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Search Results - KANE-CARSON, Laurie
Search Results - KANE-CARSON, Laurie
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Dabrafenib; preclinical characterization, increased efficacy when combined with trametinib, while BRAF/MEK tool combination reduced skin lesions
by
King, Alastair J
,
Arnone, Marc R
,
Bleam, Maureen R
,
Moss, Katherine G
,
Yang, Jingsong
,
Fedorowicz, Kelly E
,
Smitheman, Kimberly N
,
Erhardt, Joseph A
,
Hughes-Earle, Angela
,
Kane-Carson, Laurie S
,
Sinnamon, Robert H
,
Qi, Hongwei
,
Rheault, Tara R
,
Uehling, David E
,
Laquerre, Sylvie G
Published in
PloS one
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Discovery of Dabrafenib: A Selective Inhibitor of Raf Kinases with Antitumor Activity against B‑Raf-Driven Tumors
by
Rheault, Tara R.
,
Stellwagen, John C.
,
Adjabeng, George M.
,
Hornberger, Keith R.
,
Petrov, Kimberly G.
,
Waterson, Alex G.
,
Dickerson, Scott H.
,
Mook, Robert A.
,
Laquerre, Sylvie G.
,
King, Alastair J.
,
Rossanese, Olivia W.
,
Arnone, Marc R.
,
Smitheman, Kimberly N.
,
Kane-Carson, Laurie S.
,
Han, Chao
,
Moorthy, Ganesh S.
,
Moss, Katherine G.
,
Uehling, David E.
Published in
ACS medicinal chemistry letters
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Synthesis and evaluation of pyrazolo[1,5-b]pyridazines as selective cyclin dependent kinase inhibitors
by
Stevens, Kirk L.
,
Reno, Michael J.
,
Alberti, Jennifer B.
,
Price, Daniel J.
,
Kane-Carson, Laurie S.
,
Knick, Victoria B.
,
Shewchuk, Lisa M.
,
Hassell, Anne M.
,
Veal, James M.
,
Davis, Stephen T.
,
Griffin, Robert J.
,
Peel, Michael R.
Published in
Bioorganic & medicinal chemistry
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Discovery and in vitro evaluation of potent kinase inhibitors: Pyrido[1′,2′:1,5]pyrazolo[3,4- d]pyrimidines
by
Alberti, Michael J.
,
Auten, Elizabeth P.
,
Lackey, Karen E.
,
McDonald, Octerloney B.
,
Wood, Edgar R.
,
Preugschat, Frank
,
Cutler, Geoffrey J.
,
Kane-Carson, Laurie
,
Liu, Wei
,
Jung, David K.
Published in
Bioorganic & medicinal chemistry letters
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Abstract B88: A selective Raf kinase inhibitor induces cell death and tumor regression of human cancer cell lines encoding B-RafV600E mutation
by
Laquerre, Sylvie
,
Arnone, Marc
,
Moss, Katherine
,
Yang, Jingsong
,
Fisher, Kelly
,
Kane-Carson, Laurie S.
,
Smitheman, Kimberly
,
Ward, Jessica
,
Heidrich, Bradley
,
Rheault, Tara
,
Adjabeng, George
,
Hornberger, Keith
,
Stellwagen, John
,
Waterson, Alex
,
Han, Chao
,
Mook, Robert A.
,
Uehling, David
,
King, Alastair J.
Published in
Molecular cancer therapeutics
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Design and effective synthesis of novel templates, 3,7-diphenyl-4-amino-thieno and furo-[3,2- c]pyridines as protein kinase inhibitors and in vitro evaluation targeting angiogeneti...
by
Miyazaki, Yasushi
,
Nakano, Masato
,
Sato, Hideyuki
,
Truesdale, Anne T.
,
Stuart, J. Darren
,
Nartey, Eldridge N.
,
Hightower, Kendra E.
,
Kane-Carson, Laurie
Published in
Bioorganic & medicinal chemistry letters
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Discovery and in vitro evaluation of potent kinase inhibitors : Pyrido[1',2':1,5]pyrazolo[3,4-d]pyrimidines: G-protein-coupled receptors in drug discovery
by
ALBERTI, Michael J
,
AUTEN, Elizabeth P
,
LACKEY, Karen E
,
MCDONALD, Octerloney B
,
WOOD, Edgar R
,
PREUGSCHAT, Frank
,
CUTLER, Geoffrey J
,
KANE-CARSON, Laurie
,
WEI LIU
,
JUNG, David K
Published in
Bioorganic & medicinal chemistry letters
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