Clonal hematopoiesis, with and without candidate driver mutations, is common in the elderly

by Zink, Florian, Stacey, Simon N., Norddahl, Gudmundur L., Frigge, Michael L., Magnusson, Olafur T., Jonsdottir, Ingileif, Thorgeirsson, Thorgeir E., Sigurdsson, Asgeir, Gudjonsson, Sigurjon A., Gudmundsson, Julius, Jonasson, Jon G., Tryggvadottir, Laufey, Jonsson, Thorvaldur, Helgason, Agnar, Gylfason, Arnaldur, Sulem, Patrick, Rafnar, Thorunn, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F., Masson, Gisli, Kong, Augustine, Stefansson, Kari
Published in Blood

Parental origin of sequence variants associated with complex diseases

by Gudjonsson, Sigurjon A, Sigurdsson, Helgi, Kristinsson, Kari Th, Sigurdsson, Asgeir, Hreidarsson, Astradur B, Masson, Gisli, Ferguson-Smith, Anne C, Frigge, Michael L, Jonsson, Thorvaldur, Stacey, Simon N, Olafsson, Jon H, Benediktsdottir, Kristrun R, Gudbjartsson, Daniel F, Besenbacher, Soren, Gylfason, Arnaldur, Sigurgeirsson, Bardur, Olason, Pall I, Sverrisson, Sverrir, Stefansson, Kari, Johannsson, Oskar Th, Thorsteinsdottir, Unnur, Benediktsson, Rafn, Thorleifsson, Gudmar, Kong, Augustine, Steinthorsdottir, Valgerdur, Sulem, Patrick, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Sigurdsson, Gunnar
Published in Nature (London)

A genome-wide association study yields five novel thyroid cancer risk loci

by Gudmundsson, Julius, Thorleifsson, Gudmar, Sigurdsson, Jon K, Stefansdottir, Lilja, Jonasson, Jon G, Gudjonsson, Sigurjon A, Gudbjartsson, Daniel F, Masson, Gisli, Johannsdottir, Hrefna, Halldorsson, Gisli H, Stacey, Simon N, Helgason, Hannes, Sulem, Patrick, Senter, Leigha, He, Huiling, Liyanarachchi, Sandya, Ringel, Matthew D, Aguillo, Esperanza, Panadero, Angeles, Prats, Enrique, Garcia-Castaño, Almudena, De Juan, Ana, Rivera, Fernando, Xu, Li, Kiemeney, Lambertus A, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Olafsson, Isleifur, Kristvinsson, Hoskuldur, Netea-Maier, Romana T, Jonsson, Thorvaldur, Mayordomo, Jose I, Plantinga, Theo S, Hjartarson, Hannes, Hrafnkelsson, Jon, Sturgis, Erich M, Thorsteinsdottir, Unnur, Rafnar, Thorunn, de la Chapelle, Albert, Stefansson, Kari
Published in Nature communications

Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA

by Gudmundsson, Julius, Sigurdsson, Jon K, Stefansdottir, Lilja, Agnarsson, Bjarni A, Isaksson, Helgi J, Stefansson, Olafur A, Gudjonsson, Sigurjon A, Gudbjartsson, Daniel F, Masson, Gisli, Frigge, Michael L, Stacey, Simon N, Sulem, Patrick, Halldorsson, Gisli H, Tragante, Vinicius, Holm, Hilma, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Olafsson, Isleifur, Jonsson, Thorvaldur, Jonsson, Eirikur, Barkardottir, Rosa B, Hilmarsson, Rafn, Asselbergs, Folkert W, Geirsson, Gudmundur, Thorsteinsdottir, Unnur, Rafnar, Thorunn, Thorleifsson, Gudmar, Stefansson, Kari
Published in Nature communications

In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden

by Agustsson, Arnar S, Birgisson, Helgi, Agnarsson, Bjarni A, Jonsson, Thorvaldur, Stefansdottir, Hrefna, Wärnberg, Fredrik, Lambe, Mats, Tryggvadottir, Laufey, Sverrisdottir, Asgerdur
Published in Scientific reports

