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Search Results - HOFILENA, Brian J
Search Results - HOFILENA, Brian J
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A new family of H3 receptor antagonists based on the natural product Conessine
by
SANTORA, Vincent J
,
COVEL, Jonathan A
,
WEBB, Robert R
,
SAGE, Carleton
,
REN, Albert
,
PEREIRA, Guilherme
,
KNUDSEN, Jens
,
EDWARDS, Jeffrey E
,
SUAREZ, Marissa
,
FRAZER, John
,
THOMSEN, William
,
HAUSER, Erin
,
HAYASHI, Rena
,
WHELAN, Kevin
,
GROTTICK, Andrew J
,
HOFILENA, Brian J
,
IBARRA, Jason B
,
PULLEY, Michelle D
,
WEINHOUSE, Michael I
,
SENGUPTA, Dipanjan
,
DUFFIELD, Jonathan J
,
SEMPLE, Graeme
Published in
Bioorganic & medicinal chemistry letters
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Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: Discovery of (R)-1-(2-(4′-(3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl)-2-methylpyrrolidin...
by
Semple, Graeme
,
Santora, Vincent J.
,
Smith, Jeffrey M.
,
Covel, Jonathan A.
,
Hayashi, Rena
,
Gallardo, Charlemagne
,
Ibarra, Jason B.
,
Schultz, Jeffrey A.
,
Park, Douglas M.
,
Estrada, Scott A.
,
Hofilena, Brian J.
,
Smith, Brian M.
,
Ren, Albert
,
Suarez, Marissa
,
Frazer, John
,
Edwards, Jeffrey E.
,
Hart, Ryan
,
Hauser, Erin K.
,
Lorea, Jodie
,
Grottick, Andrew J.
Published in
Bioorganic & medicinal chemistry letters
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Design and evaluation of novel biphenyl sulfonamide derivatives with potent histamine H(3) receptor inverse agonist activity
by
Covel, Jonathan A
,
Santora, Vincent J
,
Smith, Jeffrey M
,
Hayashi, Rena
,
Gallardo, Charlemagne
,
Weinhouse, Michael I
,
Ibarra, Jason B
,
Schultz, Jeffrey A
,
Park, Douglas M
,
Estrada, Scott A
,
Hofilena, Brian J
,
Pulley, Michelle D
,
Smith, Brian M
,
Ren, Albert
,
Suarez, Marissa
,
Frazer, John
,
Edwards, Jeffrey
,
Hauser, Erin K
,
Lorea, Jodie
,
Semple, Graeme
,
Grottick, Andrew J
Published in
Journal of medicinal chemistry
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Design and Evaluation of Novel Biphenyl Sulfonamide Derivatives with Potent Histamine H3 Receptor Inverse Agonist Activity
by
Covel, Jonathan A.
,
Santora, Vincent J.
,
Smith, Jeffrey M.
,
Hayashi, Rena
,
Gallardo, Charlemagne
,
Weinhouse, Michael I.
,
Ibarra, Jason B.
,
Schultz, Jeffrey A.
,
Park, Douglas M.
,
Estrada, Scott A.
,
Hofilena, Brian J.
,
Pulley, Michelle D.
,
Smith, Brian M.
,
Ren, Albert
,
Suarez, Marissa
,
Frazer, John
,
Edwards, Jeffrey
,
Hauser, Erin K.
,
Lorea, Jodie
,
Semple, Graeme
,
Grottick, Andrew J.
Published in
Journal of medicinal chemistry
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Novel H3 receptor antagonists with improved pharmacokinetic profiles
by
SANTORA, Vincent J
,
COVEL, Jonathan A
,
EDWARDS, Jeffrey E
,
SUAREZ, Marissa
,
FRAZER, John
,
THOMSEN, William
,
HAUSER, Erin
,
LOREA, Jodie
,
GROTTICK, Andrew J
,
HAYASHI, Rena
,
HOFILENA, Brian J
,
IBARRA, Jason B
,
PULLEY, Michelle D
,
WEINHOUSE, Michael I
,
SEMPLE, Graeme
,
REN, Albert
,
PEREIRA, Guilherme
Published in
Bioorganic & medicinal chemistry letters
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6
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A new family of H 3 receptor antagonists based on the natural product Conessine
by
Santora, Vincent J.
,
Covel, Jonathan A.
,
Hayashi, Rena
,
Hofilena, Brian J.
,
Ibarra, Jason B.
,
Pulley, Michelle D.
,
Weinhouse, Michael I.
,
Sengupta, Dipanjan
,
Duffield, Jonathan J.
,
Semple, Graeme
,
Webb, Robert R.
,
Sage, Carleton
,
Ren, Albert
,
Pereira, Guilherme
,
Knudsen, Jens
,
Edwards, Jeffrey E.
,
Suarez, Marissa
,
Frazer, John
,
Thomsen, William
,
Hauser, Erin
,
Whelan, Kevin
,
Grottick, Andrew J.
