Effect of Out-of-Hospital Tranexamic Acid vs Placebo on 6-Month Functional Neurologic Outcomes in Patients With Moderate or Severe Traumatic Brain Injury

by Rowell, Susan E, Meier, Eric N, McKnight, Barbara, Kannas, Delores, May, Susanne, Sheehan, Kellie, Bulger, Eileen M, Idris, Ahamed H, Christenson, Jim, Morrison, Laurie J, Frascone, Ralph J, Bosarge, Patrick L, Colella, M. Riccardo, Johannigman, Jay, Cotton, Bryan A, Callum, Jeannie, McMullan, Jason, Dries, David J, Tibbs, Brian, Richmond, Neal J, Weisfeldt, Myron L, Tallon, John M, Garrett, John S, Zielinski, Martin D, Aufderheide, Tom P, Gandhi, Rajesh R, Schlamp, Rob, Robinson, Bryce R. H, Jui, Jonathan, Klein, Lauren, Rizoli, Sandro, Gamber, Mark, Fleming, Michael, Hwang, Jun, Vincent, Laura E, Williams, Carolyn, Hendrickson, Audrey, Simonson, Robert, Klotz, Patricia, Sopko, George, Witham, William, Ferrara, Michael, Schreiber, Martin A
Published in JAMA : the journal of the American Medical Association

Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma: The PROPPR Randomized Clinical Trial

by Holcomb, John B, Tilley, Barbara C, Baraniuk, Sarah, Fox, Erin E, Wade, Charles E, Podbielski, Jeanette M, del Junco, Deborah J, Brasel, Karen J, Bulger, Eileen M, Callcut, Rachael A, Cohen, Mitchell Jay, Cotton, Bryan A, Fabian, Timothy C, Inaba, Kenji, Kerby, Jeffrey D, Muskat, Peter, O’Keeffe, Terence, Rizoli, Sandro, Robinson, Bryce R. H, Scalea, Thomas M, Schreiber, Martin A, Stein, Deborah M, Weinberg, Jordan A, Callum, Jeannie L, Hess, John R, Matijevic, Nena, Miller, Christopher N, Pittet, Jean-Francois, Hoyt, David B, Pearson, Gail D, Leroux, Brian, van Belle, Gerald
Published in JAMA : the journal of the American Medical Association

Computed Tomographic Colonography (Virtual Colonoscopy): A Multicenter Comparison With Standard Colonoscopy for Detection of Colorectal Neoplasia

by Cotton, Peter B, Durkalski, Valerie L, Pineau, Benoit C, Palesch, Yuko Y, Mauldin, Patrick D, Hoffman, Brenda, Vining, David J, Small, William C, Affronti, John, Rex, Douglas, Kopecky, Kenyon K, Ackerman, Susan, Burdick, J. Steven, Brewington, Cecelia, Turner, Mary A, Zfass, Alvin, Wright, Andrew R, Iyer, Revathy B, Lynch, Patrick, Sivak, Michael V, Butler, Harold
Published in JAMA : the journal of the American Medical Association

A 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and Longevity

by Ravussin, Eric, Redman, Leanne M, Rochon, James, Das, Sai Krupa, Fontana, Luigi, Kraus, William E, Romashkan, Sergei, Williamson, Donald A, Meydani, Simin N, Villareal, Dennis T, Smith, Steven R, Stein, Richard I, Scott, Tammy M, Stewart, Tiffany M, Saltzman, Edward, Klein, Samuel, Bhapkar, Manju, Martin, Corby K, Gilhooly, Cheryl H, Holloszy, John O, Hadley, Evan C, Roberts, Susan B
Published in The journals of gerontology. Series A, Biological sciences and medical sciences

Trends in Care Practices, Morbidity, and Mortality of Extremely Preterm Neonates, 1993-2012

by Stoll, Barbara J, Hansen, Nellie I, Bell, Edward F, Walsh, Michele C, Carlo, Waldemar A, Shankaran, Seetha, Laptook, Abbot R, Sánchez, Pablo J, Van Meurs, Krisa P, Wyckoff, Myra, Das, Abhik, Hale, Ellen C, Ball, M. Bethany, Newman, Nancy S, Schibler, Kurt, Poindexter, Brenda B, Kennedy, Kathleen A, Cotten, C. Michael, Watterberg, Kristi L, D’Angio, Carl T, DeMauro, Sara B, Truog, William E, Devaskar, Uday, Higgins, Rosemary D
Published in JAMA : the journal of the American Medical Association

