Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase

by Albrecht, Brian K, Harmange, Jean-Christophe, Bauer, David, Berry, Loren, Bode, Christiane, Boezio, Alessandro A, Chen, April, Choquette, Deborah, Dussault, Isabelle, Fridrich, Cary, Hirai, Satoko, Hoffman, Doug, Larrow, Jay F, Kaplan-Lefko, Paula, Lin, Jasmine, Lohman, Julia, Long, Alexander M, Moriguchi, Jodi, O’Connor, Anne, Potashman, Michele H, Reese, Monica, Rex, Karen, Siegmund, Aaron, Shah, Kavita, Shimanovich, Roman, Springer, Stephanie K, Teffera, Yohannes, Yang, Yajing, Zhang, Yihong, Bellon, Steven F
Published in Journal of medicinal chemistry

Discovery of (R)‑6-(1-(8-Fluoro-6-(1-methyl‑1H‑pyrazol-4-yl)-[1,2,4]triazolo[4,3‑a]pyridin-3-yl)ethyl)-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)‑one (AMG 337), a Potent and Select...

by Boezio, Alessandro A, Copeland, Katrina W, Rex, Karen, K. Albrecht, Brian, Bauer, David, Bellon, Steven F, Boezio, Christiane, Broome, Martin A, Choquette, Deborah, Coxon, Angela, Dussault, Isabelle, Hirai, Satoko, Lewis, Richard, Lin, Min-Hwa Jasmine, Lohman, Julia, Liu, Jingzhou, Peterson, Emily A, Potashman, Michele, Shimanovich, Roman, Teffera, Yohannes, Whittington, Douglas A, Vaida, Karina R, Harmange, Jean-Christophe
Published in Journal of medicinal chemistry

Campylobacter fetus Subspecies fetus Cellulitis Associated with Bacteremia in Debilitated Hosts

by Ichiyama, Satoshi, Hirai, Satoko, Minami, Tomoharu, Nishiyama, Yasunobu, Shimizu, Seiichi, Shimokata, Kaoru, Ohta, Michio
Published in Clinical infectious diseases

Discovery and optimization of potent and selective triazolopyridazine series of c-Met inhibitors

by Boezio, Alessandro A., Berry, Loren, Albrecht, Brian K., Bauer, David, Bellon, Steven F., Bode, Christiane, Chen, April, Choquette, Deborah, Dussault, Isabelle, Hirai, Satoko, Kaplan-Lefko, Paula, Larrow, Jay F., Lin, Min-Hwa Jasmine, Lohman, Julia, Potashman, Michele H., Rex, Karen, Santostefano, Michael, Shah, Kavita, Shimanovich, Roman, Springer, Stephanie K., Teffera, Yohannes, Yang, Yajing, Zhang, Yihong, Harmange, Jean-Christophe
Published in Bioorganic & medicinal chemistry letters

Corrigendum to “Discovery and optimization of potent and selective triazolopyridazine series of c-Met inhibitors” [Bioorg. Med. Chem. Lett. 19 (2009) 6307]

by Boezio, Alessandro A., Berry, Loren, Albrecht, Brian K., Bauer, David, Bellon, Steven F., Bode, Christiane, Chen, April, Choquette, Deborah, Dussault, Isabelle, Fang, Mei, Hirai, Satoko, Kaplan-Lefko, Paula, Larrow, Jay F., Lin, Min-Hwa Jasmine, Lohman, Julia, Potashman, Michele H., Qu, Yusheng, Rex, Karen, Santostefano, Michael, Shah, Kavita, Shimanovich, Roman, Springer, Stephanie K., Teffera, Yohannes, Yang, Yajing, Zhang, Yihong, Harmange, Jean-Christophe
Published in Bioorganic & medicinal chemistry letters

A descriptive analysis of producers' attitudes toward biotechnology: a five-state comparison

by Lawson, Michael E., Stover, Ronald, Hirai, Satoko
Published in Journal of foodservice

Agricultural Producers' Use of Genetically Modified Organisms

by Lawson, Michael E, Hess, Donna J, Hirai, Satoko
Published in The Great Plains sociologist

Sjögren's syndrome associated with thymoma

by Matsumoto, Yoshinari, Hirai, Satoko, Ohashi, Masaru, Imaizumi, Munehisa
Published in Journal of the American Academy of Dermatology

