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Search Results - Hom,Darren L.
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Anilinodialkoxyquinazolines: Screening Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors for Potential Tumor Imaging Probes
by
VanBrocklin, Henry F
,
Lim, John K
,
Coffing, Stephanie L
,
Hom, Darren L
,
Negash, Kitaw
,
Ono, Michele Y
,
Gilmore, Jennifer L
,
Bryant, Ianthe
,
Riese, David J
Published in
Journal of medicinal chemistry
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Dialkoxyquinazolines: Screening Epidermal Growth Factor ReceptorTyrosine Kinase Inhibitors for Potential Tumor Imaging Probes
by
VanBrocklin, Henry F.
,
Lim, John K.
,
Coffing, Stephanie L.
,
Hom,Darren L.
,
Negash, Kitaw
,
Ono, Michele Y.
,
Hanrahan, Stephen M.
,
Taylor,Scott E.
,
Vanderpoel, Jennifer L.
,
Slavik, Sarah M.
,
Morris, Andrew B.
,
Riese II, David J.
Published in
Journal of medicinal chemistry
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Synthesis of [18F]fluoroanilines: Precursors to [18F]fluoroanilinoquinazolines
by
Vanbrocklin, Henry F.
,
O'Neil, James P.
,
Hom, Darren L.
,
Gibbs, Andrew R.
Published in
Journal of labelled compounds & radiopharmaceuticals
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Design of an orally efficacious hydroxyethylamine (HEA) BACE-1 inhibitor in a preclinical animal model
by
Truong, Anh P.
,
Tóth, Gergley
,
Probst, Gary D.
,
Sealy, Jennifer M.
,
Bowers, Simeon
,
Wone, David W.G.
,
Dressen, Darren
,
Hom, Roy K.
,
Konradi, Andrei W.
,
Sham, Hing L.
,
Wu, Jing
,
Peterson, Brian T.
,
Ruslim, Lany
,
Bova, Michael P.
,
Kholodenko, Dora
,
Motter, Ruth N.
,
Bard, Frédérique
,
Santiago, Pamela
,
Ni, Huifang
,
Chian, David
,
Soriano, Ferdie
,
Cole, Tracy
,
Brigham, Elizabeth F.
,
Wong, Karina
,
Zmolek, Wes
,
Goldbach, Erich
,
Samant, Bhushan
,
Chen, Linda
,
Zhang, Hongbing
,
Nakamura, David F.
,
Quinn, Kevin P.
,
Yednock, Ted A.
,
Sauer, John-Michael
Published in
Bioorganic & medicinal chemistry letters
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Design, synthesis, and structure–activity relationship of novel orally efficacious pyrazole/sulfonamide based dihydroquinoline γ-secretase inhibitors
by
Truong, Anh P.
,
Aubele, Danielle L.
,
Probst, Gary D.
,
Neitzel, Martin L.
,
Semko, Chris M.
,
Bowers, Simeon
,
Dressen, Darren
,
Hom, Roy K.
,
Konradi, Andrei W.
,
Sham, Hing L.
,
Garofalo, Albert W.
,
Keim, Pamela S.
,
Wu, Jing
,
Dappen, Michael S.
,
Wong, Karina
,
Goldbach, Erich
,
Quinn, Kevin P.
,
Sauer, John-Michael
,
Brigham, Elizabeth F.
,
Wallace, William
,
Nguyen, Lan
,
Hemphill, Susanna S.
,
Bova, Michael P.
,
Basi, Guriqbal
Published in
Bioorganic & medicinal chemistry letters
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Discovery of ( R )-4-Cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1 H -pyrazolo[4,3- c ]quinoline (ELND006) and ( R )-4-Cyclopropyl-8-fluoro-5-(6-(tri...
by
Probst, Gary
,
Aubele, Danielle L.
,
Bowers, Simeon
,
Dressen, Darren
,
Garofalo, Albert W.
,
Hom, Roy K.
,
Konradi, Andrei W.
