Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity

by Shepherd, James, Koshy, Cherian, Wise, Emma, Curran, Tanya, Adams, Helen, Moore, Catrin, Khokhar, Fahad A., Reynolds, Nicola, Afifi, Safiah, Price, Anna, Kitchen, Christine, Merrick, Ian, Connor, Thomas R., Bresner, Catherine, Robson, Samuel C., Menegazzo, Mirko, Clark, Gemma, Fleming, Vicki M., Howson-Wells, Hannah C., Bird, Paul, Helmer, Thomas, Fallon, Karlie, du Plessis, Louis, Attwood, Stephen, Vasylyeva, Tetyana, Chaudhry, Yasmin, Moses, Samuel, Ryan, Felicity, Brown, Julianne Rose, Lee, Jack C.D., Alcolea-Medina, Adela, Moore, Nathan, Cortes, Nicholas, Williams, Rebecca, Smith, Darren L., Holmes, Alison, Price, James, Rowan, Aileen, Taylor, Graham P., Watts, Joanne, Ludden, Catherine, George, Ryan P., Li, Kathy K., Carmichael, Stephen N., Johnson, Natasha, Orton, Richard J., Hale, Antony D., Harper, Katherine L., Eltringham, Gary, Coupland, Lindsay J., Barton, Edward, Scott, Garren, Yew, Wen C., Resende Silva, Paola C., Justice, Anita, Chand, Meera, Williams, David, Harrison, Ian, Chalker, Vicki, Heyburn, David, Downing, Fatima, Watkins, Joanne, Howe, Robin, Taylor, Sarah, Wain, John, Rudder, Steven, Gilroy, Rachel A.J., Alikhan, Nabil-Fareed, Casey, Anna, Liggett, Steven, Caller, Laura G., Panchbhaya, Yasmin N., Forrest, Leysa M., Findlay, Jacqueline, Beggs, Andrew, Hesketh, Andrew R., Higginson, Ellen E., Aggarwal, Dinesh, Colquhoun, Rachel, Ashworth, Jordan, McCrone, J.T., Michell, Stephen L., Hughes, Margaret, Rainbow, Lucille, Haldenby, Sam T., Green, Luke R., Parker, Matthew D., Bridgewater, Hannah E., Alam, Mohammad T., Quail, Mike, Thurston, Scott, Beaver, Charlotte, McMinn, Liz, Puethe, Christoph, Tonkin-Hill, Gerry, Smith, Christen, Jamrozy, Dorota, Patel, Minal, Drury, Eleanor, Loman, Nicholas J.
Published in Cell

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

by Do, Ron, Stitziel, Nathan O, Won, Hong-Hee, Jørgensen, Anders Berg, Duga, Stefano, Angelica Merlini, Pier, Kiezun, Adam, Farrall, Martin, Goel, Anuj, Zuk, Or, Guella, Illaria, Asselta, Rosanna, Lange, Leslie A, Peloso, Gina M, Auer, Paul L, Girelli, Domenico, Martinelli, Nicola, Farlow, Deborah N, DePristo, Mark A, Roberts, Robert, Stewart, Alexander F R, Saleheen, Danish, Danesh, John, Epstein, Stephen E, Sivapalaratnam, Suthesh, Hovingh, G Kees, Kastelein, John J, Samani, Nilesh J, Schunkert, Heribert, Erdmann, Jeanette, Shah, Svati H, Kraus, William E, Davies, Robert, Nikpay, Majid, Johansen, Christopher T, Wang, Jian, Hegele, Robert A, Hechter, Eliana, Marz, Winfried, Kleber, Marcus E, Huang, Jie, Johnson, Andrew D, Li, Mingyao, Burke, Greg L, Gross, Myron, Liu, Yongmei, Assimes, Themistocles L, Heiss, Gerardo, Lange, Ethan M, Folsom, Aaron R, Taylor, Herman A, Olivieri, Oliviero, Hamsten, Anders, Clarke, Robert, Reilly, Dermot F, Yin, Wu, Rivas, Manuel A, Donnelly, Peter, Rossouw, Jacques E, Psaty, Bruce M, Herrington, David M, Wilson, James G, Rich, Stephen S, Bamshad, Michael J, Tracy, Russell P, Cupples, L Adrienne, Rader, Daniel J, Reilly, Muredach P, Spertus, John A, Cresci, Sharon, Hartiala, Jaana, Tang, W H Wilson, Hazen, Stanley L, Allayee, Hooman, Reiner, Alex P, Carlson, Christopher S, Kooperberg, Charles, Jackson, Rebecca D, Boerwinkle, Eric, Lander, Eric S, Schwartz, Stephen M, Siscovick, David S, McPherson, Ruth, Tybjaerg-Hansen, Anne, Abecasis, Goncalo R, Watkins, Hugh, Nickerson, Deborah A, Ardissino, Diego, Sunyaev, Shamil R, O'Donnell, Christopher J, Altshuler, David, Gabriel, Stacey, Kathiresan, Sekar
Published in Nature (London)

Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk

by Mavaddat, Nasim, Steyerberg, Ewout W., Pharoah, Paul D.P., Abu-Ful, Zumuruda, Anton-Culver, Hoda, Benitez, Javier, Bonanni, Bernardo, Brucker, Sara Y., Burwinkel, Barbara, Chenevix-Trench, Georgia, Choi, Ji-Yeob, Clarke, Christine L., Børresen-Dale, Anne-Lise, Sahlberg, Kristine, Ottestad, Lars, Schlichting, Ellen, Sauer, Toril, Engebråten, Olav, Naume, Bjørn, Kiserud, Cecile, Reinertsen, Kristin, Geisler, Jürgen, Alnæs, Grethe Grenaker, Collée, J. Margriet, Czene, Kamila, Daly, Mary B., Dwek, Miriam, Eccles, Diana M., Fasching, Peter A., Flyger, Henrik, Gago-Dominguez, Manuela, García-Sáenz, José A., González-Neira, Anna, Haiman, Christopher A., Hamann, Ute, Heemskerk-Gerritsen, Bernadette A.M., Pathmanathan, Nirmala, Simpson, Peter, Graham, J. Dinny, Sachchithananthan, Mythily, Balleine, Rosemary, Bennett, Ian, Brennan, Meagan, Brown, Melissa, Burke, Jo, Chauhan, Deepa, Dickson, Rebecca, Edkins, Ted, Edwards, Stacey, Field, Michael, Flanagan, James, Friedlander, Michael, George, Peter, Harris, Marion, Hayward, Nick, Hopper, John, Hunt, Clare, Kidd, Alexa, Kirk, Judy, Koehler, Jessica, Lawrence, Mitchell, McLachlan, Sue Anne, Patterson, Briony, Rickard, Edwina, Robinson, Bridget, Saleh, Mona, Salisbury, Elizabeth, Saunders, Christobel, Sexton, Adrienne, Southey, Melissa, Spurdle, Amanda, Visvader, Jane, Williams, Rachael, Ito, Hidemi, Jakimovska, Milena, Janni, Wolfgang, Kang, Daehee, Kristensen, Vessela N., Lubiński, Jan, Mannermaa, Arto, Margolin, Sara, Milne, Roger L., Muranen, Taru A., Neuhausen, Susan L., Peto, Julian, Petridis, Christos, Rennert, Gad, Romero, Atocha, Saloustros, Emmanouil, Sawyer, Elinor J., Schwentner, Lukas, Scott, Christopher, See, Mee-Hoong, Shen, Chen-Yang, Shu, Xiao-Ou, Spinelli, John J., Teo, Soo Hwang, van Ongeval, Chantal, van Veen, Elke M., Wolk, Alicja
Published in American journal of human genetics

