Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, control...

by Eng, Cathy, Kim, Tae Won, Bendell, Johanna, Argilés, Guillem, Tebbutt, Niall C, Di Bartolomeo, Maria, Falcone, Alfredo, Fakih, Marwan, Kozloff, Mark, Segal, Neil H, Sobrero, Alberto, Yan, Yibing, Chang, Ilsung, Uyei, Anne, Roberts, Louise, Ciardiello, Fortunato, Ahn, JB, Asselah, J, Badarinath, S, Baijal, S, Begbie, S, Berry, S, Canon, JL, Carbone, RG, Cervantes, A, Cha, YJ, Chang, K, Chaudhry, A, Chmielowska, E, Cho, SH, Chu, D, Couture, F, Cultrera, J, Cunningham, D, Van Cutsem, E, Cuyle, PJ, Davies, J, Dowden, S, Dvorkin, M, Ganju, V, Garcia, RV, Kerr, R, Kim, TY, King, K, Kortmansky, J, Kozloff, M, Lam, KO, Lee, J, Lee, AS, Lesperance, B, Luppi, G, Ma, B, Maiello, E, Mandanas, R, Marshall, J, Marx, G, Mullamitha, S, Nechaeva, M, Park, JO, Pavlakis, N, Ponce, CG, Potemski, P, Raouf, S, Reeves, J, Segal, N, Siena, S, Smolin, A, Streb, JO, Strickland, A, Szutowicz-Zielinska, E, Tabernero, JM, Tan, B, Valera, JS, Van den Eynde, M, Vergauwe, P, Vickers, M, Womack, M, Wroblewska, M, Young, R
Published in The lancet oncology

Bevacizumab is equally effective and no more toxic in elderly patients with advanced colorectal cancer: a subgroup analysis from the AGITG MAX trial: an international randomised co...

by Price, T.J., Zannino, D., Wilson, K., Simes, R.J., Cassidy, J., Van Hazel, G.A., Robinson, B.A., Broad, A., Ganju, V., Ackland, S.P., Tebbutt, N.C.
Published in Annals of oncology

Randomised, non-comparative phase II study of weekly docetaxel with cisplatin and 5-fluorouracil or with capecitabine in oesophagogastric cancer: the AGITG ATTAX trial

by TEBBUTT, N. C, CUMMINS, M. M, SOURJINA, T, STRICKLAND, A, VAN HAZEL, G, GANJU, V, GIBBS, D, STOCKLER, M, GEBSKI, V, ZALCBERG, J
Published in British journal of cancer

Docetaxel plus cetuximab as second-line treatment for docetaxel-refractory oesophagogastric cancer: the AGITG ATTAX2 trial

by TEBBUTT, N. C, PARRY, M. M, ZANNINO, D, STRICKLAND, A. H, VAN HAZEL, G. A, PAVLAKIS, N, GANJU, V, MELLOR, D, DOBROVIC, A, GEBSKI, V. J
Published in British journal of cancer

232 Final Results of a Phase II Study of the Combination of Oral Vinorelbine (NVBo), Capecitabine (X) and Trastuzumab (H) in HER2-positive Metastatic Breast Cancer (MBC)

by Petruzelka, L, Ganju, V, Conte, P.F, Tubiana-Mathieu, N, Majois, F, Espie, M, Llombart, A, Gil, M. Gil, Villanova, G, Chan, A
Published in European journal of cancer (1990)

