Defining secondary progressive multiple sclerosis

by Lorscheider, Johannes, Buzzard, Katherine, Jokubaitis, Vilija, Spelman, Tim, Havrdova, Eva, Horakova, Dana, Trojano, Maria, Izquierdo, Guillermo, Girard, Marc, Duquette, Pierre, Prat, Alexandre, Lugaresi, Alessandra, Grand'Maison, François, Grammond, Pierre, Hupperts, Raymond, Alroughani, Raed, Sola, Patrizia, Boz, Cavit, Pucci, Eugenio, Lechner-Scott, Jeanette, Bergamaschi, Roberto, Oreja-Guevara, Celia, Iuliano, Gerardo, Van Pesch, Vincent, Granella, Franco, Ramo-Tello, Cristina, Spitaleri, Daniele, Petersen, Thor, Slee, Mark, Verheul, Freek, Ampapa, Radek, Amato, Maria Pia, McCombe, Pamela, Vucic, Steve, Sánchez Menoyo, José Luis, Cristiano, Edgardo, Barnett, Michael H, Hodgkinson, Suzanne, Olascoaga, Javier, Saladino, Maria Laura, Gray, Orla, Shaw, Cameron, Moore, Fraser, Butzkueven, Helmut, Kalincik, Tomas
Published in Brain (London, England : 1878)

Treatment effectiveness of alemtuzumab compared with natalizumab, fingolimod, and interferon beta in relapsing-remitting multiple sclerosis: a cohort study

by Kalincik, Tomas, Dr, Brown, J William L, MD, Robertson, Neil, Prof, Willis, Mark, MD, Scolding, Neil, Prof, Rice, Claire M, PhD, Wilkins, Alastair, PhD, Pearson, Owen, MD, Ziemssen, Tjalf, MD, Hutchinson, Michael, Prof, McGuigan, Christopher, MD, Jokubaitis, Vilija, PhD, Spelman, Tim, PhD, Horakova, Dana, MD, Havrdova, Eva, Prof, Trojano, Maria, Prof, Izquierdo, Guillermo, MD, Lugaresi, Alessandra, MD, Prat, Alexandre, Prof, Girard, Marc, MD, Duquette, Pierre, Prof, Grammond, Pierre, MD, Alroughani, Raed, MD, Pucci, Eugenio, MD, Sola, Patrizia, MD, Hupperts, Raymond, Prof, Lechner-Scott, Jeannette, MD, Terzi, Murat, MD, Van Pesch, Vincent, Prof, Rozsa, Csilla, MD, Grand'Maison, François, Prof, Boz, Cavit, MD, Granella, Franco, MD, Slee, Mark, MD, Spitaleri, Daniele, MD, Olascoaga, Javier, MD, Bergamaschi, Roberto, MD, Verheul, Freek, MD, Vucic, Steve, MD, McCombe, Pamela, Prof, Hodgkinson, Suzanne, MD, Sanchez-Menoyo, Jose Luis, MD, Ampapa, Radek, MD, Simo, Magdolna, MD, Csepany, Tunde, MD, Ramo, Cristina, MD, Cristiano, Edgardo, MD, Barnett, Michael, MBBS, Butzkueven, Helmut, Prof, Coles, Alasdair, Prof
Published in Lancet neurology

Clinical, environmental, and genetic determinants of multiple sclerosis in children with acute demyelination: a prospective national cohort study

by Banwell, Brenda, Dr, Bar-Or, Amit, MD, Arnold, Douglas L, Prof, Sadovnick, Dessa, Prof, Narayanan, Sridar, PhD, McGowan, Melissa, MSc, O'Mahony, Julia, MSc, Magalhaes, Sandra, MSc, Hanwell, Heather, MSc, Vieth, Reinhold, Prof, Tellier, Raymond, MD, Vincent, Thierry, PhD, Disanto, Giulio, MD, Ebers, George, Prof, Wambera, Katherine, MD, Connolly, Mary B, MBBCh, Yager, Jerome, Prof, Mah, Jean K, MD, Booth, Fran, MD, Sebire, Guillaume, MD, Callen, David, MD, Meaney, Brandon, MD, Dilenge, Marie-Emmanuelle, MD, Lortie, Anne, MD, Pohl, Daniela, MD, Doja, Asif, MD, Venketaswaran, Sunita, MD, Levin, Simon, MD, MacDonald, E Athen, MD, Meek, David, MD, Wood, Ellen, MD, Lowry, Noel, MD, Buckley, David, MD, Yim, Conrad, MD, Awuku, Mark, MD, Cooper, Pamela, MD, Grand'Maison, François, MD, Baird, J Burke, MD, Bhan, Virender, MD, Marrie, Ruth Ann, MD
Published in Lancet neurology

