Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer

by Kreso, Antonija, O'Brien, Catherine A., van Galen, Peter, Gan, Olga I., Notta, Faiyaz, Brown, Andrew M. K., Ng, Karen, Ma, Jing, Wienholds, Erno, Dunant, Cyrille, Pollett, Aaron, Gallinger, Steven, McPherson, John, Mullighan, Charles G., Shibata, Darryl, Dick, John E.
Published in Science (American Association for the Advancement of Science)

Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer

by Win, Aung Ko, Jenkins, Mark A, Dowty, James G, Antoniou, Antonis C, Lee, Andrew, Giles, Graham G, Buchanan, Daniel D, Clendenning, Mark, Rosty, Christophe, Ahnen, Dennis J, Thibodeau, Stephen N, Casey, Graham, Gallinger, Steven, Le Marchand, Loïc, Haile, Robert W, Potter, John D, Zheng, Yingye, Lindor, Noralane M, Newcomb, Polly A, Hopper, John L, MacInnis, Robert J
Published in Cancer epidemiology, biomarkers & prevention

The New Era of Transplant Oncology: Liver Transplantation for Nonresectable Colorectal Cancer Liver Metastases

by Gorgen, Andre, Muaddi, Hala, Zhang, Wei, McGilvray, Ian, Gallinger, Steven, Sapisochin, Gonzalo
Published in Canadian journal of gastroenterology & hepatology

Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival

by Zaidi, Syed H, Harrison, Tabitha A, Phipps, Amanda I, Steinfelder, Robert, Trinh, Quang M, Qu, Conghui, Banbury, Barbara L, Georgeson, Peter, Grasso, Catherine S, Giannakis, Marios, Adams, Jeremy B, Alwers, Elizabeth, Amitay, Efrat L, Barfield, Richard T, Berndt, Sonja I, Borozan, Ivan, Brenner, Hermann, Brezina, Stefanie, Buchanan, Daniel D, Cao, Yin, Chan, Andrew T, Chang-Claude, Jenny, Connolly, Charles M, Drew, David A, Farris, 3rd, Alton Brad, Figueiredo, Jane C, French, Amy J, Fuchs, Charles S, Garraway, Levi A, Gruber, Steve, Guinter, Mark A, Hamilton, Stanley R, Harlid, Sophia, Heisler, Lawrence E, Hidaka, Akihisa, Hopper, John L, Huang, Wen-Yi, Huyghe, Jeroen R, Jenkins, Mark A, Krzyzanowski, Paul M, Lemire, Mathieu, Lin, Yi, Luo, Xuemei, Mardis, Elaine R, McPherson, John D, Miller, Jessica K, Moreno, Victor, Mu, Xinmeng Jasmine, Nishihara, Reiko, Papadopoulos, Nickolas, Pasternack, Danielle, Quist, Michael J, Rafikova, Adilya, Reid, Emma E G, Shinbrot, Eve, Shirts, Brian H, Stein, Lincoln D, Teney, Cherie D, Timms, Lee, Um, Caroline Y, Van Guelpen, Bethany, Van Tassel, Megan, Wang, Xiaolong, Wheeler, David A, Yung, Christina K, Hsu, Li, Ogino, Shuji, Gsur, Andrea, Newcomb, Polly A, Gallinger, Steven, Hoffmeister, Michael, Campbell, Peter T, Thibodeau, Stephen N, Sun, Wei, Hudson, Thomas J, Peters, Ulrike
Published in Nature communications

Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis

by Yarmolinsky, James, Díez-Obrero, Virginia, Richardson, Tom G, Pigeyre, Marie, Sjaarda, Jennifer, Paré, Guillaume, Walker, Venexia M, Vincent, Emma E, Tan, Vanessa Y, Obón-Santacana, Mireia, Albanes, Demetrius, Hampe, Jochen, Gsur, Andrea, Hampel, Heather, Pai, Rish K, Jenkins, Mark, Gallinger, Steven, Casey, Graham, Zheng, Wei, Amos, Christopher I, Smith, George Davey, Martin, Richard M, Moreno, Victor
Published in PLoS medicine

