Sphingosine 1-phosphate-induced nitric oxide production simultaneously controls endothelial barrier function and vascular tone in resistance arteries

by Kerage, Daniel, Gombos, Randi B., Wang, Shaomeng, Brown, Meagan, Hemmings, Denise G.
Published in Vascular pharmacology

Inhibitory Effect of Individual or Combinations of Broadly Neutralizing Antibodies and Antiviral Reagents against Cell-Free and Cell-to-Cell HIV-1 Transmission

by Gombos, Randi B, Kolodkin-Gal, Dror, Eslamizar, Leila, Owuor, Joshua O, Mazzola, Emanuele, Gonzalez, Ana M, Korioth-Schmitz, Birgit, Gelman, Rebecca S, Montefiori, David C, Haynes, Barton F, Schmitz, Joern E
Published in Journal of virology

Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody

by Gombos, Randi B, Gonzalez, Ana, Manrique, Mariana, Chand, Dhan, Savitsky, David, Morin, Benjamin, Breous-Nystrom, Ekaterina, Dupont, Christopher, Ward, Rebecca A, Mundt, Cornelia, Duckless, Benjamin, Tang, Hao, Findeis, Mark A, Schuster, Andrea, Waight, Jeremy D, Underwood, Dennis, Clarke, Christopher, Ritter, Gerd, Merghoub, Taha, Schaer, David, Wolchok, Jedd D, van Dijk, Marc, Buell, Jennifer S, Cuillerot, Jean-Marie, Stein, Robert, Drouin, Elise E, Wilson, Nicholas S
Published in PloS one

Efficiency of Cell-Free and Cell-Associated Virus in Mucosal Transmission of Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus

by Kolodkin-Gal, Dror, Hulot, Sandrine L, Korioth-Schmitz, Birgit, Gombos, Randi B, Zheng, Yi, Owuor, Joshua, Lifton, Michelle A, Ayeni, Christian, Najarian, Robert M, Yeh, Wendy W, Asmal, Mohammed, Zamir, Gideon, Letvin, Norman L
Published in Journal of Virology

Impact of Local Endothelial Challenge with Cytomegalovirus or Glycoprotein B on Vasodilation in Intact Pressurized Arteries from Nonpregnant and Pregnant Mice

by GOMBOS, Randi B, TEEFY, Jana, LEE, Albert, HEMMINGS, Denise G
Published in Biology of reproduction

Impact of Local Endothelial Challenge with Cytomegalovirus or Glycoprotein B on Vasodilation in Intact Pressurized Arteries from Nonpregnant and Pregnant Mice1

by Gombos, Randi B, Teefy, Jana, Lee, Albert, Hemmings, Denise G
Published in Biology of reproduction

Differential effects on nitric oxide-mediated vasodilation in mesenteric and uterine arteries from cytomegalovirus-infected mice

by Gombos, Randi B, Hemmings, Denise G
Published in American journal of physiology. Heart and circulatory physiology

Defining the DNA mismatch repair-dependent apoptotic pathway in primary cells: Evidence for p53-independence and involvement of centrosomal caspase 2

by Narine, Kelly A.D., Keuling, Angela M., Gombos, Randi, Tron, Victor A., Andrew, Susan E., Young, Leah C.
Published in DNA repair

Selective FcγR Co-engagement on APCs Modulates the Activity of Therapeutic Antibodies Targeting T Cell Antigens

by Waight, Jeremy D., Chand, Dhan, Dietrich, Sylvia, Gombos, Randi, Horn, Thomas, Gonzalez, Ana M., Manrique, Mariana, Swiech, Lukasz, Morin, Benjamin, Brittsan, Christine, Tanne, Antoine, Akpeng, Belinda, Croker, Ben A., Buell, Jennifer S., Stein, Robert, Savitsky, David A., Wilson, Nicholas S.
Published in Cancer cell

Abstract 2390: FcgR co-engagement by anti-TIGIT monoclonal antibodies enhances T cell functionality and antitumor immune responses

by Chand, Dhan, Waight, Jeremy D., Paltrinieri, Elena, Dietrich, Sylvia, Bushell, Mark, Costa, Mathew, Gombos, Randi, Wilson, Nicholas S., Buell, Jennifer S., Stein, Robert B., Duncan, Alexander, Savitsky, David A.
Published in Cancer research (Chicago, Ill.)

Abstract 2721: Selective FcγR engagement by CTLA-4 antibodies results in increased functional activity

by Waight, Jeremy D., Chand, Dhan, Dietrich, Sylvia, Gombos, Randi, Horn, Thomas, Gonzalez, Ana M., Manrique, Mariana, Tanne, Antoine, Dupont, Christopher, Swiech, Lukasz, Croker, Ben A., Buell, Jennifer S., Stein, Robert, Duncan, Alex, Savitsky, David A., Wilson, Nicholas S.
Published in Cancer research (Chicago, Ill.)