Selective Coexpression of Multiple Chemical Markers Defines Discrete Populations of Neocortical GABAergic Neurons

by Kubota, Yoshiyuki, Shigematsu, Naoki, Karube, Fuyuki, Sekigawa, Akio, Kato, Satoko, Yamaguchi, Noboru, Hirai, Yasuharu, Morishima, Mieko, Kawaguchi, Yasuo
Published in Cerebral cortex (New York, N.Y. 1991)

A selective cytotoxic adenovirus vector for concentration of pluripotent stem cells in human pluripotent stem cell-derived neural progenitor cells

by Hirai, Takamasa, Kono, Ken, Sawada, Rumi, Kuroda, Takuya, Yasuda, Satoshi, Matsuyama, Satoko, Matsuyama, Akifumi, Koizumi, Naoya, Utoguchi, Naoki, Mizuguchi, Hiroyuki, Sato, Yoji
Published in Scientific reports

A questionnaire survey on the efficacy of various treatments for dyskinetic cerebral palsy due to preterm bilirubin encephalopathy

by Kitai, Yukihiro, Hirai, Satori, Okuyama, Naomi, Hirotsune, Mika, Nishimoto, Shizuka, Mizutani, Satoshi, Okumura, Akihisa, Kumada, Satoko, Arai, Hiroshi
Published in Brain & development (Tokyo. 1979)

Development of information dissemination methods that contribute to improving maternal and child healthcare using social networking sites: a community-based cross-sectional study i...

by Ikeda, Sayaka, Ueda, Yutaka, Yagi, Asami, Taniguchi, Mariko, Matsuzaki, Satoko, Takiuchi, Tsuyoshi, Miyoshi, Ai, Arahori, Hitomi, Hirai, Kei, Kimura, Tadashi
Published in BMC public health

Withdrawal of thiopurines in Crohn’s disease treated with scheduled adalimumab maintenance: a prospective randomised clinical trial (DIAMOND2)

by Hisamatsu, Tadakazu, Kato, Shingo, Kunisaki, Reiko, Matsuura, Minoru, Nagahori, Masakazu, Motoya, Satoshi, Esaki, Motohiro, Fukata, Norimasa, Inoue, Satoko, Sugaya, Takeshi, Sakuraba, Hirotake, Hirai, Fumihito, Watanabe, Kenji, Kanai, Takanori, Naganuma, Makoto, Nakase, Hiroshi, Suzuki, Yasuo, Watanabe, Mamoru, Hibi, Toshifumi, Nojima, Masanori, Matsumoto, Takayuki
Published in Journal of gastroenterology

Efficacy of primary treatment with immunoglobulin plus ciclosporin for prevention of coronary artery abnormalities in patients with Kawasaki disease predicted to be at increased ri...

by Hamada, Hiromichi, Suzuki, Hiroyuki, Onouchi, Yoshihiro, Ebata, Ryota, Terai, Masaru, Fuse, Shigeto, Okajima, Yoshitomo, Kurotobi, Shunji, Hirai, Katsuki, Soga, Takashi, Ishiguchi, Yukiko, Okuma, Yoshiaki, Takada, Nobuyuki, Yanai, Masaaki, Sato, Junichi, Nakayashiro, Mami, Ayusawa, Mamoru, Yamamoto, Eiichi, Nomura, Yuichi, Hashimura, Yuya, Ouchi, Kazunobu, Takatsuki, Shinichi, Hirono, Keiichi, Ariga, Tadashi, Higaki, Takashi, Otsuki, Akio, Terauchi, Moe, Aoyagi, Reiko, Sato, Takatoshi, Fujii, Yasuhisa, Fujiwara, Tadami, Hata, Akira, Hamada, Hiromichi, Honda, Takafumi, Yasukawa, Kumi, Hirai, Katsuki, Takahiro, Nishihara, Soga, Takashi, Yajima, Hideoki, Ooto, Hideyasu, Umeda, You, Suzuki, Hiroyuki, Kakimoto, Nobuyuki, Ishiguchi, Yukiko, Kamada, Masahiro, Okuma, Yoshiaki, Takada, Nobuyuki, Suwabe, Shinichi, Yanai, Masaaki, Ueno, Yasushi, Nishi, Natsuko, Sato, Junichi, Saito, Yuuko, Kitani, Yutaka, Nakayashiro, Mami, Nabeshima, Taisuke, Nakamura, Takahiro, Komori, Akiko, Kato, Masataka, Ebata, Ryota, Saito, Naoki, Okunushi, Kentaro, Kobayashi, Hironobu, Yamamoto, Eiichi, Nakano, Takeshi, Nomura, Yuichi, Masuda, Kiminori, Hashimura, Yuya, Minami, Hirotaka, Uchiyama, Takamichi, Okizuka, You, Ouchi, Kazunobu, Ohno, Naoki, Ogita, Satoko, Masuda, Hiroshi, Ono, Hiroshi, Ishiguro, Akira, Takatsuki, Shinichi, Saji, Tsutomu, Ichida, Fukiko, Hirono, Keiichi, Ozawa, Sayaka, Ariga, Tadashi, Takeda, Atsuhito, Izumi, Gaku, Higaki, Takashi, Otsuki, Akio, Hata, Akira, Hanaoka, Hideki, Terai, Masaru, Onouchi, Yoshihiro, Terauchi, Moe, Fujii, Yasuhisa, Sato, Takatoshi, Aoyagi, Reiko, Hanawa, Michiko, Fujiwara, Tadami, Fuse, Shigeto, Okajima, Yoshitomo, Kurotobi, Shunji
Published in The Lancet (British edition)