Common and Rare Sequence Variants Influencing Tumor Biomarkers in Blood

by Olafsson, Sigurgeir, Alexandersson, Kristjan F, Gizurarson, Johann G K, Hauksdottir, Katrin, Gunnarsson, Orvar, Olafsson, Karl, Gudmundsson, Julius, Stacey, Simon N, Sveinbjornsson, Gardar, Saemundsdottir, Jona, Bjornsson, Einar S, Olafsson, Sigurdur, Bjornsson, Sigurdur, Orvar, Kjartan B, Vikingsson, Arnor, Geirsson, Arni J, Arinbjarnarson, Sturla, Bjornsdottir, Gyda, Thorgeirsson, Thorgeir E, Sigurdsson, Snaevar, Halldorsson, Gisli H, Magnusson, Olafur T, Masson, Gisli, Holm, Hilma, Jonsdottir, Ingileif, Sigurdardottir, Olof, Eyjolfsson, Gudmundur I, Olafsson, Isleifur, Sulem, Patrick, Thorsteinsdottir, Unnur, Jonsson, Thorvaldur, Rafnar, Thorunn, Gudbjartsson, Daniel F, Stefansson, Kari
Published in Cancer epidemiology, biomarkers & prevention

Sequence variant at 4q25 near PITX2 associates with appendicitis

by Kristjansson, Ragnar P, Benonisdottir, Stefania, Oddsson, Asmundur, Galesloot, Tessel E, Thorleifsson, Gudmar, Aben, Katja K, Davidsson, Olafur B, Jonsson, Stefan, Arnadottir, Gudny A, Jensson, Brynjar O, Walters, G Bragi, Sigurdsson, Jon K, Sigurdsson, Snaevar, Holm, Hilma, Arnar, David O, Thorgeirsson, Gudmundur, Alexiusdottir, Kristin, Jonsdottir, Ingileif, Thorsteinsdottir, Unnur, Kiemeney, Lambertus A, Jonsson, Thorvaldur, Gudbjartsson, Daniel F, Rafnar, Thorunn, Sulem, Patrick, Stefansson, Kari
Published in Scientific reports

Population-Based Study of Changing Breast Cancer Risk in Icelandic BRCA2 Mutation Carriers, 1920–2000

by Tryggvadottir, Laufey, Sigvaldason, Helgi, Olafsdottir, Gudridur H., Jonasson, Jon G., Jonsson, Thorvaldur, Tulinius, Hrafn, Eyfjörd, Jorunn E.
Published in JNCI : Journal of the National Cancer Institute

A population-based study on the familial aggregation of cutaneous malignant melanoma in Iceland

by Eldon, Bjarki Jonsson, Thorlacius, Steinunn, Jonsson, Thorvaldur, Jonasson, Jon Gunnlaugur, Kjartansson, Jens, Bodvarsson, Sigurdur, Steingrimsson, Eirikur, Rafnar, Thorunn
Published in European journal of cancer (1990)

Ancestry-Shift Refinement Mapping of the C6orf97-ESR1 Breast Cancer Susceptibility Locus: e1001029

by Stacey, Simon N, Sulem, Patrick, Zanon, Carlo, Gudjonsson, Sigurjon A, Thorleifsson, Gudmar, Helgason, Agnar, Jonasdottir, Aslaug, Besenbacher, Soren, Kostic, Jelena P, Fackenthal, James D, Huo, Dezheng, Adebamowo, Clement, Ogundiran, Temidayo, Olson, Janet E, Fredericksen, Zachary S, Wang, Xianshu, Look, Maxime P, Sieuwerts, Anieta M, Martens, John WM, Pajares, Isabel, Garcia-Prats, Maria D, Ramon-Cajal, Jose M, Juan, Ana de, Panadero, Angeles, Ortega, Eugenia, Aben, Katja KH, Vermeulen, Sita H, Asadzadeh, Fatemeh, Engelenburg, C Antonvan, Margolin, Sara, Shen, Chen-Yang, Wu, Pei-Ei, Försti, Asta, Lenner, Per, Henriksson, Roger, Johansson, Robert, Enquist, Kerstin, Hallmans, Göran, Jonsson, Thorvaldur, Sigurdsson, Helgi, Alexiusdottir, Kristin, Gudmundsson, Julius, Sigurdsson, Asgeir, Frigge, Michael L, Gudmundsson, Larus, Kristjansson, Kristleifur, Halldorsson, Bjarni V, Styrkarsdottir, Unnur, Gulcher, Jeffrey R, Hemminki, Kari, Lindblom, Annika, Kiemeney, Lambertus A, Mayordomo, Jose I, Foekens, John A, Couch, Fergus J, Olopade, Olufunmilayo I, Gudbjartsson, Daniel F, Thorsteinsdottir, Unnur, Rafnar, Thorunn, Johannsson, Oskar T, Stefansson, Kari
Published in PLoS genetics

GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures

by Styrkarsdottir, Unnur, Stefansson, Olafur A, Gunnarsdottir, Kristbjorg, Thorleifsson, Gudmar, Lund, Sigrun H, Stefansdottir, Lilja, Juliusson, Kristinn, Agustsdottir, Arna B, Zink, Florian, Halldorsson, Gisli H, Ivarsdottir, Erna V, Benonisdottir, Stefania, Jonsson, Hakon, Gylfason, Arnaldur, Norland, Kristjan, Trajanoska, Katerina, Boer, Cindy G, Southam, Lorraine, Leung, Jason C S, Tang, Nelson L S, Kwok, Timothy C Y, Lee, Jenny S W, Ho, Suzanne C, Byrjalsen, Inger, Center, Jacqueline R, Lee, Seung Hun, Koh, Jung-Min, Lohmander, L Stefan, Ho-Pham, Lan T, Nguyen, Tuan V, Eisman, John A, Woo, Jean, Leung, Ping-C, Loughlin, John, Zeggini, Eleftheria, Christiansen, Claus, Rivadeneira, Fernando, van Meurs, Joyce, Uitterlinden, Andre G, Mogensen, Brynjolfur, Jonsson, Helgi, Ingvarsson, Thorvaldur, Sigurdsson, Gunnar, Benediktsson, Rafn, Sulem, Patrick, Jonsdottir, Ingileif, Masson, Gisli, Holm, Hilma, Norddahl, Gudmundur L, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F, Stefansson, Kari
Published in Nature communications

Publisher Correction: GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures

by Styrkarsdottir, Unnur, Stefansson, Olafur A, Gunnarsdottir, Kristbjorg, Thorleifsson, Gudmar, Lund, Sigrun H, Stefansdottir, Lilja, Juliusson, Kristinn, Agustsdottir, Arna B, Zink, Florian, Halldorsson, Gisli H, Ivarsdottir, Erna V, Benonisdottir, Stefania, Jonsson, Hakon, Gylfason, Arnaldur, Norland, Kristjan, Trajanoska, Katerina, Boer, Cindy G, Southam, Lorraine, Leung, Jason C S, Tang, Nelson L S, Kwok, Timothy C Y, Lee, Jenny S W, Ho, Suzanne C, Byrjalsen, Inger, Center, Jacqueline R, Lee, Seung Hun, Koh, Jung-Min, Lohmander, L Stefan, Ho-Pham, Lan T, Nguyen, Tuan V, Eisman, John A, Woo, Jean, Leung, Ping-C, Loughlin, John, Zeggini, Eleftheria, Christiansen, Claus, Rivadeneira, Fernando, van Meurs, Joyce, Uitterlinden, Andre G, Mogensen, Brynjolfur, Jonsson, Helgi, Ingvarsson, Thorvaldur, Sigurdsson, Gunnar, Benediktsson, Rafn, Sulem, Patrick, Jonsdottir, Ingileif, Masson, Gisli, Holm, Hilma, Norddahl, Gudmundur L, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F, Stefansson, Kari
Published in Nature communications

