Effects of daily L-dopa administration on learning and brain structure in older adults undergoing cognitive training: a randomised clinical trial

by Lebedev, Alexander V, Nilsson, Jonna, Lindström, Joanna, Fredborg, William, Akenine, Ulrika, Hillilä, Carolina, Andersen, Pia, Spulber, Gabriela, de Lange, Elizabeth C M, van den Berg, Dirk-Jan, Kivipelto, Miia, Lövdén, Martin
Published in Scientific reports

Warsaw Breakage Syndrome associated DDX11 helicase resolves G-quadruplex structures to support sister chromatid cohesion

by van Schie, Janne J. M., Faramarz, Atiq, Balk, Jesper A., Stewart, Grant S., Cantelli, Erika, Oostra, Anneke B., Rooimans, Martin A., Parish, Joanna L., de Almeida Estéves, Cynthia, Dumic, Katja, Barisic, Ingeborg, Diderich, Karin E. M., van Slegtenhorst, Marjon A., Mahtab, Mohammad, Pisani, Francesca M., te Riele, Hein, Ameziane, Najim, Wolthuis, Rob M. F., de Lange, Job
Published in Nature communications

The incidence and clinical analysis of non-melanoma skin cancer

by Ciążyńska, Magdalena, Kamińska-Winciorek, Grażyna, Lange, Dariusz, Lewandowski, Bogumił, Reich, Adam, Sławińska, Martyna, Pabianek, Marta, Szczepaniak, Katarzyna, Hankiewicz, Adam, Ułańska, Małgorzata, Morawiec, Jan, Błasińska-Morawiec, Maria, Morawiec, Zbigniew, Piekarski, Janusz, Nejc, Dariusz, Brodowski, Robert, Zaryczańska, Anna, Sobjanek, Michał, Nowicki, Roman J, Owczarek, Witold, Słowińska, Monika, Wróbel, Katarzyna, Bieniek, Andrzej, Woźniacka, Anna, Skibińska, Małgorzata, Narbutt, Joanna, Niemczyk, Wojciech, Ciążyński, Karol, Lesiak, Aleksandra
Published in Scientific reports

Rare and low-frequency coding variants alter human adult height

by Marouli, Eirini, Lo, Ken Sin, Kjaer, Troels R, Rüeger, Sina, Young, Kristin L, Esko, Tõnu, Karaderi, Tugce, Aben, Katja K, Adair, Linda S, Alam, Dewan S, Albrecht, Eva, Auer, Paul L, Bonnycastle, Lori L, Bots, Michiel L, Brandslund, Ivan, Butterworth, Adam S, Chambers, John C, Chen, Yii-Der Ida, Chowdhury, Rajiv, Christensen, Cramer, Chu, Audrey Y, Cook, James P, Cox, Amanda J, Demerath, Ellen W, Drenos, Fotios, Ebeling, Tapani, Ferrario, Marco M, Fornage, Myriam, Galesloot, Tessel E, Gasparini, Paolo, Giri, Ayush, Hayward, Caroline, Hocking, Lynne J, Ikram, M Arfan, Jensen, Gorm B, Jiang, Xuejuan, Kee, Frank, Kitajima, Hidetoshi, Komulainen, Pirjo, Kontto, Jukka, Kuivaniemi, Helena, Laakso, Markku, Lange, Leslie A, Lewis, Cora E, Lind, Lars, Liu, Yeheng, Luan, Jian'an, Lubitz, Steven A, Männistö, Satu, Marten, Jonathan, Mitchell, Paul, Nauck, Matthias, Neville, Matt, Nielsen, Sune F, Nordestgaard, Børge G, Ntalla, Ioanna, Owen, Katharine R, Padmanabhan, Sandosh, Palmer, Colin N A, Patel, Aniruddh P, Perry, James A, Perry, John R B, Polasek, Ozren, Reiner, Alex P, Renström, Frida, Rioux, John D, Rudan, Igor, Sapkota, Yadav, Schreiner, Pamela J, Scott, Robert A, Shah, Svati, Sim, Xueling, Smith, Albert Vernon, Southam, Lorraine, Spector, Timothy D, Thorsteinsdottir, Unnur, Tuomilehto, Jaakko, Tybjaerg-Hansen, Anne, Uitterlinden, André G, Ulivi, Sheila, van Schoor, Natasja M, van Setten, Jessica, Vermeulen, Sita H, Vestergaard, Henrik, Vogt, Thomas F, Vozzi, Diego, Wang, Carol A, Wang, Shuai, Wang, Yiqin, Wareham, Nicholas J, Wu, Ying, Zhan, Xiaowei, Zheng, He, Zhou, Wei, Boehnke, Michael, Borecki, Ingrid B, Kutalik, Zoltán, Frayling, Timothy M, Hirschhorn, Joel N, Deloukas, Panos
Published in Nature (London)

Reducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans

by Sharifi, Samim, Chaudhari, Prerana, Martirosyan, Asya, Eberhardt, Alexander Otto, Witt, Finja, Gollowitzer, André, Lange, Lisa, Woitzat, Yvonne, Okoli, Eberechukwu Maryann, Li, Huahui, Rahnis, Norman, Kirkpatrick, Joanna, Werz, Oliver, Ori, Alessandro, Koeberle, Andreas, Bierhoff, Holger, Ermolaeva, Maria
Published in Nature communications

PTEN as a prognostic and predictive marker in postoperative radiotherapy for squamous cell cancer of the head and neck

by Snietura, Miroslaw, Jaworska, Magdalena, Mlynarczyk-Liszka, Joanna, Goraj-Zajac, Aleksandra, Piglowski, Wojciech, Lange, Dariusz, Wozniak, Grzegorz, Nowara, Elzbieta, Suwinski, Rafal
Published in PloS one

Role of glutamine synthetase in angiogenesis beyond glutamine synthesis

by Eelen, Guy, Dubois, Charlotte, Cantelmo, Anna Rita, Goveia, Jermaine, Brüning, Ulrike, DeRan, Michael, Jarugumilli, Gopala, van Rijssel, Jos, Saladino, Giorgio, Comitani, Federico, Zecchin, Annalisa, Rocha, Susana, Chen, Rongyuan, Huang, Hongling, Vandekeere, Saar, Kalucka, Joanna, Lange, Christian, Morales-Rodriguez, Francisco, Cruys, Bert, Treps, Lucas, Ramer, Leanne, Vinckier, Stefan, Brepoels, Katleen, Wyns, Sabine, Souffreau, Joris, Schoonjans, Luc, Lamers, Wouter H, Wu, Yi, Haustraete, Jurgen, Hofkens, Johan, Liekens, Sandra, Cubbon, Richard, Ghesquière, Bart, Dewerchin, Mieke, Gervasio, Francesco L, Li, Xuri, van Buul, Jaap D, Wu, Xu, Carmeliet, Peter
Published in Nature (London)

Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal

by Maji, Arun, Soutar, Corinne P, Zhang, Jiabao, Lewandowska, Agnieszka, Uno, Brice E, Yan, Su, Shelke, Yogesh, Murhade, Ganesh, Nimerovsky, Evgeny, Borcik, Collin G, Arango, Andres S, Lange, Justin D, Marin-Toledo, Jonnathan P, Lyu, Yinghuan, Bailey, Keith L, Roady, Patrick J, Holler, Jordan T, Khandelwal, Anuj, SantaMaria, Anna M, Sanchez, Hiram, Juvvadi, Praveen R, Johns, Gina, Hageman, Michael J, Krise, Joanna, Gebremariam, Teclegiorgis, Youssef, Eman G, Bartizal, Ken, Marr, Kieren A, Steinbach, William J, Ibrahim, Ashraf S, Patterson, Thomas F, Wiederhold, Nathan P, Andes, David R, Pogorelov, Taras V, Schwieters, Charles D, Fan, Timothy M, Rienstra, Chad M, Burke, Martin D
Published in Nature (London)

