Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens

by Hart, Traver, Tong, Amy Hin Yan, Chan, Katie, Van Leeuwen, Jolanda, Seetharaman, Ashwin, Aregger, Michael, Chandrashekhar, Megha, Hustedt, Nicole, Seth, Sahil, Noonan, Avery, Habsid, Andrea, Sizova, Olga, Nedyalkova, Lyudmila, Climie, Ryan, Tworzyanski, Leanne, Lawson, Keith, Sartori, Maria Augusta, Alibeh, Sabriyeh, Tieu, David, Masud, Sanna, Mero, Patricia, Weiss, Alexander, Brown, Kevin R, Usaj, Matej, Billmann, Maximilian, Rahman, Mahfuzur, Constanzo, Michael, Myers, Chad L, Andrews, Brenda J, Boone, Charles, Durocher, Daniel, Moffat, Jason
Published in G3 : genes - genomes - genetics

Disability, pain, and wound-specific concerns self-reported by adults at risk of limb loss: A cross-sectional study using the World Health Organization Disability Assessment Schedu...

by Roberts, Derek J, Nagpal, Sudhir K, Forster, Alan J, Brandys, Timothy, Murphy, Christine, Jennings, Alison, Strauss, Shira A, Vishnyakova, Evgeniya, Lawson, Julie, McIsaac, Daniel I
Published in PloS one

Discovery of AZD9833, a Potent and Orally Bioavailable Selective Estrogen Receptor Degrader and Antagonist

by Scott, James S, Moss, Thomas A, Balazs, Amber, Barlaam, Bernard, Breed, Jason, Carbajo, Rodrigo J, Chiarparin, Elisabetta, Davey, Paul R. J, Delpuech, Oona, Fawell, Stephen, Fisher, David I, Gagrica, Sladjana, Gangl, Eric T, Grebe, Tyler, Greenwood, Ryan D, Hande, Sudhir, Hatoum-Mokdad, Holia, Herlihy, Kara, Hughes, Samantha, Hunt, Thomas A, Huynh, Hoan, Janbon, Sophie L. M, Johnson, Tony, Kavanagh, Stefan, Klinowska, Teresa, Lawson, Mandy, Lister, Andrew S, Marden, Stacey, McGinnity, Dermot F, Morrow, Christopher J, Nissink, J. Willem M, O’Donovan, Daniel H, Peng, Bo, Polanski, Radoslaw, Stead, Darren S, Stokes, Stephen, Thakur, Kumar, Throner, Scott R, Tucker, Michael J, Varnes, Jeffrey, Wang, Haixia, Wilson, David M, Wu, Dedong, Wu, Ye, Yang, Bin, Yang, Wenzhan
Published in Journal of medicinal chemistry

Ensembl Genomes 2016: more genomes, more complexity

by Kersey, Paul Julian, Allen, James E., Armean, Irina, Boddu, Sanjay, Bolt, Bruce J., Carvalho-Silva, Denise, Christensen, Mikkel, Davis, Paul, Falin, Lee J., Grabmueller, Christoph, Humphrey, Jay, Kerhornou, Arnaud, Khobova, Julia, Aranganathan, Naveen K., Langridge, Nicholas, Lowy, Ernesto, McDowall, Mark D., Maheswari, Uma, Nuhn, Michael, Ong, Chuang Kee, Overduin, Bert, Paulini, Michael, Pedro, Helder, Perry, Emily, Spudich, Giulietta, Tapanari, Electra, Walts, Brandon, Williams, Gareth, Tello–Ruiz, Marcela, Stein, Joshua, Wei, Sharon, Ware, Doreen, Bolser, Daniel M., Howe, Kevin L., Kulesha, Eugene, Lawson, Daniel, Maslen, Gareth, Staines, Daniel M.
Published in Nucleic acids research

Temporal and spatial variation in distribution of fish environmental DNA in England’s largest lake

by Lawson Handley, Lori, Read, Daniel S., Winfield, Ian J., Kimbell, Helen, Johnson, Harriet, Li, Jianlong, Hahn, Christoph, Blackman, Rosetta, Wilcox, Rose, Donnelly, Rob, Szitenberg, Amir, Hänfling, Bernd
Published in Environmental DNA (Hoboken, N.J.)

