Capecitabine compared with observation in resected biliary tract cancer (BILCAP): a randomised, controlled, multicentre, phase 3 study

by Primrose, John N, Fox, Richard P, Palmer, Daniel H, Malik, Hassan Z, Prasad, Raj, Mirza, Darius, Anthony, Alan, Corrie, Pippa, Falk, Stephen, Finch-Jones, Meg, Wasan, Harpreet, Ross, Paul, Wall, Lucy, Wadsley, Jonathan, Evans, Jeff T R, Stocken, Deborah, Praseedom, Raaj, Ma, Yuk Ting, Davidson, Brian, Neoptolemos, John P, Iveson, Tim, Raftery, James, Zhu, Shihua, Cunningham, David, Garden, O James, Stubbs, Clive, Valle, Juan W, Bridgewater, John, Primrose, JN, Fox, RP, Morement, H, Chan, O, Rees, C, Ma, YT, Hickish, T, Falk, S, Finch-Jones, M, Pope, I, Corrie, P, Crosby, T, Sothi, S, Sharkland, K, Adamson, D, Wall, L, Evans, J, Dent, J, Hombaiah, U, Iwuji, C, Anthoney, A, Bridgewater, J, Cunningham, D, Gillmore, R, Ross, P, Slater, S, Wasan, H, Waters, J, Valle, JW, Palmer, D, Malik, H, Neoptolemos, J, Faluyi, O, Sumpter, K, Dernedde, U, Maduhusudan, S, Cogill, G, Archer, C, Iveson, T, Wadsley, J, Darby, S, Peterson, M, Mukhtar, AA, Thorpe, JG, Bateman, A, Tsang, D, Cummins, S, Nolan, L, Beaumont, E, Prasad, R, Mirza, D, Stocken, D, Praseedom, R, Davidson, B, Raftery, J, Zhu, S, Garden, J, Stubbs, C, Coxon, F
Published in The lancet oncology

Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study

by Ström, Peter, Kartasalo, Kimmo, Olsson, Henrik, Solorzano, Leslie, Delahunt, Brett, Berney, Daniel M, Bostwick, David G, Evans, Andrew J, Grignon, David J, Humphrey, Peter A, Iczkowski, Kenneth A, Kench, James G, Kristiansen, Glen, van der Kwast, Theodorus H, Leite, Katia R M, McKenney, Jesse K, Oxley, Jon, Pan, Chin-Chen, Samaratunga, Hemamali, Srigley, John R, Takahashi, Hiroyuki, Tsuzuki, Toyonori, Varma, Murali, Zhou, Ming, Lindberg, Johan, Lindskog, Cecilia, Ruusuvuori, Pekka, Wählby, Carolina, Grönberg, Henrik, Rantalainen, Mattias, Egevad, Lars, Eklund, Martin
Published in The lancet oncology

CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma

by Steele, Colin W., Karim, Saadia A., Leach, Joshua D.G., Bailey, Peter, Upstill-Goddard, Rosanna, Rishi, Loveena, Foth, Mona, Bryson, Sheila, McDaid, Karen, Wilson, Zena, Eberlein, Catherine, Candido, Juliana B., Clarke, Mairi, Nixon, Colin, Connelly, John, Jamieson, Nigel, Carter, C. Ross, Balkwill, Frances, Chang, David K., Evans, T.R. Jeffry, Strathdee, Douglas, Biankin, Andrew V., Nibbs, Robert J.B., Barry, Simon T., Sansom, Owen J., Morton, Jennifer P.
Published in Cancer cell

Phase 1 study of the ATR inhibitor berzosertib (formerly M6620, VX-970) combined with gemcitabine ± cisplatin in patients with advanced solid tumours

by Middleton, Mark R, Dean, Emma, Evans, Thomas R J, Shapiro, Geoffrey I, Pollard, John, Hendriks, Bart S, Falk, Martin, Diaz-Padilla, Ivan, Plummer, Ruth
Published in British journal of cancer

An early analysis of the cost-effectiveness of a diagnostic classifier for risk stratification of haematuria patients (DCRSHP) compared to flexible cystoscopy in the diagnosis of b...

by Sutton, Andrew J, Lamont, John V, Evans, R Mark, Williamson, Kate, O'Rourke, Declan, Duggan, Brian, Sagoo, Gurdeep S, Reid, Cherith N, Ruddock, Mark W
Published in PloS one

