Genetic analysis of ALS cases in the isolated island population of Malta by Borg, Rebecca, Farrugia Wismayer, Maia, Bonavia, Karl, Farrugia Wismayer, Andrew, Vella, Malcolm, van Vugt, Joke J F A, Kenna, Brendan J, Kenna, Kevin P, Vassallo, Neville, Veldink, Jan H, Cauchi, Ruben J

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Transcription factor Pebbled/RREB1 regulates injury-induced axon degeneration by Farley, Jonathan E., Burdett, Thomas C., Barria, Romina, Neukomm, Lukas J., Kenna, Kevin P., Landers, John E., Freeman, Marc R.

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Exome-wide Rare Variant Analysis Identifies TUBA4A Mutations Associated with Familial ALS by Smith, Bradley N., Ticozzi, Nicola, Fallini, Claudia, Gkazi, Athina Soragia, Topp, Simon, Kenna, Kevin P., Scotter, Emma L., Kost, Jason, Keagle, Pamela, Miller, Jack W., Calini, Daniela, Vance, Caroline, Danielson, Eric W., Troakes, Claire, Tiloca, Cinzia, Al-Sarraj, Safa, Lewis, Elizabeth A., King, Andrew, Colombrita, Claudia, Pensato, Viviana, Castellotti, Barbara, de Belleroche, Jacqueline, Baas, Frank, ten Asbroek, Anneloor LMA, Sapp, Peter C., McKenna-Yasek, Diane, McLaughlin, Russell L., Polak, Meraida, Asress, Seneshaw, Esteban-Pérez, Jesús, Muñoz-Blanco, José Luis, Simpson, Michael, D’Alfonso, Sandra, Mazzini, Letizia, Comi, Giacomo P., Del Bo, Roberto, Ceroni, Mauro, Gagliardi, Stella, Querin, Giorgia, Bertolin, Cinzia, van Rheenen, Wouter, Diekstra, Frank P., Lauria, Giuseppe, Duga, Stefano, Corti, Stefania, Cereda, Cristina, Corrado, Lucia, Sorarù, Gianni, Morrison, Karen E., Williams, Kelly L., Nicholson, Garth A., Blair, Ian P., Dion, Patrick A., Leblond, Claire S., Rouleau, Guy A., Hardiman, Orla, Veldink, Jan H., van den Berg, Leonard H., Al-Chalabi, Ammar, Pall, Hardev, Shaw, Pamela J., Turner, Martin R., Talbot, Kevin, Taroni, Franco, García-Redondo, Alberto, Wu, Zheyang, Glass, Jonathan D., Gellera, Cinzia, Ratti, Antonia, Brown, Robert H., Silani, Vincenzo, Shaw, Christopher E., Landers, John E.

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Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study by Byrne, Susan, Dr, Elamin, Marwa, MD, Bede, Peter, MD, Shatunov, Aleksey, PhD, Walsh, Cathal, PhD, Corr, Bernie, MSc, Heverin, Mark, MSc, Jordan, Norah, MSc, Kenna, Kevin, BSc, Lynch, Catherine, MSc, McLaughlin, Russell L, BSc, Iyer, Parameswaran Mahadeva, MD, O'Brien, Caoimhe, MSc, Phukan, Julie, PhD, Wynne, Brona, BSc, Bokde, Arun L, PhD, Bradley, Daniel G, Prof, Pender, Niall, PhD, Al-Chalabi, Ammar, Prof, Hardiman, Orla, Prof

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ALS-associated missense and nonsense TBK1 mutations can both cause loss of kinase function by de Majo, Martina, Topp, Simon D., Smith, Bradley N., Nishimura, Agnes L., Chen, Han-Jou, Gkazi, Athina Soragia, Miller, Jack, Wong, Chun Hao, Vance, Caroline, Baas, Frank, ten Asbroek, Anneloor L.M.A., Kenna, Kevin P., Ticozzi, Nicola, Redondo, Alberto Garcia, Esteban-Pérez, Jesús, Tiloca, Cinzia, Verde, Federico, Duga, Stefano, Morrison, Karen E., Shaw, Pamela J., Kirby, Janine, Turner, Martin R., Talbot, Kevin, Hardiman, Orla, Glass, Jonathan D., de Belleroche, Jacqueline, Gellera, Cinzia, Ratti, Antonia, Al-Chalabi, Ammar, Brown, Robert H., Silani, Vincenzo, Landers, John E., Shaw, Christopher E.