Timing of high-efficacy therapy for multiple sclerosis: a retrospective observational cohort study

by He, Anna, Merkel, Bernd, Brown, James William L, Zhovits Ryerson, Lana, Kister, Ilya, Malpas, Charles B, Sharmin, Sifat, Horakova, Dana, Kubala Havrdova, Eva, Spelman, Tim, Izquierdo, Guillermo, Eichau, Sara, Trojano, Maria, Lugaresi, Alessandra, Hupperts, Raymond, Sola, Patrizia, Ferraro, Diana, Lycke, Jan, Grand'Maison, Francois, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Larochelle, Catherine, Svenningsson, Anders, Petersen, Thor, Grammond, Pierre, Granella, Franco, Van Pesch, Vincent, Bergamaschi, Roberto, McGuigan, Christopher, Coles, Alasdair, Hillert, Jan, Piehl, Fredrik, Butzkueven, Helmut, Kalincik, Tomas
Published in Lancet neurology

Geographical variations in sex ratio trends over time in multiple sclerosis

by Trojano, Maria
Published in PloS one

International Development of the Patient-Reported Outcome Indices for Multiple Sclerosis (PRIMUS)

by McKenna, Stephen P., PhD, Doward, Lynda C., MRes, Twiss, James, BSc, Hagell, Peter, PhD, Oprandi, Nadia C., PhD, Fisk, John, PhD, Grand'Maison, François, MD, Bhan, Virender, MD, Arbizu, Txomin, MD, Brassat, David, MD, Kohlmann, Thomas, PhD, Meads, David M., MSc, Eckert, Benjamin J., MS
Published in Value in health

Utility of the Canadian Treatment Optimization Recommendations (TOR) in MS Care

by Grand'Maison, François, Bhan, Virender, Freedman, Mark S., Myles, Mary L., Patry, David G., Selchen, Daniel H., Moriarty, Patrick, Traboulsee, Anthony L.
Published in Canadian journal of neurological sciences

International Development of the Unidimensional Fatigue Impact Scale (U-FIS)

by Doward, Lynda C., MRes, Meads, David M., MSc, Fisk, John, PhD, Twiss, James, BSc, Hagell, Peter, PhD, Oprandi, Nadia C., PhD, Grand'Maison, François, MD, Bhan, Virender, MD, Arbizu, Txomin, MD, Kohlmann, Thomas, PhD, Brassat, David, MD, Eckert, Benjamin J., MS, McKenna, Stephen P., PhD
Published in Value in health

Male Sex Is Independently Associated with Faster Disability Accumulation in Relapse-Onset MS but Not in Primary Progressive MS

by Ribbons, Karen Ann, McElduff, Patrick, Boz, Cavit, Trojano, Maria, Izquierdo, Guillermo, Duquette, Pierre, Girard, Marc, Grand'Maison, Francois, Hupperts, Raymond, Grammond, Pierre, Oreja-Guevara, Celia, Petersen, Thor, Bergamaschi, Roberto, Giuliani, Giorgio, Barnett, Michael, van Pesch, Vincent, Amato, Maria-Pia, Iuliano, Gerardo, Fiol, Marcela, Slee, Mark, Verheul, Freek, Cristiano, Edgardo, Fernandez-Bolanos, Ricardo, Saladino, Maria-Laura, Rio, Maria Edite, Cabrera-Gomez, Jose, Butzkueven, Helmut, van Munster, Erik, Den Braber-Moerland, Leontien, La Spitaleri, Daniele, Lugaresi, Alessandra, Shaygannejad, Vahid, Gray, Orla, Deri, Norma, Alroughani, Raed, Lechner-Scott, Jeannette
Published in PloS one