Whole-genome characterization of chemoresistant ovarian cancer

by Patch, Ann-Marie, Christie, Elizabeth L, Etemadmoghadam, Dariush, Garsed, Dale W, George, Joshy, Fereday, Sian, Nones, Katia, Cowin, Prue, Alsop, Kathryn, Bailey, Peter J, Kassahn, Karin S, Newell, Felicity, Quinn, Michael C J, Kazakoff, Stephen, Quek, Kelly, Wilhelm-Benartzi, Charlotte, Curry, Ed, Leong, Huei San, Hamilton, Anne, Mileshkin, Linda, Au-Yeung, George, Kennedy, Catherine, Hung, Jillian, Chiew, Yoke-Eng, Harnett, Paul, Friedlander, Michael, Quinn, Michael, Pyman, Jan, Cordner, Stephen, O'Brien, Patricia, Leditschke, Jodie, Young, Greg, Strachan, Kate, Waring, Paul, Azar, Walid, Mitchell, Chris, Traficante, Nadia, Hendley, Joy, Thorne, Heather, Shackleton, Mark, Miller, David K, Arnau, Gisela Mir, Tothill, Richard W, Holloway, Timothy P, Semple, Timothy, Harliwong, Ivon, Nourse, Craig, Nourbakhsh, Ehsan, Manning, Suzanne, Idrisoglu, Senel, Bruxner, Timothy J C, Christ, Angelika N, Poudel, Barsha, Holmes, Oliver, Anderson, Matthew, Leonard, Conrad, Lonie, Andrew, Hall, Nathan, Wood, Scott, Taylor, Darrin F, Xu, Qinying, Fink, J Lynn, Waddell, Nick, Drapkin, Ronny, Stronach, Euan, Gabra, Hani, Brown, Robert, Jewell, Andrea, Nagaraj, Shivashankar H, Markham, Emma, Wilson, Peter J, Ellul, Jason, McNally, Orla, Doyle, Maria A, Vedururu, Ravikiran, Stewart, Collin, Lengyel, Ernst, Pearson, John V, Waddell, Nicola, deFazio, Anna, Grimmond, Sean M, Bowtell, David D L
Published in Nature (London)

Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): final overall surviv...

by Ryan, Charles J, Prof, Smith, Matthew R, Prof, Fizazi, Karim, Prof, Saad, Fred, Prof, Mulders, Peter F A, Prof, Sternberg, Cora N, MD, Miller, Kurt, Prof, Logothetis, Christopher J, Prof, Shore, Neal D, MD, Small, Eric J, Prof, Carles, Joan, MD, Flaig, Thomas W, MD, Taplin, Mary-Ellen, MD, Higano, Celestia S, Prof, de Souza, Paul, Prof, de Bono, Johann S, Prof, Griffin, Thomas W, MD, De Porre, Peter, MD, Yu, Margaret K, MD, Park, Youn C, PhD, Li, Jinhui, PhD, Kheoh, Thian, PhD, Naini, Vahid, PharmD, Molina, Arturo, MD, Rathkopf, Dana E, MD
Published in The lancet oncology

Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma

by Kondrashova, Olga, Topp, Monique, Nesic, Ksenija, Lieschke, Elizabeth, Ho, Gwo-Yaw, Harrell, Maria I, Zapparoli, Giada V, Hadley, Alison, Holian, Robert, Boehm, Emma, Heong, Valerie, Sanij, Elaine, Pearson, Richard B, Krais, John J, Johnson, Neil, McNally, Orla, Ananda, Sumitra, Alsop, Kathryn, Hutt, Karla J, Kaufmann, Scott H, Lin, Kevin K, Harding, Thomas C, Traficante, Nadia, deFazio, Anna, McNeish, Iain A, Bowtell, David D, Swisher, Elizabeth M, Dobrovic, Alexander, Wakefield, Matthew J, Scott, Clare L
Published in Nature communications

EP08.02-109 A Drug-Drug Interaction Study of Mobocertinib and Midazolam in Patients With Advanced Non-Small Cell Lung Cancer

by Hanley, M.J., Zhang, S., Pavlakis, N., Soo, R., van der Wekken, A.J., Ganju, V., Pina, A., Dong, Q., Gupta, N.
Published in Journal of thoracic oncology