Inhibition of the Nuclear Export Receptor XPO1 as a Therapeutic Target for Platinum-Resistant Ovarian Cancer

by Chen, Ying, Camacho, Sandra Catalina, Silvers, Thomas R, Razak, Albiruni R A, Gabrail, Nashat Y, Gerecitano, John F, Kalir, Eva, Pereira, Elena, Evans, Brad R, Ramus, Susan J, Huang, Fei, Priedigkeit, Nolan, Rodriguez, Estefania, Donovan, Michael, Khan, Faisal, Kalir, Tamara, Sebra, Robert, Uzilov, Andrew, Chen, Rong, Sinha, Rileen, Halpert, Richard, Billaud, Jean-Noel, Shacham, Sharon, McCauley, Dilara, Landesman, Yosef, Rashal, Tami, Kauffman, Michael, Mirza, Mansoor R, Mau-Sørensen, Morten, Dottino, Peter, Martignetti, John A
Published in Clinical cancer research

Association between the cervicovaginal microbiome, BRCA1 mutation status, and risk of ovarian cancer: a case-control study

by Nené, Nuno R, PhD, Reisel, Daniel, PhD, Leimbach, Andreas, PhD, Franchi, Dorella, MD, Jones, Allison, BSc, Evans, Iona, PhD, Knapp, Susanne, PhD, Ryan, Andy, PhD, Ghazali, Shohreh, MSc, Timms, John F, DPhil, Paprotka, Tobias, PhD, Bjørge, Line, Prof, Zikan, Michal, Prof, Cibula, David, Prof, Colombo, Nicoletta, Prof, Widschwendter, Martin, Prof
Published in The lancet oncology

The Long Non-Coding RNA PCAT-1 Promotes Prostate Cancer Cell Proliferation through cMyc

by Prensner, John R, Chen, Wei, Han, Sumin, Iyer, Matthew K, Cao, Qi, Kothari, Vishal, Evans, Joseph R, Knudsen, Karen E, Paulsen, Michelle T, Ljungman, Mats, Lawrence, Theodore S, Chinnaiyan, Arul M, Feng, Felix Y
Published in Neoplasia (New York, N.Y.)

Participant selection for lung cancer screening by risk modelling (the Pan-Canadian Early Detection of Lung Cancer [PanCan] study): a single-arm, prospective study

by Tammemagi, Martin C, Schmidt, Heidi, Martel, Simon, McWilliams, Annette, Goffin, John R, Johnston, Michael R, Nicholas, Garth, Tremblay, Alain, Bhatia, Rick, Liu, Geoffrey, Soghrati, Kam, Yasufuku, Kazuhiro, Hwang, David M, Laberge, Francis, Gingras, Michel, Pasian, Sergio, Couture, Christian, Mayo, John R, Nasute Fauerbach, Paola V, Atkar-Khattra, Sukhinder, Peacock, Stuart J, Cressman, Sonya, Ionescu, Diana, English, John C, Finley, Richard J, Yee, John, Puksa, Serge, Stewart, Lori, Tsai, Scott, Haider, Ehsan, Boylan, Colm, Cutz, Jean-Claude, Manos, Daria, Xu, Zhaolin, Goss, Glenwood D, Seely, Jean M, Amjadi, Kayvan, Sekhon, Harmanjatinder S, Burrowes, Paul, MacEachern, Paul, Urbanski, Stefan, Sin, Don D, Tan, Wan C, Leighl, Natasha B, Shepherd, Frances A, Evans, William K, Tsao, Ming-Sound, Lam, Stephen
Published in The lancet oncology

Long-term outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer: meta-analysis of individual patient data from ten randomised trials

