Severe anemia in Malawian children

by Calis, Job Cj, Phiri, Kamija S, Faragher, E Brian, Brabin, Bernard J, Bates, Imelda, Cuevas, Luis E, de Haan, Rob J, Phiri, Ajib I, Malange, Pelani, Khoka, Mirriam, Hulshof, Paul Jm, van Lieshout, Lisette, Beld, Marcel Ghm, Teo, Yik Y, Rockett, Kirk A, Richardson, Anna, Kwiatkowski, Dominic P, Molyneux, Malcolm E, van Hensbroek, Michaël Boele
Published in Malawi medical journal

Evolutionary analysis of the most polymorphic gene family in falciparum malaria

by Otto, Thomas D, Assefa, Sammy A, Böhme, Ulrike, Sanders, Mandy J, Kwiatkowski, Dominic, Berriman, Matt, Newbold, Chris
Published in Wellcome open research

Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya

by Borrmann, Steffen, Straimer, Judith, Mwai, Leah, Abdi, Abdirahman, Rippert, Anja, Okombo, John, Muriithi, Steven, Sasi, Philip, Kortok, Moses Mosobo, Lowe, Brett, Campino, Susana, Assefa, Samuel, Auburn, Sarah, Manske, Magnus, Maslen, Gareth, Peshu, Norbert, Kwiatkowski, Dominic P, Marsh, Kevin, Nzila, Alexis, Clark, Taane G
Published in Scientific reports

Genome-wide association studies reveal novel loci associated with pyrethroid and organophosphate resistance in Anopheles gambiae and Anopheles coluzzii

by Lucas, Eric R, Nagi, Sanjay C, Egyir-Yawson, Alexander, Essandoh, John, Dadzie, Samuel, Chabi, Joseph, Djogbénou, Luc S, Medjigbodo, Adandé A, Edi, Constant V, Kétoh, Guillaume K, Koudou, Benjamin G, Van't Hof, Arjen E, Rippon, Emily J, Pipini, Dimitra, Harding, Nicholas J, Dyer, Naomi A, Cerdeira, Louise T, Clarkson, Chris S, Kwiatkowski, Dominic P, Miles, Alistair, Donnelly, Martin J, Weetman, David
Published in Nature communications

Haplotypic analysis of the TNF locus by association efficiency and entropy

by Ackerman, Hans, Usen, Stanley, Mott, Richard, Richardson, Anna, Sisay-Joof, Fatoumatta, Katundu, Pauline, Taylor, Terrie, Ward, Ryk, Molyneux, Malcolm, Pinder, Margaret, Kwiatkowski, Dominic P
Published in Genome biology

Comparison of genomic signatures of selection on Plasmodium falciparum between different regions of a country with high malaria endemicity

by Duffy, Craig W, Assefa, Samuel A, Abugri, James, Amoako, Nicholas, Owusu-Agyei, Seth, Anyorigiya, Thomas, MacInnis, Bronwyn, Kwiatkowski, Dominic P, Conway, David J, Awandare, Gordon A
Published in BMC genomics

Haplotype mapping of the bronchiolitis susceptibility locus near IL8

by HULL, Jeremy, ROWLANDS, Kate, LOCKHART, Elizabeth, SHARLAND, Mike, MOORE, Catrin, HANCHARD, Neil, KWIATKOWSKI, Dominic P
Published in Human genetics

Environmental Correlation Analysis for Genes Associated with Protection against Malaria

by Mackinnon, Margaret J, Ndila, Carolyne, Uyoga, Sophie, Macharia, Alex, Snow, Robert W, Band, Gavin, Rautanen, Anna, Rockett, Kirk A, Kwiatkowski, Dominic P, Williams, Thomas N
Published in Molecular biology and evolution

Monitoring parasite diversity for malaria elimination in sub-Saharan Africa

by Ghansah, Anita, Amenga-Etego, Lucas, Amambua-Ngwa, Alfred, Andagalu, Ben, Apinjoh, Tobias, Bouyou-Akotet, Marielle, Cornelius, Victoria, Golassa, Lemu, Andrianaranjaka, Voahangy Hanitriniaina, Ishengoma, Deus, Johnson, Kimberly, Kamau, Edwin, Maïga-Ascofaré, Oumou, Mumba, Dieudonne, Tindana, Paulina, Tshefu-Kitoto, Antoinette, Randrianarivelojosia, Milijaona, William, Yavo, Kwiatkowski, Dominic P., Djimde, Abdoulaye A.
Published in Science (American Association for the Advancement of Science)