Prognostic gene expression signature for high-grade serous ovarian cancer

by Intermaggio, M.P., Leong, H.S., Chen, S., Elatre, W., Gilks, B., Volchek, M., Wang, C., Mackenzie, R., George, J., Bowtell, D., Chenevix-Trench, G., Green, A., Gertig, D., Fereday, S., Moore, S., Hung, J., Harrap, K., Malt, M., Robertson, R., Maidens, J., Jayde, V., Mamers, P., Schmidt, T., Ball, C., Bilic, Sanela, Stuart-Harris, R., Clingan, P., Glasgow, A., Shannon, J., Young, B., Robertson, G., Carter, J., Dalrymple, C., Russell, P., Links, M., Jaworski, R., Crandon, A., Horwood, K., Obermair, A., Wyld, D., Davy, M., Dodd, T., Healy, T., Pittman, K., Henderson, D., Pierdes, J., Brown, B., Hyde, S., Healy, D., McNealage, J., Simpson, I., Fox, S., Lade, S., Loughrey, M., Neesham, D., Bell, R., Ng, L.F., Whiteman, D., Fereday, S., Steed, H., Koziak, J.M., Goranova, T., Silva De Silva, D., Ramón y Cajal, T., García-Donas, J., Rodriguez, G.C., Harris, H.R., Greene, C.S., Zelaya, R.A., Sinn, P., Menkiszak, J., Pearce, C.L., Rhenius, V., Piskorz, A.M., Sharma, R., Johnatty, S.E., Larson, M.C., Luk, H., Hernandez, B.Y., Thompson, P.J., Sherman, M.E., Bodelon, C., Lewsley, L.A., Banerjee, S.N., Stronach, E.A., Haluska, P., Ray-Coquard, I., Winterhoff, B., Slamon, D., Levine, D.A., Menon, U., Goodman, M.T., Schildkraut, J.M., Brown, R., Berchuck, A., Chenevix-Trench, G., deFazio, A., Beeghly-Fadiel, A., Fasching, P.A., Orsulic, S.
Published in Annals of oncology

Implementation of evidence-based practices in state mental health systems: implications for research and effectiveness studies

by Ganju, Vijay
Published in Schizophrenia bulletin

Adjuvant Chemotherapy With Fluorouracil Plus Folinic Acid vs Gemcitabine Following Pancreatic Cancer Resection: A Randomized Controlled Trial

by Neoptolemos, John P, Stocken, Deborah D, Bassi, Claudio, Ghaneh, Paula, Cunningham, David, Goldstein, David, Padbury, Robert, Moore, Malcolm J, Gallinger, Steven, Mariette, Christophe, Wente, Moritz N, Izbicki, Jakob R, Friess, Helmut, Lerch, Markus M, Dervenis, Christos, Oláh, Attila, Butturini, Giovanni, Doi, Ryuichiro, Lind, Pehr A, Smith, David, Valle, Juan W, Palmer, Daniel H, Buckels, John A, Thompson, Joyce, McKay, Colin J, Rawcliffe, Charlotte L, Büchler, Markus W, European Study Group for Pancreatic Cancer, for the
Published in JAMA : the journal of the American Medical Association

Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised control...

by Nordlinger, Bernard, Prof, Sorbye, Halfdan, MD, Glimelius, Bengt, Prof, Poston, Graeme J, MD, Schlag, Peter M, Prof, Rougier, Philippe, Prof, Bechstein, Wolf O, Prof, Primrose, John N, Prof, Walpole, Euan T, MD, Finch-Jones, Meg, MD, Jaeck, Daniel, MD, Mirza, Darius, MD, Parks, Rowan W, MD, Collette, Laurence, PhD, Praet, Michel, ScD, Bethe, Ullrich, MD, Van Cutsem, Eric, MD, Scheithauer, Werner, MD, Gruenberger, Thomas, Prof
Published in The Lancet (British edition)

A phase I trial of Capecitabine+Gemcitabine with radical radiation for locally advanced pancreatic cancer

by MICHAEL, M, PRICE, T, ZALCBERG, J. R, LEONG, T, NGAN, S. Y, GANJU, V, STRICKLAND, A. H, MULLER, A, KHAMLY, K, MILNER, A. D, DILULIO, J, MATERA, A
Published in British journal of cancer

