Regulation, Reimbursement, and the Long Road of Implementation of Personalized Medicine—A Perspective from the United States

by Frueh, Felix W., PhD
Published in Value in health

The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies

by Shi, Leming, Jones, Wendell D, Jensen, Roderick V, Harris, Stephen C, Perkins, Roger G, Goodsaid, Federico M, Guo, Lei, Croner, Lisa J, Boysen, Cecilie, Fang, Hong, Qian, Feng, Amur, Shashi, Bao, Wenjun, Barbacioru, Catalin C, Bertholet, Vincent, Cao, Xiaoxi Megan, Chu, Tzu-Ming, Collins, Patrick J, Fan, Xiao-Hui, Frueh, Felix W, Fuscoe, James C, Guo, Xu, Han, Jing, Herman, Damir, Hong, Huixiao, Kawasaki, Ernest S, Li, Quan-Zhen, Luo, Yuling, Ma, Yunqing, Mei, Nan, Peterson, Ron L, Puri, Raj K, Shippy, Richard, Su, Zhenqiang, Sun, Yongming Andrew, Sun, Hongmei, Thorn, Brett, Turpaz, Yaron, Wang, Charles, Wang, Sue Jane, Warrington, Janet A, Willey, James C, Wu, Jie, Xie, Qian, Zhang, Liang, Zhang, Lu, Zhong, Sheng, Wolfinger, Russell D, Tong, Weida
Published in BMC bioinformatics

Strategic paths for biomarker qualification

by Goodsaid, Federico M, Frueh, Felix W, Mattes, William
Published in Toxicology (Amsterdam)

Impact of microarray data quality on genomic data submissions to the FDA

by Frueh, Felix W
Published in Nature biotechnology

Cross-platform comparability of microarray technology: intra-platform consistency and appropriate data analysis procedures are essential

by Shi, Leming, Tong, Weida, Fang, Hong, Scherf, Uwe, Han, Jing, Puri, Raj K, Frueh, Felix W, Goodsaid, Federico M, Guo, Lei, Su, Zhenqiang, Han, Tao, Fuscoe, James C, Xu, Z Alex, Patterson, Tucker A, Hong, Huixiao, Xie, Qian, Perkins, Roger G, Chen, James J, Casciano, Daniel A
Published in BMC bioinformatics

Microarray scanner calibration curves: characteristics and implications

by Shi, Leming, Tong, Weida, Su, Zhenqiang, Han, Tao, Han, Jing, Puri, Raj K, Fang, Hong, Frueh, Felix W, Goodsaid, Federico M, Guo, Lei, Branham, William S, Chen, James J, Xu, Z Alex, Harris, Stephen C, Hong, Huixiao, Xie, Qian, Perkins, Roger G, Fuscoe, James C
Published in BMC bioinformatics

Use of cDNA microarrays to analyze dioxin-induced changes in human liver gene expression

by Frueh, Felix W, Hayashibara, Kathleen C, Brown, Patrick O, Whitlock, James P
Published in Toxicology letters

On rat poison and human medicines: personalizing warfarin therapy

by Frueh, Felix W
Published in Trends in molecular medicine

Evidence of clinical utility: an unmet need in molecular diagnostics for patients with cancer

by Parkinson, David R, McCormack, Robert T, Keating, Susan M, Gutman, Steven I, Hamilton, Stanley R, Mansfield, Elizabeth A, Piper, Margaret A, Deverka, Patricia, Frueh, Felix W, Jessup, J Milburn, McShane, Lisa M, Tunis, Sean R, Sigman, Caroline C, Kelloff, Gary J
Published in Clinical cancer research

Physician Awareness and Utilization of Food and Drug Administration (FDA)-Approved Labeling for Pharmacogenomic Testing Information

by Stanek, Eric J, Sanders, Christopher L, Frueh, Felix W
Published in Journal of personalized medicine

Considerations for safety pharmacogenetics in clinical practice

by Frueh, Felix W.
Published in Drug discovery today

PATIENT KNOWLEDGE OF PHARMACOGENETIC INFORMATION IMPROVES ADHERENCE TO STATIN THERAPY: RESULTS OF THE ADDITIONAL KIF6 RISK OFFERS BETTER ADHERENCE TO STATINS (AKROBATS) TRIAL

by Charland, Scott L, Agatep, Barnabie C, Epstein, Robert S, Frueh, Felix W, Herrera, Vivian, Devlin, James, Superko, H, Stanek, Eric J
Published in Journal of the American College of Cardiology

