Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells

by Durai, Sundar, Mani, Mala, Kandavelou, Karthikeyan, Wu, Joy, Porteus, Matthew H., Chandrasegaran, Srinivasan
Published in Nucleic acids research

Binding of two zinc finger nuclease monomers to two specific sites is required for effective double-strand DNA cleavage

by Mani, Mala, Smith, Jeff, Kandavelou, Karthikeyan, Berg, Jeremy M., Chandrasegaran, Srinivasan
Published in Biochemical and biophysical research communications

'Magic' scissors for genome surgery

by Kandavelou, Karthikeyan, Mani, Mala, Durai, Sundar, Chandrasegaran, Srinivasan
Published in Nature biotechnology

Creating Designed Zinc-Finger Nucleases with Minimal Cytotoxicity

by Ramalingam, Sivaprakash, Kandavelou, Karthikeyan, Rajenderan, Raja, Chandrasegaran, Srinivasan
Published in Journal of molecular biology

Total Synthesis of a Functional Designer Eukaryotic Chromosome

by Annaluru, Narayana, Muller, Héloïse, Mitchell, Leslie A., Ramalingam, Sivaprakash, Stracquadanio, Giovanni, Richardson, Sarah M., Dymond, Jessica S., Kuang, Zheng, Scheifele, Lisa Z., Cooper, Eric M., Cai, Yizhi, Zeller, Karen, Agmon, Neta, Han, Jeffrey S., Hadjithomas, Michalis, Tullman, Jennifer, Caravelli, Katrina, Cirelli, Kimberly, Guo, Zheyuan, London, Viktoriya, Yeluru, Apurva, Murugan, Sindurathy, Kandavelou, Karthikeyan, Agier, Nicolas, Fischer, Gilles, Yang, Kun, Martin, Andrew, Bilgel, Murat, Bohutski, Pavlo, Boulier, Kristin M., Capaldo, Brian J., Chang, Joy, Charoen, Kristie, Choi, Woo Jin, Deng, Peter, DiCarlo, James E., Doong, Judy, Dunn, Jessilyn, Feinberg, Jason I., Fernandez, Christopher, Floria, Charlotte E., Gladowski, David, Hadidi, Pasha, Ishizuka, Isabel, Jabbari, Javaneh, Lau, Calvin Y. L., Lee, Pablo A., Li, Sean, Lin, Denise, Linder, Matthias E., Ling, Jonathan, Liu, Jaime, Liu, Jonathan, London, Mariya, Ma, Henry, Mao, Jessica, McDade, Jessica E., McMillan, Alexandra, Moore, Aaron M., Oh, Won Chan, Ouyang, Yu, Patel, Ruchi, Paul, Marina, Paulsen, Laura C., Qiu, Judy, Rhee, Alex, Rubashkin, Matthew G., Soh, Ina Y., Sotuyo, Nathaniel E., Srinivas, Venkatesh, Suarez, Allison, Wong, Andy, Wong, Remus, Xie, Wei Rose, Xu, Yijie, Yu, Allen T., Koszul, Romain, Bader, Joel S., Boeke, Jef D., Chandrasegaran, Srinivasan
Published in Science (American Association for the Advancement of Science)

Design, engineering, and characterization of zinc finger nucleases

by Mani, Mala, Kandavelou, Karthikeyan, Dy, Fei Jamie, Durai, Sundar, Chandrasegaran, Srinivasan
Published in Biochemical and biophysical research communications

Targeted manipulation of mammalian genomes using designed zinc finger nucleases

by Kandavelou, Karthikeyan, Ramalingam, Sivaprakash, London, Viktoriya, Mani, Mala, Wu, Joy, Alexeev, Vitali, Civin, Curt I., Chandrasegaran, Srinivasan
Published in Biochemical and biophysical research communications

Deletion of a Mycobacterium tuberculosis Proteasomal ATPase Homologue Gene Produces a Slow-Growing Strain That Persists in Host Tissues

by Lamichhane, Gyanu, Raghunand, Tirumalai R., Morrison, Norman E., Woolwine, Samuel C., Tyagi, Sandeep, Kandavelou, Karthikeyan, Bishai, William R.
Published in The Journal of infectious diseases