Extended interval BNT162b2 vaccination enhances peak antibody generation

by Parry, Helen, Bruton, Rachel, Stephens, Christine, Bentley, Christopher, Brown, Kevin, Amirthalingam, Gayatri, Hallis, Bassam, Otter, Ashley, Zuo, Jianmin, Moss, Paul
Published in npj vaccines

Comparison of rhesus and cynomolgus macaques as an infection model for COVID-19

by Salguero, Francisco J, White, Andrew D, Slack, Gillian S, Fotheringham, Susan A, Bewley, Kevin R, Gooch, Karen E, Longet, Stephanie, Humphries, Holly E, Watson, Robert J, Hunter, Laura, Ryan, Kathryn A, Hall, Yper, Sibley, Laura, Sarfas, Charlotte, Allen, Lauren, Aram, Marilyn, Brunt, Emily, Brown, Phillip, Buttigieg, Karen R, Cavell, Breeze E, Cobb, Rebecca, Coombes, Naomi S, Darby, Alistair, Daykin-Pont, Owen, Elmore, Michael J, Garcia-Dorival, Isabel, Gkolfinos, Konstantinos, Godwin, Kerry J, Gouriet, Jade, Halkerston, Rachel, Harris, Debbie J, Hender, Thomas, Ho, Catherine M K, Kennard, Chelsea L, Knott, Daniel, Leung, Stephanie, Lucas, Vanessa, Mabbutt, Adam, Morrison, Alexandra L, Nelson, Charlotte, Ngabo, Didier, Paterson, Jemma, Penn, Elizabeth J, Pullan, Steve, Taylor, Irene, Tipton, Tom, Thomas, Stephen, Tree, Julia A, Turner, Carrie, Vamos, Edith, Wand, Nadina, Wiblin, Nathan R, Charlton, Sue, Dong, Xiaofeng, Hallis, Bassam, Pearson, Geoffrey, Rayner, Emma L, Nicholson, Andrew G, Funnell, Simon G, Hiscox, Julian A, Dennis, Mike J, Gleeson, Fergus V, Sharpe, Sally, Carroll, Miles W
Published in Nature communications

Differential immunogenicity of BNT162b2 or ChAdOx1 vaccines after extended-interval homologous dual vaccination in older people

by Parry, Helen, Bruton, Rachel, Stephens, Christine, Brown, Kevin, Amirthalingam, Gayatri, Otter, Ashley, Hallis, Bassam, Zuo, Jianmin, Moss, Paul
Published in Immunity & ageing

Dose-dependent response to infection with SARS-CoV-2 in the ferret model and evidence of protective immunity

by Ryan, Kathryn A, Bewley, Kevin R, Fotheringham, Susan A, Slack, Gillian S, Brown, Phillip, Hall, Yper, Wand, Nadina I, Marriott, Anthony C, Cavell, Breeze E, Tree, Julia A, Allen, Lauren, Aram, Marilyn J, Bean, Thomas J, Brunt, Emily, Buttigieg, Karen R, Carter, Daniel P, Cobb, Rebecca, Coombes, Naomi S, Findlay-Wilson, Steve J, Godwin, Kerry J, Gooch, Karen E, Gouriet, Jade, Halkerston, Rachel, Harris, Debbie J, Hender, Thomas H, Humphries, Holly E, Hunter, Laura, Ho, Catherine M K, Kennard, Chelsea L, Leung, Stephanie, Longet, Stephanie, Ngabo, Didier, Osman, Karen L, Paterson, Jemma, Penn, Elizabeth J, Pullan, Steven T, Rayner, Emma, Skinner, Oliver, Steeds, Kimberley, Taylor, Irene, Tipton, Tom, Thomas, Stephen, Turner, Carrie, Watson, Robert J, Wiblin, Nathan R, Charlton, Sue, Hallis, Bassam, Hiscox, Julian A, Funnell, Simon, Dennis, Mike J, Whittaker, Catherine J, Catton, Michael G, Druce, Julian, Salguero, Francisco J, Carroll, Miles W
Published in Nature communications

mRNA vaccination in people over 80 years of age induces strong humoral immune responses against SARS-CoV-2 with cross neutralization of P.1 Brazilian variant

by Parry, Helen, Tut, Gokhan, Bruton, Rachel, Faustini, Sian, Stephens, Christine, Saunders, Philip, Bentley, Christopher, Hilyard, Katherine, Brown, Kevin, Amirthalingam, Gayatri, Charlton, Sue, Leung, Stephanie, Chiplin, Emily, Coombes, Naomi S, Bewley, Kevin R, Penn, Elizabeth J, Rowe, Cathy, Otter, Ashley, Watts, Rosie, D'Arcangelo, Silvia, Hallis, Bassam, Makin, Andrew, Richter, Alex, Zuo, Jianmin, Moss, Paul
Published in eLife