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The project MinE databrowser: bringing large-scale whole-genome sequencing in ALS to researchers and the public by van der Spek, Rick A.A., van Rheenen, Wouter, Pulit, Sara L., Kenna, Kevin P., van den Berg, Leonard H., Veldink, Jan H.

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Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis by Zhang, Sai, Cooper-Knock, Johnathan, Weimer, Annika K., Shi, Minyi, Moll, Tobias, Marshall, Jack N.G., Harvey, Calum, Nezhad, Helia Ghahremani, Franklin, John, Souza, Cleide dos Santos, Ning, Ke, Wang, Cheng, Li, Jingjing, Dilliott, Allison A., Farhan, Sali, Elhaik, Eran, Pasniceanu, Iris, Livesey, Matthew R., Eitan, Chen, Hornstein, Eran, Kenna, Kevin P., Blair, Ian, Wray, Naomi R., Kiernan, Matthew, Mitne Neto, Miguel, Chio, Adriano, Cauchi, Ruben, Robberecht, Wim, van Damme, Philip, Corcia, Philippe, Couratier, Philippe, Hardiman, Orla, McLaughin, Russell, Gotkine, Marc, Drory, Vivian, Ticozzi, Nicola, Silani, Vincenzo, Veldink, Jan H., van den Berg, Leonard H., de Carvalho, Mamede, Mora Pardina, Jesus S., Povedano, Monica, Andersen, Peter, Weber, Markus, Başak, Nazli A., Al-Chalabi, Ammar, Shaw, Chris, Shaw, Pamela J., Morrison, Karen E., Landers, John E., Glass, Jonathan D., Veldink, Jan H., Ferraiuolo, Laura, Shaw, Pamela J., Snyder, Michael P.

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Rare variant burden analysis within enhancers identifies CAV1 as an ALS risk gene by Cooper-Knock, Johnathan, Zhang, Sai, Kenna, Kevin P., Moll, Tobias, Franklin, John P., Allen, Samantha, Nezhad, Helia Ghahremani, Iacoangeli, Alfredo, Yacovzada, Nancy Y., Eitan, Chen, Hornstein, Eran, Elhaik, Eran, Celadova, Petra, Bose, Daniel, Farhan, Sali, Fishilevich, Simon, Lancet, Doron, Morrison, Karen E., Shaw, Christopher E., Al-Chalabi, Ammar, Veldink, Jan H., Kirby, Janine, Snyder, Michael P., Shaw, Pamela J.

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Using Reference Databases of Genetic Variation to Evaluate the Potential Pathogenicity of Candidate Disease Variants by Kenna, Kevin P., McLaughlin, Russell L., Hardiman, Orla, Bradley, Daniel G.

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Rare and common genetic determinants of mitochondrial function determine severity but not risk of amyotrophic lateral sclerosis by Harvey, Calum, Weinreich, Marcel, Lee, James A.K., Shaw, Allan C., Ferraiuolo, Laura, Mortiboys, Heather, Zhang, Sai, Hop, Paul J., Zwamborn, Ramona A.J., van Eijk, Kristel, Julian, Thomas H., Moll, Tobias, Iacoangeli, Alfredo, Al Khleifat, Ahmad, Quinn, John P., Pfaff, Abigail L., Kõks, Sulev, Poulton, Joanna, Battle, Stephanie L., Arking, Dan E., Snyder, Michael P., Veldink, Jan H., Kenna, Kevin P., Shaw, Pamela J., Cooper-Knock, Johnathan

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Multiomic analysis reveals cell-type-specific molecular determinants of COVID-19 severity by Zhang, Sai, Cooper-Knock, Johnathan, Weimer, Annika K., Shi, Minyi, Kozhaya, Lina, Unutmaz, Derya, Harvey, Calum, Julian, Thomas H., Furini, Simone, Frullanti, Elisa, Fava, Francesca, Renieri, Alessandra, Gao, Peng, Shen, Xiaotao, Timpanaro, Ilia Sarah, Kenna, Kevin P., Baillie, J. Kenneth, Davis, Mark M., Tsao, Philip S., Snyder, Michael P.