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

by Giambartolomei, Claudia, de Vries, Paul S, Huntley, Rachael P, Lovering, Ruth C, Winkler, Thomas W, Graff, Misa, Kavousi, Maryam, Dale, Caroline, Smith, Albert V, Hofer, Edith, Nolte, Ilja M, Lu, Lingyi, Scholz, Markus, Sargurupremraj, Muralidharan, Pitkänen, Niina, Marioni, Riccardo E, Musani, Solomon K, Schminke, Ulf, Palmas, Walter, Isaacs, Aaron, Correa, Adolfo, Teumer, Alexander, Uitterlinden, André G, Wong, Andrew, Newman, Anne B, Britton, Annie, Ruusalepp, Arno, Sennblad, Bengt, Hedblad, Bo, Langefeld, Carl D, Wassel, Christina L, Fava, Cristiano, O'Leary, Daniel H, Teupser, Daniel, Kuh, Diana, Tremoli, Elena, Boerwinkle, Eric, Schadt, Eric E, Rivadeneira, Fernando, Beutner, Frank, Chauhan, Ganesh, Snieder, Harold, Campbell, Harry, Markus, Hugh S, Jukema, J Wouter, Hopewell, Jemma C, Thiery, Joachim, Rice, Kenneth, Dhana, Klodian, Lind, Lars, Raffield, Laura M, Launer, Lenore J, Holdt, Lesca M, Dichgans, Martin, Traylor, Matthew, Sitzer, Matthias, Kumari, Meena, Melander, Olle, Raitakari, Olli, Franco, Oscar H, Rueda-Ochoa, Oscar L, Roussos, Panos, Whincup, Peter H, Giral, Philippe, Anugu, Pramod, Malik, Rainer, Rauramaa, Rainer, Hardy, Rebecca, Schmidt, Reinhold, Strawbridge, Rona J, Shah, Sonia, McLachlan, Stela, Trompet, Stella, Ring, Susan, Harris, Tamara B, Galesloot, Tessel E, Plagnol, Vincent, Rosamond, Wayne D, Post, Wendy, Zhu, Xiaofeng, Zhang, Xiaoling, Guo, Xiuqing, Saba, Yasaman, Seldenrijk, Adrie, Hamsten, Anders, Mook-Kanamori, Dennis O, Bowden, Donald W, Schmidt, Helena, Wilson, James F, Wilson, James G, Deanfield, John, Halcox, Julian, Lyytikäinen, Leo-Pekka, Loeffler, Markus, Evans, Michele K, Debette, Stéphanie, Völker, Uwe, Gudnason, Vilmundur, Casas, Juan P, O'Donnell, Christopher J
Published in Nature communications

Clinical and epidemiological analysis of basosquamous carcinoma: results of the multicenter study

by Ciążyńska, Magdalena, Sławińska, Martyna, Kamińska-Winciorek, Grażyna, Lange, Dariusz, Lewandowski, Bogumił, Reich, Adam, Pabianek, Marta, Szczepaniak, Katarzyna, Hankiewicz, Adam, Ułańska, Małgorzata, Morawiec, Jan, Błasińska-Morawiec, Maria, Morawiec, Zbigniew, Piekarski, Janusz, Brodowski, Robert, Zaryczańska, Anna, Sobjanek, Michał, Owczarek, Witold, Słowińska, Monika, Wróbel, Katarzyna, Bieniek, Andrzej, Woźniacka, Anna, Skibińska, Małgorzata, Narbutt, Joanna, Niemczyk, Wojciech, Ciążyński, Karol, Lesiak, Aleksandra
Published in Scientific reports

