Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study

by Carlson, Christopher S, Matise, Tara C, North, Kari E, Haiman, Christopher A, Fesinmeyer, Megan D, Buyske, Steven, Schumacher, Fredrick R, Peters, Ulrike, Franceschini, Nora, Ritchie, Marylyn D, Duggan, David J, Spencer, Kylee L, Dumitrescu, Logan, Eaton, Charles B, Thomas, Fridtjof, Young, Alicia, Carty, Cara, Heiss, Gerardo, Le Marchand, Loic, Crawford, Dana C, Hindorff, Lucia A, Kooperberg, Charles L
Published in PLoS biology

Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach

by Mendelson, Michael M, Marioni, Riccardo E, Joehanes, Roby, Liu, Chunyu, Hedman, Åsa K, Aslibekyan, Stella, Demerath, Ellen W, Guan, Weihua, Zhi, Degui, Yao, Chen, Huan, Tianxiao, Willinger, Christine, Chen, Brian, Courchesne, Paul, Multhaup, Michael, Irvin, Marguerite R, Cohain, Ariella, Schadt, Eric E, Grove, Megan L, Bressler, Jan, North, Kari, Sundström, Johan, Gustafsson, Stefan, Shah, Sonia, McRae, Allan F, Harris, Sarah E, Gibson, Jude, Redmond, Paul, Corley, Janie, Murphy, Lee, Starr, John M, Kleinbrink, Erica, Lipovich, Leonard, Visscher, Peter M, Wray, Naomi R, Krauss, Ronald M, Fallin, Daniele, Feinberg, Andrew, Absher, Devin M, Fornage, Myriam, Pankow, James S, Lind, Lars, Fox, Caroline, Ingelsson, Erik, Arnett, Donna K, Boerwinkle, Eric, Liang, Liming, Levy, Daniel, Deary, Ian J
Published in PLoS medicine

A multi-population phenome-wide association study of genetically-predicted height in the Million Veteran Program

by Raghavan, Sridharan, Huang, Jie, Tcheandjieu, Catherine, Huffman, Jennifer E, Litkowski, Elizabeth, Liu, Chang, Ho, Yuk-Lam A, Hunter-Zinck, Haley, Zhao, Hongyu, Marouli, Eirini, North, Kari E, Lange, Ethan, Lange, Leslie A, Voight, Benjamin F, Gaziano, J Michael, Pyarajan, Saiju, Hauser, Elizabeth R, Tsao, Philip S, Wilson, Peter W F, Chang, Kyong-Mi, Cho, Kelly, O'Donnell, Christopher J, Sun, Yan V, Assimes, Themistocles L
Published in PLoS genetics

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

by Horikoshi, Momoko, Mӓgi, Reedik, van de Bunt, Martijn, Surakka, Ida, Sarin, Antti-Pekka, Mahajan, Anubha, Marullo, Letizia, Thorleifsson, Gudmar, Hӓgg, Sara, Hottenga, Jouke-Jan, Ladenvall, Claes, Ried, Janina S, Winkler, Thomas W, Willems, Sara M, Pervjakova, Natalia, Esko, Tõnu, Beekman, Marian, Nelson, Christopher P, Willenborg, Christina, Wiltshire, Steven, Ferreira, Teresa, Fernandez, Juan, Gaulton, Kyle J, Steinthorsdottir, Valgerdur, Hamsten, Anders, Magnusson, Patrik K E, Willemsen, Gonneke, Milaneschi, Yuri, Robertson, Neil R, Groves, Christopher J, Bennett, Amanda J, Lehtimӓki, Terho, Viikari, Jorma S, Rung, Johan, Lyssenko, Valeriya, Perola, Markus, Heid, Iris M, Herder, Christian, Grallert, Harald, Müller-Nurasyid, Martina, Roden, Michael, Hypponen, Elina, Isaacs, Aaron, van Leeuwen, Elisabeth M, Karssen, Lennart C, Mihailov, Evelin, Houwing-Duistermaat, Jeanine J, de Craen, Anton J M, Deelen, Joris, Havulinna, Aki S, Blades, Matthew, Hengstenberg, Christian, Erdmann, Jeanette, Schunkert, Heribert, Kaprio, Jaakko, Tobin, Martin D, Samani, Nilesh J, Lind, Lars, Salomaa, Veikko, Lindgren, Cecilia M, Slagboom, P Eline, Metspalu, Andres, van Duijn, Cornelia M, Eriksson, Johan G, Peters, Annette, Gieger, Christian, Jula, Antti, Groop, Leif, Raitakari, Olli T, Power, Chris, Penninx, Brenda W J H, de Geus, Eco, Smit, Johannes H, Boomsma, Dorret I, Pedersen, Nancy L, Ingelsson, Erik, Thorsteinsdottir, Unnur, Stefansson, Kari, Ripatti, Samuli, Prokopenko, Inga, McCarthy, Mark I, Morris, Andrew P
Published in PLoS genetics

Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes

by Naukkarinen, Jussi, Surakka, Ida, Pietiläinen, Kirsi H, Rissanen, Aila, Salomaa, Veikko, Ripatti, Samuli, Yki-Järvinen, Hannele, van Duijn, Cornelia M, Wichmann, H-Erich, Kaprio, Jaakko, Taskinen, Marja-Riitta, Peltonen, Leena
Published in PLoS genetics

Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases

by Perry, John R B, Voight, Benjamin F, Yengo, Loïc, Amin, Najaf, Dupuis, Josée, Ganser, Martha, Grallert, Harald, Navarro, Pau, Li, Man, Qi, Lu, Steinthorsdottir, Valgerdur, Scott, Robert A, Almgren, Peter, Arking, Dan E, Aulchenko, Yurii, Balkau, Beverley, Benediktsson, Rafn, Bergman, Richard N, Boerwinkle, Eric, Bonnycastle, Lori, Burtt, Noël P, Campbell, Harry, Charpentier, Guillaume, Collins, Francis S, Gieger, Christian, Green, Todd, Hadjadj, Samy, Hattersley, Andrew T, Herder, Christian, Hofman, Albert, Johnson, Andrew D, Kottgen, Anna, Kraft, Peter, Labrune, Yann, Langenberg, Claudia, Manning, Alisa K, Mohlke, Karen L, Morris, Andrew P, Oostra, Ben, Pankow, James, Petersen, Ann-Kristin, Pramstaller, Peter P, Prokopenko, Inga, Rathmann, Wolfgang, Rayner, William, Roden, Michael, Rudan, Igor, Rybin, Denis, Scott, Laura J, Sigurdsson, Gunnar, Sladek, Rob, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Tuomilehto, Jaakko, Uitterlinden, Andre G, Vivequin, Sidonie, Weedon, Michael N, Wright, Alan F, Hu, Frank B, Illig, Thomas, Kao, Linda, Meigs, James B, Wilson, James F, Stefansson, Kari, van Duijn, Cornelia, Altschuler, David, Morris, Andrew D, Boehnke, Michael, McCarthy, Mark I, Froguel, Philippe, Palmer, Colin N A, Wareham, Nicholas J, Groop, Leif, Frayling, Timothy M, Cauchi, Stéphane
Published in PLoS genetics