Exome sequencing identifies frequent mutation of the SWI / SNF complex gene PBRM1 in renal carcinoma

by VARELA, Ignacio, TARPEY, Patrick, BIGNELL, Graham, BUTLER, Adam, CHO, Juok, DALGLIESH, Gillian L, GALAPPATHTHIGE, Danushka, GREENMAN, Chris, HARDY, Claire, MINGMING JIA, LATIMER, Calli, KING WAI LAU, RAINE, Keiran, MARSHALL, John, MCLAREN, Stuart, MENZIES, Andrew, MUDIE, Laura, STEBBINGS, Lucy, LARGAESPADA, David A, WESSELS, L. F. A, RICHARD, Stephane, KAHNOSKI, Richard J, ANEMA, John, DACHUAN HUANG, TUVESON, David A, PEREZ-MANCERA, Pedro A, MUSTONEN, Ville, FISCHER, Andrej, ADAMS, David J, RUST, Alistair, CHAN-ON, Waraporn, SUBIMERB, Chutima, DYKEMA, Karl, FURGE, Kyle, CHOON KIAT ONG, CAMPBELL, Peter J, BIN TEAN TEH, STRATTON, Michael R, FUTREAL, P. Andrew, STEPHENS, Philip, DAVIES, Helen, JONES, David, LIN, Meng-Lay, TEAGUE, Jon
Published in Nature (London)

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

by Teh, Bin Tean, Stratton, Michael R, Futreal, P. Andrew, Dalgliesh, Gillian L, Furge, Kyle, Greenman, Chris, Chen, Lina, Bignell, Graham, Butler, Adam, Davies, Helen, Edkins, Sarah, Hardy, Claire, Latimer, Calli, Teague, Jon, Andrews, Jenny, Barthorpe, Syd, Beare, Dave, Buck, Gemma, Campbell, Peter J, Forbes, Simon, Jia, Mingming, Jones, David, Knott, Henry, Kok, Chai Yin, Lau, King Wai, Leroy, Catherine, Lin, Meng-Lay, McBride, David J, Maddison, Mark, Maguire, Simon, McLay, Kirsten, Menzies, Andrew, Mironenko, Tatiana, Mulderrig, Lee, Mudie, Laura, O'Meara, Sarah, Pleasance, Erin, Rajasingham, Arjunan, Shepherd, Rebecca, Smith, Raffaella, Stebbings, Lucy, Stephens, Philip, Tang, Gurpreet, Tarpey, Patrick S, Turrell, Kelly, Dykema, Karl J, Khoo, Sok Kean, Petillo, David, Wondergem, Bill, Anema, John, Kahnoski, Richard J
Published in Nature (London)

Exome-wide Sequencing Shows Low Mutation Rates and Identifies Novel Mutated Genes in Seminomas

by Cutcutache, Ioana, Suzuki, Yuka, Tan, Iain Beehuat, Ramgopal, Subhashini, Zhang, Shenli, Ramnarayanan, Kalpana, Gan, Anna, Lee, Heng Hong, Tay, Su Ting, Ooi, Aikseng, Ong, Choon Kiat, Bolthouse, Jonathan T, Lane, Brian R, Anema, John G, Kahnoski, Richard J, Tan, Patrick, Teh, Bin Tean, Rozen, Steven G
Published in European urology

Recognizing the Continuous Nature of Expression Heterogeneity and Clinical Outcomes in Clear Cell Renal Cell Carcinoma

by Wei, Xiaona, Choudhury, Yukti, Lim, Weng Khong, Anema, John, Kahnoski, Richard J, Lane, Brian, Ludlow, John, Takahashi, Masayuki, Kanayama, Hiro-Omi, Belldegrun, Arie, Kim, Hyung L, Rogers, Craig, Nicol, David, Teh, Bin Tean, Tan, Min-Han
Published in Scientific reports

Critical appraisal of first-generation renal tumor complexity scoring systems: Creation of a second-generation model of tumor complexity

by Tobert, Conrad M., M.D, Shoemaker, Allen, Ph.D, Kahnoski, Richard J., M.D, Lane, Brian R., M.D., Ph.D
Published in Urologic oncology

Prevalence of Proteinuria and Other Abnormalities in Urinalysis Performed in the Urology Clinic

by Bezinque, Adam, Noyes, Sabrina L, Kirmiz, Samer, Parker, Jessica, Dey, Sumi, Kahnoski, Richard J, Lane, Brian R
Published in Urology (Ridgewood, N.J.)

