CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling by Platt, Randall J., Chen, Sidi, Zhou, Yang, Yim, Michael J., Swiech, Lukasz, Kempton, Hannah R., Dahlman, James E., Parnas, Oren, Eisenhaure, Thomas M., Jovanovic, Marko, Graham, Daniel B., Jhunjhunwala, Siddharth, Heidenreich, Matthias, Xavier, Ramnik J., Langer, Robert, Anderson, Daniel G., Hacohen, Nir, Regev, Aviv, Feng, Guoping, Sharp, Phillip A., Zhang, Feng

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Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction by Abelin, Jennifer G., Keskin, Derin B., Sarkizova, Siranush, Hartigan, Christina R., Zhang, Wandi, Sidney, John, Stevens, Jonathan, Lane, William, Zhang, Guang Lan, Eisenhaure, Thomas M., Clauser, Karl R., Hacohen, Nir, Rooney, Michael S., Carr, Steven A., Wu, Catherine J.

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A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks by Parnas, Oren, Jovanovic, Marko, Eisenhaure, Thomas M., Herbst, Rebecca H., Dixit, Atray, Ye, Chun Jimmie, Przybylski, Dariusz, Platt, Randall J., Tirosh, Itay, Sanjana, Neville E., Shalem, Ophir, Satija, Rahul, Raychowdhury, Raktima, Mertins, Philipp, Carr, Steven A., Zhang, Feng, Hacohen, Nir, Regev, Aviv

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Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells by Lee, Mark N., Ye, Chun, Villani, Alexandra-Chloé, Raj, Towfique, Li, Weibo, Eisenhaure, Thomas M., Imboywa, Selina H., Chipendo, Portia I., Ran, F. Ann, Slowikowski, Kamil, Ward, Lucas D., Raddassi, Khadir, McCabe, Cristin, Lee, Michelle H., Frohlich, Irene Y., Hafler, David A., Kellis, Manolis, Raychaudhuri, Soumya, Zhang, Feng, Stranger, Barbara E., Benoist, Christophe O., De Jager, Philip L., Regev, Aviv, Hacohen, Nir

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A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen by Moffat, Jason, Grueneberg, Dorre A., Yang, Xiaoping, Kim, So Young, Kloepfer, Angela M., Hinkle, Gregory, Piqani, Bruno, Eisenhaure, Thomas M., Luo, Biao, Grenier, Jennifer K., Carpenter, Anne E., Foo, Shi Yin, Stewart, Sheila A., Stockwell, Brent R., Hacohen, Nir, Hahn, William C., Lander, Eric S., Sabatini, David M., Root, David E.

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Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits by Chevrier, Nicolas, Mertins, Philipp, Artyomov, Maxim N., Shalek, Alex K., Iannacone, Matteo, Ciaccio, Mark F., Gat-Viks, Irit, Tonti, Elena, DeGrace, Marciela M., Clauser, Karl R., Garber, Manuel, Eisenhaure, Thomas M., Yosef, Nir, Robinson, Jacob, Sutton, Amy, Andersen, Mette S., Root, David E., von Andrian, Ulrich, Jones, Richard B., Park, Hongkun, Carr, Steven A., Regev, Aviv, Amit, Ido, Hacohen, Nir

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An Integrative Framework Reveals Signaling-to-Transcription Events in Toll-like Receptor Signaling by Mertins, Philipp, Przybylski, Dariusz, Yosef, Nir, Qiao, Jana, Clauser, Karl, Raychowdhury, Raktima, Eisenhaure, Thomas M., Maritzen, Tanja, Haucke, Volker, Satoh, Takashi, Akira, Shizuo, Carr, Steven A., Regev, Aviv, Hacohen, Nir, Chevrier, Nicolas

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Cytotoxic CD4+ T cells eliminate senescent cells by targeting cytomegalovirus antigen by Hasegawa, Tatsuya, Oka, Tomonori, Son, Heehwa G., Oliver-García, Valeria S., Azin, Marjan, Eisenhaure, Thomas M., Lieb, David J., Hacohen, Nir, Demehri, Shadmehr

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A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression by Mahoney, Kathleen M., Shukla, Sachet A., Patsoukis, Nikolaos, Chaudhri, Apoorvi, Browne, Edward P., Arazi, Arnon, Eisenhaure, Thomas M., Pendergraft, William F., Hua, Ping, Pham, Hung C., Bu, Xia, Zhu, Baogong, Hacohen, Nir, Fritsch, Edward F., Boussiotis, Vassiliki A., Wu, Catherine J., Freeman, Gordon J.