MA06.09 Preliminary Safety, Efficacy Results of KN046 (Bispecific Anti-PD-L1/CTLA4) in Subjects With Rare Thoracic Tumors

by Richardson, G., Kichenadasse, G., Ganju, V., Xu, J., Van, H., Kong, P., Yang, F., Wei, Y., Lu, Y., Guo, K., Donato, L., Xu, T., Coward, J.
Published in Journal of thoracic oncology

Caspase Activation and Response to Neo-Adjuvant Chemotherapy (Nac) in Locally Advanced Breast Cancer (Labc)

by Geddes, K., Alamgeer, M., Fox, J., Kumar, B., Ganju, V.
Published in Annals of oncology

ABCA transporter gene expression and poor outcome in epithelial ovarian cancer

by Hedditch, Ellen L, Gao, Bo, Russell, Amanda J, Lu, Yi, Emmanuel, Catherine, Beesley, Jonathan, Johnatty, Sharon E, Chen, Xiaoqing, Harnett, Paul, George, Joshy, Williams, Rebekka T, Flemming, Claudia, Lambrechts, Diether, Despierre, Evelyn, Lambrechts, Sandrina, Vergote, Ignace, Karlan, Beth, Lester, Jenny, Orsulic, Sandra, Walsh, Christine, Fasching, Peter, Beckmann, Matthias W, Ekici, Arif B, Hein, Alexander, Matsuo, Keitaro, Hosono, Satoyo, Nakanishi, Toru, Yatabe, Yasushi, Pejovic, Tanja, Bean, Yukie, Heitz, Florian, Harter, Philipp, du Bois, Andreas, Schwaab, Ira, Hogdall, Estrid, Kjaer, Susan K, Jensen, Allan, Hogdall, Claus, Lundvall, Lene, Engelholm, Svend Aage, Brown, Bob, Flanagan, James, Metcalf, Michelle D, Siddiqui, Nadeem, Sellers, Thomas, Fridley, Brooke, Cunningham, Julie, Schildkraut, Joellen, Iversen, Ed, Weber, Rachel P, Berchuck, Andrew, Goode, Ellen, Bowtell, David D, Chenevix-Trench, Georgia, deFazio, Anna, Norris, Murray D, MacGregor, Stuart, Haber, Michelle, Henderson, Michelle J
Published in JNCI : Journal of the National Cancer Institute

Refined cut-off for TP53 immunohistochemistry improves prediction of TP53 mutation status in ovarian mucinous tumors: implications for outcome analyses

by Cheasley, Dane, da Cunha Torres, Michelle, Salazar, Carolina, Xing, Zhongyue, Mes-Masson, Anne-Marie, Provencher, Diane M., Rahimi, Kurosh, Fasching, Peter A., Goodman, Marc T., Deen, Suha, Sieh, Weiva, Mateoiu, Constantina, Cook, Linda S., Le, Nhu D., Anglesio, Michael S., Chenevix-Trench, G., Traficante, N., Harrap, K., Sadkowsky, T., Mellon, A., Jones, M., Green, L., Ranieri, B., White, J., Bowes, L., Galletta, L., Giles, D., Hendley, J., Alsop, K., Young, C., Viduka, S., Glavinas, Lydia, Rutovitz, J., Glasgow, A., Bonaventura, T., Begbie, S., Baron-Hay, S., Nevell, D., Valmadre, S., Marsden, D., Beale, P., Beith, J., Carter, J., Dalrymple, C., Brand, A., Byth, K., Jaworski, R., Papadimos, D., Crandon, A., Cummings, M., Horwood, K., Perrin, L., Wyld, D., Davy, M., Oehler, M.K., Hall, C., Henderson, D., Miller, J., Blomfield, P., Rome, R., Grant, P., Laurie, R., Robbie, M., Manolitsas, T., McNealage, J., Susil, B., Sumithran, E., Phillips, K., Rischin, D., Fox, S., Loughrey, M., Billson, V., Neesham, D., Quinn, M., Blum, R., Leung, Y., Buck, M., Purdie, D., Ramus, Susan J., Scott, Clare L., Köbel, Martin, Gorringe, Kylie L., Allan, Prue E., Böhm, Maret, Christie, Michael, DeFazio, Anna, Fairweather, Nicole, Hadley, Alison M., Hendley, Joy, Ho, Gwo-Yaw, Huntsman, David G., Jobling, Tom W., Kennedy, Catherine J., Le Page, Cecile, Pyman, Jan, Rahimi, Kurosh, Samimi, Goli, Sharma, Ragwha, Antill, Yoland C., Gorringe, Kylie L.
Published in Modern pathology