A coding polymorphism in matrix metalloproteinase 9 reduces risk of scarring sequelae of ocular Chlamydia trachomatis infection

by Natividad, Angels, Cooke, Graham, Holland, Martin J, Burton, Matthew J, Joof, Hassan M, Rockett, Kirk, Kwiatkowski, Dominic P, Mabey, David C W, Bailey, Robin L
Published in BMC medical genetics

Whole-Genome Scans Provide Evidence of Adaptive Evolution in Malawian Plasmodium falciparum Isolates

by Ocholla, Harold, Preston, Mark D., Mipando, Mwapatsa, Jensen, Anja T. R., Campino, Susana, MacInnis, Bronwyn, Alcock, Daniel, Terlouw, Anja, Zongo, Issaka, Oudraogo, Jean-Bosco, Djimde, Abdoulaye A., Assefa, Samuel, Doumbo, Ogobara K., Borrmann, Steffen, Nzila, Alexis, Marsh, Kevin, Fairhurst, Rick M., Nosten, Francois, Anderson, Tim J. C, Kwiatkowski, Dominic P., Craig, Alister, Clark, Taane G., Montgomery, Jacqui
Published in The Journal of infectious diseases

Massive introgression drives species radiation at the range limit of Anopheles gambiae

by Vicente, José L, Clarkson, Christopher S, Caputo, Beniamino, Gomes, Bruno, Pombi, Marco, Sousa, Carla A, Antao, Tiago, Dinis, João, Bottà, Giordano, Mancini, Emiliano, Petrarca, Vincenzo, Mead, Daniel, Drury, Eleanor, Stalker, James, Miles, Alistair, Kwiatkowski, Dominic P, Donnelly, Martin J, Rodrigues, Amabélia, Torre, Alessandra Della, Weetman, David, Pinto, João
Published in Scientific reports

Nucleotide and haplotypic diversity of the NOS2A promoter region and its relationship to cerebral malaria

by BURGNER, David, USEN, Stanley, ROCKETT, Kirk, JALLOW, Muminatou, ACKERMAN, Hans, CERVINO, Alessandra, PINDER, Margaret, KWIATKOWSKI, Dominic P
Published in Human genetics

Genomic variation during culture adaptation of genetically complex Plasmodium falciparum clinical isolates

by Claessens, Antoine, Stewart, Lindsay B, Drury, Eleanor, Ahouidi, Ambroise D, Amambua-Ngwa, Alfred, Diakite, Mahamadou, Kwiatkowski, Dominic P, Awandare, Gordon A, Conway, David J
Published in Microbial genomics

Lack of association of interferon regulatory factor 1 with severe malaria in affected child-parental trio studies across three African populations

by Mangano, Valentina D, Clark, Taane G, Auburn, Sarah, Campino, Susana, Diakite, Mahamadou, Fry, Andrew E, Green, Angela, Richardson, Anna, Jallow, Muminatou, Sisay-Joof, Fatou, Pinder, Margaret, Griffiths, Michael J, Newton, Charles, Peshu, Norbert, Williams, Thomas N, Marsh, Kevin, Molyneux, Malcolm E, Taylor, Terrie E, Modiano, David, Kwiatkowski, Dominic P, Rockett, Kirk A
Published in PloS one

Changes in Malaria Parasite Drug Resistance in an Endemic Population Over a 25-Year Period With Resulting Genomic Evidence of Selection

by Nwakanma, Davis C., Duffy, Craig W., Amambua-Ngwa, Alfred, Oriero, Eniyou C., Bojang, Kalifa A., Pinder, Margaret, Drakeley, Chris J., Sutherland, Colin J., Milligan, Paul J., MacInnis, Bronwyn, Kwiatkowski, Dominic P., Clark, Taane G., Greenwood, Brian M., Conway, David J.
Published in The Journal of infectious diseases