No evidence of HIV replication in children on antiretroviral therapy

by Van Zyl, Gert U, Katusiime, Mary Grace, Wiegand, Ann, McManus, William R, Bale, Michael J, Halvas, Elias K, Luke, Brian, Boltz, Valerie F, Spindler, Jonathan, Laughton, Barbara, Engelbrecht, Susan, Coffin, John M, Cotton, Mark F, Shao, Wei, Mellors, John W, Kearney, Mary F
Published in The Journal of clinical investigation

Clinical and economic evaluation of laparoscopic surgery compared with medical management for gastro-oesophageal reflux disease: 5-year follow-up of multicentre randomised trial (t...

by Grant, A M, Boachie, C, Cotton, S C, Faria, R, Bojke, L, Epstein, D M, Ramsay, C R, Corbacho, B, Sculpher, M, Krukowski, Z H, Heading, R C, Campbell, M K
Published in Health technology assessment (Winchester, England)

The Pharmacokinetics and Pharmacodynamics of Micafungin in Experimental Hematogenous Candida Meningoencephalitis: Implications for Echinocandin Therapy in Neonates

by Hope, William W., Mickiene, Diana, Petraitis, Vidmantas, Petraitiene, Ruta, Kelaher, Amy M., Hughes, Joanna E., Cotton, Margaret P., Bacher, John, Keirns, James J., Buell, Donald, Heresi, Gloria, Benjamin, Daniel K., Groll, Andreas H., Drusano, George L., Walsh, Thomas J.
Published in The Journal of infectious diseases

Varicella-Zoster Virus–Specific Immune Responses in Elderly Recipients of a Herpes Zoster Vaccine

by Levin, M. J., Oxman, M. N., J. H. Zhang, Johnson, G. R., Stanley, H., Hayward, A. R., Caulfield, M. J., Irwin, M. R., Smith, J. G., Clair, J., Chan, I. S. F., Williams, H., Harbecke, R., Marchese, R., Straus, S. E., Gershon, A., Weinberg, A.
Published in The Journal of infectious diseases

Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and pharmacological and psychosocial management

by Bushby, Katharine, MD, Finkel, Richard, MD, Birnkrant, David J, MD, Case, Laura E, DPT, Clemens, Paula R, MD, Cripe, Linda, MD, Kaul, Ajay, MD, Kinnett, Kathi, MSN, McDonald, Craig, MD, Pandya, Shree, PT, Poysky, James, PhD, Shapiro, Frederic, MD, Tomezsko, Jean, PhD, Constantin, Carolyn, PhD
Published in Lancet neurology

Deep brain stimulation plus best medical therapy versus best medical therapy alone for advanced Parkinson's disease (PD SURG trial): a randomised, open-label trial

by Williams, Adrian, Prof, Gill, Steven, Prof, Varma, Thelekat, FRCS[Ed], Jenkinson, Crispin, Prof, Quinn, Niall, Prof, Mitchell, Rosalind, FRCS, Scott, Richard, PhD, Ives, Natalie, MSc, Rick, Caroline, PhD, Daniels, Jane, MSc, Patel, Smitaa, MSc, Wheatley, Keith, Prof
Published in Lancet neurology

HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma

by Zein, Joe, Gaston, Benjamin, Bazeley, Peter, DeBoer, Mark D., Igo, Robert P., Bleecker, Eugene R., Meyers, Deborah, Comhair, Suzy, Marozkina, Nadzeya V., Cotton, Calvin, Patel, Mona, Alyamani, Mohammad, Xu, Weiling, Busse, William W., Calhoun, William J., Ortega, Victor, Hawkins, Gregory A., Castro, Mario, Chung, Kian Fan, Fahy, John V., Fitzpatrick, Anne M., Israel, Elliot, Jarjour, Nizar N., Levy, Bruce, Mauger, David T., Moore, Wendy C., Noel, Patricia, Peters, Stephen P., Teague, W. Gerald, Wenzel, Sally E., Erzurum, Serpil C., Sharifi, Nima
Published in Proceedings of the National Academy of Sciences - PNAS