Expression of the PTTG1 Oncogene Is Associated with Aggressive Clear Cell Renal Cell Carcinoma

by WONDERGEM, Bill, ZHONGFA ZHANG, KAHNOSKI, Richard J, FURGE, Kyle A, BIN TEAN TEH, DACHUAN HUANG, CHOON KIAT ONG, KOEMAN, Julie, VAN'T HOF, David, PETILLO, David, OOI, Aikseng, ANEMA, John, LANE, Brian
Published in Cancer research (Chicago, Ill.)

RENAL Nephrometry Score Predicts Surgery Type Independent of Individual Surgeon's Use of Nephron-sparing Surgery

by Tobert, Conrad M, Kahnoski, Richard J, Thompson, David E, Anema, John G, Kuntzman, Randall S, Lane, Brian R
Published in Urology (Ridgewood, N.J.)

Activation of the PI3K/AKT pathway induces urothelial carcinoma of the renal pelvis: identification in human tumors and confirmation in animal models

by Qian, Chao-Nan, Furge, Kyle A, Knol, Jared, Huang, Dan, Chen, Jindong, Dykema, Karl J, Kort, Eric J, Massie, Aaron, Khoo, Sok Kean, Vanden Beldt, Kristin, Resau, James H, Anema, John, Kahnoski, Richard J, Morreau, Hans, Camparo, Philippe, Comperat, Eva, Sibony, Mathilde, Denoux, Yves, Molinie, Vincent, Vieillefond, Annick, Eng, Charis, Williams, Bart O, Teh, Bin Tean
Published in Cancer research (Chicago, Ill.)

Somatic Pairing of Chromosome 19 in Renal Oncocytoma Is Associated with Deregulated ELGN2-Mediated Oxygen-Sensing Response

by Koeman, Julie M, Russell, Ryan C, Tan, Min-Han, Petillo, David, Westphal, Michael, Koelzer, Katherine, Metcalf, Julie L, Zhang, Zhongfa, Matsuda, Daisuke, Dykema, Karl J, Houseman, Heather L, Kort, Eric J, Furge, Laura L, Kahnoski, Richard J, Richard, Stephane, Vieillefond, Annick, Swiatek, Pamela J, Teh, Bin Tean, Ohh, Michael, Furge, Kyle A
Published in PLoS genetics

Identification of copy number alterations and its association with pathological features in clear cell and papillary RCC

by Matsuda, Daisuke, Khoo, Sok Kean, Massie, Aaron, Iwamura, Masatsugu, Chen, Jindong, Petillo, David, Wondergem, Bill, Avallone, Michael, Kloostra, Stephanie J, Tan, Min-Han, Koeman, Julie, Zhang, Zhongfa, Kahnoski, Richard J, Baba, Shiro, Teh, Bin Tean
Published in Cancer letters