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

by Song, Honglin, Lawrenson, Kate, Ramus, Susan J, Cicek, Mine S, Tyrer, Jonathan, Stram, Douglas, Wozniak, Eva L, Wik, Elisabeth, Whittemore, Alice S, Weber, Rachel Palmieri, Vitonis, Allison F, Vergote, Ignace, Van Den Berg, David, Van Altena, Anne M, Tworoger, Shelley S, Thompson, Pamela J, Tessier, Daniel C, Teo, Soo-Hwang, Templeman, Claire, Stram, Daniel O, Southey, Melissa C, Siddiqui, Nadeem, Shu, Xiao-Ou, Shridhar, Viji, Severi, Gianluca, Schwaab, Ira, Rzepecka, Iwona K, Runnebaum, Ingo B, Rossing, Mary Anne, Rodriguez-Rodriguez, Lorna, Renner, Stefan P, Poole, Elizabeth M, Pike, Malcolm C, Pelttari, Liisa M, Pejovic, Tanja, Paul, James, Orlow, Irene, Odunsi, Kunle, Nevanlinna, Heli, Ness, Roberta B, Nakanishi, Toru, Moysich, Kirsten B, Monteiro, Alvaro N A, Moes-Sosnowska, Joanna, Modugno, Francesmary, Menon, Usha, Massuger, Leon F A G, Lundvall, Lene, Lissowska, Jolanta, Kupryjanczyk, Jolanta, Krakstad, Camilla, Konecny, Gottfried E, Kjaer, Susanne Krüger, Kiemeney, Lambertus A, Karlan, Beth Y, Karevan, Rod, Kalli, Kimberly R, Kajiyama, Hiroaki, Ji, Bu-Tian, Høgdall, Claus K, Hoatlin, Maureen, Hein, Rebecca, Hall, Per, Gronwald, Jacek, Gore, Martin, Goodman, Marc T, Giles, Graham G, Gentry-Maharaj, Aleksandra, Garcia-Closas, Montserrat, Flanagan, James M, Fasching, Peter A, Ekici, Arif B, Edwards, Robert, Eccles, Diana, Easton, Douglas F, Dürst, Matthias, du Bois, Andreas, Dörk, Thilo, Despierre, Evelyn, Cramer, Daniel W, Cook, Linda S, Chen, Xiaoqing, Charbonneau, Bridget, Chang-Claude, Jenny, Bunker, Clareann H, Brueggmann, Doerthe, Brown, Robert, Brooks-Wilson, Angela, Brinton, Louise A, Bogdanova, Natalia, Beesley, Jonathan, Beckmann, Matthias W, Baglietto, Laura, Bacot, François, Armasu, Sebastian M, Antonenkova, Natalia, Wu, Xifeng, Hildebrandt, Michelle A T, Sellers, Thomas A, Pearce, Celeste Leigh
Published in Nature communications

Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers

by Helland, Åslaug, Anglesio, Michael S, George, Joshy, Cowin, Prue A, Johnstone, Cameron N, House, Colin M, Sheppard, Karen E, Etemadmoghadam, Dariush, Melnyk, Nataliya, Rustgi, Anil K, Phillips, Wayne A, Johnsen, Hilde, Holm, Ruth, Kristensen, Gunnar B, Birrer, Michael J, Pearson, Richard B, Børresen-Dale, Anne-Lise, Huntsman, David G, deFazio, Anna, Creighton, Chad J, Smyth, Gordon K, Bowtell, David D L
Published in PloS one