Pragmatic Randomized Optimal Platelet and Plasma Ratios (PROPPR) Trial: Design, rationale and implementation

by Baraniuk, Sarah, Tilley, Barbara C, del Junco, Deborah J, Fox, Erin E, van Belle, Gerald, Wade, Charles E, Podbielski, Jeanette M, Beeler, Angela M, Hess, John R, Bulger, Eileen M, Schreiber, Martin A, Inaba, Kenji, Fabian, Timothy C, Kerby, Jeffrey D, Cohen, Mitchell Jay, Miller, Christopher N, Rizoli, Sandro, Scalea, Thomas M, O’Keeffe, Terence, Brasel, Karen J, Cotton, Bryan A, Muskat, Peter, Holcomb, John B
Published in Injury

Empirical Therapy for Neonatal Candidemia in Very Low Birth Weight Infants

by Benjamin, Daniel K., Jr, DeLong, Elizabeth R, Steinbach, William J, Cotton, Charles M, Walsh, Thomas J, Clark, Reese H
Published in Pediatrics (Evanston)

Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI)

by Siddiqi, Nishat, Neil, Christopher, Bruce, Margaret, MacLennan, Graeme, Cotton, Seonaidh, Papadopoulou, Sofia, Feelisch, Martin, Bunce, Nicholas, Lim, Pitt O, Hildick-Smith, David, Horowitz, John, Madhani, Melanie, Boon, Nicholas, Dawson, Dana, Kaski, Juan Carlos, Frenneaux, Michael
Published in European heart journal

Older Blood Is Associated With Increased Mortality and Adverse Events in Massively Transfused Trauma Patients: Secondary Analysis of the PROPPR Trial

by Jones, Allison R., Patel, Rakesh P., Marques, Marisa B., Donnelly, John P., Hess, John R., Wang, Henry E., Holcomb, John B., del Junco, Deborah J., Matijevic, Nena, Podbielski, Jeanette, Beeler, Angela M., Tilley, Barbara C., Baraniuk, Sarah, Zhu, Hongjian, Nixon, Joshua, Seay, Roann, Gonzalez, Michael O., Baer, Lisa, Wang, Yao-Wei W., Hula, Brittany S., Espino, Elena, Arora-Nutall, Kisha D., Sharma, Rishika, Cardenas, Jessica C., Rahbar, Elaheh, Burnett, Tyrone, Clark, David, May, Susanne, Leroux, Brian, Hoyt, David, Sheehan, Kellie, Arkin, Adam P., Hess, John R., Welch, Timothy, Pivalizza, Evan G., Gumbert, Sam D., Bai, Yu, Noland, Amy, Bulger, Eileen M., Klotz, Patricia, Warner, Keir J., Wilson, Angela, Boman, David, White, Nathan, Grabinsky, Andreas, Cohen, Mitchell J., Callcut, Rachael A., Nelson, Mary, Redick, Brittney, Conroy, Amanda, Fiebig, Eberhard, Mallari, Eireen, Muskat, Peter, Robinson, Bryce R.H., Branson, Richard D., Gomaa, Dina, Rodriguez, Carolina, Inaba, Kenji, Zhu, Jay G., Wong, Monica D., Henderson, Sean O., Nelson, Janice M., Matsushita, Cheryl Y., Scalea, Thomas M., Shaffer, Cynthia K., Herrera, Anthony V., Kallam, Seeta, Fontaine, Magali J., Cooke, Rhonda K., Fabian, Timothy C., Weinberg, Jordan A., Croce, Martin A., Wilson, Suzanne, Waddle-Smith, Lynda, Flax, Sherri, Brasel, Karen J., Walsh, Pamela, Nelson, Allia, Rokowski, Laurel L., Redford, Daniel T., Novak, Deborah J., Knoll, Susan, Kerby, Jeffrey D., Pittet, Jean-Francois, Bosarge, Patrick L., Williams, Carolyn R., Stephens, Shannon W., Wang, Henry E., Marques, Marisa B., Schreiber, Martin A., Watters, Jennifer M., Groat, Tahnee, Newgard, Craig, Miller, Beth, Rizoli, Sandro, Nascimento, Barto, Sobrian-Couroux, Skeeta, Reis, Marciano, Belo, Susan E., Merkley, Lisa
Published in Annals of emergency medicine