Genetic determinants of micronucleus formation in vivo

by Adams, D J, Barlas, B, McIntyre, R E, Salguero, I, van der Weyden, L, Barros, A, Vicente, J R, Karimpour, N, Haider, A, Ranzani, M, Turner, G, Thompson, N A, Harle, V, Olvera-León, R, Robles-Espinoza, C D, Speak, A O, Geisler, N, Weninger, W J, Geyer, S H, Hewinson, J, Karp, N A, Fu, B, Yang, F, Kozik, Z, Choudhary, J, Yu, L, van Ruiten, M S, Rowland, B D, Lelliott, C J, Del Castillo Velasco-Herrera, M, Verstraten, R, Bruckner, L, Henssen, A G, Rooimans, M A, de Lange, J, Mohun, T J, Arends, M J, Kentistou, K A, Coelho, P A, Zhao, Y, Zecchini, H, Perry, J R B, Jackson, S P, Balmus, G
Published in Nature (London)

Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosis

by Krebs, Kristi, Graham, Sarah, Mishra, Binisha H., Lehtimäki, Terho, Esko, Tõnu, Metspalu, Andres, Nelis, Mari, Milani, Lili, Morisaki, Takayuki, Kamatani, Yoichiro, Takahashi, Kazuhisa, Sinozaki, Nobuaki, Yamaguchi, Hiroki, Minami, Shiro, Obata, Daisuke, Paul, Dirk, Runz, Heiko, Klinger, Katherine, Mäkelä, Tomi, Virolainen, Petri, Hakanen, Antti, Partanen, Jukka, Kosma, Veli-Matti, Abbasi, Ali, Liu, Mengzhen, Tachmazidou, Ioanna, Gossel, Matthias, Schleutker, Johanna, Soininen, Hilkka, Esmaeeli, Sahar, Lehtonen, Anne, Pendergrass, Sarah, Linden, Kari, Usiskin, Keith, Kalpala, Kirsi, Miller, Melissa, McCarthy, Linda, Pirilä, Laura, Kaipiainen-Seppänen, Oili, Huhtakangas, Johanna, Lertratanakul, Apinya, Bing, Nan, Gordillo, Jorge Esparza, Harju, Terttu, Lahesmaa, Riitta, Niiranen, Teemu, Salomaa, Veikko, Laakso, Markku, Taskinen, Marja-Riitta, Tuomi, Tiinamaija, Elliott, Amanda, Joensuu, Heikki, Karihtala, Peeter, Schutzman, Jennifer, Loboda, Andrey, Lehtonen, Heli, McDonough, Stefan, Pitkänen, Esa, Kaarniranta, Kai, Turunen, Joni A., Ollila, Terhi, Podgornaia, Anna, Peltonen, Sirkku, Koulu, Leena, Rice, David, Palotie, Ulla, Gursoy, Ulvi, Sipilä, Kirsi, Vääräsmäki, Marja, Välimäki, Niko, Petrovski, Slavé, Sun, Benjamin, Huang, Yunfeng, Mohammed, Elmutaz, Kvikstad, Erika, Caliskan, Minal, Neduva, Victor, Chen, Xing, Hedman, Åsa, Xia, Tai-He, Cole, Amy, Chung, Jonathan, de Lange, Katrina, Mehtonen, Juha, Palta, Priit, Niemi, Mari E., Kiiskinen, Tuomo, Kalaoja, Marita, Karjalainen, Minna, Kallio, Lila, Aavikko, Mervi, Lahtela, L. Elisa, Kaunisto, Mari, Ghazal, Awaisa, Koskelainen, Sami, Luo, Shuang, Sinha, Vishal, Hautalahti, Marco, Mustaniemi, Laura, Koivusalo, Mirkka
Published in Communications biology

Consent for Brain Tissue Donation after Intracerebral Haemorrhage: A Community-Based Study

by Samarasekera, Neshika, Lerpiniere, Christine, Fonville, Arthur F, Farrall, Andrew J, Wardlaw, Joanna M, White, Philip M, Torgersen, Antonia, Ironside, James W, Smith, Colin, Al-Shahi Salman, Rustam
Published in PloS one