Common variation in the ABO glycosyltransferase is associated with susceptibility to severe Plasmodium falciparum malaria

by Fry, Andrew E., Griffiths, Michael J., Auburn, Sarah, Diakite, Mahamadou, Forton, Julian T., Green, Angela, Richardson, Anna, Wilson, Jonathan, Jallow, Muminatou, Sisay-Joof, Fatou, Pinder, Margaret, Peshu, Norbert, Williams, Thomas N., Marsh, Kevin, Molyneux, Malcolm E., Taylor, Terrie E., Rockett, Kirk A., Kwiatkowski, Dominic P.
Published in Human molecular genetics

Heterogeneous alleles comprising G6PD deficiency trait in West Africa exert contrasting effects on two major clinical presentations of severe malaria

by Shah, Shivang S, Rockett, Kirk A, Jallow, Muminatou, Sisay-Joof, Fatou, Bojang, Kalifa A, Pinder, Margaret, Jeffreys, Anna, Craik, Rachel, Hubbart, Christina, Wellems, Thomas E, Kwiatkowski, Dominic P
Published in Malaria journal

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

by Ahouidi, Ambroise, Ali, Mozam, Almagro-Garcia, Jacob, Amambua-Ngwa, Alfred, Amaratunga, Chanaki, Amenga-Etego, Lucas, Andagalu, Ben, Anderson, Tim J. C., Andrianaranjaka, Voahangy, Ariani, Cristina, Ashley, Elizabeth A., Auburn, Sarah, Baraka, Vito, Bejon, Philip, Boni, Maciej F., Bousema, Teun, Bull, Peter C., Busby, George B. J., Chookajorn, Thanat, Chotivanich, Kesinee, Claessens, Antoine, Conway, David, Craig, Alister, Dama, Souleymane, Day, Nicholas P.J., Diakite, Mahamadou, Dolecek, Christiane, Dondorp, Arjen M., Drakeley, Chris, Drury, Eleanor, Duffy, Patrick, Echeverry, Diego F., Egwang, Thomas G., Fairhurst, Rick M., Faiz, Abdul, Gamboa, Dionicia, Hamilton, William L., Harrison, G. L. Abby, Hart, Lee, Henrichs, Christa, Hill, Catherine A., Hodgson, Abraham, Hubbart, Christina, Imwong, Mallika, Ishengoma, Deus S., Jackson, Scott A., Jacob, Chris G., Jeffery, Ben, Jeffreys, Anna E., Johnson, Kimberly J., Jyothi, Dushyanth, Kamaliddin, Claire, Kamau, Edwin, Kekre, Mihir, Kluczynski, Krzysztof, Konaté, Abibatou, Lim, Pharath, Malangone, Cinzia, Manske, Magnus, Mayxay, Mayfong, Miles, Alistair, Mobegi, Victor, Mokuolu, Olugbenga A., Montgomery, Jacqui, Mueller, Ivo, Newton, Paul N., Nguyen, Thuy, Nosten, François, Noviyanti, Rintis, Nzila, Alexis, Ochola-Oyier, Lynette I., Ocholla, Harold, Oduro, Abraham, Omedo, Irene, Ouedraogo, Jean-Bosco, Oyebola, Kolapo, Pearson, Richard D., Phyo, Aung Pyae, Price, Ric N., Pukrittayakamee, Sasithon, Randrianarivelojosia, Milijaona, Rayner, Julian C., Ringwald, Pascal, Rockett, Kirk A., Rowlands, Katherine, Ruiz, Lastenia, Saunders, David, Siba, Peter, Simpson, Victoria J., Su, Xin-zhuan, Takala-Harrison, Shannon, Tavul, Livingstone, Thathy, Vandana, Tshefu, Antoinette, Verra, Federica, Vinetz, Joseph, White, Nicholas J., Wright, Ian, Yavo, William, Ye, Htut
Published in Wellcome open research

Genomic variation in two gametocyte non-producing Plasmodium falciparum clonal lines

by Campino, Susana, Benavente, Ernest Diez, Assefa, Samuel, Thompson, Eloise, Drought, Laura G, Taylor, Catherine J, Gorvett, Zaria, Carret, Celine K, Flueck, Christian, Ivens, Al C, Kwiatkowski, Dominic P, Alano, Pietro, Baker, David A, Clark, Taane G
Published in Malaria journal