The influence of obesity-related factors in the etiology of renal cell carcinoma-A mendelian randomization study

by Johansson, Mattias, Carreras-Torres, Robert, Scelo, Ghislaine, Purdue, Mark P, Mariosa, Daniela, Muller, David C, Timpson, Nicolas J, Haycock, Philip C, Brown, Kevin M, Ye, Yuanqing, Hofmann, Jonathan N, Foll, Matthieu, Gaborieau, Valerie, Machiela, Mitchell J, Colli, Leandro M, Garnier, Jean-Guillaume, Blanche, Helene, Burdette, Laurie, Skryabin, Konstantin G, Yeager, Meredith, Radojevic-Skodric, Sanja, Ognjanovic, Simona, Foretova, Lenka, Holcatova, Ivana, Janout, Vladimir, Mates, Dana, Mukeriya, Anush, Rascu, Stefan, Zaridze, David, Bencko, Vladimir, Cybulski, Cezary, Fabianova, Eleonora, Jinga, Viorel, Lissowska, Jolanta, Lubinski, Jan, Navratilova, Marie, Rudnai, Peter, Cancel-Tassin, Geraldine, Cussenot, Olivier, Weiderpass, Elisabete, Ljungberg, Börje, Tumkur Sitaram, Raviprakash, Häggström, Christel, Bruinsma, Fiona, Jordan, Susan J, Severi, Gianluca, Winship, Ingrid, Hveem, Kristian, Vatten, Lars J, Fletcher, Tony, Larsson, Susanna C, Wolk, Alicja, Banks, Rosamonde E, Selby, Peter J, Easton, Douglas F, Andreotti, Gabriella, Beane Freeman, Laura E, Koutros, Stella, Männistö, Satu, Weinstein, Stephanie, Edwards, Todd L, Lipworth, Loren, Gapstur, Susan M, Stevens, Victoria L, Carol, Hallie, Freedman, Matthew L, Pomerantz, Mark M, Cho, Eunyoung, Gaziano, J Michael, Sesso, Howard D, Parker, Alexander S, Eckel-Passow, Jeanette E, Huang, Wen-Yi, Kahnoski, Richard J, Lane, Brian R, Noyes, Sabrina L, Petillo, David, Teh, Bin Tean, Peters, Ulrike, White, Emily, Johnson, Lisa, Luo, Juhua, Buring, Julie, Lee, I-Min, Moore, Lee E, Eisen, Timothy, Henrion, Marc, Larkin, James, Barman, Poulami, Leibovich, Bradley C, Choueiri, Toni K, Lathrop, G Mark, McKay, James D, Wu, Xifeng, Houlston, Richard S, Chanock, Stephen J, Relton, Caroline, Richards, J Brent, Davey Smith, George, Brennan, Paul
Published in Nature methods

Genome-wide association study identifies multiple risk loci for renal cell carcinoma

by Scelo, Ghislaine, Wang, Zhaoming, Ye, Yuanqing, Hofmann, Jonathan N, Choi, Jiyeon, Machiela, Mitchell J, Li, Peng, Sampson, Joshua N, Abedi-Ardekani, Behnoush, Besse, Celine, Blanche, Helene, Burdette, Laurie, Chabrier, Amelie, Durand, Geoffroy, Le Calvez-Kelm, Florence, Robinot, Nivonirina, Wozniak, Magdalena B, Yeager, Meredith, Basta-Jovanovic, Gordana, Dzamic, Zoran, Foretova, Lenka, Holcatova, Ivana, Mates, Dana, Mukeriya, Anush, Rascu, Stefan, Zaridze, David, Bencko, Vladimir, Cybulski, Cezary, Fabianova, Eleonora, Lissowska, Jolanta, Lubinski, Jan, Navratilova, Marie, Rudnai, Peter, Szeszenia-Dabrowska, Neonila, Benhamou, Simone, Cancel-Tassin, Geraldine, Cussenot, Olivier, Baglietto, Laura, Khaw, Kay-Tee, Weiderpass, Elisabete, Ljungberg, Borje, Sitaram, Raviprakash T, Jordan, Susan J, Severi, Gianluca, Winship, Ingrid, Hveem, Kristian, Vatten, Lars J, Fletcher, Tony, Koppova, Kvetoslava, Larsson, Susanna C, Wolk, Alicja, Banks, Rosamonde E, Selby, Peter J, Easton, Douglas F, Pharoah, Paul, Andreotti, Gabriella, Albanes, Demetrius, Männistö, Satu, Weinstein, Stephanie, Clark, Peter E, Edwards, Todd L, Lipworth, Loren, Gapstur, Susan M, Stevens, Victoria L, Carol, Hallie, Freedman, Matthew L, Pomerantz, Mark M, Kraft, Peter, Preston, Mark A, Wilson, Kathryn M, Michael Gaziano, J, Sesso, Howard D, Freedman, Neal D, Huang, Wen-Yi, Anema, John G, Kahnoski, Richard J, Lane, Brian R, Noyes, Sabrina L, Petillo, David, Teh, Bin Tean, Peters, Ulrike, White, Emily, Anderson, Garnet L, Johnson, Lisa, Buring, Julie, Chow, Wong-Ho, Moore, Lee E, Wood, Christopher, Eisen, Timothy, Henrion, Marc, Larkin, James, Leibovich, Bradley C, Choueiri, Toni K, Mark Lathrop, G, Rothman, Nathaniel, Deleuze, Jean-Francois, Parker, Alexander S, Wu, Xifeng, Brennan, Paul, Chanock, Stephen J
Published in Nature communications

Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma

by Machiela, Mitchell J., Hofmann, Jonathan N., Carreras-Torres, Robert, Brown, Kevin M., Johansson, Mattias, Wang, Zhaoming, Foll, Matthieu, Li, Peng, Rothman, Nathaniel, McKay, James D., Ye, Yuanqing, Henrion, Marc, Bruinsma, Fiona, Jordan, Susan, Severi, Gianluca, Hveem, Kristian, Vatten, Lars J., Larsson, Susanna C., Wolk, Alicja, Banks, Rosamonde E., Selby, Peter J., Easton, Douglas F., Pharoah, Paul, Andreotti, Gabriella, Freeman, Laura E. Beane, Albanes, Demetrius, Mannisto, Satu, Weinstein, Stephanie, Edwards, Todd E., Lipworth, Loren, Gapstur, Susan M., Stevens, Victoria L., Carol, Hallie, Freedman, Matthew L., Cho, Eunyoung, Kraft, Peter, Preston, Mark A., Wilson, Kathryn M., Gaziano, J. Michael, Sesso, Howard S., Freedman, Neal D., Huang, Wen-Yi, Anema, John G., Kahnoski, Richard J., Lane, Brian R., Noyes, Sabrina L., Petillo, David, Colli, Leandro M., Sampson, Joshua N., Besse, Celine, Blanche, Helene, Boland, Anne, Burdette, Laurie, Prokhortchouk, Egor, Skryabin, Konstantin G., Mijuskovic, Mirjana, Ognjanovic, Miodrag, Foretova, Lenka, Holcatova, Ivana, Janout, Vladimir, Mates, Dana, Mukeriya, Anush, Rascu, Stefan, Zaridze, David, Bencko, Vladimir, Cybulski, Cezary, Fabianova, Eleonora, Jinga, Viorel, Lissowska, Jolanta, Lubinski, Jan, Navratilova, Marie, Rudnai, Peter, Szeszenia-Dabrowska, Neonila, Benhamou, Simone, Cancel-Tassin, Geraldine, Cussenot, Olivier, Bueno-de-Mesquita, H. Bas, Canzian, Federico, Duell, Eric J., Sitaram, Raviprakash T., Peters, Ulrike, White, Emily, Anderson, Garnet L., Johnson, Lisa, Luo, Juhua, Buring, Julie, Lee, I-Min, Chow, Wong-Ho, Wood, Christopher, Eisen, Timothy, Larkin, James, Choueiri, Toni K., Lathrop, G. Mark, Teh, Bin Tean, Deleuze, Jean-Francois, Wu, Xifeng, Houlston, Richard S., Chanock, Stephen J., Scelo, Ghislaine, Purdue, Mark P.
Published in European urology

