Targeting loss of the Hippo signaling pathway in NF2 -deficient papillary kidney cancers

by Sourbier, Carole, Liao, Pei-Jyun, Ricketts, Christopher J, Wei, Darmood, Yang, Youfeng, Baranes, Sarah M, Gibbs, Benjamin K, Ohanjanian, Lernik, Spencer Krane, L, Scroggins, Bradley T, Keith Killian, J, Wei, Ming-Hui, Kijima, Toshiki, Meltzer, Paul S, Citrin, Deborah E, Neckers, Len, Vocke, Cathy D, Marston Linehan, W
Published in Oncotarget

Patient-specific factors influence somatic variation patterns in von Hippel-Lindau disease renal tumours

by Fei, Suzanne S, Mitchell, Asia D, Heskett, Michael B, Vocke, Cathy D, Ricketts, Christopher J, Peto, Myron, Wang, Nicholas J, Sönmez, Kemal, Linehan, W Marston, Spellman, Paul T
Published in Nature communications

Robot-assisted laparoscopic partial nephrectomy for tumors greater than 4 cm and high nephrometry score: Feasibility, renal functional, and oncological outcomes with minimum 1 year...

by Gupta, Gopal N., M.D, Boris, Ronald, M.D, Chung, Paul, B.S, Linehan, W. Marston, M.D, Pinto, Peter A., M.D, Bratslavsky, Gennady, M.D
Published in Urologic oncology

Loss of Folliculin Disrupts Hematopoietic Stem Cell Quiescence and Homeostasis Resulting in Bone Marrow Failure

by Baba, Masaya, Toyama, Hirofumi, Sun, Lei, Takubo, Keiyo, Suh, Hyung‐Chan, Hasumi, Hisashi, Nakamura‐Ishizu, Ayako, Hasumi, Yukiko, Klarmann, Kimberly D., Nakagata, Naomi, Schmidt, Laura S., Linehan, W. Marston, Suda, Toshio, Keller, Jonathan R.
Published in Stem cells (Dayton, Ohio)

High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma

by Lang, Martin, Schmidt, Laura S, Wilson, Kelli M, Ricketts, Christopher J, Sourbier, Carole, Vocke, Cathy D, Wei, Darmood, Crooks, Daniel R, Yang, Youfeng, Gibbs, Benjamin K, Zhang, Xiaohu, Klumpp-Thomas, Carleen, Chen, Lu, Guha, Rajarshi, Ferrer, Marc, McKnight, Crystal, Itkin, Zina, Wangsa, Darawalee, Wangsa, Danny, James, Amy, Difilippantonio, Simone, Karim, Baktir, Morís, Francisco, Ried, Thomas, Merino, Maria J, Srinivasan, Ramaprasad, Thomas, Craig J, Linehan, W Marston
Published in Journal of experimental & clinical cancer research

Use of Patient-specific MRI-based Prostate Mold for Validation of Multiparametric MRI in Localization of Prostate Cancer

by Trivedi, Hari, Turkbey, Baris, Rastinehad, Ardeshir R, Benjamin, Compton J, Bernardo, Marcelino, Pohida, Thomas, Shah, Vijay, Merino, Maria J, Wood, Bradford J, Linehan, W. Marston, Venkatesan, Aradhana M, Choyke, Peter L, Pinto, Peter A
Published in Urology (Ridgewood, N.J.)

Pseudohypoxic Pathways in Renal Cell Carcinoma

by BRATSLAVSKY, Gennady, SUDARSHAN, Sunil, NECKERS, Len, LINEHAN, W. Marston
Published in Clinical cancer research

New insights into von Hippel-Lindau function highlighted by investigation of the trichloroethylene-induced p.P81S hotspot mutation

by Neckers, Len, Ricketts, Christopher J, Marston Linehan, W
Published in JNCI : Journal of the National Cancer Institute

Primary neuroendocrine tumors of the kidney: morphological and molecular alterations of an uncommon malignancy

by Aung, Phyu P., MD, PhD, Killian, Keith, MD, PhD, Poropatich, Carrie O., MD, Linehan, W. Marston, MD, Merino, Maria J., MD
Published in Human pathology

H255Y and K508R missense mutations in tumour suppressor folliculin (FLCN) promote kidney cell proliferation

by Hasumi, Hisashi, Hasumi, Yukiko, Baba, Masaya, Nishi, Hafumi, Furuya, Mitsuko, Vocke, Cathy D, Lang, Martin, Irie, Nobuko, Esumi, Chiharu, Merino, Maria J, Kawahara, Takashi, Isono, Yasuhiro, Makiyama, Kazuhide, Warner, Andrew C, Haines, Diana C, Wei, Ming-Hui, Zbar, Berton, Hagenau, Herbert, Feigenbaum, Lionel, Kondo, Keiichi, Nakaigawa, Noboru, Yao, Masahiro, Metwalli, Adam R, Marston Linehan, W, Schmidt, Laura S
Published in Human molecular genetics

Age at Diagnosis of Pheochromocytoma Differs According to Catecholamine Phenotype and Tumor Location

by Eisenhofer, Graeme, Timmers, Henri J, Lenders, Jacques W.M, Bornstein, Stefan R, Tiebel, Oliver, Mannelli, Massimo, King, Kathryn S, Vocke, Cathy D, Linehan, W. Marston, Bratslavsky, Gennady, Pacak, Karel
Published in The journal of clinical endocrinology and metabolism