Country, sex, EDSS change and therapy choice independently predict treatment discontinuation in multiple sclerosis and clinically isolated syndrome

by Meyniel, Claire, Spelman, Timothy, Jokubaitis, Vilija G, Trojano, Maria, Izquierdo, Guillermo, Grand'Maison, François, Oreja-Guevara, Celia, Boz, Cavit, Lugaresi, Alessandra, Girard, Marc, Grammond, Pierre, Iuliano, Gerardo, Fiol, Marcela, Cabrera-Gomez, Jose Antonio, Fernandez-Bolanos, Ricardo, Giuliani, Giorgio, Lechner-Scott, Jeannette, Cristiano, Edgardo, Herbert, Joseph, Petkovska-Boskova, Tatjana, Bergamaschi, Roberto, van Pesch, Vincent, Moore, Fraser, Vella, Norbert, Slee, Mark, Santiago, Vetere, Barnett, Michael, Havrdova, Eva, Young, Carolyn, Sirbu, Carmen-Adella, Tanner, Mary, Rutherford, Michelle, Butzkueven, Helmut
Published in PloS one

Effect of natalizumab on disease progression in secondary progressive multiple sclerosis (ASCEND): a phase 3, randomised, double-blind, placebo-controlled trial with an open-label...

by Kapoor, Raju, Chang, Ih, Deykin, Aaron, Forrestal, Fiona, Lucas, Nisha, Yu, Bei, Arnold, Douglas L, Freedman, Mark S, Hartung, Hans-Peter, Jeffery, Douglas, Sellebjerg, Finn, Cadavid, Diego, Mikol, Dan, Bartholomé, Emmanuel, D'Hooghe, Marie, Devonshire, Virginia, Grand'Maison, François, Jacques, François, Lapierre, Yves, Morrow, Sarah, Stetkarova, Ivana, Talabova, Marika, Frederiksen, Jette, Kant, Matthias, Petersen, Thor, Eralinna, Juha-Pekka, Brassat, David, Brochet, Bruno, Vermersch, Patrick, Vukusi, Sandra, Baum, Karl, Maeurer, Mathias, Meuth, Sven, Hardiman, Orla, Achiron, Anat, Karussis, Dimitrios, Bergamaschi, Roberto, Grimaldi, Luigi, Salvetti, Marco, Scarpini, Elio, Sola, Patrizia, Zaffaroni, Mauro, Frequin, Stephan, Hupperts, Raymond, Killestein, Joep, Schrijver, Hans, van Munster, Erik, Drozdowski, Wieslaw, Fryze, Waldemar, Klodowska-Duda, Gabriela, Motta, Ewa, Podemski, Ryszard, Selmaj, Krzysztof, Stepien, Adam, Tutaj, Andrzej, Boyko, Alexey, Escartin, Antonio, Garcia-Merino, Antonio, Hernandez Perez, Miguel Angel, Ayuso, Guillermo Izquierdo, Lallana, José Meca, Gairin, Xavier Montalban, Gunnarsson, Martin, Roshanisefat, Homayoun, Sundstrom, Peter, Gran, Bruno, Kapoor, Raju, Mattison, Paul, Pearson, Owen, Rashid, Waqar, Rog, David, Silber, Eli, Bandari, Daniel, Camac, Ann, Cohan, Stanley, Fabian, Michelle, Florin, Jack, Freedman, Steven, Garwacki, Dennis, Goldman, Myla, Harrison, Daniel, Herrman, Craig, Huang, Deren, Jeffery, Douglas, Kamin, Stephen, Langer-Gould, Annette, Mattson, David, Miller, Tamara, Moses, Harold, Muley, Suraj, Nielsen, Allen, Pardo, Gabriel, Picone, MaryAnn, Robertson, Derrick, Sheppard, Christopher, Thrower, Ben, Twyman, Cary, Waubant, Emmanuelle, Yadav, Vijayshree, Zabad, Rana
Published in Lancet neurology