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Homozygosity mapping in an Irish ALS case–control cohort describes local demographic phenomena and points towards potential recessive risk loci by McLaughlin, Russell L., Kenna, Kevin P., Vajda, Alice, Heverin, Mark, Byrne, Susan, Donaghy, Colette G., Cronin, Simon, Bradley, Daniel G., Hardiman, Orla

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Analysis of the hexanucleotide repeat expansion and founder haplotype at C9ORF72 in an Irish psychosis case-control sample by Fahey, Ciara, Byrne, Susan, McLaughlin, Russell, Kenna, Kevin, Shatunov, Aleksey, Donohoe, Gary, Gill, Michael, Al-Chalabi, Ammar, Bradley, Daniel G, Hardiman, Orla, Corvin, Aiden P, Morris, Derek W

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A second-generation Irish genome-wide association study for amyotrophic lateral sclerosis by McLaughlin, Russell L, Kenna, Kevin P, Vajda, Alice, Bede, Peter, Elamin, Marwa, Cronin, Simon, Donaghy, Colette G, Bradley, Daniel G, Hardiman, Orla

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Unbiased metabolome screen leads to personalized medicine strategy for amyotrophic lateral sclerosis by Boddy, Sarah, Islam, Mahjabin, Moll, Tobias, Kurz, Julian, Burrows, David, McGown, Alexander, Bhargava, Anushka, Julian, Thomas H, Harvey, Calum, Marshall, Jack NG, Hall, Benjamin PC, Allen, Scott P, Kenna, Kevin P, Sanderson, Eleanor, Zhang, Sai, Ramesh, Tennore, Snyder, Michael P, Shaw, Pamela J, McDermott, Christopher, Cooper-Knock, Johnathan

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Rare Variant Burden Analysis within Enhancers Identifies CAV1 as an ALS Risk Gene by Cooper-Knock, Johnathan, Zhang, Sai, Kenna, Kevin P., Moll, Tobias, Franklin, John P., Allen, Samantha, Nezhad, Helia Ghahremani, Iacoangeli, Alfredo, Yacovzada, Nancy Y., Eitan, Chen, Hornstein, Eran, Elhaik, Eran, Celadova, Petra, Bose, Daniel, Farhan, Sali, Fishilevich, Simon, Lancet, Doron, Morrison, Karen E., Shaw, Christopher E., Al-Chalabi, Ammar, Blair, Ian, Wray, Naomi, Kiernan, Matthew, Neto, Miguel Mitne, Chio, Adriano, Cauchi, Ruben, Robberecht, Wim, van Damme, Philip, Corcia, Phillippe, Couratier, Phillipe, Hardiman, Orla, McLaughlin, Russel, Gotkine, Marc, Drory, Vivan, Ticozzi, Nicola, Silani, Vincenzo, Veldink, Jan, van den Berg, Leonard, de Carvalho, Mamede, Pardina, Jesus Mora, Povedano, Monica, Andersen, Peter, Wber, Markus, Başak, Nazli, Al-Chalabi, Ammar, Shaw, Christopher, Shaw, Pamela, Morrison, Karen, Landers, John, Glass, Jonathan, Veldink, Jan H., Kirby, Janine, Snyder, Michael P., Shaw, Pamela J.

