BRCA1 Recruitment to Transcriptional Pause Sites Is Required for R-Loop-Driven DNA Damage Repair by Hatchi, Elodie, Skourti-Stathaki, Konstantina, Ventz, Steffen, Pinello, Luca, Yen, Angela, Kamieniarz-Gdula, Kinga, Dimitrov, Stoil, Pathania, Shailja, McKinney, Kristine M., Eaton, Matthew L., Kellis, Manolis, Hill, Sarah J., Parmigiani, Giovanni, Proudfoot, Nicholas J., Livingston, David M.

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Conserved nucleosome positioning defines replication origins by Eaton, Matthew L, Galani, Kyriaki, Kang, Sukhyun, Bell, Stephen P, MacAlpine, David M

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Chromatin signatures of the Drosophila replication program by Eaton, Matthew L, Prinz, Joseph A, MacAlpine, Heather K, Tretyakov, George, Kharchenko, Peter V, MacAlpine, David M

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Noncoding Transcription Is a Driving Force for Nucleosome Instability in spt16 Mutant Cells by Feng, Jianxun, Gan, Haiyun, Eaton, Matthew L., Zhou, Hui, Li, Shuqi, Belsky, Jason A., MacAlpine, David M., Zhang, Zhiguo, Li, Qing

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The conserved bromo-adjacent homology domain of yeast Orc1 functions in the selection of DNA replication origins within chromatin by Müller, Philipp, Park, Sookhee, Shor, Erika, Huebert, Dana J, Warren, Christopher L, Ansari, Aseem Z, Weinreich, Michael, Eaton, Matthew L, MacAlpine, David M, Fox, Catherine A

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Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist by McKeown, Michael R, Corces, M Ryan, Eaton, Matthew L, Fiore, Chris, Lee, Emily, Lopez, Jeremy T, Chen, Mei Wei, Smith, Darren, Chan, Steven M, Koenig, Julie L, Austgen, Kathryn, Guenther, Matthew G, Orlando, David A, Lovén, Jakob, Fritz, Christian C, Majeti, Ravindra

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A cis-regulatory map of the Drosophila genome by NEGRE, Nicolas, BROWN, Christopher D, ZIRONG LI, ISHII, Haruhiko, SPOKONY, Rebecca F, JIA CHEN, HWANG, Lindsay, CHAO CHENG, AUBURN, Richard P, DAVIS, Melissa B, DOMANUS, Marc, SHAH, Parantu K, LIJIA MA, MORRISON, Carolyn A, ZIEBA, Jennifer, SUCHY, Sarah, SENDEROWICZ, Lionel, VICTORSEN, Alec, BILD, Nicholas A, GRUNDSTAD, A. Jason, HANLEY, David, MACALPINE, David M, MANNERVIK, Mattias, AARON BRISTOW, Christopher, VENKEN, Koen, BELLEN, Hugo, WHITE, Robert, GERSTEIN, Mark, RUSSELL, Steven, GROSSMAN, Robert L, BING REN, POSAKONY, James W, KELLIS, Manolis, WHITE, Kevin P, MILLER, Steven W, WAGNER, Ulrich, KHERADPOUR, Pouya, EATON, Matthew L, LORIAUX, Paul, SEALFON, Rachel

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Multimodal Regulation of E2F1 Gene Expression by Progestins by Wade, Hilary E., Kobayashi, Sakiko, Eaton, Matthew L., Jansen, Michelle S., Lobenhofer, Edward K., Lupien, Mathieu, Geistlinger, Timothy R., Zhu, Wencheng, Nevins, Joseph R., Brown, Myles, Otteson, Deborah C., McDonnell, Donald P.

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Developmental control of gene copy number by repression of replication initiation and fork progression by Sher, Noa, Bell, George W, Li, Sharon, Nordman, Jared, Eng, Thomas, Eaton, Matthew L, Macalpine, David M, Orr-Weaver, Terry L

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WNT11 expression is induced by estrogen-related receptor alpha and beta-catenin and acts in an autocrine manner to increase cancer cell migration by Dwyer, Mary A, Joseph, James D, Wade, Hilary E, Eaton, Matthew L, Kunder, Rebecca S, Kazmin, Dmitri, Chang, Ching-yi, McDonnell, Donald P

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Alzheimer's loci: epigenetic associations and interaction with genetic factors by Chibnik, Lori B., Yu, Lei, Eaton, Matthew L., Srivastava, Gyan, Schneider, Julie A., Kellis, Manolis, Bennett, David A., De Jager, Philip L.