Corticotropin‐releasing hormone‐binding protein is up‐regulated by brain‐derived neurotrophic factor and is secreted in an activity‐dependent manner in rat cerebral cortical neuron...

by Adachi, Naoki, Suzuki, Shingo, Matsuoka, Hidetada, Fushimi, Satoko, Ono, Junichiro, Ohta, Ken‐ichi, Hirai, Yohei, Miki, Takanori, Koshimizu, Hisatsugu
Published in Journal of neurochemistry

Prognostic Impact of CD163+ Macrophages in Tumor Stroma and CD8+ T-Cells in Cancer Cell Nests in Invasive Extrahepatic Bile Duct Cancer

by Miura, Takuya, Yoshizawa, Tadashi, Hirai, Hideaki, Seino, Hiroko, Morohashi, Satoko, Wu, Yunyan, Wakiya, Taiichi, Kimura, Norihisa, Kudo, Daisuke, Ishido, Keinosuke, Toyoki, Yoshikazu, Kijima, Hiroshi, Hakamada, Kenichi
Published in Anticancer research

A CDC42EP4/septin-based perisynaptic glial scaffold facilitates glutamate clearance

by Ageta-Ishihara, Natsumi, Yamazaki, Maya, Konno, Kohtarou, Nakayama, Hisako, Abe, Manabu, Hashimoto, Kenji, Nishioka, Tomoki, Kaibuchi, Kozo, Hattori, Satoko, Miyakawa, Tsuyoshi, Tanaka, Kohichi, Huda, Fathul, Hirai, Hirokazu, Hashimoto, Kouichi, Watanabe, Masahiko, Sakimura, Kenji, Kinoshita, Makoto
Published in Nature communications

Is bowel preparation necessary for early colonoscopy in patients with suspected colonic diverticular bleeding?: A multicenter retrospective study with propensity score matching ana...

by Gonai, Takahiro, Toya, Yosuke, Kudara, Norihiko, Abe, Keinosuke, Sawaguchi, Sera, Fujiwara, Takao, Eizuka, Makoto, Hirai, Minami, Miura, Manami, Urushikubo, Jun, Yamada, Shun, Kumei, Tomo, Yamaguchi, Satoko, Sugai, Kyohei, Asakura, Kensuke, Orikasa, Shunsuke, Matsumoto, Takayuki
Published in DEN open

In-straw Cryoprotectant Dilution for Bovine Embryos Vitrified Using Cryotop

by INABA, Yasushi, AIKAWA, Yoshio, HIRAI, Tomokazu, HASHIYADA, Yutaka, YAMANOUCHI, Tadayuki, MISUMI, Koji, OHTAKE, Masaki, SOMFAI, Tamas, KOBAYASHI, Shuji, SAITO, Norio, MATOBA, Satoko, KONISHI, Kazuyuki, IMAI, Kei
Published in Journal of Reproduction and Development

Effect of dietary fatty acid and micronutrient intake/energy ratio on serum diamine oxidase activity in healthy women

by Miyoshi, Makoto, M.T., Ph.D, Ueno, Manami, R.D, Matsuo, Mari, R.D, Hamada, Yasuhiro, M.D., Ph.D, Takahashi, Michiko, M.D., Ph.D, Yamamoto, Masashi, M.D., Ph.D, Yamamoto, Ikuko, R.D., M.S, Mikajiri, Reiko, R.D., M.S, Tabuchi, Satoko, R.D., M.S, Wakida, Kumiko, R.D, Yamanishi, Misa, R.D, Hirai, Midori, P.C., Ph.D, Usami, Makoto, M.D., Ph.D
Published in Nutrition (Burbank, Los Angeles County, Calif.)