Differential effects on nitric oxide-mediated vasodilation in mesenteric and uterine arteries from cytomegalovirus-infected mice

by GOMBOS, Randi B, HEMMINGS, Denise G
Published in American journal of physiology. Heart and circulatory physiology

Abstract 3654: AGEN1884, an IgG1 anti-CTLA-4 antibody, combines effectively with PD-1 blockade in primary human T cell assays and in a non-human primate pharmacodynamic (PD) model

by Drouin, Elise E., Savitsky, David, Gonzalez, Ana M., Gombos, Randi, Chand, Dhan, Waight, Jeremy, Yang, Xia, Khattar, Mithun, Morin, Benjamin, Findeis, Mark, Schaer, David, Merghoub, Taha, Ritter, Gerd, Tanne, Antoine, Dijk, Marc van, Goldberg, John M., Levey, Daniel, Castle, John, Cuillerot, Jean-Marie, Buell, Jennifer S., Stein, Robert, Wilson, Nicholas S.
Published in Cancer research (Chicago, Ill.)

Human cytomegalovirus (HCMV) infection requires S1P to increase endothelial permeability

by Kerage, Daniel, Wang, Maggie, Amin, Shreya, Gombos, Randi, Hemmings, Denise G
Published in Placenta (Eastbourne)

Abstract 3204: INCAGN01949: an anti-OX40 agonist antibody with the potential to enhance tumor-specific T-cell responsiveness, while selectively depleting intratumoral regulatory T...

by Gonzalez, Ana Maria, Manrique, Mariana L., Breous, Ekaterina, Savitsky, David, Waight, Jeremy, Gombos, Randi, Liu, Yuqi, Lin, Shiwen, Merghoub, Taha, Hirschhorn-Cymerman, Daniel, Ritter, Gerd, Wolchok, Jedd, Scherle, Peggy, Hollis, Gregory, Huber, Reid, Van Dijk, Marc, Stein, Robert, Wilson, Nicholas S.
Published in Cancer research (Chicago, Ill.)

Abstract 5005: AGEN1884 and AGEN2041: Two functionally distinct anti-CTLA-4 antagonist antibodies

by Drouin, Elise E., Gonzalez, Ana, Tang, Hao, Savitsky, David, Gombos, Randi, Waight, Jeremy, Duckless, Benjamin, Schuster, Andrea, Wang, Lili, Lin, Shiwen, Mundt, Cornelia, Ritter, Gerd, Merghoub, Taha, Draleau, Kyle, Wolchok, Jedd, Levey, Daniel, Buell, Jennifer, van Dijk, Marc, Goldberg, John M., Stein, Robert, Wilson, Nicholas S.
Published in Cancer research (Chicago, Ill.)

Abstract 3220: A novel agonist antibody (INCAGN01876) that targets the costimulatory receptor GITR

by Gonzalez, Ana Maria, Breous, Ekaterina, Manrique, Mariana L., Savitsky, David, Waight, Jeremy, Gombos, Randi, Liu, Yuqi, Lin, Shiwen, Leger, Olivier, Seibert, Volker, Tsuji, Takemasa, Merghoub, Taha, Budha, Sadna, Zappasodi, Roberta, Ritter, Gerd, Wolchok, Jedd, Scherle, Peggy, Hollis, Gregory, Huber, Reid, Van Dijk, Marc, Stein, Robert, Wilson, Nicholas
Published in Cancer research (Chicago, Ill.)

Ipilimumab and nivolumab combined with anthracycline-based chemotherapy in metastatic hormone receptor-positive breast cancer: a randomized phase 2b trial

by Andresen, Nikolai Kragøe, Røssevold, Andreas Hagen, Quaghebeur, Claire, Gilje, Bjørnar, Boge, Beate, Gombos, Andrea, Falk, Ragnhild Sørum, Mathiesen, Randi R., Julsrud, Lars, Garred, Øystein, Russnes, Hege G., Lereim, Ragnhild Reehorst, Chauhan, Sudhir Kumar, Lingjærde, Ole Christian, Dunn, Claire, Naume, Bjørn, Kyte, Jon Amund
Published in Journal for immunotherapy of cancer