Persistence on therapy and propensity matched outcome comparison of two subcutaneous interferon beta 1a dosages for multiple sclerosis

by Kalincik, Tomas, Spelman, Timothy, Trojano, Maria, Duquette, Pierre, Izquierdo, Guillermo, Grammond, Pierre, Lugaresi, Alessandra, Hupperts, Raymond, Cristiano, Edgardo, Van Pesch, Vincent, Grand'maison, Francois, La Spitaleri, Daniele, Rio, Maria Edite, Flechter, Sholmo, Oreja-Guevara, Celia, Giuliani, Giorgio, Savino, Aldo, Amato, Maria Pia, Petersen, Thor, Fernandez-Bolanos, Ricardo, Bergamaschi, Roberto, Iuliano, Gerardo, Boz, Cavit, Lechner-Scott, Jeannette, Deri, Norma, Gray, Orla, Verheul, Freek, Fiol, Marcela, Barnett, Michael, van Munster, Erik, Santiago, Vetere, Moore, Fraser, Slee, Mark, Saladino, Maria Laura, Alroughani, Raed, Shaw, Cameron, Kasa, Krisztian, Petkovska-Boskova, Tatjana, den Braber-Moerland, Leontien, Chapman, Joab, Skromne, Eli, Herbert, Joseph, Poehlau, Dieter, Needham, Merrilee, Bacile, Elizabeth Alejandra Bacile, Arruda, Walter Oleschko, Paine, Mark, Singhal, Bhim, Vucic, Steve, Cabrera-Gomez, Jose Antonio, Butzkueven, Helmut
Published in PloS one

Predictors of disability worsening in clinically isolated syndrome

by Jokubaitis, Vilija G., Spelman, Tim, Kalincik, Tomas, Izquierdo, Guillermo, Grand'Maison, François, Duquette, Pierre, Girard, Marc, Lugaresi, Alessandra, Grammond, Pierre, Hupperts, Raymond, Cabrera‐Gomez, José, Oreja‐Guevara, Celia, Boz, Cavit, Giuliani, Giorgio, Fernández‐Bolaños, Ricardo, Iuliano, Gerardo, Lechner‐Scott, Jeannette, Verheul, Freek, Pesch, Vincent, Petkovska‐Boskova, Tatjana, Fiol, Marcela, Moore, Fraser, Cristiano, Edgardo, Alroughani, Raed, Bergamaschi, Roberto, Barnett, Michael, Slee, Mark, Vella, Norbert, Herbert, Joseph, Shaw, Cameron, Saladino, Maria Laura, Amato, Maria Pia, Liew, Danny, Paolicelli, Damiano, Butzkueven, Helmut, Trojano, Maria
Published in Annals of clinical and translational neurology

Treatment Optimization in Multiple Sclerosis

by Freedman, Mark S., Patry, David G., Grand'Maison, François, Myles, Mary Lou, Paty, Donald W., Selchen, Daniel H.
Published in Canadian journal of neurological sciences

Association of Initial Disease-Modifying Therapy With Later Conversion to Secondary Progressive Multiple Sclerosis

by Brown, J. William L, Coles, Alasdair, Horakova, Dana, Havrdova, Eva, Izquierdo, Guillermo, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Trojano, Maria, Lugaresi, Alessandra, Bergamaschi, Roberto, Grammond, Pierre, Alroughani, Raed, Hupperts, Raymond, McCombe, Pamela, Van Pesch, Vincent, Sola, Patrizia, Ferraro, Diana, Grand'Maison, Francois, Terzi, Murat, Lechner-Scott, Jeannette, Flechter, Schlomo, Slee, Mark, Shaygannejad, Vahid, Pucci, Eugenio, Granella, Franco, Jokubaitis, Vilija, Willis, Mark, Rice, Claire, Scolding, Neil, Wilkins, Alastair, Pearson, Owen R, Ziemssen, Tjalf, Hutchinson, Michael, Harding, Katharine, Jones, Joanne, McGuigan, Christopher, Butzkueven, Helmut, Kalincik, Tomas, Robertson, Neil
Published in JAMA : the journal of the American Medical Association

