Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling

by Ketterer, Stephanie, Mitschke, Julia, Ketscher, Anett, Schlimpert, Manuel, Reichardt, Wilfried, Baeuerle, Natascha, Hess, Maria Elena, Metzger, Patrick, Boerries, Melanie, Peters, Christoph, Kammerer, Bernd, Brummer, Tilman, Steinberg, Florian, Reinheckel, Thomas
Published in Nature communications

MIRACUM-Pipe: An Adaptable Pipeline for Next-Generation Sequencing Analysis, Reporting, and Visualization for Clinical Decision Making

by Metzger, Patrick, Hess, Maria Elena, Blaumeiser, Andreas, Pauli, Thomas, Schipperges, Vincent, Mertes, Ralf, Christoph, Jan, Unberath, Philipp, Reimer, Niklas, Scheible, Raphael, Illert, Anna L, Busch, Hauke, Andrieux, Geoffroy, Boerries, Melanie
Published in Cancers

Automated library preparation for whole genome sequencing by centrifugal microfluidics

by Hess, Jacob Friedrich, Hess, Maria Elena, Zengerle, Roland, Paust, Nils, Boerries, Melanie, Hutzenlaub, Tobias
Published in Analytica chimica acta

RNA interference screens discover proteases as synthetic lethal partners of PI3K inhibition in breast cancer cells

by Hölzen, Lena, Mitschke, Jan, Schönichen, Claudia, Hess, Maria Elena, Ehrenfeld, Sophia, Boerries, Melanie, Miething, Cornelius, Brummer, Tilman, Reinheckel, Thomas
Published in Theranostics

Transitioning the Molecular Tumor Board from Proof of Concept to Clinical Routine: A German Single-Center Analysis

by Hoefflin, Rouven, Lazarou, Adriana, Hess, Maria Elena, Reiser, Meike, Wehrle, Julius, Metzger, Patrick, Frey, Anna Verena, Becker, Heiko, Aumann, Konrad, Berner, Kai, Boeker, Martin, Buettner, Nico, Dierks, Christine, Duque-Afonso, Jesus, Eisenblaetter, Michel, Erbes, Thalia, Fritsch, Ralph, Ge, Isabell Xiang, Geißler, Anna-Lena, Grabbert, Markus, Heeg, Steffen, Heiland, Dieter Henrik, Hettmer, Simone, Kayser, Gian, Keller, Alexander, Kleiber, Anita, Kutilina, Alexandra, Mehmed, Leman, Meiss, Frank, Poxleitner, Philipp, Rawluk, Justyna, Ruf, Juri, Schäfer, Henning, Scherer, Florian, Shoumariyeh, Khalid, Tzschach, Andreas, Peters, Christoph, Brummer, Tilman, Werner, Martin, Duyster, Justus, Lassmann, Silke, Miething, Cornelius, Boerries, Melanie, Illert, Anna L, von Bubnoff, Nikolas
Published in Cancers

The ROCEEH Out of Africa Database (ROAD): A large-scale research database serves as an indispensable tool for human evolutionary studies

by Kandel, Andrew W, Sommer, Christian, Kanaeva, Zara, Bolus, Michael, Bruch, Angela A, Groth, Claudia, Haidle, Miriam N, Hertler, Christine, Heß, Julia, Malina, Maria, Märker, Michael, Hochschild, Volker, Mosbrugger, Volker, Schrenk, Friedemann, Conard, Nicholas J
Published in PloS one

Multimessenger observations of a flaring blazar coincident with high-energy neutrino IceCube-170922A