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Systematic identification of genomic elements that regulate FCGR2A expression and harbor variants linked with autoimmune disease by Dahlqvist, Johanna, Fulco, Charles P, Ray, John P, Liechti, Thomas, de Boer, Carl G, Lieb, David J, Eisenhaure, Thomas M, Engreitz, Jesse M, Roederer, Mario, Hacohen, Nir

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Genome-wide enhancer maps link risk variants to disease genes by Nasser, Joseph, Bergman, Drew T, Fulco, Charles P, Guckelberger, Philine, Doughty, Benjamin R, Patwardhan, Tejal A, Jones, Thouis R, Nguyen, Tung H, Ulirsch, Jacob C, Lekschas, Fritz, Mualim, Kristy, Natri, Heini M, Weeks, Elle M, Munson, Glen, Kane, Michael, Kang, Helen Y, Cui, Ang, Ray, John P, Eisenhaure, Thomas M, Collins, Ryan L, Dey, Kushal, Pfister, Hanspeter, Price, Alkes L, Epstein, Charles B, Kundaje, Anshul, Xavier, Ramnik J, Daly, Mark J, Huang, Hailiang, Finucane, Hilary K, Hacohen, Nir, Lander, Eric S, Engreitz, Jesse M

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The Rho Guanine Nucleotide Exchange Factor Lsc Homo-oligomerizes and Is Negatively Regulated through Domains in Its Carboxyl Terminus That Are Absent in Novel Splenic Isoforms by Eisenhaure, Thomas M., Francis, Sanjeev A., Willison, L.David, Coughlin, Shaun R., Lerner, Daniel J.

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RNA Interference Screen in Primary Human T Cells Reveals FLT3 as a Modulator of IL-10 Levels by Astier, Anne L, Beriou, Gaelle, Eisenhaure, Thomas M, Anderton, Stephen M, Hafler, David A, Hacohen, Nir

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Notch signalling drives synovial fibroblast identity and arthritis pathology by Wei, Kevin, Korsunsky, Ilya, Marshall, Jennifer L, Gao, Anqi, Watts, Gerald F M, Major, Triin, Croft, Adam P, Watts, Jordan, Blazar, Philip E, Lange, Jeffrey K, Thornhill, Thomas S, Filer, Andrew, Raza, Karim, Donlin, Laura T, Siebel, Christian W, Buckley, Christopher D, Raychaudhuri, Soumya, Brenner, Michael B

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Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue by Donlin, Laura T., Rao, Deepak A., Wei, Kevin, Slowikowski, Kamil, McGeachy, Mandy J., Turner, Jason D., Meednu, Nida, Mizoguchi, Fumitaka, Gutierrez-Arcelus, Maria, Lieb, David J., Keegan, Joshua, Muskat, Kaylin, Hillman, Joshua, Rozo, Cristina, Ricker, Edd, Eisenhaure, Thomas M., Li, Shuqiang, Browne, Edward P., Chicoine, Adam, Sutherby, Danielle, Noma, Akiko, Nusbaum, Chad, Kelly, Stephen, Pernis, Alessandra B., Ivashkiv, Lionel B., Goodman, Susan M., Robinson, William H., Utz, Paul J., Lederer, James A., Gravallese, Ellen M., Boyce, Brendan F., Hacohen, Nir, Pitzalis, Costantino, Gregersen, Peter K., Firestein, Gary S., Raychaudhuri, Soumya, Moreland, Larry W., Holers, V. Michael, Bykerk, Vivian P., Filer, Andrew, Boyle, David L., Brenner, Michael B., Anolik, Jennifer H.

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Methods for high-dimensonal analysis of cells dissociated from cyropreserved synovial tissue by Donlin, Laura T, Rao, Deepak A, Wei, Kevin, Slowikowski, Kamil, McGeachy, Mandy J, Turner, Jason D, Meednu, Nida, Mizoguchi, Fumitaka, Gutierrez-Arcelus, Maria, Lieb, David J, Keegan, Joshua, Muskat, Kaylin, Hillman, Joshua, Rozo, Cristina, Ricker, Edd, Eisenhaure, Thomas M, Li, Shuqiang, Browne, Edward P, Chicoine, Adam, Sutherby, Danielle, Noma, Akiko, Nusbaum, Chad, Kelly, Stephen, Pernis, Alessandra B, Ivashkiv, Lionel B, Goodman, Susan M, Robinson, William H, Utz, Paul J, Lederer, James A, Gravallese, Ellen M, Boyce, Brendan F, Hacohen, Nir, Pitzalis, Costantino, Gregersen, Peter K, Firestein, Gary S, Raychaudhuri, Soumya, Moreland, Larry W, Holers, V Michael, Bykerk, Vivian P, Filer, Andrew, Boyle, David L, Brenner, Michael B, Anolik, Jennifer H