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Integrative analysis of 111 reference human epigenomes by Kundaje, Anshul, Meuleman, Wouter, Ernst, Jason, Bilenky, Misha, Yen, Angela, Heravi-Moussavi, Alireza, Kheradpour, Pouya, Zhang, Zhizhuo, Wang, Jianrong, Ziller, Michael J, Amin, Viren, Whitaker, John W, Schultz, Matthew D, Ward, Lucas D, Sarkar, Abhishek, Quon, Gerald, Sandstrom, Richard S, Eaton, Matthew L, Wu, Yi-Chieh, Pfenning, Andreas R, Wang, Xinchen, Claussnitzer, Melina, Liu, Yaping, Coarfa, Cristian, Harris, R Alan, Shoresh, Noam, Epstein, Charles B, Gjoneska, Elizabeta, Leung, Danny, Xie, Wei, Hawkins, R David, Lister, Ryan, Hong, Chibo, Gascard, Philippe, Mungall, Andrew J, Moore, Richard, Chuah, Eric, Tam, Angela, Canfield, Theresa K, Hansen, R Scott, Kaul, Rajinder, Sabo, Peter J, Bansal, Mukul S, Carles, Annaick, Dixon, Jesse R, Farh, Kai-How, Feizi, Soheil, Karlic, Rosa, Kim, Ah-Ram, Kulkarni, Ashwinikumar, Li, Daofeng, Lowdon, Rebecca, Elliott, GiNell, Mercer, Tim R, Neph, Shane J, Onuchic, Vitor, Polak, Paz, Rajagopal, Nisha, Ray, Pradipta, Sallari, Richard C, Siebenthall, Kyle T, Sinnott-Armstrong, Nicholas A, Stevens, Michael, Thurman, Robert E, Wu, Jie, Zhang, Bo, Zhou, Xin, Beaudet, Arthur E, Boyer, Laurie A, De Jager, Philip L, Farnham, Peggy J, Fisher, Susan J, Haussler, David, Jones, Steven J M, Li, Wei, Marra, Marco A, McManus, Michael T, Sunyaev, Shamil, Thomson, James A, Tlsty, Thea D, Tsai, Li-Huei, Wang, Wei, Waterland, Robert A, Zhang, Michael Q, Chadwick, Lisa H, Bernstein, Bradley E, Costello, Joseph F, Ecker, Joseph R, Hirst, Martin, Meissner, Alexander, Milosavljevic, Aleksandar, Ren, Bing, Stamatoyannopoulos, John A, Wang, Ting, Kellis, Manolis

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An integrated encyclopedia of DNA elements in the human genome by Kundaje, Anshul, Collins, Patrick J, Davis, Carrie A, Khatun, Jainab, Lajoie, Bryan R, Landt, Stephen G, Safi, Alexias, Altshuler, Robert C, Cheng, Chao, Greven, Melissa, Hoffman, Michael M, Lassmann, Timo, Thurman, Robert E, Wu, Weisheng, Xi, Hualin S, Zhuang, Jiali, Gunter, Chris, Dekker, Job, Elnitski, Laura, Giddings, Morgan C, Margulies, Elliott H, Stamatoyannopoulos, John A, Wold, Barbara, Kuiper, Heather C, Dobin, Alex, Tanzer, Andrea, Xue, Chenghai, Zaleski, Chris, Roder, Maik, Baer, Michael T, Bell, Kimberly, Gordon, Assaf, Howald, Cedric, Johnson, Rory, Kingswood, Colin, Li, Guoliang, Luo, Oscar J, Robyr, Daniel, Ruan, Xiaoan, Skancke, Jorgen, Suzuki, Ana Maria, Takahashi, Hazuki, Tilgner, Hagen, Wang, Huaien, Hayashizaki, Yoshihide, Hannon, Gregory J, Malladi, Venkat S, Dreszer, Timothy R, Showers, Kimberly A, London, Darin, Zhang, Zhancheng, Keefe, Damian, Zheng, Meizhen, Vielmetter, Jost, Jain, Preti, Pusey, Barbara, Meadows, Sarah K, Absher, Devin M, Pennachio, Len A, Abyzov, Alexej, Barrell, Daniel, Bignell, Alexandra, Diekhans, Mark, Ezkurdia, Iakes, Frankish, Adam, Hunt, Toby, Jungreis, Irwin, Loveland, Jane, Manthravadi, Deepa, Pei, Baikang, Snow, Catherine, Zhang, Zhengdong, Alexander, Roger P, Balasubramanian, Suganthi, Bettinger, Keith, Cayting, Philip, Habegger, Lukas, Lamarre-Vincent, Nathan, Lindahl-Allen, Marianne, Monahan, Hannah, Patacsil, Dorrelyn, Struhl, Kevin, Ma, Lijia, Inoue, Daigo, Kellner, Tanja, Kirchmaier, Stephan, Bates, Daniel L, Canfield, Theresa K, Boatman, Lisa, Neph, Shane J, Roach, Vaughn, Sanchez, Minerva E, Shafer, Anthony O, Vernot, Benjamin, Weaver, Molly A, Akey, Joshua M, Bender, Michael, Navas, Patrick, Hussami, Nadine, Schaub, Marc A