The impact of coding germline variants on contralateral breast cancer risk and survival

by Morra, Anna, Mavaddat, Nasim, Muranen, Taru A., Allen, Jamie, Andrulis, Irene L., Auvinen, Päivi, Behrens, Sabine, Bolla, Manjeet K., Brauch, Hiltrud, Camp, Nicola J., Geisler, Jürgen, Grenaker Alnæs, Grethe I., Czene, Kamila, Decker, Brennan, Dorling, Leila, Ekici, Arif B., Fasching, Peter A., Gago-Dominguez, Manuela, García-Closas, Montserrat, Giles, Graham G., Guénel, Pascal, Gündert, Melanie, Hamann, Ute, Harrington, Patricia A., He, Wei, Hooning, Maartje J., Hoppe, Reiner, Howell, Anthony, Amor, David, Andrews, Lesley, Balleine, Rosemary, Bennett, Ian, Bogwitz, Michael, Botes, Leon, Caldon, Liz, Cao, Michelle, Chakrabarti, Anannya, Chauhan, Deepa, Cohen, Paul, Cui, James, DeFazio, Anna, Delatycki, Martin, Dixon, Joanne, Edkins, Ted, Farshid, Gelareh, Fellows, Andrew, Flanagan, James, Fox, Stephen, French, Juliet, Gaff, Clara, George, Peter, Hunt, Clare, Kidd, Alexa, Koehler, Jessica, Kollias, James, Li, Shuai, Lipton, Lara, Loi, Sherene, Mann, Graham, Marsh, Deborah, McLachlan, Sue Anne, Milne, Roger, Nightingale, Sophie, O'Sullivan, Sarah, Ortega, David Gallego, Pachter, Nick, Patterson, Briony, Phillips, Kelly, Ramus, Susan, Rickard, Edwina, Robinson, Bridget, Saleh, Mona, Skandarajah, Anita, Saunders, Christobel, Scott, Rodney, Sexton, Adrienne, Shelling, Andrew, Taylor, Jessica, Thorne, Heather, Visvader, Jane, Young, Mary Ann, Zaheed, Milita, Jakubowska, Anna, Keeman, Renske, Kristensen, Vessela N., Milne, Roger L., Mulligan, Anna Marie, Park-Simon, Tjoung-Won, Peterlongo, Paolo, Pharoah, Paul D.P., Rhenius, Valerie, Sawyer, Elinor J., Schmutzler, Rita K., Shah, Mitul, Tomlinson, Ian, Vreeswijk, Maaike P.G., Wendt, Camilla, Yang, Xiaohong R., Devilee, Peter, Easton, Douglas F.
Published in American journal of human genetics

Mendelian randomisation study of smoking exposure in relation to breast cancer risk

by Park, Hanla A, Neumeyer, Sonja, Michailidou, Kyriaki, Bolla, Manjeet K, Ahearn, Thomas U, Anton-Culver, Hoda, Antonenkova, Natalia N, Arndt, Volker, Aronson, Kristan J, Baten, Adinda, Beane Freeman, Laura E, Becher, Heiko, Beckmann, Matthias W, Benitez, Javier, Bermisheva, Marina, Bojesen, Stig E, Brauch, Hiltrud, Burwinkel, Barbara, Campa, Daniele, Castelao, Jose E, Chanock, Stephen J, Chenevix-Trench, Georgia, Clarke, Christine L, Conroy, Don M, Cox, Angela, Daly, Mary B, Devilee, Peter, Dörk, Thilo, Dos-Santos-Silva, Isabel, Eccles, Diana M, Eliassen, A Heather, Engel, Christoph, Evans, D Gareth, Fasching, Peter A, Fritschi, Lin, García-Closas, Montserrat, Goldberg, Mark S, Goldgar, David E, Guénel, Pascal, Hahnen, Eric, Haiman, Christopher A, Håkansson, Niclas, Hall, Per, Hamann, Ute, Han, Sileny, Harkness, Elaine F, Hart, Steven N, He, Wei, Heemskerk-Gerritsen, Bernadette A M, Jakubowska, Anna, Kaaks, Rudolf, Kapoor, Pooja Middha, Khusnutdinova, Elza, Koppert, Linetta B, Lacey, James, Le Marchand, Loic, Lubiński, Jan, Mannermaa, Arto, Manoochehri, Mehdi, Margolin, Sara, Martinez, Maria Elena, Mavroudis, Dimitrios, Meindl, Alfons, Menon, Usha, Muranen, Taru A, Nevanlinna, Heli, Newman, William G, Nordestgaard, Børge G, Olshan, Andrew F, Olsson, Håkan, Park-Simon, Tjoung-Won, Peterlongo, Paolo, Peto, Julian, Plaseska-Karanfilska, Dijana, Presneau, Nadege, Rennert, Hedy S, Romero, Atocha, Sawyer, Elinor J, Schmidt, Marjanka K, Scott, Christopher, Shu, Xiao-Ou, Simard, Jacques, Smeets, Ann, Southey, Melissa C, Spinelli, John J, Swerdlow, Anthony J, Tamimi, Rulla M, Tapper, William J, Taylor, Jack A, Terry, Mary Beth, Troester, Melissa A, Truong, Thérèse, Vachon, Celine M, van Veen, Elke M, Vijai, Joseph, Wendt, Camilla, Dunning, Alison M, Pharoah, Paul D P, Easton, Douglas F, Chang-Claude, Jenny
Published in British journal of cancer