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

by Zeggini, Eleftheria, Panoutsopoulou, Kalliope, Southam, Lorraine, Rayner, Nigel W, Day-Williams, Aaron G, Lopes, Margarida C, Boraska, Vesna, Esko, Tonu, Evangelou, Evangelos, Hoffman, Albert, Houwing-Duistermaat, Jeanine J, Ingvarsson, Thorvaldur, Jonsdottir, Ingileif, Jonnson, Helgi, Kerkhof, Hanneke J, Kloppenburg, Margreet, Bos, Steffan D, Mangino, Massimo, Metrustry, Sarah, Slagboom, P Eline, Thorleifsson, Gudmar, Raine, Emma V A, Ratnayake, Madhushika, Ricketts, Michelle, Beazley, Claude, Blackburn, Hannah, Bumpstead, Suzannah, Elliott, Katherine S, Hunt, Sarah E, Potter, Simon C, Shin, So-Youn, Yadav, Vijay K, Zhai, Guangju, Sherburn, Kate, Dixon, Kate, Arden, Elizabeth, Aslam, Nadim, Battley, Phillippa-kate, Carluke, Ian, Doherty, Sally, Gordon, Andrew, Joseph, John, Keen, Richard, Koller, Nicola C, Mitchell, Sheryl, O'Neill, Fiona, Paling, Ellen, Reed, Mike R, Rivadeneira, Fernando, Swift, Diane, Walker, Kirsten, Watkins, Bridget, Wheeler, Maggie, Birrell, Fraser, Ioannidis, John P A, Meulenbelt, Ingrid, Metspalu, Andres, Rai, Ashok, Salter, Donald, Stefansson, Kari, Stykarsdottir, Unnur, Uitterlinden, André G, van Meurs, Joyce B J, Chapman, Kay, Deloukas, Panos, Ollier, William E R, Wallis, Gillian A, Arden, Nigel, Carr, Andrew, Doherty, Michael, McCaskie, Andrew, Willkinson, J Mark, Ralston, Stuart H, Valdes, Ana M, Spector, Tim D, Loughlin, John
Published in The Lancet (British edition)

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

by Boer, Cindy G., Hatzikotoulas, Konstantinos, Southam, Lorraine, Stefánsdóttir, Lilja, Zhang, Yanfei, Coutinho de Almeida, Rodrigo, Wu, Tian T., Zheng, Jie, Hartley, April, Teder-Laving, Maris, Skogholt, Anne Heidi, Terao, Chikashi, Zengini, Eleni, Alexiadis, George, Barysenka, Andrei, Bjornsdottir, Gyda, Gabrielsen, Maiken E., Gilly, Arthur, Ingvarsson, Thorvaldur, Johnsen, Marianne B., Jonsson, Helgi, Kloppenburg, Margreet, Luetge, Almut, Lund, Sigrun H., Mägi, Reedik, Mangino, Massimo, Nelissen, Rob R.G.H.H., Shivakumar, Manu, Steinberg, Julia, Takuwa, Hiroshi, Thomas, Laurent F., Tuerlings, Margo, Babis, George C., Cheung, Jason Pui Yin, Kang, Jae Hee, Kraft, Peter, Lietman, Steven A., Samartzis, Dino, Slagboom, P. Eline, Stefansson, Kari, Thorsteinsdottir, Unnur, Tobias, Jonathan H., Uitterlinden, André G., Winsvold, Bendik, Zwart, John-Anker, Davey Smith, George, Sham, Pak Chung, Thorleifsson, Gudmar, Gaunt, Tom R., Morris, Andrew P., Valdes, Ana M., Tsezou, Aspasia, Cheah, Kathryn S.E., Ikegawa, Shiro, Hveem, Kristian, Esko, Tõnu, Wilkinson, J. Mark, Meulenbelt, Ingrid, Lee, Ming Ta Michael, van Meurs, Joyce B.J., Styrkársdóttir, Unnur, Zeggini, Eleftheria
Published in Cell

Large scale replication study of the association between HLA class II/BTNL2 variants and osteoarthritis of the knee in European-descent populations

by Valdes, Ana M, Styrkarsdottir, Unnur, Doherty, Michael, Morris, David L, Mangino, Massimo, Tamm, Agu, Doherty, Sally A, Kisand, Kalle, Kerna, Irina, Tamm, Ann, Wheeler, Margaret, Maciewicz, Rose A, Zhang, Weiya, Muir, Kenneth R, Dennison, Elaine M, Hart, Deborah J, Metrustry, Sarah, Jonsdottir, Ingileif, Jonsson, Gudbjorn F, Jonsson, Helgi, Ingvarsson, Thorvaldur, Cooper, Cyrus, Vyse, Timothy J, Spector, Tim D, Stefansson, Kari, Arden, Nigel K
Published in PloS one

Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits

by Styrkarsdottir, Unnur, Thorleifsson, Gudmar, Sulem, Patrick, Gudbjartsson, Daniel F, Sigurdsson, Asgeir, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Oddsson, Asmundur, Helgason, Agnar, Magnusson, Olafur T, Walters, G Bragi, Frigge, Michael L, Helgadottir, Hafdis T, Johannsdottir, Hrefna, Bergsteinsdottir, Kristin, Ogmundsdottir, Margret H, Center, Jacqueline R, Nguyen, Tuan V, Eisman, John A, Christiansen, Claus, Steingrimsson, Erikur, Jonasson, Jon G, Tryggvadottir, Laufey, Eyjolfsson, Gudmundur I, Theodors, Asgeir, Jonsson, Thorvaldur, Ingvarsson, Thorvaldur, Olafsson, Isleifur, Rafnar, Thorunn, Kong, Augustine, Sigurdsson, Gunnar, Masson, Gisli, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature (London)

Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus

by Hackinger, Sophie, Trajanoska, Katerina, Styrkarsdottir, Unnur, Zengini, Eleni, Steinberg, Julia, Ritchie, Graham R S, Hatzikotoulas, Konstantinos, Gilly, Arthur, Evangelou, Evangelos, Kemp, John P, Evans, David, Ingvarsson, Thorvaldur, Jonsson, Helgi, Thorsteinsdottir, Unnur, Stefansson, Kari, McCaskie, Andrew W, Brooks, Roger A, Wilkinson, Jeremy M, Rivadeneira, Fernando, Zeggini, Eleftheria
Published in Human molecular genetics

Genomewide Scan for Hand Osteoarthritis: A Novel Mutation in Matrilin-3

by Stefánsson, Stefán Einar, Jónsson, Helgi, Ingvarsson, Thorvaldur, Manolescu, Ileana, Jónsson, Hjörtur H., Ólafsdóttir, Guðbjörg, Pálsdóttir, Ebba, Stefánsdóttir, Gerður, Sveinbjörnsdóttir, Guðfinna, Frigge, Michael L., Kong, Augustine, Gulcher, Jeffrey R., Stefánsson, Kári
Published in American journal of human genetics

Using multivariable Mendelian randomization to estimate the causal effect of bone mineral density on osteoarthritis risk, independently of body mass index

by Hartley, April, Sanderson, Eleanor, Granell, Raquel, Paternoster, Lavinia, Zheng, Jie, Smith, George Davey, Southam, Lorraine, Hatzikotoulas, Konstantinos, Boer, Cindy G, van Meurs, Joyce, Zeggini, Eleftheria, Gregson, Celia L, Tobias, Jon H
Published in International journal of epidemiology

Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology

by Bjornsdottir, Gyda, Stefansdottir, Lilja, Thorleifsson, Gudmar, Sulem, Patrick, Norland, Kristjan, Ferkingstad, Egil, Oddsson, Asmundur, Zink, Florian, Lund, Sigrun H, Nawaz, Muhammad S, Bragi Walters, G, Skuladottir, Astros Th, Gudjonsson, Sigurjon A, Einarsson, Gudmundur, Halldorsson, Gisli H, Bjarnadottir, Valgerdur, Sveinbjornsson, Gardar, Helgadottir, Anna, Styrkarsdottir, Unnur, Gudmundsson, Larus J, Pedersen, Ole B, Hansen, Thomas Folkmann, Werge, Thomas, Banasik, Karina, Troelsen, Anders, Skou, Soren T, Thørner, Lise Wegner, Erikstrup, Christian, Nielsen, Kaspar Rene, Mikkelsen, Susan, Jonsdottir, Ingileif, Bjornsson, Aron, Olafsson, Ingvar H, Ulfarsson, Elfar, Blondal, Josep, Vikingsson, Arnor, Brunak, Soren, Ostrowski, Sisse R, Ullum, Henrik, Thorsteinsdottir, Unnur, Stefansson, Hreinn, Gudbjartsson, Daniel F, Thorgeirsson, Thorgeir E, Stefansson, Kari
Published in Nature communications