Discovery of Futibatinib: The First Covalent FGFR Kinase Inhibitor in Clinical Use by Ito, Satoru, Otsuki, Sachie, Ohsawa, Hirokazu, Hirano, Atsushi, Kazuno, Hideki, Yamashita, Satoshi, Egami, Kosuke, Shibata, Yoshihiro, Yamamiya, Ikuo, Yamashita, Fumiaki, Kodama, Yasuo, Funabashi, Kaoru, Kazuno, Hiromi, Komori, Toshiharu, Suzuki, Satoshi, Sootome, Hiroshi, Hirai, Hiroshi, Sagara, Takeshi

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Structure and activity of specific inhibitors of thymidine phosphorylase to potentiate the function of antitumor 2′-deoxyribonucleosides by Fukushima, Masakazu, Suzuki, Norihiko, Emura, Tomohiro, Yano, Shingo, Kazuno, Hideki, Tada, Yukio, Yamada, Yuji, Asao, Tetsuji

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Abstract 3600: The prominent safety profile of TAS-115, a novel c-Met + VEGFR dual kinase inhibitor can lead to potentiate the efficacy via durable inhibition of angiogenesis by Ochiiwa, Hiroaki, Fujita, Hidenori, Ito, Kimihiro, Takenaka, Toru, Huang, Jinhong, Ito, Satoko, Suzuki, Takamasa, Egami, Kousuke, Suefuji, Takashi, Sato, Ayako, Sato, Tsudoi, Fujioka, Yayoi, Kato, Masanori, Aoyagi, Yoshimi, Hashimoto, Akihiro, Kazuno, Hideki, Miyadera, Kazutaka, Suda, Yoshimitsu, Yonekura, Kazuhiko

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Synthesis and evaluation of 6-methylene-bridged uracil derivatives. Part 1: Discovery of novel orally active inhibitors of human thymidine phosphorylase by Yano, Shingo, Kazuno, Hideki, Suzuki, Norihiko, Emura, Tomohiro, Wierzba, Konstanty, Yamashita, Jun-ichi, Tada, Yukio, Yamada, Yuji, Fukushima, Masakazu, Asao, Tetsuji

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The novel VEGF receptor/MET-targeted kinase inhibitor TAS-115 has marked in vivo antitumor properties and a favorable tolerability profile by Fujita, Hidenori, Miyadera, Kazutaka, Kato, Masanori, Fujioka, Yayoi, Ochiiwa, Hiroaki, Huang, Jinhong, Ito, Kimihiro, Aoyagi, Yoshimi, Takenaka, Toru, Suzuki, Takamasa, Ito, Satoko, Hashimoto, Akihiro, Suefuji, Takashi, Egami, Kosuke, Kazuno, Hideki, Suda, Yoshimitsu, Nishio, Kazuto, Yonekura, Kazuhiko

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Molecular modeling study of the thymidine phosphorylase inhibitor by SBDD and classical QSAR analysis by Tada, Yukio, Kazuno, Hideki, Sato, Tsutomu, Suzuki, Norihiko, Emura, Tomohiro, Yano, Shingo

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The first total synthesis of tetronasin (M139603) by Hori, Kozo, Kazuno, Hideki, Nomura, Keiichi, Yoshii, Eiichi

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Abstract A245: TAS-115, a novel potent dual MET/VEGFRs inhibitor, has highly safer profile leading to more potent efficacy in vivo by Kato, Masanori, Fujita, Hidenori, Miyadera, Kazutaka, Fujioka, Yayoi, Ochiiwa, Hiroaki, Huang, Jinhong, Ito, Kimihiro, Aoyagi, Yoshimi, Takenaka, Toru, Suzuki, Takamasa, Ito, Satoko, Hashimoto, Akihiro, Suefuji, Takashi, Sato, Ayako, Egami, Kosuke, Kazuno, Hideki, Suda, Yoshimitsu, Yonekura, Kazuhiko

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Synthesis and evaluation of 6-methylene-bridged uracil derivatives. Part 2: Optimization of inhibitors of human thymidine phosphorylase and their selectivity with uridine phosphory... by Yano, Shingo, Kazuno, Hideki, Sato, Tsutomu, Suzuki, Norihiko, Emura, Tomohiro, Wierzba, Konstanty, Yamashita, Jun-ichi, Tada, Yukio, Yamada, Yuji, Fukushima, Masakazu, Asao, Tetsuji

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Abstract 3577: TAS-115: a highly potent c-Met + VEGFRs dual inhibitor with prominently safer profile by Fujita, Hidenori, Miyadera, Kazutaka, Ito, Kimihiro, Takenaka, Toru, Huang, Jinhong, Ito, Satoko, Suzuki, Takamasa, Ochiiwa, Hiroaki, Egami, Kousuke, Suefuji, Takashi, Sato, Ayako, Sato, Tsudoi, Fujioka, Yayoi, Kato, Masanori, Aoyagi, Yoshimi, Hashimoto, Akihiro, Kazuno, Hideki, Suda, Yoshimitsu, Yonekura, Kazuhiko