18Fluorodeoxyglucose-positron emission tomography/computed tomography for differentiation of renal tumors in hereditary kidney cancer syndromes

by Nikpanah, Moozhan, Paschall, Anna K., Ahlman, Mark A., Civelek, Ali Cahid, Farhadi, Faraz, Mirmomen, S. Mojdeh, Li, Xiaobai, Saboury, Babak, Ball, Mark W., Merino, Maria J., Srinivasan, Ramaprasad, Jones, Elizabeth C., Linehan, W. Marston, Malayeri, Ashkan A.
Published in Abdominal radiology (New York)

Targeting mutant p53-R248W reactivates WT p53 function and alters the onco-metabolic profile

by Brown, Kate, Jenkins, Lisa M Miller, Crooks, Daniel R, Surman, Deborah R, Mazur, Sharlyn J, Xu, Yuan, Arimilli, Bhargav S, Yang, Ye, Lane, Andrew N, Fan, Teresa W-M, Schrump, David S, Linehan, W Marston, Ripley, R Taylor, Appella, Ettore
Published in Frontiers in oncology

Seventh BHD international symposium: recent scientific and clinical advancement

by Woodford, Mark R, Andreou, Avgi, Baba, Masaya, van de Beek, Irma, Di Malta, Chiara, Glykofridis, Iris, Grimes, Hannah, Henske, Elizabeth P, Iliopoulos, Othon, Kurihara, Masatoshi, Lazor, Romain, Linehan, W Marston, Matsumoto, Kenki, Marciniak, Stefan J, Namba, Yukiko, Pause, Arnim, Rajan, Neil, Ray, Anindita, Schmidt, Laura S, Shi, Wei, Steinlein, Ortrud K, Thierauf, Julia, Zoncu, Roberto, Webb, Anna, Mollapour, Mehdi
Published in Oncotarget

Impact of Ischemia and Procurement Conditions on Gene Expression in Renal Cell Carcinoma

by LIU, Nick W, SANFORD, Thomas, YOUFENG YANG, MERINO, Maria, MARSTON LINEHAN, W, BRATSLAVSKY, Gennady, SRINIVASAN, Ramaprasad, LIU, Jack L, KHURANA, Kiranpreet, APRELIKOVA, Olga, VALERO, Vladimir, BECHERT, Charles, WORRELL, Robert, PINTO, Peter A
Published in Clinical cancer research

Imaging of glucose metabolism by 13C-MRI distinguishes pancreatic cancer subtypes in mice

by Kishimoto, Shun, Brender, Jeffrey R, Crooks, Daniel R, Matsumoto, Shingo, Seki, Tomohiro, Oshima, Nobu, Merkle, Hellmut, Lin, Penghui, Reed, Galen, Chen, Albert P, Ardenkjaer-Larsen, Jan Henrik, Munasinghe, Jeeva, Saito, Keita, Yamamoto, Kazutoshi, Choyke, Peter L, Mitchell, James, Lane, Andrew N, Fan, Teresa Wm, Linehan, W Marston, Krishna, Murali C
Published in eLife

Mutations in the Fumarate Hydratase Gene Cause Hereditary Leiomyomatosis and Renal Cell Cancer in Families in North America

by Toro, Jorge R., Nickerson, Michael L., Wei, Ming-Hui, Warren, Michelle B., Glenn, Gladys M., Turner, Maria L., Stewart, Laveta, Duray, Paul, Tourre, Ousman, Sharma, Nirmala, Choyke, Peter, Stratton, Pamela, Merino, Maria, Walther, McClellan M., Linehan, W. Marston, Schmidt, Laura S., Zbar, Berton
Published in American journal of human genetics

Oncogenic MITF dysregulation in clear cell sarcoma: Defining the MiT family of human cancers

by Davis, Ian J., Kim, Jessica J., Ozsolak, Fatih, Widlund, Hans R., Rozenblatt-Rosen, Orit, Granter, Scott R., Du, Jinyan, Fletcher, Jonathan A., Denny, Christopher T., Lessnick, Stephen L., Linehan, W. Marston, Kung, Andrew L., Fisher, David E.
Published in Cancer cell

The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development

by Baba, Masaya, Keller, Jonathan R., Sun, Hong-Wei, Resch, Wolfgang, Kuchen, Stefan, Suh, Hyung Chan, Hasumi, Hisashi, Hasumi, Yukiko, Kieffer-Kwon, Kyong-Rim, Gonzalez, Carme Gallego, Hughes, Robert M., Klein, Mara E., Oh, Hyoungbin F., Bible, Paul, Southon, Eileen, Tessarollo, Lino, Schmidt, Laura S., Linehan, W. Marston, Casellas, Rafael
Published in Blood

Identification of the Genes for Kidney Cancer: Opportunity for Disease-Specific Targeted Therapeutics

by Linehan, W Marston, Pinto, Peter A, Srinivasan, Ramaprasad, Merino, Maria, Choyke, Peter, Choyke, Lynda, Coleman, Jonathan, Toro, Jorge, Glenn, Gladys, Vocke, Cathy, Zbar, Bert, Schmidt, Laura S, Bottaro, Donald, Neckers, Len
Published in Clinical cancer research