Published in
Bioorganic & medicinal chemistry letters
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Article
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7
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Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: Discovery of (R)-1-2-(4'-(3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl-2-methylpyrrolidine...
by
SEMPLE, Graeme
,
SANTORA, Vincent J
,
HOFILENA, Brian J
,
SMITH, Brian M
,
REN, Albert
,
SUAREZ, Marissa
,
FRAZER, John
,
EDWARDS, Jeffrey E
,
HART, Ryan
,
HAUSER, Erin K
,
LOREA, Jodie
,
GROTTICK, Andrew J
,
SMITH, Jeffrey M
,
COVEL, Jonathan A
,
HAYASHI, Rena
,
GALLARDO, Charlemagne
,
IBARRA, Jason B
,
SCHULTZ, Jeffrey A
,
PARK, Douglas M
,
ESTRADA, Scott A
Published in
Bioorganic & medicinal chemistry letters
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8
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Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: Discovery of (R)-1-(2-(4&; prime; -(3-methoxypropylsulfonyl)biphenyl-4-yl)e thyl)-2-methyl...
by
Semple, Graeme
,
Santora, Vincent J
,
Smith, Jeffrey M
,
Covel, Jonathan A
,
Hayashi, Rena
,
Gallardo, Charlemagne
,
Ibarra, Jason B
,
Schultz, Jeffrey A
,
Park, Douglas M
,
Estrada, Scott A
,
Hofilena, Brian J
,
Smith, Brian M
,
Ren, Albert
,
Suarez, Marissa
,
Frazer, John
,
Edwards, Jeffrey E
,
Hart, Ryan
,
Hauser, Erin K
,
Lorea, Jodie
,
Grottick, Andrew J
Published in
Bioorganic & medicinal chemistry letters
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Article
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9
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Design and Evaluation of Novel Biphenyl Sulfonamide Derivatives with Potent Histamine H 3 Receptor Inverse Agonist Activity
by
Covel, Jonathan A.
,
Santora, Vincent J.
,
Smith, Jeffrey M.
,
Hayashi, Rena
,
Gallardo, Charlemagne
,
Weinhouse, Michael I.
,
Ibarra, Jason B.
,
Schultz, Jeffrey A.
,
Park, Douglas M.
,
Estrada, Scott A.
,
Hofilena, Brian J.
,
Pulley, Michelle D.
,
Smith, Brian M.
,
Ren, Albert
,
Suarez, Marissa
,
Frazer, John
,
Edwards, Jeffrey
,
Hauser, Erin K.
,
Lorea, Jodie
,
Semple, Graeme
,
Grottick, Andrew J.
Published in
Journal of medicinal chemistry
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10
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Novel H 3 receptor antagonists with improved pharmacokinetic profiles
by
Santora, Vincent J.
,
Covel, Jonathan A.
,
Hayashi, Rena
,
Hofilena, Brian J.
,
Ibarra, Jason B.
,
Pulley, Michelle D.
,
Weinhouse, Michael I.
,
Semple, Graeme
,
Ren, Albert
,
Pereira, Guilherme
,
Edwards, Jeffrey E.
,
Suarez, Marissa
,
Frazer, John
,
Thomsen, William
,
Hauser, Erin
,
Lorea, Jodie
,
Grottick, Andrew J.
Published in
Bioorganic & medicinal chemistry letters
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Article
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11
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Novel H sub(3) receptor antagonists with improved pharmacokinetic profiles
by
Santora, Vincent J
,
Covel, Jonathan A
,
Hayashi, Rena
,
Hofilena, Brian J
,
Ibarra, Jason B
,
Pulley, Michelle D
,
Weinhouse, Michael I
,
Semple, Graeme
,
Ren, Albert
,
Pereira, Guilherme
,
Edwards, Jeffrey E
,
Suarez, Marissa
,
Frazer, John
,
Thomsen, William
,
Hauser, Erin
,
Lorea, Jodie
,
Grottick, Andrew J
Published in
Bioorganic & medicinal chemistry
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Article
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12
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A new family of H sub(3) receptor antagonists based on the natural product Conessine
by
Santora, Vincent J
,
Covel, Jonathan A
,
Hayashi, Rena
,
Hofilena, Brian J
,
Ibarra, Jason B
,
Pulley, Michelle D
,
Weinhouse, Michael I
,
Sengupta, Dipanjan
,
Duffield, Jonathan J
,
Semple, Graeme
,
Webb, Robert R
,
Sage, Carleton
,
Ren, Albert
,
Pereira, Guilherme
,
Knudsen, Jens
,
Edwards, Jeffrey E
,
Suarez, Marissa
,
Frazer, John
,
Thomsen, William
,
Hauser, Erin
,
Whelan, Kevin
,
Grottick, Andrew J
Published in
Bioorganic & medicinal chemistry
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13
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Tau pathology reduction with SM07883, a novel, potent, and selective oral DYRK1A inhibitor: A potential therapeutic for Alzheimer's disease
by
Melchior, Benoît
,
Mittapalli, Gopi Kumar
,
Lai, Carolyn
,
Duong‐Polk, Karen
,
Stewart, Joshua
,
Güner, Bora
,
Hofilena, Brian
,
Tjitro, Amanda
,
Anderson, Scott D.
,
Herman, David S.
,
Dellamary, Luis
,
Swearingen, Christopher J.
,
Sunil, K.C.
,
Yazici, Yusuf
Published in
Aging cell
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