SGK2, 14-3-3, and HUWE1 Cooperate to Control the Localization, Stability, and Function of the Oncoprotein PTOV1 by Pennington, Katie L, McEwan, Colten M, Woods, James, Muir, Colin M, Pramoda Sahankumari, A G, Eastmond, Riley, Balasooriya, Eranga R, Egbert, Christina M, Kaur, Sandeep, Heaton, Tyler, McCormack, Katherine K, Piccolo, Stephen R, Kurokawa, Manabu, Andersen, Joshua L

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TNK1 negatively regulates TBK1 at ubiquitin condensates by Lopez‐Palacios, Tania, Egbert, Christina M., Chan, Tsz‐Yin, Ashworth, Spencer, Vaughan, Alec, Andersen, Joshua

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A 14‐3‐3‐mediated mechanism of regulation for the ubiquitin‐sensing kinase TNK1 by Egbert, Christina M., Chan, Tsz‐Yin, Lopez‐Palacios, Tania, Ashworth, Spencer, McCormack, Katherine, Vaughan, Alec, Andersen, Joshua

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A mechanism of TNK1 activation by C‐terminal gene truncation in human lymphomas by Ashworth, Spencer W., Egbert, Christina M., Lopez‐Palacios, Tania, Chan, Tsz‐Yin, Vaughan, Alec, McCormack, Katherine, Andersen, Joshua

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SIRT5 IS A DRUGGABLE METABOLIC VULNERABILITY IN ACUTE MYELOID LEUKEMIA by Yan, Dongqing, Franzini, Anca, Pomicter, Anthony D, Halverson, Brayden J, Antelope, Orlando, Mason, Clinton C, Ahmann, Jonathan M, Senina, Anna V, Vellore, Nadeem A, Jones, Courtney L, Zabriskie, Matthew S, Than, Hein, Xiao, Michael J, van Scoyk, Alexandria, Patel, Ami B, Clair, Phillip M, Heaton, William L, Owen, Shawn C, Andersen, Joshua L, Egbert, Christina M, Reisz, Julie A, D'Alessandro, Angelo, Cox, James E, Gantz, Kevin C, Redwine, Hannah M, Iyer, Siddharth M, Khorashad, Jamshid S, Rajabi, Nima, Olsen, Christian A, O'Hare, Thomas, Deininger, Michael W

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TNK1 is a ubiquitin‐sensing kinase that can be targeted to block tumor growth by Andersen, Joshua L., Chan, Tsz‐Yin, Egbert, Christina M., Lopez‐Palacios, Tania, Maxson, Julia E., Tyner, Jeffrey W., Warner, Steven L.

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TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth by Chan, Tsz-Yin, Egbert, Christina M, Maxson, Julia E, Siddiqui, Adam, Larsen, Logan J, Kohler, Kristina, Balasooriya, Eranga Roshan, Pennington, Katie L, Tsang, Tsz-Ming, Frey, Madison, Soderblom, Erik J, Geng, Huimin, Müschen, Markus, Forostyan, Tetyana V, Free, Savannah, Mercenne, Gaelle, Banks, Courtney J, Valdoz, Jonard, Whatcott, Clifford J, Foulks, Jason M, Bearss, David J, O'Hare, Thomas, Huang, David C S, Christensen, Kenneth A, Moody, James, Warner, Steven L, Tyner, Jeffrey W, Andersen, Joshua L

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Abstract LB109: A critical role for SIRT5 in acute myeloid leukemia metabolism by Yan, Dongqing, Franzini, Anca, Pomicter, Anthony D., Halverson, Brayden J., Antelope, Orlando, Mason, Clinton C., Ahmann, Jonathan M., Senina, Anna V., Jones, Courtney L. L., Zabriskie, Matthew S., Than, Hein, Xiao, Michael J., van Scoyk, Alexandria, Patel, Ami B., Heaton, William L. L., Owen, Shawn C., Andersen, Joshua L., Egbert, Christina M., Reisz, Julie A., D'Alessandro, Angelo, Cox, James E., Gantz, Kevin C., Redwine, Hannah M., Iyer, Siddharth M., Khorashad, Jamshid S., Rajabi, Nima, Olsen, Christian A., O'Hare, Thomas, Deininger, Michael W.

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Abstract 3489: TNK1 is a ubiquitin sensing kinase that can be targeted in vivo to block tumor growth by Lopez-Palacios, Tania, Chan, Tsz-Yin, Egbert, Christina M., Ashworth, Spencer, Vaughan, Alec, Forostyan, Tanya V., Siddiqui, Adam, Foulks, Jason M., Moody, James, Maxson, Julia E., Tyner, Jeffrey W., Warner, Steven L., Andersen, Joshua Lyon

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Abstract 1469: 14-3-3 binding during G1 stabilizes and sequesters PTOV1 to the cytoplasm by Pennington, Katie L., McEwan, Colten M., Woods, James, Muir, Colin M., Sahankumari, A G Pramoda, Eastmond, Riley, Balasooriya, Eranga R., Egbert, Christina M., McCormack, Katherine K., Andersen, Joshua L.