Genome-wide association study identifies tumor anatomical site-specific risk variants for colorectal cancer survival

by Labadie, Julia D, Savas, Sevtap, Harrison, Tabitha A, Banbury, Barb, Huang, Yuhan, Buchanan, Daniel D, Campbell, Peter T, Gallinger, Steven J, Giles, Graham G, Gunter, Marc J, Hoffmeister, Michael, Hsu, Li, Jenkins, Mark A, Lin, Yi, Ogino, Shuji, Phipps, Amanda I, Slattery, Martha L, Steinfelder, Robert S, Sun, Wei, Van Guelpen, Bethany, Hua, Xinwei, Figuieredo, Jane C, Pai, Rish K, Nassir, Rami, Qi, Lihong, Chan, Andrew T, Peters, Ulrike, Newcomb, Polly A
Published in Scientific reports

Identifying colorectal cancer caused by biallelic MUTYH pathogenic variants using tumor mutational signatures

by Georgeson, Peter, Harrison, Tabitha A, Pope, Bernard J, Zaidi, Syed H, Qu, Conghui, Steinfelder, Robert S, Lin, Yi, Joo, Jihoon E, Mahmood, Khalid, Clendenning, Mark, Walker, Romy, Amitay, Efrat L, Berndt, Sonja I, Brenner, Hermann, Campbell, Peter T, Cao, Yin, Chan, Andrew T, Chang-Claude, Jenny, Doheny, Kimberly F, Drew, David A, Figueiredo, Jane C, French, Amy J, Gallinger, Steven, Giannakis, Marios, Giles, Graham G, Gsur, Andrea, Gunter, Marc J, Hoffmeister, Michael, Hsu, Li, Huang, Wen-Yi, Limburg, Paul, Manson, JoAnn E, Moreno, Victor, Nassir, Rami, Nowak, Jonathan A, Obón-Santacana, Mireia, Ogino, Shuji, Phipps, Amanda I, Potter, John D, Schoen, Robert E, Sun, Wei, Toland, Amanda E, Trinh, Quang M, Ugai, Tomotaka, Macrae, Finlay A, Rosty, Christophe, Hudson, Thomas J, Jenkins, Mark A, Thibodeau, Stephen N, Winship, Ingrid M, Peters, Ulrike, Buchanan, Daniel D
Published in Nature communications

Meta-analysis of new genome-wide association studies of colorectal cancer risk

by Peters, Ulrike, Hutter, Carolyn M., Hsu, Li, Schumacher, Fredrick R., Conti, David V., Carlson, Christopher S., Edlund, Christopher K., Haile, Robert W., Gallinger, Steven, Zanke, Brent W., Lemire, Mathieu, Rangrej, Jagadish, Vijayaraghavan, Raakhee, Chan, Andrew T., Hazra, Aditi, Hunter, David J., Ma, Jing, Fuchs, Charles S., Giovannucci, Edward L., Kraft, Peter, Liu, Yan, Chen, Lin, Jiao, Shuo, Makar, Karen W., Taverna, Darin, Gruber, Stephen B., Rennert, Gad, Moreno, Victor, Ulrich, Cornelia M., Woods, Michael O., Green, Roger C., Parfrey, Patrick S., Prentice, Ross L., Kooperberg, Charles, Jackson, Rebecca D., LaCroix, Andrea Z., Caan, Bette J., Hayes, Richard B., Berndt, Sonja I., Chanock, Stephen J., Schoen, Robert E., Chang-Claude, Jenny, Hoffmeister, Michael, Brenner, Hermann, Frank, Bernd, Bézieau, Stéphane, Küry, Sébastien, Slattery, Martha L., Hopper, John L., Jenkins, Mark A., Le Marchand, Loic, Lindor, Noralane M., Newcomb, Polly A., Seminara, Daniela, Hudson, Thomas J., Duggan, David J., Potter, John D., Casey, Graham
Published in Human genetics