T cell receptor sequencing of activated CD8 T cells in the blood identifies tumor-infiltrating clones that expand after PD-1 therapy and radiation in a melanoma patient

by Wieland, Andreas, Kamphorst, Alice O., Adsay, N. Volkan, Masor, Jonathan J., Sarmiento, Juan, Nasti, Tahseen H., Darko, Sam, Douek, Daniel C., Xue, Yue, Curran, Walter J., Lawson, David H., Ahmed, Rafi
Published in Cancer Immunology, Immunotherapy

In situ genotyping of a pooled strain library after characterizing complex phenotypes

by Lawson, Michael J, Camsund, Daniel, Larsson, Jimmy, Baltekin, Özden, Fange, David, Elf, Johan
Published in Molecular systems biology

Estrogen defines the dorsal-ventral limit of VEGF regulation to specify the location of the hemogenic endothelial niche

by Carroll, Kelli J, Esain, Virginie, Garnaas, Maija K, Cortes, Mauricio, Dovey, Michael C, Nissim, Sahar, Frechette, Gregory M, Liu, Sarah Y, Kwan, Wanda, Cutting, Claire C, Harris, James M, Gorelick, Daniel A, Halpern, Marnie E, Lawson, Nathan D, Goessling, Wolfram, North, Trista E
Published in Developmental cell

Cognitive decline and quality of life in incident Parkinson's disease: The role of attention

by Lawson, Rachael A, Yarnall, Alison J, Duncan, Gordon W, Breen, David P, Khoo, Tien K, Williams-Gray, Caroline H, Barker, Roger A, Collerton, Daniel, Taylor, John-Paul, Burn, David J
Published in Parkinsonism & related disorders

Ensembl Genomes: an integrative resource for genome-scale data from non-vertebrate species

by Kersey, Paul J, Staines, Daniel M, Lawson, Daniel, Kulesha, Eugene, Derwent, Paul, Humphrey, Jay C, Hughes, Daniel S. T, Keenan, Stephan, Kerhornou, Arnaud, Koscielny, Gautier, Langridge, Nicholas, McDowall, Mark D, Megy, Karine, Maheswari, Uma, Nuhn, Michael, Paulini, Michael, Pedro, Helder, Toneva, Iliana, Wilson, Derek, Yates, Andrew, Birney, Ewan
Published in Nucleic acids research

Ensembl Genomes 2013: scaling up access to genome-wide data

by Kersey, Paul Julian, Allen, James E, Christensen, Mikkel, Davis, Paul, Falin, Lee J, Grabmueller, Christoph, Hughes, Daniel Seth Toney, Humphrey, Jay, Kerhornou, Arnaud, Khobova, Julia, Langridge, Nicholas, McDowall, Mark D, Maheswari, Uma, Maslen, Gareth, Nuhn, Michael, Ong, Chuang Kee, Paulini, Michael, Pedro, Helder, Toneva, Iliana, Tuli, Mary Ann, Walts, Brandon, Williams, Gareth, Wilson, Derek, Youens-Clark, Ken, Monaco, Marcela K, Stein, Joshua, Wei, Xuehong, Ware, Doreen, Bolser, Daniel M, Howe, Kevin Lee, Kulesha, Eugene, Lawson, Daniel, Staines, Daniel Michael
Published in Nucleic acids research

Targeting glycogen synthase kinase 3 for therapeutic benefit in lymphoma

by Wu, Xiaosheng, Stenson, Mary, Abeykoon, Jithma, Nowakowski, Kevin, Zhang, Lianwen, Lawson, Joshua, Wellik, Linda, Li, Ying, Krull, Jordan, Wenzl, Kerstin, Novak, Anne J., Ansell, Stephen M., Bishop, Gail A., Billadeau, Daniel D., Peng, Kah Whye, Giles, Francis, Schmitt, Daniel M., Witzig, Thomas E.
Published in Blood

Microsomal Prostaglandin E Synthase-1 Deletion Suppresses Oxidative Stress and Angiotensin II-Induced Abdominal Aortic Aneurysm Formation

by MIAO WANG, LEE, Eric, WENLIANG SONG, RICCIOTTI, Emanuela, RADER, Daniel J, LAWSON, John A, PURE, Ellen, FITZGERALD, Garret A
Published in Circulation (New York, N.Y.)