by Asselain, Bernard, Barlow, William, Bergh, Jonas, Bergsten-Nordström, Elizabeth, Bliss, Judith, Boccardo, Francesco, Boddington, Clare, Bogaerts, Jan, Bradley, Rosie, Brain, Etienne, Braybrooke, Jeremy, Broet, Philippe, Bryant, John, Burrett, Julie, Cameron, David, Clarke, Mike, Coates, Alan, Coleman, Robert, Coombes, Raoul Charles, Correa, Candace, Costantino, Joe, Cuzick, Jack, Davidson, Nancy, Davies, Christina, Davies, Lucy, Di Leo, Angelo, Dodwell, David, Dowsett, Mitch, Evans, Vaughan, Ewertz, Marianne, Fisher, Bernard, Forbes, John, Ford, Leslie, Gazet, Jean-Claude, Gelber, Richard, Gettins, Lucy, Gianni, Luca, Gnant, Michael, Godwin, Jon, Goldhirsch, Aron, Goodwin, Pamela, Gray, Richard, Hill, Catherine, Ingle, James, Jagsi, Reshma, Jakesz, Raimund, James, Sam, Janni, Wolfgang, Liu, Hui, Liu, Zulian, Lohrisch, Caroline, Loibl, Sibylle, Mamounas, Eleftherios, Mannu, Gurdeep, Martín, Miguel, Mathoulin, Simone, Mauriac, Louis, McGale, Paul, Morris, Philip, Mukai, Hirofumi, Norton, Larry, Ohashi, Yasuo, Olivotto, Ivo, Paik, Soon, Peto, Richard, Piccart, Martine, Pierce, Lori, Poortmans, Philip, Powles, Trevor, Pritchard, Kathy, Ragaz, Joseph, Raina, Vinod, Ravdin, Peter, Read, Simon, Regan, Meredith, Robertson, John, Rutgers, Emiel, Scholl, Suzy, Slamon, Dennis, Sölkner, Lidija, Steinberg, Seth, Sutcliffe, Rosemary, Swain, Sandra, Taylor, Carolyn, Tutt, Andrew, Valagussa, Pinuccia, van de Velde, Cornelis, van der Hage, Jos, Viale, Giuseppe, von Minckwitz, Gunter, Wang, Yaochen, Wang, Zhe, Wang, Xiang, Whelan, Tim, Wilcken, Nicholas, Winer, Eric, Wolmark, Norman, Wood, William, Zambetti, Milvia, Zujewski, Jo Anne
Published in The lancet oncology

A framework for the development of effective anti-metastatic agents

by Anderson, Robin L, Balasas, Theo, Callaghan, Juliana, Coombes, R Charles, Evans, Jeff, Hall, Jacqueline A, Kinrade, Sally, Jones, David, Jones, Paul S, Jones, Rob, Marshall, John F, Panico, Maria Beatrice, Shaw, Jacqui A, Steeg, Patricia S, Sullivan, Mark, Tong, Warwick, Westwell, Andrew D, Ritchie, James W A
Published in Nature reviews. Clinical oncology

The Cost-Effectiveness of High-Risk Lung Cancer Screening and Drivers of Program Efficiency

by Cressman, Sonya, Peacock, Stuart J., Tammemägi, Martin C., Evans, William K., Leighl, Natasha B., Goffin, John R., Tremblay, Alain, Liu, Geoffrey, Manos, Daria, MacEachern, Paul, Bhatia, Rick, Puksa, Serge, Nicholas, Garth, McWilliams, Annette, Mayo, John R., Yee, John, English, John C., Pataky, Reka, McPherson, Emily, Atkar-Khattra, Sukhinder, Johnston, Michael R., Schmidt, Heidi, Shepherd, Frances A., Soghrati, Kam, Amjadi, Kayvan, Burrowes, Paul, Couture, Christian, Sekhon, Harmanjatinder S., Yasufuku, Kazuhiro, Goss, Glenwood, Ionescu, Diana N., Hwang, David M., Martel, Simon, Sin, Don D., Tan, Wan C., Urbanski, Stefan, Xu, Zhaolin, Tsao, Ming-Sound, Lam, Stephen
Published in Journal of thoracic oncology

Tamoxifen for prevention of breast cancer: extended long-term follow-up of the IBIS-I breast cancer prevention trial

by Cuzick, Jack, Prof, Sestak, Ivana, PhD, Cawthorn, Simon, MD, Hamed, Hisham, MD, Holli, Kaija, Prof, Howell, Anthony, Prof, Forbes, John F, Prof
Published in The lancet oncology

Clinical utility of sequential minimal residual disease measurements in the context of risk-based therapy in childhood acute lymphoblastic leukaemia: a prospective study

by Pui, Ching-Hon, Prof, Pei, Deqing, MS, Coustan-Smith, Elaine, MS, Jeha, Sima, Prof, Cheng, Cheng, Prof, Bowman, W Paul, MD, Sandlund, John T, Prof, Ribeiro, Raul C, Prof, Rubnitz, Jeffrey E, Prof, Inaba, Hiroto, MD PhD, Bhojwani, Deepa, MD, Gruber, Tanja A, MD PhD, Leung, Wing H, Prof, Downing, James R, Prof, Evans, William E, Prof, Relling, Mary V, Prof, Campana, Dario, Prof
Published in The lancet oncology