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Trastuzumab deruxtecan in patients with metastatic non-small-cell lung cancer (DESTINY-Lung01): primary results of the HER2-overexpressing cohorts from a single-arm, phase 2 trial by Smit, Egbert F, Felip, Enriqueta, Uprety, Dipesh, Nagasaka, Misako, Nakagawa, Kazuhiko, Paz-Ares Rodríguez, Luis, Pacheco, Jose M, Li, Bob T, Planchard, David, Baik, Christina, Goto, Yasushi, Murakami, Haruyasu, Saltos, Andreas, Pereira, Kaline, Taguchi, Ayumi, Cheng, Yingkai, Yan, Qi, Feng, Wenqin, Tsuchihashi, Zenta, Jänne, Pasi A

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Transmission of Cryptosporidium Species Among Human and Animal Local Contact Networks in Sub-Saharan Africa: A Multicountry Study by Krumkamp, Ralf, Aldrich, Cassandra, Maiga-Ascofare, Oumou, Mbwana, Joyce, Rakotozandrindrainy, Njari, Borrmann, Steffen, Caccio, Simone M, Rakotozandrindrainy, Raphael, Adegnika, Ayola Akim, Lusingu, John P A, Amuasi, John, May, Jürgen, Eibach, Daniel

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Association of healthcare worker behaviors with coronavirus disease 2019 (COVID-19) risk during four pandemic periods and characteristics associated with high-risk behaviors by Egbert, Emily R, Xiao, Shaoming, Prochaska, Erica, Ali, S Omar, Colantuoni, Elizabeth, Gadala, Avi, Koontz, Danielle, Zhong, Diana, Schumacher, Christina M, Sick-Samuels, Anna C, Debes, Amanda K, Milstone, Aaron M

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Systematic outperformance of 112 dermatologists in multiclass skin cancer image classification by convolutional neural networks by Weichenthal, Michael, Utikal, Jochen S., Hekler, Achim, Berking, Carola, Hauschild, Axel, Enk, Alexander H., Haferkamp, Sebastian, Klode, Joachim, Schadendorf, Dirk, Jansen, Philipp, Holland-Letz, Tim, Schilling, Bastian, von Kalle, Christof, Fröhling, Stefan, Gaiser, Maria R., Hartmann, Daniela, Gesierich, Anja, Kähler, Katharina C., Wehkamp, Ulrike, Karoglan, Ante, Bär, Claudia, Brinker, Titus J., Peitsch, Wiebke K., Hoffmann, Friederike, Becker, Jürgen C., Drusio, Christina, Jansen, Philipp, Klode, Joachim, Lodde, Georg, Sammet, Stefanie, Schadendorf, Dirk, Sondermann, Wiebke, Ugurel, Selma, Enk, Alexander, Salzmann, Martin, Schäfer, Sarah, Schäkel, Knut, Winkler, Julia, Wölbing, Priscilla, Asper, Hiba, Brown, Victoria, Burba, Bianca, Deffaa, Sophia, Dietrich, Cecilia, Dietrich, Matthias, Egberts, Friederike, Harde, Viola, Jost, Marion, Kaeding, Merit, Kosova, Katharina, Lischner, Stephan, Messinger, Anna Laetitia, Metzner, Malte, Motamedi, Rogina, Rosenthal, Ann-Christine, Seidl, Ulrich, Stemmermann, Jana, Torz, Kaspar, Velez, Juliana Giraldo, Haiduk, Jennifer, Alter, Mareike, Bär, Claudia, Bergenthal, Paul, Gerlach, Anne, Holtorf, Christian, Karoglan, Ante, Kindermann, Sophie, Kraas, Luise, Felcht, Moritz, Gaiser, Maria R., Kurzen, Hjalmar, Leibing, Thomas, Müller, Verena, Reinhard, Raphael R., Utikal, Jochen, Winter, Franziska, Berking, Carola, Eicher, Laurie, Hartmann, Daniela, Heppt, Markus, Kilian, Katharina, Krammer, Sebastian, Lill, Diana, Niesert, Anne-Charlotte, Sattler, Elke, Senner, Sonja, Wallmichrath, Jens, Wolff, Hans, Giner, Tina, Glutsch, Valerie, Kerstan, Andreas, Presser, Dagmar, Schrüfer, Philipp, Schummer, Patrick, Stolze, Ina, Weber, Judith, Drexler, Konstantin, Haferkamp, Sebastian, Mickler, Marion, Stauner, Camila Toledo