Somatic pairing of chromosome 19 in renal oncocytoma is associated with deregulated EGLN2-mediated [corrected] oxygen-sensing response

by Koeman, Julie M, Russell, Ryan C, Tan, Min-Han, Petillo, David, Westphal, Michael, Koelzer, Katherine, Metcalf, Julie L, Zhang, Zhongfa, Matsuda, Daisuke, Dykema, Karl J, Houseman, Heather L, Kort, Eric J, Furge, Laura L, Kahnoski, Richard J, Richard, Stéphane, Vieillefond, Annick, Swiatek, Pamela J, Teh, Bin Tean, Ohh, Michael, Furge, Kyle A
Published in PLoS genetics

Sex specific associations in genome wide association analysis of renal cell carcinoma

by Laskar, Ruhina S, Muller, David C, Li, Peng, Machiela, Mitchell J, Ye, Yuanqing, Gaborieau, Valerie, Foll, Matthieu, Hofmann, Jonathan N, Colli, Leandro, Sampson, Joshua N, Bacq-Daian, Delphine, Boland, Anne, Abedi-Ardekani, Behnoush, Durand, Geoffroy, Le Calvez-Kelm, Florence, Robinot, Nivonirina, Blanche, Helene, Skryabin, Konstantin G, Burdett, Laurie, Yeager, Meredith, Radojevic-Skodric, Sanja, Savic, Slavisa, Foretova, Lenka, Holcatova, Ivana, Janout, Vladimir, Mates, Dana, Rascu, Stefan, Mukeria, Anush, Zaridze, David, Bencko, Vladimir, Cybulski, Cezary, Fabianova, Eleonora, Jinga, Viorel, Lubinski, Jan, Navratilova, Marie, Rudnai, Peter, Świątkowska, Beata, Benhamou, Simone, Cancel-Tassin, Geraldine, Cussenot, Olivier, Trichopoulou, Antonia, Overvad, Kim, Panico, Salvatore, Ljungberg, Borje, Sitaram, Raviprakash T, Giles, Graham G, Milne, Roger L, Severi, Gianluca, Bruinsma, Fiona, Fletcher, Tony, Koppova, Kvetoslava, Larsson, Susanna C, Banks, Rosamonde E, Selby, Peter J, Easton, Douglas F, Pharoah, Paul, Andreotti, Gabriella, Beane Freeman, Laura E, Koutros, Stella, Albanes, Demetrius, Männistö, Satu, Weinstein, Stephanie, Clark, Peter E, Edwards, Todd L, Lipworth, Loren, Carol, Hallie, Freedman, Matthew L, Pomerantz, Mark M, Cho, Eunyoung, Kraft, Peter, Preston, Mark A, Wilson, Kathryn M, Michael Gaziano, J, Sesso, Howard D, Black, Amanda, Freedman, Neal D, Anema, John G, Kahnoski, Richard J, Lane, Brian R, Noyes, Sabrina L, Petillo, David, Peters, Ulrike, White, Emily, Anderson, Garnet L, Johnson, Lisa, Luo, Juhua, Chow, Wong-Ho, Moore, Lee E, Choueiri, Toni K, Wood, Christopher, Johansson, Mattias, McKay, James D, Brown, Kevin M, Lathrop, Mark G, Deleuze, Jean-Francois, Wu, Xifeng, Brennan, Paul, Chanock, Stephen J, Purdue, Mark P, Scelo, Ghislaine
Published in European journal of human genetics : EJHG

Microarray gene expression profiling using core biopsies of renal neoplasia

by Rogers, Craig G, Ditlev, Jonathon A, Tan, Min-Han, Sugimura, Jun, Qian, Chao-Nan, Cooper, Jeff, Lane, Brian, Jewett, Michael A, Kahnoski, Richard J, Kort, Eric J, Teh, Bin T
Published in American journal of translational research