by Ackermann, Markus, Ansseau, Isabelle, Anton, Gisela, Tjus, Julia, Besson, David, Dave, Pranav, DeYoung, Ty, Dunkman, Matt, Felde, John, Hoinka, Tobias, Jacobi, Emanuel, Kelley, John, Koskinen, Jason, Leonard, Kayla, Luszczak, William, Meures, Thomas, Neer, Garrett, Nygren, Dave, O'Sullivan, Erin, Plum, Matthias, Reimann, Rene, Rott, Carsten, Ryckbosch, Dirk, Rysewyk, Devyn, Sandroos, Joakim, Tobin, Moriah, Tosi, Delia, Williams, Dawn, Baldini, Luca, Ballet, Jean, Barbiellini, Guido, Bastieri, Denis, Bregeon, Johan, Charles, Eric, Cutini, Sara, de Palma, Francesco, Digel, Seth, Giordano, Francesco, Grondin, Marie-Hélène, Krauss, Felicia, Lubrano, Pasquale, Malyshev, Dmitry, Porter, Troy, Principe, Giacomo, Reimer, Anita, Barres de Almeida, Ulisses, González, Josefa Becerra, Colak, Sidika Merve, Di Pierro, Federico, Fidalgo, David, Herrera, Javier, Hrupec, Dario, Minev, Milen, Moralejo, Abelardo, Nilsson, Kari, Pedaletti, Giovanna, Saito, Takayuki, Sitarek, Julian, Ward, John E., Donnarumma, Imma, Ferrari, Attilio, Trois, Alessio, Vercellone, Stefano, Arteaga Velázquez, Juan Carlos, Bernal, Abel, Caballero Mora, Karen S., Castillo Maldonado, Mario Alberto, Coutiño de León, Sara, DuVernois, Michael, Lee, William, Martinez Castellanos, Israel, González, Daniel Rosa, Rosenberg, Matthew, Ruiz-Velasco, Edna, Brun, F., Büchele, M., Casanova, S., Grondin, M.-H., Hoischen, C., Jankowsky, F., Lorentz, M., Lypova, I., Moderski, R., Rudak, B., Sasaki, M., Schulz, A., Taylor, A. M., van Eldik, C., Savchenko, V., Kuulkers, E., Mereghetti, S., Archer, Avery, Finley, John, Fortson, Lucy, Otte, Adam, Pohl, Martin, Popkow, Alexis, Weinstein, Amanda, Wells, Rita, Miller-Jones, James
Published in Science (American Association for the Advancement of Science)

Micronutrient deficiencies among preschool-aged children and women of reproductive age worldwide: a pooled analysis of individual-level data from population-representative surveys

by Stevens, Gretchen A, Beal, Ty, Mbuya, Mduduzi N N, Luo, Hanqi, Neufeld, Lynnette M, Addo, O Yaw, Adu-Afarwuah, Seth, Alayón, Silvia, Bhutta, Zulfiqar, Brown, Kenneth H, Jefferds, Maria Elena, Engle-Stone, Reina, Fawzi, Wafaie, Hess, Sonja Y, Johnston, Robert, Katz, Joanne, Krasevec, Julia, McDonald, Christine M, Mei, Zuguo, Osendarp, Saskia, Paciorek, Christopher J, Petry, Nicolai, Pfeiffer, Christine M, Ramirez-Luzuriaga, Maria J, Rogers, Lisa M, Rohner, Fabian, Sethi, Vani, Suchdev, Parminder S, Tessema, Masresha, Villapando, Salvador, Wieringa, Frank T, Williams, Anne M, Woldeyahannes, Meseret, Young, Melissa F
Published in The Lancet global health

Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans

by George, Parakkal Jovvian, Hess, Jessica A, Jain, Sonia, Patton, John B, Zhan, Tingting, Tricoche, Nancy, Zhan, Bin, Bottazzi, Maria Elena, Hotez, Peter J, Abraham, David, Lustigman, Sara
Published in PLoS neglected tropical diseases

Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies

by Broce, Iris, Karch, Celeste M, Wen, Natalie, Fan, Chun C, Wang, Yunpeng, Tan, Chin Hong, Kouri, Naomi, Ross, Owen A, Höglinger, Günter U, Muller, Ulrich, Hardy, John, Momeni, Parastoo, Hess, Christopher P, Dillon, William P, Miller, Zachary A, Bonham, Luke W, Rabinovici, Gil D, Rosen, Howard J, Schellenberg, Gerard D, Franke, Andre, Karlsen, Tom H, Veldink, Jan H, Ferrari, Raffaele, Yokoyama, Jennifer S, Miller, Bruce L, Andreassen, Ole A, Dale, Anders M, Desikan, Rahul S, Sugrue, Leo P
Published in PLoS medicine

Phase III Trial of Ursodeoxycholic Acid To Prevent Colorectal Adenoma Recurrence

by Alberts, David S., Martínez, María Elena, Hess, Lisa M., Einspahr, Janine G., Green, Sylvan B., Bhattacharyya, A. K., Guillen, Jose, Krutzsch, Mary, Batta, Ashok K., Salen, Gerald, Fales, Liane, Koonce, Kris, Parish, Dianne, Clouser, Mary, Roe, Denise, Lance, Peter
Published in JNCI : Journal of the National Cancer Institute

The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice

by Hess, Jessica A, Zhan, Bin, Torigian, April R, Patton, John B, Petrovsky, Nikolai, Zhan, Tingting, Bottazzi, Maria Elena, Hotez, Peter J, Klei, Thomas R, Lustigman, Sara, Abraham, David
Published in PLoS neglected tropical diseases