Circulating bilirubin levels and risk of colorectal cancer: serological and Mendelian randomization analyses

by Seyed Khoei, Nazlisadat, Jenab, Mazda, Murphy, Neil, Banbury, Barbara L, Carreras-Torres, Robert, Viallon, Vivian, Kühn, Tilman, Bueno-de-Mesquita, Bas, Aleksandrova, Krasimira, Cross, Amanda J, Weiderpass, Elisabete, Stepien, Magdalena, Bulmer, Andrew, Tjønneland, Anne, Boutron-Ruault, Marie-Christine, Severi, Gianluca, Carbonnel, Franck, Katzke, Verena, Boeing, Heiner, Bergmann, Manuela M, Trichopoulou, Antonia, Karakatsani, Anna, Martimianaki, Georgia, Palli, Domenico, Tagliabue, Giovanna, Panico, Salvatore, Tumino, Rosario, Sacerdote, Carlotta, Skeie, Guri, Merino, Susana, Bonet, Catalina, Rodríguez-Barranco, Miguel, Gil, Leire, Chirlaque, Maria-Dolores, Ardanaz, Eva, Myte, Robin, Hultdin, Johan, Perez-Cornago, Aurora, Aune, Dagfinn, Tsilidis, Konstantinos K, Albanes, Demetrius, Baron, John A, Berndt, Sonja I, Bézieau, Stéphane, Brenner, Hermann, Campbell, Peter T, Casey, Graham, Chan, Andrew T, Chang-Claude, Jenny, Chanock, Stephen J, Cotterchio, Michelle, Gallinger, Steven, Gruber, Stephen B, Haile, Robert W, Hampe, Jochen, Hoffmeister, Michael, Hopper, John L, Hsu, Li, Huyghe, Jeroen R, Jenkins, Mark A, Joshi, Amit D, Kampman, Ellen, Larsson, Susanna C, Le Marchand, Loic, Li, Christopher I, Li, Li, Lindblom, Annika, Lindor, Noralane M, Martín, Vicente, Moreno, Victor, Newcomb, Polly A, Offit, Kenneth, Ogino, Shuji, Parfrey, Patrick S, Pharoah, Paul D P, Rennert, Gad, Sakoda, Lori C, Schafmayer, Clemens, Schmit, Stephanie L, Schoen, Robert E, Slattery, Martha L, Thibodeau, Stephen N, Ulrich, Cornelia M, van Duijnhoven, Franzel J B, Weigl, Korbinian, Weinstein, Stephanie J, White, Emily, Wolk, Alicja, Woods, Michael O, Wu, Anna H, Zhang, Xuehong, Ferrari, Pietro, Anton, Gabriele, Peters, Annette, Peters, Ulrike, Gunter, Marc J, Wagner, Karl-Heinz, Freisling, Heinz
Published in BMC medicine

Prediction of Germline Mutations and Cancer Risk in the Lynch Syndrome

by Chen, Sining, Wang, Wenyi, Lee, Shing, Nafa, Khedoudja, Lee, Johanna, Romans, Kathy, Watson, Patrice, Gruber, Stephen B, Euhus, David, Kinzler, Kenneth W, Jass, Jeremy, Gallinger, Steven, Lindor, Noralane M, Casey, Graham, Ellis, Nathan, Giardiello, Francis M, Offit, Kenneth, Parmigiani, Giovanni, Colon Cancer Family Registry, for the
Published in JAMA : the journal of the American Medical Association

Characterization of Gene―Environment Interactions for Colorectal Cancer Susceptibility Loci