Qualification of Biomarkers for Drug Development in Organ Transplantation

by Burckart, Gilbert J., Amur, Shashi, Goodsaid, Federico M., Lesko, Lawrence J., Frueh, Felix W., Huang, Shiew‐Mei, Cavaille‐Coll, Marc W.
Published in American journal of transplantation

A NATIONWIDE SURVEY OF ADOPTION AND PERCEPTION OF PHARMACOGENOMIC TESTING BY U.S. CARDIOLOGISTS

by Stanek, Eric, Sanders, Christopher L, Agatep, Barnabie C, Johansen, Katherine A, Aubert, Ronald E, Khalid, Mona, Patel, Aanal, Frueh, Felix W, Epstein, Robert S
Published in Journal of the American College of Cardiology

The Predictive Safety Testing Consortium: A synthesis of the goals, challenges and accomplishments of the Critical Path

by Goodsaid, Federico M., Frueh, Felix W., Mattes, William
Published in Drug discovery today. Technologies

Regulatory Acceptance of Toxicogenomics Data

by Frueh, Felix W., Huang, Shiew-Mei, Lesko, Lawrence J.
Published in Environmental health perspectives

In Situ Synthesis of Oligonucleotide Arrays by Using Surface Tension

by Butler, John H, Cronin, Maureen, Anderson, Keith M, Biddison, Giles M, Chatelain, Francois, Cummer, Michael, Davi, Deborah J, Fisher, Lawson, Frauendorf, Albrecht W, Frueh, Felix W, Gjerstad, Carmen, Harper, Theresa F, Kernahan, Stephanie D, Long, Danny Q, Pho, Mylan, Walker, John A, Brennan, Thomas M
Published in Journal of the American Chemical Society

Considerations for safety pharmacogenetics in clinical practice: Pharmacogenetics and stratified medicine

by FRUEH, Felix W
Published in Drug discovery today

Questions and answers about the Pilot Process for Biomarker Qualification at the FDA

by Goodsaid, Federico M., Frueh, Felix W.
Published in Drug discovery today. Technologies

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

by Shi, Leming, Reid, Laura H, Jones, Wendell D, Warrington, Janet A, Baker, Shawn C, Collins, Patrick J, de Longueville, Francoise, Lee, Kathleen Y, Luo, Yuling, Sun, Yongming Andrew, Willey, James C, Setterquist, Robert A, Fischer, Gavin M, Tong, Weida, Dragan, Yvonne P, Frueh, Felix W, Goodsaid, Frederico M, Herman, Damir, Jensen, Roderick V, Johnson, Charles D, Puri, Raj K, Schrf, Uwe, Wolber, Paul K, Zhang, Lu, Amur, Shashi, Bao, Wenjun, Barbacioru, Catalin C, Lucas, Anne Bergstrom, Bertholet, Vincent, Bromley, Bud, Brunner, Alan, Canales, Roger, Cao, Xiaoxi Megan, Cebula, Thomas A, Chen, James J, Cheng, Jing, Chu, Tzu-Ming, Chudin, Eugene, Corson, John, Corton, J Christopher, Davies, Christopher, Davison, Timothy S, Delenstarr, Glenda, Deng, Xutao, Dorris, David, Eklund, Aron C, Fan, Xiao-hui, Fulmer-Smentek, Stephanie, Fuscoe, James C, Gallagher, Kathryn, Ge, Weigong, Hager, Janet, Han, Jing, Han, Tao, Harbottle, Heather C, Harris, Stephen C, Hatchwell, Eli, Hauser, Craig A, Hester, Susan, Hong, Huixiao, Jackson, Scott A, Ji, Hanlee, Knight, Charles R, Kuo, Winston P, Levy, Shawn, Li, Quan-Zhen, Liu, Ying, Ma, Yunqing, Magnuson, Scott R, McDaniel, Tim, Mei, Nan, Ning, Baitang, Novoradovskaya, Natalia, Orr, Michael S, Osborn, Terry W, Patterson, Tucker A, Perkins, Roger G, Peters, Elizabeth H, Peterson, Ron, Philips, Kenneth L, Pine, P Scott, Ren, Hongzu, Rosen, Mitch, Schena, Mark, Smith, Dave D, Staedtler, Frank, Sun, Hongmei, Szallasi, Zoltan, Tezak, Zivana, Thierry-Mieg, Danielle, Thompson, Karol L, Tikhonova, Irina, Turpaz, Yaron, Vallanat, Beena, Van, Christophe, Walker, Stephen J, Wang, Yonghong, Wolfinger, Russ, Wu, Jie, Yang, Wen
Published in Nature biotechnology