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A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects
by
Talukdar, Saswata
,
Zhou, Yingjiang
,
Li, Dongmei
,
Rossulek, Michelle
,
Dong, Jennifer
,
Somayaji, Veena
,
Weng, Yan
,
Clark, Ronald
,
Lanba, Adhiraj
,
Owen, Bryn M.
,
Brenner, Martin B.
,
Trimmer, Jeffrey K.
,
Gropp, Kathryn E.
,
Chabot, Jeffrey R.
,
Erion, Derek M.
,
Rolph, Timothy P.
,
Goodwin, Bryan
,
Calle, Roberto A.
Published in
Cell metabolism
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Inhibition of Acetyl-CoA Carboxylase 1 (ACC1) and 2 (ACC2) Reduces Proliferation and De Novo Lipogenesis of EGFRvIII Human Glioblastoma Cells
by
Jones, Jessica E C
,
Esler, William P
,
Patel, Rushi
,
Lanba, Adhiraj
,
Vera, Nicholas B
,
Pfefferkorn, Jeffrey A
,
Vernochet, Cecile
Published in
PloS one
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Inhibition of Acetyl-CoA Carboxylase 1 Reduces Proliferation and De Novo Lipogenesis of EGFRvIII Human Glioblastoma Cells
by
Jones, Jessica E. C
,
Esler, William P
,
Patel, Rushi
,
Lanba, Adhiraj
,
Vera, Nicholas B
,
Pfefferkorn, Jeffrey A
,
Vernochet, Cecile
Published in
PloS one
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Inhibition of Acetyl-CoA Carboxylase 1
by
Jones, Jessica E. C
,
Esler, William P
,
Patel, Rushi
,
Lanba, Adhiraj
,
Vera, Nicholas B
,
Pfefferkorn, Jeffrey A
,
Vernochet, Cecile
Published in
PloS one
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Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5)
by
Huard, Kim
,
Brown, Janice
,
Jones, Jessica C
,
Cabral, Shawn
,
Futatsugi, Kentaro
,
Gorgoglione, Matthew
,
Lanba, Adhiraj
,
Vera, Nicholas B
,
Zhu, Yimin
,
Yan, Qingyun
,
Zhou, Yingjiang
,
Vernochet, Cecile
,
Riccardi, Keith
,
Wolford, Angela
,
Pirman, David
,
Niosi, Mark
,
Aspnes, Gary
,
Herr, Michael
,
Genung, Nathan E
,
Magee, Thomas V
,
Uccello, Daniel P
,
Loria, Paula
,
Di, Li
,
Gosset, James R
,
Hepworth, David
,
Rolph, Timothy
,
Pfefferkorn, Jeffrey A
,
Erion, Derek M
Published in
Scientific reports
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Optimization of a Dicarboxylic Series for in Vivo Inhibition of Citrate Transport by the Solute Carrier 13 (SLC13) Family
by
Huard, Kim
,
Gosset, James R
,
Montgomery, Justin I
,
Gilbert, Adam
,
Hayward, Matthew M
,
Magee, Thomas V
,
Cabral, Shawn
,
Uccello, Daniel P
,
Bahnck, Kevin
,
Brown, Janice
,
Purkal, Julie
,
Gorgoglione, Matthew
,
Lanba, Adhiraj
,
Futatsugi, Kentaro
,
Herr, Michael
,
Genung, Nathan E
,
Aspnes, Gary
,
Polivkova, Jana
,
Garcia-Irizarry, Carmen N
,
Li, Qifang
,
Canterbury, Daniel
,
Niosi, Mark
,
Vera, Nicholas B
,
Li, Zhenhong
,
Khunte, Bhagyashree
,
Siderewicz, Jaclyn
,
Rolph, Timothy
,
Erion, Derek M
Published in
Journal of medicinal chemistry
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Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism
by
Ahn, Kay
,
Boehm, Markus
,
Brown, Matthew F
,
Calloway, Jessica
,
Che, Ye
,
Chen, Jinshan
,
Fennell, Kimberly F
,
Geoghegan, Kieran F
,
Gilbert, Adam M
,
Gutierrez, Jemy A
,
Kalgutkar, Amit S
,
Lanba, Adhiraj
,
Limberakis, Chris
,
Magee, Thomas V
,
O’Doherty, Inish
,
Oliver, Robert
,
Pabst, Brandon
,
Pandit, Jayvardhan
,
Parris, Kevin
,
Pfefferkorn, Jeffrey A
,
Rolph, Timothy P
,
Patel, Rushi
,
Schuff, Brandon
,
Shanmugasundaram, Veerabahu
,
Starr, Jeremy T
,
Varghese, Alison H
,
Vera, Nicholas B
,
Vernochet, Cecile
,
Yan, Jiangli
Published in
ACS chemical biology
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