Effect of Laparoscopic-Assisted Resection vs Open Resection on Pathological Outcomes in Rectal Cancer: The ALaCaRT Randomized Clinical Trial

by Stevenson, Andrew R. L, Solomon, Michael J, Lumley, John W, Hewett, Peter, Clouston, Andrew D, Gebski, Val J, Davies, Lucy, Wilson, Kate, Hague, Wendy, Simes, John
Published in JAMA : the journal of the American Medical Association

Biennial lung cancer screening in Canada with smoking cessation—outcomes and cost-effectiveness

by Goffin, John R., MD, FRCPC, Flanagan, William M., BM, Miller, Anthony B., MD, FRCPC, Fitzgerald, Natalie R., MA, Memon, Saima, MBBS, MPH, Wolfson, Michael C., PhD, Evans, William K., MD, FRCPC
Published in Lung cancer (Amsterdam, Netherlands)

Disease course of neurofibromatosis type 2: a 30-year follow-up study of 353 patients seen at a single institution

by Forde, Claire, King, Andrew T, Rutherford, Scott A, Hammerbeck-Ward, Charlotte, Lloyd, Simon K, Freeman, Simon R, Pathmanaban, Omar N, Stapleton, Emma, Thomas, Owen M, Laitt, Roger D, Stivaros, Stavros, Kilday, John-Paul, Vassallo, Grace, McBain, Catherine, Kerrigan, Simon, Smith, Miriam J, McCabe, Martin G, Harkness, Elaine F, Evans, D Gareth
Published in Neuro-oncology (Charlottesville, Va.)

Evaluation of pediatric glioma outcomes using intraoperative MRI: a multicenter cohort study

by Karsy, Michael, Akbari, S. Hassan, Limbrick, David, Leuthardt, Eric C., Evans, John, Smyth, Matthew D., Strahle, Jennifer, Leonard, Jeffrey, Cheshier, Samuel, Brockmeyer, Douglas L., Bollo, Robert J., Kestle, John R., Honeycutt, John, Donahue, David J., Roberts, Richard A., Hansen, Daniel R., Riva-Cambrin, Jay, Sutherland, Garnette, Gallagher, Clair, Hader, Walter, Starreveld, Yves, Hamilton, Mark, Duhaime, Ann-Christine, Jensen, Randy L., Chicoine, Michael R.
Published in Journal of neuro-oncology

Landscape of Acquired Resistance to Osimertinib in EGFR -Mutant NSCLC and Clinical Validation of Combined EGFR and RET Inhibition with Osimertinib and BLU-667 for Acquired RET Fusi...

by Piotrowska, Zofia, Isozaki, Hideko, Lennerz, Jochen K, Gainor, Justin F, Lennes, Inga T, Zhu, Viola W, Marcoux, Nicolas, Banwait, Mandeep K, Digumarthy, Subba R, Su, Wenjia, Yoda, Satoshi, Riley, Amanda K, Nangia, Varuna, Lin, Jessica J, Nagy, Rebecca J, Lanman, Richard B, Dias-Santagata, Dora, Mino-Kenudson, Mari, Iafrate, A John, Heist, Rebecca S, Shaw, Alice T, Evans, Erica K, Clifford, Corinne, Ou, Sai-Hong I, Wolf, Beni, Hata, Aaron N, Sequist, Lecia V
Published in Cancer discovery

Adjuvant Chemotherapy With Fluorouracil Plus Folinic Acid vs Gemcitabine Following Pancreatic Cancer Resection: A Randomized Controlled Trial

by Neoptolemos, John P, Stocken, Deborah D, Bassi, Claudio, Ghaneh, Paula, Cunningham, David, Goldstein, David, Padbury, Robert, Moore, Malcolm J, Gallinger, Steven, Mariette, Christophe, Wente, Moritz N, Izbicki, Jakob R, Friess, Helmut, Lerch, Markus M, Dervenis, Christos, Oláh, Attila, Butturini, Giovanni, Doi, Ryuichiro, Lind, Pehr A, Smith, David, Valle, Juan W, Palmer, Daniel H, Buckels, John A, Thompson, Joyce, McKay, Colin J, Rawcliffe, Charlotte L, Büchler, Markus W, European Study Group for Pancreatic Cancer, for the
Published in JAMA : the journal of the American Medical Association