Marybeth S., Kammula, Udai S., Royal, Richard E., Sherry, Richard M., Wunderlich, John R., Lee, Chyi-Chia R., Restifo, Nicholas P., Schwarz, Susan L., Cogdill, Alexandria P., Bishop, Rachel J., Kim, Hung, Brewer, Carmen C., Rudy, Susan F., VanWaes, Carter, Davis, Jeremy L., Mathur, Aarti, Ripley, Robert T., Nathan, Debbie A., Laurencot, Carolyn M., Rosenberg, Steven A.
Published in Blood

Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised, sham-controlled, proo...

by Townsend, Raymond R, Mahfoud, Felix, Kandzari, David E, Kario, Kazuomi, Pocock, Stuart, Weber, Michael A, Ewen, Sebastian, Tsioufis, Konstantinos, Tousoulis, Dimitrios, Sharp, Andrew S P, Watkinson, Anthony F, Schmieder, Roland E, Schmid, Axel, Choi, James W, East, Cara, Walton, Anthony, Hopper, Ingrid, Cohen, Debbie L, Wilensky, Robert, Lee, David P, Ma, Adrian, Devireddy, Chandan M, Lea, Janice P, Lurz, Philipp C, Fengler, Karl, Davies, Justin, Chapman, Neil, Cohen, Sidney A, DeBruin, Vanessa, Fahy, Martin, Jones, Denise E, Rothman, Martin, Böhm, Michael, Aoki, Jiro, Batson, Bryan, Böhm, Michael, Choi, James W, Cohen, Debbie L, Dangas, George, David, Shukri, Davies, Justin, Devireddy, Chandan M, Kandzari, David, Kario, Kazuomi, Lee, David P, Lurz, Philipp C, Patel, Manesh, Patel, Kiritkumar, Schmieder, Roland E, Sharp, Andrew S P, Singh, Jasvindar, Tsioufis, Konstantinos, Walton, Anthony, Weber, Thomas, Weil, Joachim, Zeller, Thomas, Ziada, Khaled, Tanabe, Kengo, Wilkins, Robert, Mahfoud, Felix, East, Cara, Wilensky, Robert, Contreras, Johanna, Steigerwalt, Susan, Chapman, Neil, Lea, Janice P, Reedus, Denise, Hoshide, Satoshi, Ma, Adrian, Fengler, Karl, Svetkey, Laura, Rao, Anjani, Schmid, Axel, Watkinson, Anthony F, Brown, Angela, Tousoulis, Dimitrios, Hopper, Ingrid, Suppan, Markus, Agdirlioglu, Tolga, Noory, Elias, Chasen, Craig
Published in The Lancet (British edition)

Implementing core outcomes in kidney disease: report of the Standardized Outcomes in Nephrology (SONG) implementation workshop

by Manns, Braden, Wheeler, David C., Gill, John, Pecoits-Filho, Robert, Winkelmayer, Wolfgang C., Perkovic, Vlado, Ju, Angela, Josephson, Michelle A., Johnson, David W., Craig, Jonathan C., Wang, Angela, Hemmelgarn, Brenda, Wheeler, David, Gill, John, Tugwell, Peter, van Biesen, Wim, Winkelmayer, Wolfgang, Levin, Adeera, Sinha, Aditi, Ong, Albert, Dart, Allison, Eddy, Allison, Viecelli, Andrea, Davenport, Andrew, Sharma, Ankit, Warrens, Anthony, Chapman, Arlene, Murphy, Barbara, Sautenet, Benedicte, Padilla, Benita, Pullin, Brian, Robinson, Bruce, Hanson, Camilla, Hawley, Carmel, Logeman, Charlotte, Herzog, Chuck, Ahn, Curie, Rosenbloom, David, Harris, David, Johnson, David, Fouque, Denis, Bockenhauer, Detlef, O'Donoghue, Donal, Chen, Dongping, Brown, Edwina, Bavlovlenkov, Elena, Poggio, Emilo, Chemla, Eric, Tentori, Francesca, Feldman, Harold, Coolican, Helen, Groothoff, Jaap, Sloand, James, Tan, Jane, Locke, Jayme, Perl, Jeffrey, Shen, Jenny, Fox, Jonathan, Dapueto, Juan, Tze-Wah Kao, Juliana, Chow, Kai Ming, Manera, Karine, Polkinghorne, Kevan, Fowler, Kevin, Van, Kim Linh, Hooi, Lai-Seong, James, Laura, Dember, Laura, Rostaing, Lionel, Marson, Lorna, Hamiwka, Lorraine, Krishnan, Mahesh, Ruospo, Marinella, Jardine, Meg, Zappitelli, Michael, Germain, Michael, Webb, Nick, Gedney, Nieltje, Reese, Peter, Roy-Chaudhury, Prabir, Oberbauer, Rainer, McGee, Richard, Gansevoort, Ron, Perrone, Ronald, Davison, Sara, Bernays, Sarah, Naiker, Sarala, Jowsey-Gregoire, Sheila, Stuard, Stefano, Alexander, Stephen, McDonald, Stephen, Gutman, Talia, Shafi, Tariq, Jafar, Tazeen, Hiemstra, Thomas, Krane, Vera, Herrington, Will, Cho, Yeoungjee, Oh, Yoonkyu, Butt, Zeeshan
Published in Kidney international