CYP3A71C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers

by Johnson, Nichola, Maguire, Sarah, Jones, Michael E, Schoemaker, Minouk J, Gilham, Clare, Wang, Qin, Dennis, Joe, Ahearn, Thomas U, Andrulis, Irene L, Anton-Culver, Hoda, Arndt, Volker, Augustinsson, Annelie, Baynes, Caroline, Freeman, Laura E Beane, Benitez, Javier, Bermisheva, Marina, Blomqvist, Carl, Bogdanova, Natalia V, Bojesen, Stig E, Brauch, Hiltrud, Brenner, Hermann, Burwinkel, Barbara, Campa, Daniele, Canzian, Federico, Castelao, Jose E, Chenevix-Trench, Georgia, Conroy, Don M, Cox, Angela, Czene, Kamila, Eliassen, A Heather, Engel, Christoph, Fasching, Peter A, Figueroa, Jonine, Floris, Giuseppe, Gago-Dominguez, Manuela, Gapstur, Susan M, García-Closas, Montserrat, Goldberg, Mark S, González-Neira, Anna, Guénel, Pascal, Hahnen, Eric, Haiman, Christopher A, Håkansson, Niclas, Hall, Per, Hamann, Ute, Harrington, Patricia A, Howell, Anthony, Jager, Agnes, Keeman, Renske, Kitahara, Cari M, Kosma, Veli-Matti, Kraft, Peter, Kristensen, Vessela N, Kurian, Allison W, Lambrechts, Diether, Le Marchand, Loic, Lubiński, Jan, Mannermaa, Arto, Manoukian, Siranoush, Margolin, Sara, Martens, John W M, Mayes, Rebecca, Nevanlinna, Heli, Newman, William G, Nielsen, Sune F, Nordestgaard, Børge G, Obi, Nadia, Olshan, Andrew F, Olsson, Håkan, Orban, Ester, Park-Simon, Tjoung-Won, Peterlongo, Paolo, Plaseska-Karanfilska, Dijana, Pylkäs, Katri, Rennert, Gad, Rennert, Hedy S, Ruddy, Kathryn J, Sandler, Dale P, Sawyer, Elinor J, Scott, Christopher, Shu, Xiao-Ou, Spinelli, John J, Stone, Jennifer, Tamimi, Rulla M, Taylor, Jack A, Tomlinson, Ian, Truong, Thérèse, Vachon, Celine M, van Veen, Elke M, Wang, Sophia S, Wendt, Camilla, Wolk, Alicja, Pharoah, Paul D P, Howie, A Forbes, Dos-Santos-Silva, Isabel, Swerdlow, Anthony J, Chang-Claude, Jenny, Schmidt, Marjanka K, Orr, Nick, Fletcher, Olivia
Published in British journal of cancer