Multicenter Study of Long-Term Outcomes and Quality of Life in PHACE Syndrome after Age 10

by Braun, Mitchell, Frieden, Ilona J., Siegel, Dawn H., George, Elizabeth, Hess, Christopher P., Fox, Christine K., Chamlin, Sarah L., Drolet, Beth A., Metry, Denise, Pope, Elena, Powell, Julie, Holland, Kristen, Ulschmid, Caden, Liang, Marilyn G., Barry, Kelly K., Ho, Tina, Cotter, Chantal, Baselga, Eulalia, Bosquez, David, Jain, Surabhi Neerendranath, Bui, Jordan K., Lara-Corrales, Irene, Funk, Tracy, Small, Alison, Baghoomian, Wenelia, Yan, Albert C., Treat, James R., Hogrogian, Griffin Stockton, Huang, Charles, Haggstrom, Anita, List, Mary, McCuaig, Catherine C., Barrio, Victoria, Mancini, Anthony J., Lawley, Leslie P., Grunnet-Satcher, Kerrie, Horii, Kimberly A., Newell, Brandon, Nopper, Amy, Garzon, Maria C., Scollan, Margaret E., Mathes, Erin F.
Published in The Journal of pediatrics

Adjuvanted Fusion Protein Vaccine Induces Durable Immunity to Onchocerca volvulus in Mice and Non-Human Primates

by Ryan, Nathan M, Hess, Jessica A, Robertson, Erica J, Tricoche, Nancy, Turner, Cheri, Davis, Jenn, Petrovsky, Nikolai, Ferguson, Melissa, Rinaldi, William J, Wong, Valerie M, Shimada, Ayako, Zhan, Bin, Bottazzi, Maria Elena, Makepeace, Benjamin L, Gray, Sean A, Carter, Darrick, Lustigman, Sara, Abraham, David
Published in Vaccines (Basel)

Association between age at disease onset of anti-neutrophil cytoplasmic antibody–associated vasculitis and clinical presentation and short-term outcomes

by Monti, Sara, Craven, Anthea, Klersy, Catherine, Montecucco, Carlomaurizio, Caporali, Roberto, Watts, Richard, Merkel, Peter A, Luqmani, Raashid
Published in Rheumatology (Oxford, England)

Epcoritamab SC Monotherapy Leads to Deep and Durable Responses in Patients with Relapsed or Refractory Follicular Lymphoma: First Data Disclosure from the Epcore NHL-1 Follicular L...

by Linton, Kim, Jurczak, Wojciech, Lugtenburg, Pieternella, Gyan, Emmanuel, Sureda Balari, Anna Maria, Christensen, Jacob Haaber, Hess, Brian, Tilly, Hervé, Cordoba, Raul, Lewis, David, Okada, Craig, Hutchings, Martin, Clausen, Michael Roost, Vitolo, Umberto, Cochrane, Tara, Leppa, Sirpa, Chamuleau, Martine E.D., Conlon, Rebekah, Favaro, Elena, Gernhardt, Diana, Altintas, Isil, Liu, Yan, Thieblemont, Catherine
Published in Blood

Stroke in Children With Posterior Fossa Brain Malformations, Hemangiomas, Arterial Anomalies, Coarctation of the Aorta and Cardiac Defects, and Eye Abnormalities (PHACE) Syndrome:...

by SIEGEL, Dawn H, TEFFT, Kimberly A, KEITH, Phillip, GARZON, Maria, HESS, Christopher, FRIEDEN, Ilona J, FULLERTON, Heather J, DROLET, Beth A, KELLY, Teresa, JOHNSON, Craig, METRY, Denise, BURROWS, Patricia, POPE, Elena, CORDISCO, Maria, HOLLAND, Kristen E, MAHESHWARI, Mohit
Published in Stroke (1970)

Onchocerca volvulus bivalent subunit vaccine induces protective immunity in genetically diverse collaborative cross recombinant inbred intercross mice

by Ryan, Nathan M, Hess, Jessica A, de Villena, Fernando Pardo-Manuel, Leiby, Benjamin E, Shimada, Ayako, Yu, Lei, Yarmahmoodi, Amir, Petrovsky, Nikolai, Zhan, Bin, Bottazzi, Maria Elena, Makepeace, Benjamin L, Lustigman, Sara, Abraham, David
Published in npj vaccines

Vaccines to combat river blindness: expression, selection and formulation of vaccines against infection with Onchocerca volvulus in a mouse model

by Hess, Jessica A., Zhan, Bin, Bonne-Année, Sandra, Deckman, Jessica M., Bottazzi, Maria Elena, Hotez, Peter J., Klei, Thomas R., Lustigman, Sara, Abraham, David
Published in International journal for parasitology

Delivery of progenitors to the thymus limits T-lineage reconstitution after bone marrow transplantation

by Zlotoff, Daniel A., Zhang, Shirley L., De Obaldia, Maria Elena, Hess, Paul R., Todd, Sarah P., Logan, Theodore D., Bhandoola, Avinash
Published in Blood