Antibody Status and Incidence of SARS-CoV-2 Infection in Health Care Workers

by Lumley, Sheila F, Denise O’Donnell, Stoesser, Nicole E, Matthews, Philippa C, Howarth, Alison, Hatch, Stephanie B, Marsden, Brian D, Cox, Stuart, James, Tim, Warren, Fiona, Peck, Liam J, Ritter, Thomas G, de Toledo, Zoe, Warren, Laura, Axten, David, Cornall, Richard J, Jones, E Yvonne, Stuart, David I, Screaton, Gavin, Ebner, Daniel, Hoosdally, Sarah, Chand, Meera, Crook, Derrick W, Anne-Marie O’Donnell, Conlon, Christopher P, Pouwels, Koen B, Walker, A Sarah, Tim E.A. Peto, Hopkins, Susan, Walker, Timothy M, Jeffery, Katie, Eyre, David W
Published in New England Journal of Medicine

VectorBase: an updated bioinformatics resource for invertebrate vectors and other organisms related with human diseases

by Giraldo-Calderón, Gloria I, Emrich, Scott J, MacCallum, Robert M, Maslen, Gareth, Dialynas, Emmanuel, Topalis, Pantelis, Ho, Nicholas, Gesing, Sandra, Madey, Gregory, Collins, Frank H, Lawson, Daniel
Published in Nucleic acids research

Experience and modification update for the minimally invasive Nuss technique for pectus excavatum repair in 303 patients

by Croitoru, Daniel P., Kelly, Robert E., Goretsky, Michael J., Lawson, M.Louise, Swoveland, Barbara, Nuss, Donald
Published in Journal of pediatric surgery

Genetic and childhood trauma interaction effect on age of onset in bipolar disorder: An exploratory analysis

by Anand, Amit, Koller, Daniel L, Lawson, William B, Gershon, Elliot S, Nurnberger, John I
Published in Journal of affective disorders

Delirium is more common and associated with worse outcomes in Parkinson's disease compared to older adult controls: results of two prospective longitudinal cohort studies

by Gerakios, Florence, Yarnall, Alison J, Bate, Gemma, Wright, Laura, Davis, Daniel, Stephan, Blossom C M, Robinson, Louise, Brayne, Carol, Stebbins, Glenn, Taylor, John-Paul, Burn, David J, Allan, Louise M, Richardson, Sarah J, Lawson, Rachael A
Published in Age and ageing

VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center

by Amos, Beatrice, Aurrecoechea, Cristina, Barba, Matthieu, Barreto, Ana, Basenko, Evelina Y, Bażant, Wojciech, Belnap, Robert, Blevins, Ann S, Böhme, Ulrike, Brestelli, John, Brunk, Brian P, Caddick, Mark, Callan, Danielle, Campbell, Lahcen, Christensen, Mikkel B, Christophides, George K, Crouch, Kathryn, Davis, Kristina, DeBarry, Jeremy, Doherty, Ryan, Duan, Yikun, Dunn, Michael, Falke, Dave, Fisher, Steve, Flicek, Paul, Fox, Brett, Gajria, Bindu, Giraldo-Calderón, Gloria I, Harb, Omar S, Harper, Elizabeth, Hertz-Fowler, Christiane, Hickman, Mark J, Howington, Connor, Hu, Sufen, Humphrey, Jay, Iodice, John, Jones, Andrew, Judkins, John, Kelly, Sarah A, Kissinger, Jessica C, Kwon, Dae Kun, Lamoureux, Kristopher, Lawson, Daniel, Li, Wei, Lies, Kallie, Lodha, Disha, Long, Jamie, MacCallum, Robert M, Maslen, Gareth, McDowell, Mary Ann, Nabrzyski, Jaroslaw, Roos, David S, Rund, Samuel S C, Schulman, Stephanie Wever, Shanmugasundram, Achchuthan, Sitnik, Vasily, Spruill, Drew, Starns, David, Stoeckert, Christian J, Tomko, Sheena Shah, Wang, Haiming, Warrenfeltz, Susanne, Wieck, Robert, Wilkinson, Paul A, Xu, Lin, Zheng, Jie
Published in Nucleic acids research

Seasonal shifts in the movement and distribution of green sea turtles Chelonia mydas in response to anthropogenically altered water temperatures

by Crear, Daniel P., Lawson, Daniel D., Seminoff, Jeffrey A., Eguchi, Tomoharu, LeRoux, Robin A., Lowe, Christopher G.
Published in Marine ecology. Progress series (Halstenbek)