by HUTTER, Carolyn M, CHANG-CLAUDE, Jenny, SHUO JIAO, HARRISON, Tabitha A, YAN LIU, CHEN, Lin S, STELLING, Deanna L, WARNICK, Greg S, HOFFMEISTER, Michael, KÜRY, Sébastien, FUCHS, Charles S, GIOVANNUCCI, Edward, SLATTERY, Martha L, HAZRA, Aditi, KRAFT, Peter, HUNTER, David J, GALLINGER, Steven, ZANKE, Brent W, BRENNER, Hermann, FRANK, Bernd, JING MA, ULRICH, Cornelia M, WHITE, Emily, PFLUGEISEN, Bethann M, NEWCOMB, Polly A, KOOPERBERG, Charles, LACROIX, Andrea Z, PRENTICE, Ross L, JACKSON, Rebecca D, SCHOEN, Robert E, CHANOCK, Stephen J, BERNDT, Sonja I, HAYES, Richard B, CAAN, Bette J, YI LIN, POTTER, John D, HSU, Li, BEZIEAU, Stéphane, CHAN, Andrew T, HUDSON, Thomas J, PETERS, Ulrike, DUGGAN, David, HONGMEI NAN, LEMIRE, Mathieu, RANGREJ, Jagadish, FIGUEIREDO, Jane C
Published in Cancer research (Chicago, Ill.)

Juvenile polyposis, hereditary hemorrhagic telangiectasia, and early onset colorectal cancer in patients with SMAD4 mutation

by Schwenter, Frank, Faughnan, Marie E., Gradinger, Abigail B., Berk, Terri, Gryfe, Robert, Pollett, Aaron, Cohen, Zane, Gallinger, Steven, Durno, Carol
Published in Journal of gastroenterology

Association of Body Mass Index With Colorectal Cancer Risk by Genome-Wide Variants

by Campbell, Peter T, Lin, Yi, Bien, Stephanie A, Figueiredo, Jane C, Harrison, Tabitha A, Guinter, Mark A, Berndt, Sonja I, Brenner, Hermann, Chan, Andrew T, Chang-Claude, Jenny, Gallinger, Steven J, Gapstur, Susan M, Giles, Graham G, Giovannucci, Edward, Gruber, Stephen B, Gunter, Marc, Hoffmeister, Michael, Jacobs, Eric J, Jenkins, Mark A, Le Marchand, Loic, Li, Li, McLaughlin, John R, Murphy, Neil, Milne, Roger L, Newcomb, Polly A, Newton, Christina, Ogino, Shuji, Potter, John D, Rennert, Gad, Rennert, Hedy S, Robinson, Jennifer, Sakoda, Lori C, Slattery, Martha L, Song, Yiqing, White, Emily, Woods, Michael O, Casey, Graham, Hsu, Li, Peters, Ulrike
Published in JNCI : Journal of the National Cancer Institute

Risk of Metachronous Colon Cancer Following Surgery for Rectal Cancer in Mismatch Repair Gene Mutation Carriers

by Win, Aung Ko, Parry, Susan, Parry, Bryan, Kalady, Matthew F., Macrae, Finlay A., Ahnen, Dennis J., Young, Graeme P., Lipton, Lara, Winship, Ingrid, Boussioutas, Alex, Young, Joanne P., Buchanan, Daniel D., Arnold, Julie, Le Marchand, Loïc, Newcomb, Polly A., Haile, Robert W., Lindor, Noralane M., Gallinger, Steven, Hopper, John L., Jenkins, Mark A.
Published in Annals of surgical oncology

Genome-wide diet-gene interaction analyses for risk of colorectal cancer

by Figueiredo, Jane C, Hsu, Li, Hutter, Carolyn M, Lin, Yi, Campbell, Peter T, Baron, John A, Berndt, Sonja I, Jiao, Shuo, Casey, Graham, Fortini, Barbara, Chan, Andrew T, Cotterchio, Michelle, Lemire, Mathieu, Gallinger, Steven, Harrison, Tabitha A, Le Marchand, Loic, Newcomb, Polly A, Slattery, Martha L, Caan, Bette J, Carlson, Christopher S, Zanke, Brent W, Rosse, Stephanie A, Brenner, Hermann, Giovannucci, Edward L, Wu, Kana, Chang-Claude, Jenny, Chanock, Stephen J, Curtis, Keith R, Duggan, David, Gong, Jian, Haile, Robert W, Hayes, Richard B, Hoffmeister, Michael, Hopper, John L, Jenkins, Mark A, Kolonel, Laurence N, Qu, Conghui, Rudolph, Anja, Schoen, Robert E, Schumacher, Fredrick R, Seminara, Daniela, Stelling, Deanna L, Thibodeau, Stephen N, Thornquist, Mark, Warnick, Greg S, Henderson, Brian E, Ulrich, Cornelia M, Gauderman, W James, Potter, John D, White, Emily, Peters, Ulrike
Published in PLoS genetics