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Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE by Roy, Sushmita, Ernst, Jason, Kharchenko, Peter V, Kheradpour, Pouya, Negre, Nicolas, Eaton, Matthew L, Landolin, Jane M, Bristow, Christopher A, Ma, Lijia, Lin, Michael F, Washietl, Stefan, Arshinoff, Bradley I, Ay, Ferhat, Meyer, Patrick E, Robine, Nicolas, Washington, Nicole L, Di Stefano, Luisa, Berezikov, Eugene, Brown, Christopher D, Candeias, Rogerio, Carlson, Joseph W, Carr, Adrian, Jungreis, Irwin, Marbach, Daniel, Sealfon, Rachel, Tolstorukov, Michael Y, Will, Sebastian, Alekseyenko, Artyom A, Artieri, Carlo, Booth, Benjamin W, Brooks, Angela N, Dai, Qi, Davis, Carrie A, Duff, Michael O, Feng, Xin, Gorchakov, Andrey A, Gu, Tingting, Henikoff, Jorja G, Kapranov, Philipp, Li, Renhua, MacAlpine, Heather K, Malone, John, Minoda, Aki, Nordman, Jared, Okamura, Katsutomo, Perry, Marc, Powell, Sara K, Riddle, Nicole C, Sakai, Akiko, Samsonova, Anastasia, Sandler, Jeremy E, Schwartz, Yuri B, Sher, Noa, Spokony, Rebecca, Sturgill, David, van Baren, Marijke, Wan, Kenneth H, Yang, Li, Yu, Charles, Feingold, Elise, Good, Peter, Guyer, Mark, Lowdon, Rebecca, Ahmad, Kami, Andrews, Justen, Berger, Bonnie, Brenner, Steven E, Brent, Michael R, Cherbas, Lucy, Elgin, Sarah C.R, Gingeras, Thomas R, Grossman, Robert, Hoskins, Roger A, Kaufman, Thomas C, Kent, William, Kuroda, Mitzi I, Orr-Weaver, Terry, Perrimon, Norbert, Pirrotta, Vincenzo, Posakony, James W, Ren, Bing, Russell, Steven, Cherbas, Peter, Graveley, Brenton R, Lewis, Suzanna, Micklem, Gos, Oliver, Brian, Park, Peter J, Celniker, Susan E, Henikoff, Steven, Karpen, Gary H, Lai, Eric C, MacAlpine, David M, Stein, Lincoln D, White, Kevin P, Kellis, Manolis

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Abstract 3085: SY-1425 (tamibarotene), a selective RARα agonist, shows synergistic anti-tumor activity with hypomethylating agents in a biomarker selected subset of AML by McKeown, Michael R., Lee, Emily, Fiore, Chris, Eaton, Matthew L., Fritz, Christian C., Olson, Eric

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Clinical Pharmacodynamic Markers and Combinations with SY1425 (tamibarotene) in a Genomically-Defined Subset of Non-APL AML by McKeown, Michael R, Fiore, Christopher, Lee, Emily, Eaton, Matthew L, Fritz, Christian C.

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SY1425 (tamibarotene) Induces Profound Transcriptional Changes in AML Tumors with High Retinoic Acid Receptor Alpha by Fiore, Christopher, McKeown, Michael R, Lee, Emily, Eaton, Matthew L, Fritz, Christian C.

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Abstract 2644: SY-1425, a selective RARα agonist, induces high levels of CD38 expression in RARA-high AML tumors creating a susceptibility to anti-CD38 therapeutic antibody treatme... by Austgen, Kathryn, McKeown, Michael R., Smith, Darren, Lee, Emily, Fiore, Chris, Eaton, Matthew L., Fritz, Christian, Lodie, Tracey, Olson, Eric

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Abstract 1511: AML patient clustering by super-enhancers reveals an RARA associated transcription factor signaling partner by McKeown, Michael R., Eaton, Matthew L., Fiore, Chris, Lee, Emily, Austgen, Katie, Smith, Darren, Corces, M. Ryan, Majeti, Ravindra, Fritz, Christian C.

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Abstract PR05: SY-1425 (tamibarotene), a potent and selective RARα agonist, induces changes in the transcriptional regulatory circuit of AML cells leading to differentiation by Fiore, Christopher M., McKeown, Michael R., Lee, Emily, Eaton, Matthew L., Smith, Darren, Austgen, Kathryn, Chen, Mei Wei, Guenther, Matthew, Corces, M. Ryan, Majeti, Ravindra, Olson, Eric, Fritz, Christian C.

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