Corrigendum re “Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma” [Eur Urol 2017;72:747–54]

by Machiela, Mitchell J., Hofmann, Jonathan N., Carreras-Torres, Robert, Brown, Kevin M., Johansson, Mattias, Wang, Zhaoming, Foll, Matthieu, Li, Peng, Rothman, Nathaniel, McKay, James D., Ye, Yuanqing, Henrion, Marc, Bruinsma, Fiona, Jordan, Susan, Severi, Gianluca, Hveem, Kristian, Vatten, Lars J., Larsson, Susanna C., Wolk, Alicja, Banks, Rosamonde E., Selby, Peter J., Easton, Douglas F., Pharoah, Paul, Andreotti, Gabriella, Freeman, Laura E. Beane, Albanes, Demetrius, Mannisto, Satu, Weinstein, Stephanie, Edwards, Todd E., Lipworth, Loren, Gapstur, Susan M., Stevens, Victoria L., Carol, Hallie, Freedman, Matthew L., Cho, Eunyoung, Kraft, Peter, Preston, Mark A., Wilson, Kathryn M., Gaziano, J. Michael, Sesso, Howard S., Freedman, Neal D., Huang, Wen-Yi, Anema, John G., Kahnoski, Richard J., Lane, Brian R., Noyes, Sabrina L., Petillo, David, Colli, Leandro M., Sampson, Joshua N., Besse, Celine, Blanche, Helene, Boland, Anne, Burdette, Laurie, Prokhortchouk, Egor, Skryabin, Konstantin G., Mijuskovic, Mirjana, Ognjanovic, Miodrag, Foretova, Lenka, Holcatova, Ivana, Janout, Vladimir, Mates, Dana, Mukeriya, Anush, Rascu, Stefan, Zaridze, David, Bencko, Vladimir, Cybulski, Cezary, Fabianova, Eleonora, Jinga, Viorel, Lissowska, Jolanta, Lubinski, Jan, Navratilova, Marie, Rudnai, Peter, Szeszenia-Dabrowska, Neonila, Benhamou, Simone, Cancel-Tassin, Geraldine, Cussenot, Olivier, Bueno-de-Mesquita, H.B(as)., Canzian, Federico, Duell, Eric J., Sitaram, Raviprakash T., Peters, Ulrike, White, Emily, Anderson, Garnet L., Johnson, Lisa, Luo, Juhua, Buring, Julie, Lee, I-Min, Chow, Wong-Ho, Wood, Christopher, Eisen, Timothy, Larkin, James, Choueiri, Toni K., Lathrop, G. Mark, Teh, Bin Tean, Deleuze, Jean-Francois, Wu, Xifeng, Houlston, Richard S., Chanock, Stephen J., Scelo, Ghislaine, Purdue, Mark P.
Published in European urology

Fear of recurrence, treatment satisfaction, and quality of life after radical prostatectomy for prostate cancer

by Hart, Stacey L., Latini, David M., Cowan, Janet E., Carroll, Peter R.
Published in Supportive care in cancer

Abstract 2805: Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

by Varela, Ignacio, Tarpey, Patrick, Raine, Keiran, Huang, Dachuan, Ong, Choon Kiat, Stephens, Philip, Davies, Helen, Jones, David, Lin, Meng-Lay, Teague, Jon, Bignell, Graham, Butler, Adam, Cho, Juok, Dalgliesh, Gillian L., Galappaththige, Danushka, Greenman, Chris, Hardy, Claire, Jia, Mingming, Latimer, Calli, Lau, King Wai, Marshall, John, McLaren, Stuart, Menzies, Andrew, Mudie, Laura, Stebbings, Lucy, Largaespada, David A., Wessels, L.F.A., Richard, Stéphane, Kahnoski, Richard J., Anema, John, Tuveson, David, Perez-Mancera, Pedro, Mustonen, Ville, Fischer, Andrej, Adams, David J., Rust, Alistair, Chan-on, Waraporn, Subimerb, Chutima, Dykema, Karl, Furge, Kyle A., Campbell, Peter J., Teh, Bin Tean, Stratton, Michael R., Futreal, P. Andrew
Published in Cancer research (Chicago, Ill.)