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Reconsidering the causality of TIA1 mutations in ALS by van der Spek, Rick A., van Rheenen, Wouter, Pulit, Sara L., Kenna, Kevin P., Ticozzi, Nicola, Kooyman, Maarten, Mclaughlin, Russell L., Moisse, Matthieu, van Eijk, Kristel R., van Vugt, Joke J. F. A., Iacoangeli, Alfredo, Andersen, Peter, Nazli Basak, A., Blair, Ian, de Carvalho, Mamede, Chio, Adriano, Corcia, Philippe, Couratier, Phillipe, Drory, Vivian E., Glass, Jonathan D., Hardiman, Orla, Mora, Jesús S., Morrison, Karen E., Mitne-Neto, Miguel, Robberecht, Wim, Shaw, Pamela J., Panadés, Monica P., van Damme, Philip, Silani, Vincenzo, Gotkine, Marc, Weber, Markus, van Es, Michael A., Landers, John E., Al-Chalabi, Ammar, van den Berg, Leonard H., Veldink, Jan H.

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Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways by Cirulli, Elizabeth T., Lasseigne, Brittany N., Petrovski, Slavé, Sapp, Peter C., Dion, Patrick A., Leblond, Claire S., Couthouis, Julien, Lu, Yi-Fan, Wang, Quanli, Krueger, Brian J., Ren, Zhong, Keebler, Jonathan, Han, Yujun, Levy, Shawn E., Boone, Braden E., Wimbish, Jack R., Waite, Lindsay L., Jones, Angela L., Carulli, John P., Day-Williams, Aaron G., Staropoli, John F., Xin, Winnie W., Chesi, Alessandra, Raphael, Alya R., McKenna-Yasek, Diane, Cady, Janet, de Jong, J. M. B. Vianney, Kenna, Kevin P., Smith, Bradley N., Topp, Simon, Miller, Jack, Gkazi, Athina, Al-Chalabi, Ammar, van den Berg, Leonard H., Veldink, Jan, Silani, Vincenzo, Ticozzi, Nicola, Shaw, Christopher E., Baloh, Robert H., Appel, Stanley, Simpson, Ericka, Lagier-Tourenne, Clotilde, Pulst, Stefan M., Gibson, Summer, Trojanowski, John Q., Elman, Lauren, McCluskey, Leo, Grossman, Murray, Shneider, Neil A., Chung, Wendy K., Ravits, John M., Glass, Jonathan D., Sims, Katherine B., Van Deerlin, Vivianna M., Maniatis, Tom, Hayes, Sebastian D., Ordureau, Alban, Swarup, Sharan, Landers, John, Baas, Frank, Allen, Andrew S., Bedlack, Richard S., Harper, J. Wade, Gitler, Aaron D., Rouleau, Guy A., Brown, Robert, Harms, Matthew B., Cooper, Gregory M., Harris, Tim, Myers, Richard M., Goldstein, David B.

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Aggregation of neurologic and neuropsychiatric disease in amyotrophic lateral sclerosis kindreds: A population-based case-control cohort study of familial and sporadic amyotrophic... by Byrne, Susan, Heverin, Mark, Elamin, Marwa, Bede, Peter, Lynch, Catherine, Kenna, Kevin, MacLaughlin, Russell, Walsh, Cathal, Al Chalabi, Ammar, Hardiman, Orla

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Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis by Wouter Van Rheenen, Pulit, Sara L, Dekker, Annelot M, Ahmad Al Khleifat, Brands, William J, Iacoangeli, Alfredo, Kenna, Kevin P, Kavak, Ersen, Kooyman, Maarten, McLaughlin, Russell L, Middelkoop, Bas, Moisse, Matthieu, Schellevis, Raymond D, Shatunov, Aleksey, Sproviero, William, Tazelaar, Gijs H P, Rick A A Van der Spek, Perry T C Van Doormaal, Van Eijk, Kristel R, Joke Van Vugt, Basak, A Nazli, Blair, Ian P, Glass, Jonathan D, Hardiman, Orla, Hide, Winston, Landers, John E, Mora, Jesus S, Morrison, Karen E, Newhouse, Stephen, Robberecht, Wim, Shaw, Christopher E, Shaw, Pamela J, Philip Van Damme, Van Es, Michael A, Wray, Naomi R, Al-Chalabi, Ammar, Leonard H Van den Berg, Veldink, Jan H

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