Safety and efficacy of tolebrutinib, an oral brain-penetrant BTK inhibitor, in relapsing multiple sclerosis: a phase 2b, randomised, double-blind, placebo-controlled trial

by Reich, Daniel S, Arnold, Douglas L, Vermersch, Patrick, Bar-Or, Amit, Fox, Robert J, Matta, Andre, Turner, Timothy, Wallström, Erik, Zhang, Xinyan, Mareš, Miroslav, Khabirov, Farit A, Traboulsee, Anthony, Grand'Maison, Francois, Jacques, Francois, Traboulsee, Anthony, Tyblova, Michaela, Meluzinova, Eva, Ampapa, Radek, Valis, Martin, Hradilke, Pavel, Mareš, Miroslav, Stourac, Pavel, Gross-Paju, Katrin, Laplaud, David, Mathey, Guillaume, Uitdehaag, Bernard, Evdoshenkoo, Evgeny, Popova, Ekaterina, Zakharova, Maria, Totolyan, Natalia, Litvinenko, Igor, Khabirov, Farit, Sivertseva, Stella, Hancinova, Viera, Kantorova, Ema, Gines, Maria Luisa Martinez, Montalban, Xavier, Maduano, Sara Eichau, Meca-Lallana, Jose, Ramió-Torrentà, Lluís, Nehrych, Tetyanna, Pashkovskyy, Valeriy, Moskovko, Sergii, Kalbus, Oleksandr, Khavunka, Marta, Pryshchepa, Volodymyr, Goloborodko, Alla, Wynn, Daniel, Honeycutt, William, Wray, Sibyl, Steingo, Brian, LaGanke, Christopher, Huang, Deren, Hemphill, John Michael, Goldstick, Lawrence, Robertson, Derrick
Published in Lancet neurology

Sequencing of high-efficacy disease-modifying therapies in multiple sclerosis: perspectives and approaches

by Grand'Maison, Francois, Yeung, Michael, Morrow, Sarah A, Lee, Liesly, Emond, Francois, Ward, Brian J, Laneuville, Pierre, Schecter, Robyn
Published in Neural regeneration research

The risk of secondary progressive multiple sclerosis is geographically determined but modifiable

by Sharmin, Sifat, Roos, Izanne, Simpson-Yap, Steve, Malpas, Charles, Sánchez, Marina M, Ozakbas, Serkan, Horakova, Dana, Havrdova, Eva K, Patti, Francesco, Alroughani, Raed, Izquierdo, Guillermo, Eichau, Sara, Boz, Cavit, Zakaria, Magd, Onofrj, Marco, Lugaresi, Alessandra, Weinstock-Guttman, Bianca, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Terzi, Murat, Amato, Maria Pia, Karabudak, Rana, Grand’Maison, Francois, Khoury, Samia J, Grammond, Pierre, Lechner-Scott, Jeannette, Buzzard, Katherine, Skibina, Olga, van der Walt, Anneke, Butzkueven, Helmut, Turkoglu, Recai, Altintas, Ayse, Maimone, Davide, Kermode, Allan, Shalaby, Nevin, Pesch, Vincent V, Butler, Ernest, Sidhom, Youssef, Gouider, Riadh, Mrabet, Saloua, Gerlach, Oliver, Soysal, Aysun, Barnett, Michael, Kuhle, Jens, Hughes, Stella, Sa, Maria J, Hodgkinson, Suzanne, Oreja-Guevara, Celia, Ampapa, Radek, Petersen, Thor, Ramo-Tello, Cristina, Spitaleri, Daniele, McCombe, Pamela, Taylor, Bruce, Prevost, Julie, Foschi, Matteo, Slee, Mark, McGuigan, Chris, Laureys, Guy, Hijfte, Liesbeth V, de Gans, Koen, Solaro, Claudio, Oh, Jiwon, Macdonell, Richard, Aguera-Morales, Eduardo, Singhal, Bhim, Gray, Orla, Garber, Justin, Wijmeersch, Bart V, Simu, Mihaela, Castillo-Triviño, Tamara, Sanchez-Menoyo, Jose L, Khurana, Dheeraj, Al-Asmi, Abdullah, Al-Harbi, Talal, Deri, Norma, Fragoso, Yara, Lalive, Patrice H, Sinnige, L G F, Shaw, Cameron, Shuey, Neil, Csepany, Tunde, Sempere, Angel P, Moore, Fraser, Decoo, Danny, Willekens, Barbara, Gobbi, Claudio, Massey, Jennifer, Hardy, Todd, Parratt, John, Kalincik, Tomas
Published in Brain (London, England : 1878)