,
Marugg, Jennifer L.
,
Mattson, Matthew N.
,
Neitzel, Martin L.
,
Semko, Chris M.
,
Sham, Hing L.
,
Smith, Jenifer
,
Sun, Minghua
,
Truong, Anh P.
,
Ye, Xiaocong M.
,
Xu, Ying-zi
,
Dappen, Michael S.
,
Jagodzinski, Jacek J.
,
Keim, Pamela S.
,
Peterson, Brian
,
Latimer, Lee H.
,
Quincy, David
,
Wu, Jing
,
Goldbach, Erich
,
Ness, Daniel K.
,
Quinn, Kevin P.
,
Sauer, John-Michael
,
Wong, Karina
,
Zhang, Hongbin
,
Zmolek, Wes
,
Brigham, Elizabeth F.
,
Kholodenko, Dora
,
Hu, Kang
,
Kwong, Grace T.
,
Lee, Michael
,
Liao, Anna
,
Motter, Ruth N.
,
Sacayon, Patricia
,
Santiago, Pamela
,
Willits, Christopher
,
Bard, Frédérique
,
Bova, Michael P.
,
Hemphill, Susanna S.
,
Nguyen, Lam
,
Ruslim, Lany
,
Tanaka, Kevin
,
Tanaka, Pearl
,
Wallace, William
,
Yednock, Ted A.
,
Basi, Guriqbal S.
Published in
Journal of medicinal chemistry
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Discovery of (R)‑4-Cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro‑1H‑pyrazolo[4,3‑c]quinoline (ELND006) and (R)‑4-Cyclopropyl-8-fluoro-5-(6-(trifluorome...
by
Probst, Gary
,
Aubele, Danielle L
,
Bowers, Simeon
,
Dressen, Darren
,
Garofalo, Albert W
,
Hom, Roy K
,
Konradi, Andrei W
,
Marugg, Jennifer L
,
Mattson, Matthew N
,
Neitzel, Martin L
,
Semko, Chris M
,
Sham, Hing L
,
Smith, Jenifer
,
Sun, Minghua
,
Truong, Anh P
,
Ye, Xiaocong M
,
Xu, Ying-zi
,
Dappen, Michael S
,
Jagodzinski, Jacek J
,
Keim, Pamela S
,
Peterson, Brian
,
Latimer, Lee H
,
Quincy, David
,
Wu, Jing
,
Goldbach, Erich
,
Ness, Daniel K
,
Quinn, Kevin P
,
Sauer, John-Michael
,
Wong, Karina
,
Zhang, Hongbin
,
Zmolek, Wes
,
Brigham, Elizabeth F
,
Kholodenko, Dora
,
Hu, Kang
,
Kwong, Grace T
,
Lee, Michael
,
Liao, Anna
,
Motter, Ruth N
,
Sacayon, Patricia
,
Santiago, Pamela
,
Willits, Christopher
,
Bard, Frédérique
,
Bova, Michael P
,
Hemphill, Susanna S
,
Nguyen, Lam
,
Ruslim, Lany
,
Tanaka, Kevin
,
Tanaka, Pearl
,
Wallace, William
,
Yednock, Ted A
,
Basi, Guriqbal S
Published in
Journal of medicinal chemistry
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Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: Structure–activity relationship of the aryl region
by
Probst, Gary D.
,
Bowers, Simeon
,
Sealy, Jennifer M.
,
Stupi, Brian
,
Dressen, Darren
,
Jagodzinska, Barbara M.
,
Aquino, Jose
,
Gailunas, Andrea
,
Truong, Anh P.
,
Tso, Luke
,
Xu, Ying-Zi
,
Hom, Roy K.
,
John, Varghese
,
Tung, Jay S.
,
Pleiss, Michael A.
,
Tucker, John A.
,
Konradi, Andrei W.
,
Sham, Hing L.
,
Jagodzinski, Jacek
,
Toth, Gergely
,
Brecht, Eric
,
Yao, Nanhua
,
Pan, Hu
,
Lin, May
,
Artis, Dean R.