Risk for non-home discharge following surgery for ischemic mitral valve disease

by Lala, Anuradha, Chang, Helena L., Liu, Xiaoyu, Thourani, Vinod H., Mack, Michael J., Moskowitz, Alan J., Gelijns, Annetine C., Stevenson, Lynne W., DeRose, Joseph J., Wang, Alice, Acker, Michael A., Ailawadi, Gorav, Gordon, David, Jeffries, Neal O., Gombos, Ilana Kogan, Ralph, Jennifer, Weisel, Richard D., Gardner, Timothy J., Rose, Eric A., Ascheim, Deborah D., Moquete, Ellen, Chang, Helena, Foo, James, Kirkwood, Katherine, Williams, Deborah, Weglinski, Michael, Wood, Carrie, Smith, Robert L., Chen, Frederick Y., Nohria, Anju, Shekar, Prem, Davidson, Michael, Bolman, R. Morton, Stevens, Louis-Mathieu, Dionne, Joannie, Lackner, Pamela, Berroteran, Leoma, Sweeney, Denise Kosty, Pattakos, Gregory, Goldsmith, Lyn, Smith, Craig R., Schwartz, Allan, Alexander, John H., Milano, Carmelo A., Glower, Donald D., Mathew, Joseph P., Harrison, J. Kevin, Welsh, Stacey, Williams, Judson B., Kypson, Alan P., Harris, Malissa, O'Neal, Allison, Puskas, John D., Guyton, Robert, Baio, Kim, Voisine, Pierre, Dagenais, François, Ad, Niv, Slaughter, Mark, Hampton, Lynne C., D'Alessandro, David A., DeRose, Joseph J., Goldstein, Daniel J., Spevak, Daniel, Pellerin, Michel, Denault, André, Siegenthaler, Michael P., Iraola, Margaret, Kinn, Bradley, Pagé, Pierre, Latter, David, Errett, Lee, Verma, Subodh, Christakis, George, Yau, Terry, Farkouh, Michael, Fredericks, Suzanne, Mociornita, Amelia, Choy, Jonathan, Meyer, Steven, Young, Cindi A., Beach, Dana, Mayer, Mary Lou, Starnes, Vaughn A., Shavalle, David, Gahring, Kim, Holubkov, Richard, Miller, Frank, Murkin, John M., Sellke, Frank, Williams, David O., Richenbacher, Wayne, Rao, Vivek, Miller, Rachel, Pinney, Sean, Roberts, William C., Walsh, Mary N., Zeng, Xin, Hung, David, Brawner, Clinton A.
Published in The Journal of thoracic and cardiovascular surgery

Cost-effectiveness of coronary artery bypass grafting plus mitral valve repair versus coronary artery bypass grafting alone for moderate ischemic mitral regurgitation

by Michler, Robert E., Ailawadi, Gorav, Perrault, Louis P., Miller, Marissa A., O'Sullivan, Karen, Hung, Judy W., Overbey, Jessica R., Iraola, Margaret, Gelijns, Annetine C., Moskowitz, Alan J., Miller, Marissa A., Taddei-Peters, Wendy C., Geller, Nancy L., Lee, Albert, Gelijns, Annetine C., Ascheim, Deborah D., Moskowitz, Alan J., Bagiella, Emilia, Moquete, Ellen, Chang, Helena, Chen, Yingchun, Goldfarb, Seth, Gupta, Lopa, O'Sullivan, Karen, Santos, Milerva, Weglinski, Michael, Williams, Paula, Wiggers, Henrik, Adame, Tracine, Ryan, William, Grayburn, Paul, Chen, Frederick Y., Aranki, Sary, Davidson, Michael, Prieto, Ignacio, Dionne, Joannie, Lackner, Pamela, Berroteran, Leoma, Smith, Craig R., Naka, Yoshifumi, Stewart, Allan, Van Patten, Danielle, Alexander, John H., Mathew, Joseph P., Parsa, Cyrus J., Tong, Betty C., Ferguson, T. Bruce, Akers, Brenda, Puskas, John D., Baio, Kim, Speir, Alan M., Magee, Patrick, Keyte, Sally, Dang, Minh, Slaughter, Mark, Headlee, Marsha, Moody, Heather, Birks, Emma, Shepard, Stephanie A., Nanney, Tracy, Hampton, Lynne C., DeRose, Joseph J., Taub, Cynthia, Perrault, Louis P., Basmadjian, Arsène-Joseph, Bouchard, Denis, Carrier, Michel, Tanguay, Jean François, El-Hamamsy, Ismail, Robichaud, Sophie, Corcoran, Philip C., Hasan, Ayseha, McDavid, Asia, Peterson, Mark D., Cohen, Gideon, Moussa, Fuad, Christakis, George, David, Tirone, Garrard, Lisa, Meyer, Steven, Kuurstra, Emily, Dent, John M., Kern, John, Dixon, Dennis O., Haigney, Mark, Holubkov, Richard, Jacobs, Alice, Murkin, John M., Spertus, John, McDonald, Cheryl L., Williams, David O., Richenbacher, Wayne, Rao, Vivek, Miller, Rachel, Pinney, Sean, Roberts, William C., Walsh, Mary N., Keteyian, Stephen J., Aldred, Heather, Browndyke, Jeffrey
Published in The Journal of thoracic and cardiovascular surgery