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Automated multi-scale computational pathotyping (AMSCP) of inflamed synovial tissue by Bell, Richard D., Brendel, Matthew, Konnaris, Maxwell A., Xiang, Justin, Otero, Miguel, Fontana, Mark A., Bai, Zilong, Albrecht, Jennifer, Apruzzese, William, Boyce, Brendan F., Boyle, David L., Brenner, Michael B., Bridges, S. Louis, Buckley, Christopher D., Buckner, Jane H., Bykerk, Vivian P., Dolan, James, Eisenhaure, Thomas M., Filer, Andrew, Firestein, Gary S., Fonseka, Chamith Y., Gravallese, Ellen M., Gregersen, Peter K., Guthridge, Joel M., Gutierrez-Arcelus, Maria, Hacohen, Nir, Holers, V. Michael, Hughes, Laura B., James, Eddie A., James, Judith A., Jonsson, A. Helena, Keegan, Josh, Kelly, Stephen, Lederer, James A., Lee, Yvonne C., Lieb, David J., Mandelin, Arthur M., McGeachy, Mandy J., McNamara, Michael A., Mears, Joseph R., Mizoguchi, Fumitaka, Moreland, Larry, Nguyen, Jennifer P., Noma, Akiko, Nusbaum, Chad, Perlman, Harris, Ritchlin, Christopher T., Robinson, William H., Rohani-Pichavant, Mina, Rozo, Cristina, Salomon-Escoto, Karen, Seifert, Jennifer, Seshadri, Anupamaa, Slowikowski, Kamil, Sutherby, Danielle, Tabechian, Darren, Turner, Jason D., Utz, Paul J., Watts, Gerald F. M., Wei, Kevin, Pitzalis, Costantino, Rao, Deepak A., Raychaudhuri, Soumya, Krenitsky, Daria M., Meednu, Nida, Rangel-Moreno, Javier, Scheel-Toellner, Dagmar, Carr, Hayley, Nayar, Saba, McMurray, Jack, DiCarlo, Edward, Anolik, Jennifer H., Donlin, Laura T., Orange, Dana E., Kenney, H. Mark, Schwarz, Edward M., Filer, Andrew, Ivashkiv, Lionel B., Wang, Fei

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1012 Deep peripheral blood immunophenotyping identifies a subgroup of lupus nephritis patients characterized by high type 1 interferon signaling, persistent activated immune cells... by Horisberger, Alice, Griffith, Alec, Arazi, Arnon, Keegan, Joshua, Howard, Kaitlyn, Sasaki, Takanori, Ghosh, Tusharkanti, Fava, Andrea, Beuschel, Rebecca, Inamo, Jun, Pulford, John, Murzin, Ekaterina, Hancock, Brandon, Preisinger, Katie, Gutierrez-Arcelus, Maria, Eisenhaure, Thomas M, Guthridge, Joel, Hoover, Paul J, Dall’Era, Maria, Wofsy, David, Kamen, Diane L, Kalunian, Kenneth C, Furie, Richard, Belmont, Michael, Izmirly, Peter, Clancy, Robert, Hildeman, David, Woodle, Steve, Apruzzese, William, McMahon, Maureen A, Grossman, Jennifer, Barnas, Jennifer L, Payan-Schober, Fernanda, Ishimori, Mariko, Weisman, Michael, Kretzler, Matthias, Berthier, Celine C, Hodgin, Jeffrey, Putterman, Chaim, Hacohen, Nir, Brenner, Michael B, Anolik, Jennifer H, Davidson, Anne, James, Judith A, Raychaudhuri, Soumya, Petri, Michelle A, Buyon, Jill P, Diamond, Betty, Zhang, Fan, Lederer, James A, Rao, Deepak A

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Extranuclear DNA accumulates in aged cells and contributes to senescence and inflammation by Lan, Yuk Yuen, Heather, James M., Eisenhaure, Thomas, Garris, Christopher Stuart, Lieb, David, Raychowdhury, Raktima, Hacohen, Nir

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Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection by Li, Bo, Clohisey, Sara M, Chia, Bing Shao, Wang, Bo, Cui, Ang, Eisenhaure, Thomas, Schweitzer, Lawrence D, Hoover, Paul, Parkinson, Nicholas J, Nachshon, Aharon, Smith, Nikki, Regan, Tim, Farr, David, Gutmann, Michael U, Bukhari, Syed Irfan, Law, Andrew, Sangesland, Maya, Gat-Viks, Irit, Digard, Paul, Vasudevan, Shobha, Lingwood, Daniel, Dockrell, David H, Doench, John G, Baillie, J Kenneth, Hacohen, Nir

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