Prognostic role of detailed colorectal location and tumor molecular features: analyses of 13,101 colorectal cancer patients including 2994 early-onset cases

by Ugai, Tomotaka, Akimoto, Naohiko, Haruki, Koichiro, Harrison, Tabitha A., Cao, Yin, Qu, Conghui, Chan, Andrew T., Campbell, Peter T., Berndt, Sonja I., Buchanan, Daniel D., Cross, Amanda J., Diergaarde, Brenda, Gallinger, Steven J., Gunter, Marc J., Harlid, Sophia, Hidaka, Akihisa, Hoffmeister, Michael, Brenner, Hermann, Chang-Claude, Jenny, Hsu, Li, Jenkins, Mark A., Lin, Yi, Milne, Roger L., Moreno, Victor, Newcomb, Polly A., Nishihara, Reiko, Obon-Santacana, Mireia, Pai, Rish K., Sakoda, Lori C., Schoen, Robert E., Slattery, Martha L., Sun, Wei, Amitay, Efrat L., Alwers, Elizabeth, Thibodeau, Stephen N., Toland, Amanda E., Van Guelpen, Bethany, Zaidi, Syed H., Potter, John D., Meyerhardt, Jeffrey A., Giannakis, Marios, Song, Mingyang, Nowak, Jonathan A., Peters, Ulrike, Phipps, Amanda I., Ogino, Shuji
Published in Journal of gastroenterology

A framework to build capacity for a reflex-testing program for Lynch syndrome

by Palter, Vanessa N, Baker, Natalie A, Rabeneck, Linda, Tinmouth, Jill, Gagliardi, Anna R, Kennedy, Erin D, Carroll, June C, Gallinger, Steven, Baxter, Nancy N
Published in Genetics in medicine

Molecular Characterization of MSI-H Colorectal Cancer by MLHI Promoter Methylation, Immunohistochemistry, and Mismatch Repair Germline Mutation Screening

by Poynter, Jenny N, Siegmund, Kimberly D, Weisenberger, Daniel J, Long, Tiffany I, Thibodeau, Stephen N, Lindor, Noralane, Young, Joanne, Jenkins, Mark A, Hopper, John L, Baron, John A, Buchanan, Dan, Casey, Graham, Levine, A Joan, Le Marchand, Loïc, Gallinger, Steven, Bapat, Bharati, Potter, John D, Newcomb, Polly A, Haile, Robert W, Laird, Peter W
Published in Cancer epidemiology, biomarkers & prevention

Genetic variants in vitamin d pathway genes and risk of pancreas cancer; results from a population-based case-control study in ontario, Canada

by Anderson, Laura N, Cotterchio, Michelle, Knight, Julia A, Borgida, Ayelet, Gallinger, Steven, Cleary, Sean P
Published in PloS one

Case–Control Study of Overweight, Obesity, and Colorectal Cancer Risk, Overall and by Tumor Microsatellite Instability Status

by Campbell, Peter T., Jacobs, Elizabeth T., Ulrich, Cornelia M., Figueiredo, Jane C., Poynter, Jenny N., McLaughlin, John R., Haile, Robert W., Jacobs, Eric J., Newcomb, Polly A., Potter, John D., Le Marchand, Loïc, Green, Roger C., Parfrey, Patrick, Younghusband, H. Banfield, Cotterchio, Michelle, Gallinger, Steven, Jenkins, Mark A., Hopper, John L., Baron, John A., Thibodeau, Stephen N., Lindor, Noralane M., Limburg, Paul J., Martínez, María Elena
Published in JNCI : Journal of the National Cancer Institute