,
Ruslim, Lany
,
Bova, Michael P.
,
Sinha, Sukanto
,
Yednock, Ted A.
,
Gauby, Shawn
,
Zmolek, Wes
,
Quinn, Kevin P.
,
Sauer, John-Michael
Published in
Bioorganic & medicinal chemistry letters
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Preparation and Optimization of a Series of 3-Carboxamido-5-phenacylaminopyrazole Bradykinin B1 Receptor Antagonists
by
Dressen, Darren
,
Garofalo, Albert W
,
Hawkinson, Jon
,
Hom, Dennis
,
Jagodzinski, Jacek
,
Marugg, Jennifer L
,
Neitzel, Martin L
,
Pleiss, Michael A
,
Szoke, Balazs
,
Tung, Jay S
,
Wone, David W. G
,
Wu, Jing
,
Zhang, Heather
Published in
Journal of medicinal chemistry
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Corrigendum to “Design, synthesis, and structure–activity relationship of novel orally efficacious pyrazole/sulfonamide based dihydroquinoline γ-secretase inhibitors” [Bioorg. Med....
by
Truong, Anh P.
,
Aubele, Danielle L.
,
Probst, Gary D.
,
Neitzel, Martin L.
,
Semko, Chris M.
,
Bowers, Simeon
,
Dressen, Darren
,
Hom, Roy K.
,
Konradi, Andrei W.
,
Sham, Hing L.
,
Garofalo, Albert W.
,
Keim, Pamela S.
,
Wu, Jing
,
Dappen, Michael S.
,
Wong, Karina
,
Goldbach, Erich
,
Quinn, Kevin P.
,
Sauer, John-Michael
,
Brigham, Elizabeth F.
,
Wallace, William
,
Nguyen, Lan
,
Hemphill, Susanna S.
,
Bova, Michael P.
,
Bard, Frédérique
,
Yednock, Ted A.
,
Basi, Guriqbal
Published in
Bioorganic & medicinal chemistry letters
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Design, synthesis, and structure-activity relationship of novel orally efficacious pyrazole/sulfonamide based dihydroquinoline g-secretase inhibitors
by
Truong, Anh P
,
Aubele, Danielle L
,
Probst, Gary D
,
Neitzel, Martin L
,
Semko, Chris M
,
Bowers, Simeon
,
Dressen, Darren
,
Hom, Roy K
,
Konradi, Andrei W
,
Sham, Hing L
,
Garofalo, Albert W
,
Keim, Pamela S
,
Wu, Jing
,
Dappen, Michael S
,
Wong, Karina
,
Goldbach, Erich
,
Quinn, Kevin P
,
Sauer, John-Michael
,
Brigham, Elizabeth F
,
Wallace, William
,
Nguyen, Lan
,
Hemphill, Susanna S
,
Bova, Michael P
,
Basi, Guriqbal
Published in
Bioorganic & medicinal chemistry letters
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Design, synthesis, and structure-activity relationship of novel orally efficacious pyrazole/sulfonamide based dihydroquinoline y-secretase inhibitors
by
TRUONG, Anh P
,
AUBELE, Danielle L
,
GAROFALO, Albert W
,
KEIM, Pamela S
,
JING WU
,
DAPPEN, Michael S
,
WONG, Marina
,
GOLDBACH, Erich
,
QUINN, Kevin P
,
SAUER, John-Michael
,
BRIGHAM, Elizabeth F
,
WALLACE, William
,
PROBST, Gary D
,
NGUYEN, Lan
,
HEMPHILL, Susanna S
,
BOVA, Michael P
,
BASI, Guriqbal
,
NEITZEL, Martin L
,
SEMKO, Chris M
,
BOWERS, Simeon
,
DRESSEN, Darren
,
HOM, Roy K
,
KONRADI, Andrei W
,
SHAM, Hing L
Published in
Bioorganic & medicinal chemistry letters
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