Serological surveillance of SARS-CoV-2: Six-month trends and antibody response in a cohort of public health workers

by Harris, Ross J., Whitaker, Heather J., Andrews, Nick J., Aiano, Felicity, Amin-Chowdhury, Zahin, Flood, Jessica, Borrow, Ray, Linley, Ezra, Ahmad, Shazaad, Stapley, Lorraine, Hallis, Bassam, Amirthalingam, Gayatri, Höschler, Katja, Parker, Ben, Horsley, Alex, Brooks, Timothy J.G., Brown, Kevin E., Ramsay, Mary E., Ladhani, Shamez N.
Published in The Journal of infection

A phase IV, multi-centre, randomized clinical trial comparing two pertussis-containing vaccines in pregnant women in England and vaccine responses in their infants

by Jones, Christine Elizabeth, Calvert, Anna, Southern, Jo, Matheson, Mary, Andrews, Nick, Khalil, Asma, Cuthbertson, Hannah, Hallis, Bassam, England, Anna, Heath, Paul T, Miller, Elizabeth
Published in BMC medicine

Monkeypox virus-infected individuals mount comparable humoral immune responses as Smallpox-vaccinated individuals

by Otter, Ashley D, Jones, Scott, Hicks, Bethany, Bailey, Daniel, Callaby, Helen, Houlihan, Catherine, Rampling, Tommy, Gordon, Nicola Claire, Selman, Hannah, Satheshkumar, Panayampalli S, Townsend, Michael, Mehta, Ravi, Pond, Marcus, Jones, Rachael, Wright, Deborah, Oeser, Clarissa, Tonge, Simon, Linley, Ezra, Hemingway, Georgia, Coleman, Tom, Millward, Sebastian, Lloyd, Aaron, Damon, Inger, Brooks, Tim, Vipond, Richard, Rowe, Cathy, Hallis, Bassam
Published in Nature communications

Detection of SARS-CoV-2 BA.2.86 by lateral flow devices

by Bown, Abbie, Sweed, Angela, Catton, Matthew, Nelthorpe-Cowne, Joshua, Conti-Frith, Hermione, Elderfield, Ruth, Terrey, Jacob, Abib, Hamsa, Lui, Caleb, Fisher, Ella, Bewley, Kevin R, Coombes, Naomi S, Robinson, Donna, Agrawal, Somya, Hallis, Bassam, Blandford, Edward, Fowler, Tom, Williamson, Deborah A, Vipond, Richard
Published in International journal of infectious diseases

Assessment of the Biological Impact of SARS-CoV-2 Genetic Variation Using an Authentic Virus Neutralisation Assay with Convalescent Plasma, Vaccinee Sera, and Standard Reagents

by Coombes, Naomi S, Bewley, Kevin R, Le Duff, Yann, Hurley, Matthew, Smith, Lauren J, Weldon, Thomas M, Osman, Karen, Pullan, Steven, Berry, Neil, Hallis, Bassam, Charlton, Sue, Hall, Yper, Funnell, Simon G P
Published in Viruses

Interlaboratory comparison of a multiplex immunoassay that measures human serum IgG antibodies against six-group B streptococcus polysaccharides

by Le Doare, Kirsty, Gaylord, Michelle A, Anderson, Annaliesa S, Andrews, Nick, Baker, Carol J, Bolcen, Shanna, Felek, Arif, Giardina, Peter C, Grube, Christopher D, Hall, Tom, Hallis, Bassam, Izu, Alane, Madhi, Shabir A, Maniatis, Pete, Matheson, Mary, Mawas, Fatme, McKeen, Andrew, Rhodes, Julia, Alston, Bailey, Patel, Palak, Schrag, Stephanie, Simon, Raphael, Tan, Charles Y, Taylor, Stephen, Kwatra, Gaurav, Gorringe, Andrew
Published in Human vaccines & immunotherapeutics

Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir

by Marriott, Anthony C, Dove, Brian K, Whittaker, Catherine J, Bruce, Christine, Ryan, Kathryn A, Bean, Thomas J, Rayner, Emma, Pearson, Geoff, Taylor, Irene, Dowall, Stuart, Plank, Jenna, Newman, Edmund, Barclay, Wendy S, Dimmock, Nigel J, Easton, Andrew J, Hallis, Bassam, Silman, Nigel J, Carroll, Miles W
Published in PloS one

Influenza A Virus Challenge Models in Cynomolgus Macaques Using the Authentic Inhaled Aerosol and Intra-Nasal Routes of Infection

by Marriott, Anthony C, Dennis, Mike, Kane, Jennifer A, Gooch, Karen E, Hatch, Graham, Sharpe, Sally, Prevosto, Claudia, Leeming, Gail, Zekeng, Elsa-Gayle, Staples, Karl J, Hall, Graham, Ryan, Kathryn A, Bate, Simon, Moyo, Nathifa, Whittaker, Catherine J, Hallis, Bassam, Silman, Nigel J, Lalvani, Ajit, Wilkinson, Tom M, Hiscox, Julian A, Stewart, James P, Carroll, Miles W
Published in PloS one

Severity of heterosubtypic influenza virus infection in ferrets is reduced by live attenuated influenza vaccine

by Marriott, Anthony C, Gooch, Karen E, Brown, Phillip J, Ryan, Kathryn A, Jones, Nicola J, Merredew, Natasha, Wiblin, Nathan, Dibben, Oliver, Bright, Helen, Hallis, Bassam, Whittaker, Catherine J, Carroll, Miles W
Published in npj vaccines

Cloned defective interfering influenza virus protects ferrets from pandemic 2009 influenza A virus and allows protective immunity to be established

by Dimmock, Nigel J, Dove, Brian K, Scott, Paul D, Meng, Bo, Taylor, Irene, Cheung, Linda, Hallis, Bassam, Marriott, Anthony C, Carroll, Miles W, Easton, Andrew J
Published in PloS one

Comparison of the protection of ferrets against pandemic 2009 influenza A virus (H1N1) by 244 DI influenza virus and oseltamivir

by Dimmock, Nigel J., Dove, Brian K., Meng, Bo, Scott, Paul D., Taylor, Irene, Cheung, Linda, Hallis, Bassam, Marriott, Anthony C., Carroll, Miles W., Easton, Andrew J.
Published in Antiviral research

Whole genome protein microarrays for serum profiling of immunodominant antigens of Bacillus anthracis

by Kempsell, Karen E, Kidd, Stephen P, Lewandowski, Kuiama, Elmore, Michael J, Charlton, Sue, Yeates, Annemarie, Cuthbertson, Hannah, Hallis, Bassam, Altmann, Daniel M, Rogers, Mitch, Wattiau, Pierre, Ingram, Rebecca J, Brooks, Tim, Vipond, Richard
Published in Frontiers in microbiology

Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera

by Zhou, Daming, Dejnirattisai, Wanwisa, Supasa, Piyada, Liu, Chang, Mentzer, Alexander J., Ginn, Helen M., Zhao, Yuguang, Duyvesteyn, Helen M.E., Tuekprakhon, Aekkachai, Nutalai, Rungtiwa, Wang, Beibei, Paesen, Guido C., Lopez-Camacho, Cesar, Slon-Campos, Jose, Hallis, Bassam, Coombes, Naomi, Bewley, Kevin, Charlton, Sue, Walter, Thomas S., Skelly, Donal, Lumley, Sheila F., Dold, Christina, Levin, Robert, Dong, Tao, Pollard, Andrew J., Knight, Julian C., Crook, Derrick, Lambe, Teresa, Clutterbuck, Elizabeth, Bibi, Sagida, Flaxman, Amy, Bittaye, Mustapha, Belij-Rammerstorfer, Sandra, Gilbert, Sarah, James, William, Carroll, Miles W., Klenerman, Paul, Barnes, Eleanor, Dunachie, Susanna J., Fry, Elizabeth E., Mongkolsapaya, Juthathip, Ren, Jingshan, Stuart, David I., Screaton, Gavin R.
Published in Cell

Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera

by Supasa, Piyada, Zhou, Daming, Dejnirattisai, Wanwisa, Liu, Chang, Mentzer, Alexander J., Ginn, Helen M., Zhao, Yuguang, Duyvesteyn, Helen M.E., Nutalai, Rungtiwa, Tuekprakhon, Aekkachai, Wang, Beibei, Paesen, Guido C., Slon-Campos, Jose, López-Camacho, César, Hallis, Bassam, Coombes, Naomi, Bewley, Kevin R., Charlton, Sue, Walter, Thomas S., Barnes, Eleanor, Dunachie, Susanna J., Skelly, Donal, Lumley, Sheila F., Baker, Natalie, Shaik, Imam, Humphries, Holly E., Godwin, Kerry, Gent, Nick, Sienkiewicz, Alex, Dold, Christina, Levin, Robert, Dong, Tao, Pollard, Andrew J., Knight, Julian C., Klenerman, Paul, Crook, Derrick, Lambe, Teresa, Clutterbuck, Elizabeth, Bibi, Sagida, Flaxman, Amy, Bittaye, Mustapha, Belij-Rammerstorfer, Sandra, Gilbert, Sarah, Hall, David R., Williams, Mark A., Paterson, Neil G., James, William, Carroll, Miles W., Fry, Elizabeth E., Mongkolsapaya, Juthathip, Ren, Jingshan, Stuart, David I., Screaton, Gavin R.
Published in Cell

Performance characteristics of five immunoassays for SARS-CoV-2: a head-to-head benchmark comparison

by Ainsworth, Mark, Andersson, Monique, Auckland, Kathryn, Baillie, J Kenneth, Barnes, Eleanor, Beer, Sally, Blackwell, Luke, Borak, Martyna, Bown, Abbie, Brooks, Tim, Burgess-Brown, Nicola A, Camara, Susana, Catton, Matthew, Chau, Kevin K., Clutterbuck, Elizabeth, Coker, Jesse, Crawford-Jones, David, Crook, Derrick W, D'Arcangelo, Silvia, Dequaire, Julie M M, Dimitriadis, Stavros, Dingle, Kate E, Doherty, George, Dong, Tao, Dunachie, Susanna J, Ebner, Daniel, Emmenegger, Marc, Espinosa, Alexis, Eyre, David W, Fassih, Shayan, Felle, Sally, Fernandez-Cid, Alejandra, Fernandez Mendoza, Maria, Fordwoh, Thomas, Fox McKee, Deborah, Frater, John, Gallardo Sanchez, Veronica, Gent, Nick, Georgiou, Dominique, Groves, Christopher J, Hammond, Peter M, Hatch, Stephanie B., Hill, Jennifer, Howarth, Alison, Jones, Elizabeth, Kavanagh, James, Kirton, Richard, Klenerman, Paul, Knight, Julian C, Koukouflis, Leonidas, Kwok, Andrew, Leuschner, Ullrich, Levin, Robert, Linder, Aline, Lockett, Teresa, Marinou, Spyridoula, Martinez, Jose, Martins Ferreira, Lucas, Mason, Lara, Matthews, Philippa C, Mentzer, Alexander J, Mobbs, Alexander, Mongkolsapaya, Juthathip, Mukhopadhyay, Shubhashish M M, Neville, Matthew J, Oakley, Sarah, Oliveira, Marta, Otter, Ashley, Pascoe, Jordan, Perez, Elena, Perumal, Prem K, Peto, Timothy E A, Pickford, Hayleah, Ploeg, Rutger J, Richardson, Anastasia, Ritter, Thomas G, Roberts, David J, Rodger, Gillian, Rollier, Christine S, Rowe, Cathy, Rudkin, Justine K, Screaton, Gavin, Semple, Malcolm G, Sienkiewicz, Alex, Silva-Reyes, Laura, Skelly, Donal T, Sobrino Diaz, Alberto, Stafford, Lizzie, Stockdale, Lisa, Stoesser, Nicole, Stuart, David I, Thraves, Hannah, Vipond, Richard, Walker, Timothy M, Wareing, Susan, Warren, Yolanda, Wells, Charlie, Wilson, Clare, Withycombe, Kate, Young, Rebecca K
Published in The Lancet Infectious Diseases