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SBDDとclassical QSAR 解析によるチミジンホスホリラーゼ阻害薬の分子設計 by 多田, 幸雄, 数野, 秀樹, 佐藤, 勉, 鈴木, 則彦, 江村, 智弘, 矢野, 伸吾

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Highly sensitive visual restoration and protection via ectopic expression of chimeric rhodopsin in mice by Katada, Yusaku, Yoshida, Kazuho, Serizawa, Naho, Lee, Deokho, Kobayashi, Kenta, Negishi, Kazuno, Okano, Hideyuki, Kandori, Hideki, Tsubota, Kazuo, Kurihara, Toshihide

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Preventive procedure for stenosis after esophagojejunostomy using a circular stapler and transorally inserted anvil (OrVil™) following laparoscopic proximal gastrectomy and total g... by Nomura, Eiji, Kayano, Hajime, Seki, Takatoshi, Abe, Rin, Yoshii, Hisamichi, Uda, Shuji, Kazuno, Akihito, Izumi, Hideki, Yamamoto, Soichiro, Mukai, Masaya, Makuuchi, Hiroyasu

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Non-Perfusion Area Index for Prognostic Prediction in Diabetic Retinopathy by Ofuji, Yoshiko, Katada, Yusaku, Tomita, Yohei, Nagai, Norihiro, Sonobe, Hideki, Watanabe, Kazuhiro, Shinoda, Hajime, Ozawa, Yoko, Negishi, Kazuno, Tsubota, Kazuo, Kurihara, Toshihide

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Risk factor profiles, drug usage, and prevalence of aspirin-associated gastroduodenal injuries among high-risk cardiovascular Japanese patients: the results from the MAGIC study by Uemura, Naomi, Sugano, Kentaro, Hiraishi, Hideyuki, Shimada, Kazuyuki, Goto, Shinya, Uchiyama, Shinichiro, Okada, Yasushi, Origasa, Hideki, Ikeda, Yasuo

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Comprehensive and long-term surveys of COVID-19 sequelae in Japan, an ambidirectional multicentre cohort study: study protocol by Nakagawara, Kensuke, Namkoong, Ho, Terai, Hideki, Masaki, Katsunori, Tanosaki, Takae, Shimamoto, Kyoko, Lee, Ho, Tanaka, Hiromu, Okamori, Satoshi, Kabata, Hiroki, Chubachi, Shotaro, Ikemura, Shinnosuke, Kamata, Hirofumi, Yasuda, Hiroyuki, Kawada, Ichiro, Ishii, Makoto, Ishibashi, Yoshiki, Harada, Sei, Fujita, Takanori, Ito, Daisuke, Bun, Shogyoku, Tabuchi, Hajime, Kanzaki, Sho, Shimizu, Eisuke, Fukuda, Keitaro, Yamagami, Jun, Kobayashi, Keigo, Hirano, Toshiyuki, Inoue, Takashi, Kagyo, Junko, Shiomi, Tetsuya, Ohgino, Keiko, Sayama, Koichi, Otsuka, Kengo, Miyao, Naoki, Odani, Toshio, Oyamada, Yoshitaka, Masuzawa, Keita, Nakayama, Sohei, Suzuki, Yusuke, Baba, Rie, Nakachi, Ichiro, Kuwahara, Naota, Ishiguro, Takashi, Mashimo, Shuko, Minematsu, Naoto, Ueda, Soichiro, Manabe, Tadashi, Funatsu, Yohei, Koh, Hidefumi, Yoshiyama, Takashi, Saito, Fumitake, Ishioka, Kota, Takahashi, Saeko, Nakamura, Morio, Goto, Ai, Harada, Norihiro, Kusaka, Yu, Nakano, Yasushi, Nishio, Kazumi, Tateno, Hiroki, Edahiro, Ryuya, Takeda, Yoshito, Kumanogoh, Atsushi, Kodama, Nobuhiro, Okamoto, Masaki, Umeda, Akira, Hagimura, Kazuto, Sato, Toshiro, Miyazaki, Naoki, Takemura, Ryo, Sato, Yasunori, Takebayashi, Toru, Nakahara, Jin, Mimura, Masaru, Ogawa, Kaoru, Shimmura, Shigeto, Negishi, Kazuno, Tsubota, Kazuo, Amagai, Masayuki, Goto, Rei, Ibuka, Yoko, Hasegawa, Naoki, Kitagawa, Yuko, Kanai, Takanori, Fukunaga, Koichi

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Prospective Cohort Study of Gastrointestinal Complications and Vascular Diseases in Patients Taking Aspirin: Rationale and Design of the MAGIC Study by Origasa, Hideki, Goto, Shinya, Shimada, Kazuyuki, Uchiyama, Shinichiro, Okada, Yasushi, Sugano, Kentaro, Hiraishi, Hideyuki, Uemura, Naomi, Ikeda, Yasuo

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