Comparison of switching to 6-week dosing of natalizumab versus continuing with 4-week dosing in patients with relapsing-remitting multiple sclerosis (NOVA): a randomised, controlle...

by Foley, John F, Defer, Gilles, Ryerson, Lana Zhovtis, Cohen, Jeffrey A, Arnold, Douglas L, Butzkueven, Helmut, Cutter, Gary, Giovannoni, Gavin, Killestein, Joep, Wiendl, Heinz, Smirnakis, Karen, Xiao, Shan, Kong, George, Kuhelj, Robert, Campbell, Nolan, van der Walt, Anneke, Dwyer, Christopher, Buzzard, Katherine, Spies, Judith, Parratt, John, van Pesch, Vincent, Willekens, Barbara, Perrotta, Gaetano, Bartholomé, Emmanuel, Grand'Maison, Francois, Jacques, Francois, Giacomini, Paul, Vosoughi, Reza, Girard, Jean-Marc, de Seze, Jerome, Lebrun Frenay, Christine, Ruet, Aurelie, Laplaud, David-Axel, Reifschneider, Gerd, Wagner, Bert, Rauer, Sebastian, Pul, Refik, Seipelt, Maria, Berthele, Achim, Klotz, Luisa, Kallmann, Boris-Alexander, Paul, Friedemann, Achiron, Anat, Lus, Giacomo, Centonze, Diego, Patti, Francesco, Grimaldi, Luigi, Hupperts, Raymond, Frequin, Stephan, Fermont, Jiske, Madueno, Sara Eichau, Alonso Torres, Ana Maria, Costa-Frossard França, Lucienne, Meca-Lallana, Jose Eustasio, Ruiz, Luis Brieva, Pearson, Owen, Rog, David, Evangelou, Nikolaos, Ismail, Azza, Lathi, Ellen, Fox, Edward, Leist, Thomas, Sloane, Jacob, Wu, Gregory, Khatri, Bhupendra, Steingo, Brian, Thrower, Ben, Gudesblatt, Mark, Calkwood, Jonathan, Bandari, Daniel, Scagnelli, John, Laganke, Christopher, Robertson, Derrick, Kipp, Lucas, Belkin, Martin, Cohan, Stanley, Goldstick, Lawrence, Courtney, Ardith, Vargas, Wendy, Sylvester, Andrew, Srinivasan, Jayshri, Kannan, Meena, Picone, Maryann, English, Jeffrey, Napoli, Salvatore, Balabanov, Roumen, Zaydan, Islam, Nicholas, Jacqueline, Kaplan, Jeffrey, Lublin, Fred, Riser, Emily, Miller, Tamara, Alvarez, Enrique, Wray, Sibyl, Gross, Jeffrey, Pawate, Siddharama, Hersh, Carrie, McCarthy, Lucas, Crayton, Heidi, Graves, Jennifer
Published in Lancet neurology

Early clinical markers of aggressive multiple sclerosis

by Malpas, Charles B, Manouchehrinia, Ali, Sharmin, Sifat, Roos, Izanne, Horakova, Dana, Havrdova, Eva Kubala, Trojano, Maria, Izquierdo, Guillermo, Eichau, Sara, Bergamaschi, Roberto, Sola, Patrizia, Ferraro, Diana, Lugaresi, Alessandra, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Grammond, Pierre, Grand'Maison, Francois, Ozakbas, Serkan, Van Pesch, Vincent, Granella, Franco, Hupperts, Raymond, Pucci, Eugenio, Boz, Cavit, Sidhom, Youssef, Gouider, Riadh, Spitaleri, Daniele, Soysal, Aysun, Petersen, Thor, Verheul, Freek, Karabudak, Rana, Turkoglu, Recai, Ramo-Tello, Cristina, Terzi, Murat, Cristiano, Edgardo, Slee, Mark, McCombe, Pamela, Macdonell, Richard, Fragoso, Yara, Olascoaga, Javier, Altintas, Ayse, Olsson, Tomas, Butzkueven, Helmut, Hillert, Jan, Kalincik, Tomas
Published in Brain (London, England : 1878)