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Search Results - Kelleher, Eugene W
Search Results - Kelleher, Eugene W
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Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates
by
Duvall, Jeremy R.
,
Thomas, Joshua D.
,
Bukhalid, Raghida A.
,
Catcott, Kalli C.
,
Bentley, Keith W.
,
Collins, Scott D.
,
Eitas, Timothy
,
Jones, Brian D.
,
Kelleher, Eugene W.
,
Lancaster, Kelly
,
Protopopova, Marina
,
Ray, Soumya S.
,
Ter-Ovanesyan, Elena
,
Xu, Ling
,
Yang, Liping
,
Zurita, Jeffrey
,
Damelin, Marc
,
Toader, Dorin
,
Lowinger, Timothy B.
Published in
Journal of medicinal chemistry
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Discovery of 3‑(3-(4-(1-Aminocyclobutyl)phenyl)-5-phenyl‑3H‑imidazo[4,5‑b]pyridin-2-yl)pyridin-2-amine (ARQ 092): An Orally Bioavailable, Selective, and Potent Allosteric AKT Inhib...
by
Lapierre, Jean-Marc
,
Eathiraj, Sudharshan
,
Vensel, David
,
Liu, Yanbin
,
Bull, Cathy O
,
Cornell-Kennon, Susan
,
Iimura, Shin
,
Kelleher, Eugene W
,
Kizer, Darin E
,
Koerner, Steffi
,
Makhija, Sapna
,
Matsuda, Akihisa
,
Moussa, Magdi
,
Namdev, Nivedita
,
Savage, Ronald E
,
Szwaya, Jeff
,
Volckova, Erika
,
Westlund, Neil
,
Wu, Hui
,
Schwartz, Brian
Published in
Journal of medicinal chemistry
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Abstract 1738: XMT-2056, a well-tolerated, Immunosynthen-based STING-agonist antibody-drug conjugate which induces anti-tumor immune activity
by
Duvall, Jeremy R.
,
Bukhalid, Raghida A.
,
Cetinbas, Naniye M.
,
Catcott, Kalli C.
,
Slocum, Kelly
,
Avocetien, Kenneth
,
Bentley, Keith W.
,
Bradley, Stephen
,
Clardy, Susan
,
Collins, Scott D.
,
Ditty, Elizabeth
,
Eitas, Timothy
,
Jones, Brian D.
,
Kelleher, Eugene W.
,
Lee, Winnie
,
Monnell, Travis
,
Mosher, Rebecca
,
Protopopova, Marina
,
Qin, LiuLiang
,
Shaw, Pamela
,
Ter-Ovanesyan, Elena
,
Thomas, Joshua D.
,
Wongthida, Phonphimon
,
Xu, Ling
,
Yang, Liping
,
Zurita, Jeffrey
,
Toader, Dorin
,
Damelin, Marc
,
Lowinger, Timothy B.
Published in
Cancer research (Chicago, Ill.)
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Abstract 6706: Systemic administration of STING agonist antibody-drug conjugates elicit potent anti-tumor immune responses with minimal induction of circulating cytokines
by
Bukhalid, Raghida A.
,
Duvall, Jeremy R.
,
Cetinbas, Naniye Malli
,
Catcott, Kalli C.
,
Avocetien, Kenneth
,
Bentley, Keith W.
,
Bradley, Stephen
,
Carter, Tyler
,
Chin, Chen-Ni
,
Clardy, Susan
,
Collins, Scott D.
,
Eitas, Timothy
,
Jones, Brian D.
,
Kelleher, Eugene W.
,
Mosher, Rebecca
,
Nazzaro, Mark
,
Protopopova, Marina
,
Shaw, Pamela
,
Slocum, Kelly
,
Ter-Ovanesyan, Elena
,
Qin, LiuLiang
,
Thomas, Joshua D.
,
Xu, Ling
,
Yang, Liping
,
Zurita, Jeffrey
,
Toader, Dorin
,
Damelin, Marc
,
Lowinger, Timothy B.
Published in
Cancer research (Chicago, Ill.)
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Abstract 3503: XMT-2056, a HER2-targeted Immunosynthen STING-agonist antibody-drug conjugate, binds a novel epitope of HER2 and shows increased anti-tumor activity in combination w...
by
Duvall, Jeremy R.
,
Bukhalid, Raghida A.
,
Cetinbas, Naniye M.
,
Catcott, Kalli C.
,
Lancaster, Kelly
,
Bentley, Keith W.
,
Clark, Suzanna
,
Clardy, Susan
,
Collins, Scott D.
,
Dirksen, Anouk
,
Ditty, Elizabeth
,
Du, Bingfan
,
Kelleher, Eugene W.
,
Monnell, Travis
,
Protopopova, Marina
,
Routhier, Caitlin
,
Stevenson, Cheri
,
Ter-Ovanesyan, Elena
,
Thomas, Joshua D.
,
Uttard, Alex
,
Wang, Jason
,
Wongthida, Phonphimon
,
Xu, Ling
,
Yau, Annika
,
Zurita, Jeffrey
,
Toader, Dorin
,
Damelin, Marc
,
Lowinger, Timothy B.
Published in
Cancer research (Chicago, Ill.)
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Discovery of 3-(3-(4-(1-Aminocyclobutyl)phenyl)-5-phenyl-3 H -imidazo[4,5- b ]pyridin-2-yl)pyridin-2-amine (ARQ 092): An Orally Bioavailable, Selective, and Potent Allosteric AKT I...
by
Lapierre, Jean-Marc
,
Eathiraj, Sudharshan
,
Vensel, David
,
Liu, Yanbin
,
Bull, Cathy O.
,
Cornell-Kennon, Susan
,
Iimura, Shin
,
Kelleher, Eugene W.
,
Kizer, Darin E.
,
Koerner, Steffi
,
Makhija, Sapna
,
Matsuda, Akihisa
,
Moussa, Magdi
,
Namdev, Nivedita
,
Savage, Ronald E.
,
Szwaya, Jeff
,
Volckova, Erika
,
Westlund, Neil
,
Wu, Hui
,
Schwartz, Brian
Published in
Journal of medicinal chemistry
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Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen
by
Drake, Charles G.
,
Doody, Amy D.H.
,
Mihalyo, Marianne A.
,
Huang, Ching-Tai
,
Kelleher, Erin
,
Ravi, Sowmya
,
Hipkiss, Edward L.
,
Flies, Dallas B.
,
Kennedy, Eugene P.
,
Long, Meixiao
,
McGary, Patrick W.
,
Coryell, Lee
,
Nelson, William G.
,
Pardoll, Drew M.
,
Adler, Adam J.
Published in
Cancer cell
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Timing of Vaccine Therapy May be Important in Prostate Cancer
Published in
Cancer biology & therapy
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