Actionable exomic incidental findings in 6503 participants: challenges of variant classification

by Amendola, Laura M, Dorschner, Michael O, Robertson, Peggy D, Salama, Joseph S, Hart, Ragan, Shirts, Brian H, Murray, Mitzi L, Tokita, Mari J, Gallego, Carlos J, Kim, Daniel Seung, Bennett, James T, Crosslin, David R, Ranchalis, Jane, Jones, Kelly L, Rosenthal, Elisabeth A, Jarvik, Ella R, Itsara, Andy, Turner, Emily H, Herman, Daniel S, Schleit, Jennifer, Burt, Amber, Jamal, Seema M, Abrudan, Jenica L, Johnson, Andrew D, Conlin, Laura K, Dulik, Matthew C, Santani, Avni, Metterville, Danielle R, Kelly, Melissa, Foreman, Ann Katherine M, Lee, Kristy, Taylor, Kent D, Guo, Xiuqing, Crooks, Kristy, Kiedrowski, Lesli A, Raffel, Leslie J, Gordon, Ora, Machini, Kalotina, Desnick, Robert J, Biesecker, Leslie G, Lubitz, Steven A, Mulchandani, Surabhi, Cooper, Greg M, Joffe, Steven, Richards, C Sue, Yang, Yaoping, Rotter, Jerome I, Rich, Stephen S, O'Donnell, Christopher J, Berg, Jonathan S, Spinner, Nancy B, Evans, James P, Fullerton, Stephanie M, Leppig, Kathleen A, Bennett, Robin L, Bird, Thomas, Sybert, Virginia P, Grady, William M, Tabor, Holly K, Kim, Jerry H, Bamshad, Michael J, Wilfond, Benjamin, Motulsky, Arno G, Scott, C Ronald, Pritchard, Colin C, Walsh, Tom D, Burke, Wylie, Raskind, Wendy H, Byers, Peter, Hisama, Fuki M, Rehm, Heidi, Nickerson, Debbie A, Jarvik, Gail P
Published in Genome research

Pharmacokinetics of morphine in encephalopathic neonates treated with therapeutic hypothermia

by Favié, Laurent M A, Groenendaal, Floris, van den Broek, Marcel P H, Rademaker, Carin M A, de Haan, Timo R, van Straaten, Henrica L M, Dijk, Peter H, van Heijst, Arno, Dudink, Jeroen, Dijkman, Koen P, Rijken, Monique, Zonnenberg, Inge A, Cools, Filip, Zecic, Alexandra, van der Lee, Johanna H, Nuytemans, Debbie H G M, van Bel, Frank, Egberts, Toine C G, Huitema, Alwin D R
Published in PloS one

Metabolite changes in blood predict the onset of tuberculosis

by Weiner, 3rd, January, Maertzdorf, Jeroen, Sutherland, Jayne S, Duffy, Fergal J, Thompson, Ethan, Suliman, Sara, McEwen, Gayle, Thiel, Bonnie, Parida, Shreemanta K, Zyla, Joanna, Hanekom, Willem A, Mohney, Robert P, Boom, W Henry, Mayanja-Kizza, Harriet, Howe, Rawleigh, Dockrell, Hazel M, Ottenhoff, Tom H M, Scriba, Thomas J, Zak, Daniel E, Walzl, Gerhard, Kaufmann, Stefan H E
Published in Nature communications

Genome sequencing and analysis of the model grass Brachypodium distachyon

by Salse, Jerome J., Murat, Florent, Abrouk, Michaël M., Chapman, Elisabeth E.J., Sibout, Richard, Hematy, Kian K., Mouille, Gregory G., Höfte, Hermanus H., Belcram, Harry H., Charles, Mathieu, Chalhoub, Boulos B.
Published in Nature (London)