FANCM missense variants and breast cancer risk: a case-control association study of 75,156 European women

by Figlioli, Gisella, Billaud, Amandine, Ahearn, Thomas U, Antonenkova, Natalia N, Becher, Heiko, Beckmann, Matthias W, Behrens, Sabine, Benitez, Javier, Bermisheva, Marina, Blok, Marinus J, Bogdanova, Natalia V, Bonanni, Bernardo, Burwinkel, Barbara, Camp, Nicola J, Campbell, Archie, Castelao, Jose E, Cessna, Melissa H, Chanock, Stephen J, Czene, Kamila, Devilee, Peter, Dörk, Thilo, Engel, Christoph, Eriksson, Mikael, Fasching, Peter A, Figueroa, Jonine D, Gabrielson, Marike, Gago-Dominguez, Manuela, García-Closas, Montserrat, González-Neira, Anna, Grassmann, Felix, Guénel, Pascal, Gündert, Melanie, Hadjisavvas, Andreas, Hahnen, Eric, Hall, Per, Hamann, Ute, Harrington, Patricia A, He, Wei, Hillemanns, Peter, Hollestelle, Antoinette, Hooning, Maartje J, Hoppe, Reiner, Howell, Anthony, Humphreys, Keith, Jager, Agnes, Jakubowska, Anna, Khusnutdinova, Elza K, Ko, Yon-Dschun, Kristensen, Vessela N, Lindblom, Annika, Lissowska, Jolanta, Lubiński, Jan, Mannermaa, Arto, Manoukian, Siranoush, Margolin, Sara, Mavroudis, Dimitrios, Newman, William G, Obi, Nadia, Panayiotidis, Mihalis I, Rashid, Muhammad U, Rhenius, Valerie, Rookus, Matti A, Saloustros, Emmanouil, Sawyer, Elinor J, Schmutzler, Rita K, Shah, Mitul, Sironen, Reijo, Southey, Melissa C, Suvanto, Maija, Tollenaar, Rob A E M, Tomlinson, Ian, Truong, Thérèse, van der Kolk, Lizet E, van Veen, Elke M, Wappenschmidt, Barbara, Yang, Xiaohong R, Bolla, Manjeet K, Dennis, Joe, Dunning, Alison M, Easton, Douglas F, Lush, Michael, Michailidou, Kyriaki, Pharoah, Paul D P, Wang, Qin, Adank, Muriel A, Schmidt, Marjanka K, Andrulis, Irene L, Chang-Claude, Jenny, Nevanlinna, Heli, Chenevix-Trench, Georgia, Evans, D Gareth, Milne, Roger L, Radice, Paolo, Peterlongo, Paolo
Published in European journal of human genetics : EJHG

Association of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer‐specific survival

by Morra, Anna, Schreurs, Maartje A. C., Anton‐Culver, Hoda, Augustinsson, Annelie, Bojesen, Stig E., Brauch, Hiltrud, Buys, Saundra S., Castelao, Jose E., Cessna, Melissa H., Chung, Wendy K., Gram, Inger Torhild, Naume, Bjørn, Geisler, Jürgen, Cross, Simon S., Easton, Douglas F., Eccles, Diana M., Eriksson, Mikael, Evans, D. Gareth, Fehm, Tanja N., Flyger, Henrik, Gabrielson, Marike, García‐Sáenz, José A., Gündert, Melanie, Hahnen, Eric, Hartikainen, Jaana M., Hoppe, Reiner, Clarke, Christine, Marsh, Deborah, Carpenter, Jane, Pathmanathan, Nirmala, Graham, J. Dinny, Sachchithananthan, Mythily, Amor, David, Balleine, Rosemary, Beesley, Jonathan, Bennett, Ian, Burke, Jo, Butow, Phyllis, Campbell, Ian, Chenevix‐Trench, Georgia, Cohen, Paul, Crook, Ashley, Cui, James, Dawson, Sarah‐Jane, Dixon, Joanne, Edwards, Stacey, Fong, Peter, Gattas, Mike, George, Peter, Kollias, James, Lakhani, Sunil, Lee, Jason, Lindeman, Geoff, Lipton, Lara, Lobb, Liz, Marsh, Deborah, O’Connell, Shona, Pachter, Nick, Phillips, Kelly, Pieper, Ellen, Ramus, Susan, Rickard, Edwina, Saunus, Jodi, Scott, Rodney, Scott, Clare, Shelling, Andrew, Taylor, Jessica, Taylor, Renea, Thorne, Heather, Trainer, Alison, Tucker, Kathy, Walker, Logan, Winship, Ingrid, Zaheed, Milita, Jakubowska, Anna, Jernström, Helena, John, Esther M., Kristensen, Vessela N., Lambrechts, Diether, Lindblom, Annika, Lubiński, Jan, Lux, Michael P., Mulligan, Anna Marie, Muranen, Taru A., Newman, William G., Obi, Nadia, Patel, Alpa V., Phillips, Kelly‐Anne, Plaseska‐Karanfilska, Dijana, Presneau, Nadege, Pylkäs, Katri, Rashid, Muhammad U., Sawyer, Elinor J., Schuetze, Sabine, Tapper, William J., Troester, Melissa A., Veen, Elke M., Wang, Qin, Winqvist, Robert, Ziogas, Argyrios
Published in Cancer medicine (Malden, MA)

Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study

by Gibson, Lorna, Jones, Michael E, Schoemaker, Minouk J, Haynes, Ben P, Hopper, John L, Southey, Melissa C, Dite, Gillian S, Schmidt, Marjanka K, Van't Veer, Laura J, Fasching, Peter A, Ekici, Arif B, Renner, Stefan P, Kerin, Michael, Miller, Nicola, Schneeweiss, Andreas, Sohn, Christof, Guénel, Pascal, Cordina, Emilie, Menegaux, Florence, Flyger, Henrik, Milne, Roger, Benitez, Javier, Bernstein, Leslie, Anton-Culver, Hoda, Arndt, Volker, Dieffenbach, Aida Karina, Schmutzler, Rita K, Brauch, Hiltrud, Justenhoven, Christina, Ko, Yon-Dschun, Nevanlinna, Heli, Muranen, Taru A, Aittomäki, Kristiina, Blomqvist, Carl, Bogdanova, Natalia V, Lindblom, Annika, Mannermaa, Arto, Kataja, Vesa, Kosma, Veli-Matti, Hartikainen, Jaana M, Chenevix-Trench, Georgia, Wu, Anna H, Lambrechts, Diether, Chang-Claude, Jenny, Flesch-Janys, Dieter, Radice, Paolo, Peterlongo, Paolo, Fredericksen, Zachary, Pankratz, Vernon S, Haiman, Chris, Simard, Jacques, Labrèche, France, Soucy, Penny, Teo, Soo, Yip, Cheng Har, Phuah, Sze Yee, Cornes, Belinda K, Børresen-Dale, Anne-Lise, Zheng, Wei, Winqvist, Robert, Pylkäs, Katri, Grip, Mervi, Andrulis, Irene L, Glendon, Gord, Figueroa, Jonine, Chanock, Stephen J, Schoof, Nils, Hooning, Maartje, Hollestelle, Antoinette, Oldenburg, Rogier A, Tilanus-Linthorst, Madeleine, Liu, Jianjun, Brock, Ian W, Cross, Simon S, Signorello, Lisa B, Kang, Daehee, Noh, Dong-Young, Park, Sue K, Choi, Ji-Yeob, Lim, Wei Yen, Tang, Anthony, Hamann, Ute, Ulmer, Hans Ulrich, Jakubowska, Anna, Jaworska-Bieniek, Katarzyna, Slager, Susan, Toland, Amanda E, Vachon, Celine, Yannoukakos, Drakoulis, Shen, Chen-Yang, Huang, Chiun-Sheng, González-Neira, Anna, Tessier, Daniel C, Luccarini, Craig, Dennis, Joe, Michailidou, Kyriaki, Bolla, Manjeet K, Wang, Jean, Swerdlow, Anthony J, Peto, Julian
Published in Breast cancer research : BCR