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Repaglinide versus insulin for newly diagnosed diabetes in patients with cystic fibrosis: a multicentre, open-label, randomised trial by Ballmann, Manfred, Hubert, Dominique, Assael, Baroukh M, Staab, Doris, Hebestreit, Alexandra, Naehrlich, Lutz, Nickolay, Tanja, Prinz, Nicole, Holl, Reinhard W, Staden, Ute, Claßen, Martin, Schuster, Antje, Mellies, Uwe, Posselt, Hans-Georg, Wiebel, Matthias, Rietschel, Ernst, Stern, Martin, Teschler, Helmut, Smaczny, Christina, Köhnlein, Thomas, Wienhausen-Wilke, Vera, Claaß, Andreas, Biedermann, Thomas, Dockter, Gerd, Köster, Holger, Hebestreit, Helge, Ballke, Ernst-Hinrich, Heuer, Hans-Eberhard, Kamin, Wolfgang, Küster, Peter, Szczepanski, Rüdiger, Keller, Klaus-Michael, Generlich, Horst, Bresser, Hans-Georg, Kopp, Matthias, Herting, Egbert, Feickert, Hans-Joachim, Hautz, Jürgen, Schilling, Birgit, Meyer, Egbert, Mall, Marcus A, Wiebicke, Wolfram, Tegtmeyer, Friedrich-Karl, Honer, Marguerite, Mosnier-Pudar, Helen, Lenoir, Gérard, Robert, Jean-Jacques, Kessler, Laurence, Weiss, Laurence, Nove-Josserand, Raphaële, Vantyghem, Marie-Christine, Munck, Anne, Wizla, Nathalie, Leroy, Sylvie, Loeuille, Guy-André, Serreau, Raphaël, Aissat, Fawzia, Thalhammer, Gabriela H, Huttegger, Isidor, Eichler, Irmgard, Götz, Manfred

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Prevalence of von Hippel-Lindau gene mutations in sporadic renal cell carcinoma: results from The Netherlands cohort study by van Houwelingen, Kjeld P, van Dijk, Boukje A C, Hulsbergen-van de Kaa, Christina A, Schouten, Leo J, Gorissen, Hanneke J M, Schalken, Jack A, van den Brandt, Piet A, Oosterwijk, Egbert

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Epigenetic Regulation of Tissue-Type Plasminogen Activator in Human Brain Tissue and Brain-Derived Cells by Olsson, Martina, Hultman, Karin, Dunoyer-Geindre, Sylvie, Curtis, Maurice A., Faull, Richard L. M., Kruithof, Egbert K. O., Jern, Christina

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Abstract 2307: Elucidation of a unique regulatory mechanism for TNK1 provides potential therapeutic targeting opportunities in cancer by Chan, Tsz-Yin, Egbert, Christina, Larsen, Logan, Tsang, Jeremy, Maxson, Julia, Roshan, Eranga, Whatcott, Clifford J., Wontak, Kim, Mercenne, Gaelle, Free, Savannah, Siddiqui, Adam, Forostyan, Tetyana, Tyagi, Ethika, Christensen, Kenneth A., Bearss, David J., Moody, James, Tyner, Jeffrey, Foulks, Jason M., Warner, Steven L., Andersen, Joshua Lyon

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Genetic and Epigenetic Alterations in the von Hippel-Lindau Gene: the Influence on Renal Cancer Prognosis by SMITS, Kim M, SCHOUTEN, Leo J, VAN DIJK, Boukje A. C, HULSBERGEN-VAN DE KAA, Christina A, WOUTERS, Kim A. D, OOSTERWIJK, Egbert, VAN ENGELAND, Manon, VAN DEN BRANDT, Piet A

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PCM4EU and PRIME-ROSE: Collaboration for implementation of precision cancer medicine in Europe by Taskén, Kjetil, F Haj Mohammad, Soemeya, Fagereng, Gro Live, Sørum Falk, Ragnhild, Helland, Åslaug, Barjesteh van Waalwijk van Doorn-Khosrovani, Sahar, Steen Carlsson, Katarina, Ryll, Bettina, Jalkanen, Katriina, Edsjö, Anders, Russnes, Hege G, Lassen, Ulrik, Hallersjö Hult, Ebba, Lugowska, Iwona, Blay, Jean-Yves, Verlingue, Loic, Abel, Edvard, Lowery, Maeve A, Krebs, Matthew G, Staal Rohrberg, Kristoffer, Ojamaa, Kristiina, Oliveira, Julio, Verheul, Henk M W, Voest, Emile E, Gelderblom, Hans

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