Safety of Zoster Vaccine in Elderly Adults Following Documented Herpes Zoster

by Morrison, Vicki A., Oxman, Michael N., Levin, Myron J., Schmader, Kenneth E., Guatelli, John C., Betts, Robert F., Gelb, Larry D., Pachucki, Constance T., Keay, Susan K., Menzies, Barbara, Griffin, Marie R., Kauffman, Carol A., Marques, Adriana R., Toney, John F., Simberkoff, Michael S., Serrao, Richard, Arbeit, Robert D., Gnann, John W., Greenberg, Richard N., Holodniy, Mark, Keitel, Wendy A., Yeh, Shingshing S., Davis, Larry E., Crawford, George E., Neuzil, Kathy M., Johnson, Gary R., Zhang, Jane H., Harbecke, Rith, Chan, Ivan S. F., Keller, Paul M., Williams, Heather M., Boardman, Kathy D., Silber, Jeffrey L., Annunziato, Paula W.
Published in The Journal of infectious diseases

Minimal access surgery compared with medical management for gastro-oesophageal reflux disease: five year follow-up of a randomised controlled trial (REFLUX)

by Grant, A M, Cotton, S C, Boachie, C, Ramsay, C R, Krukowski, Z H, Heading, R C, Campbell, M K
Published in BMJ (Online)

Mitochondrial Disease Sequence Data Resource (MSeqDR): A global grass-roots consortium to facilitate deposition, curation, annotation, and integrated analysis of genomic data for t...

by Falk, Marni J., Shen, Lishuang, Gonzalez, Michael, Leipzig, Jeremy, Lott, Marie T., Stassen, Alphons P.M., Diroma, Maria Angela, Navarro-Gomez, Daniel, Yeske, Philip, Bai, Renkui, Boles, Richard G., Brilhante, Virginia, Ralph, David, DaRe, Jeana T., Shelton, Robert, Terry, Sharon F., Zhang, Zhe, Copeland, William C., van Oven, Mannis, Prokisch, Holger, Wallace, Douglas C., Attimonelli, Marcella, Krotoski, Danuta, Zuchner, Stephan, Gai, Xiaowu, Bale, Sherri, Bedoyan, Jirair, Behar, Doron, Bonnen, Penelope, Brooks, Lisa, Calabrese, Claudia, Calvo, Sarah, Chinnery, Patrick, Christodoulou, John, Church, Deanna, Clima, Rosanna, Cohen, Bruce H., Cotton, Richard G., de Coo, I.F.M., Derbenevoa, Olga, den Dunnen, Johan T., Dimmock, David, Enns, Gregory, Gasparre, Giuseppe, Goldstein, Amy, Gonzalez, Iris, Gwinn, Katrina, Hahn, Sihoun, Haas, Richard H., Hakonarson, Hakon, Hirano, Michio, Kerr, Douglas, Li, Dong, Lvova, Maria, Macrae, Finley, Maglott, Donna, McCormick, Elizabeth, Mitchell, Grant, Mootha, Vamsi K., Okazaki, Yasushi, Pujol, Aurora, Parisi, Melissa, Perin, Juan Carlos, Pierce, Eric A., Procaccio, Vincent, Rahman, Shamima, Reddi, Honey, Rehm, Heidi, Riggs, Erin, Rodenburg, Richard, Rubinstein, Yaffa, Saneto, Russell, Santorsola, Mariangela, Scharfe, Curt, Sheldon, Claire, Shoubridge, Eric A., Simone, Domenico, Smeets, Bert, Smeitink, Jan A., Stanley, Christine, Suomalainen, Anu, Tarnopolsky, Mark, Thiffault, Isabelle, Thorburn, David R., Van Hove, Johan, Wolfe, Lynne, Wong, Lee-Jun
Published in Molecular genetics and metabolism

ODYSSEY clinical trial design: a randomised global study to evaluate the efficacy and safety of dolutegravir-based antiretroviral therapy in HIV-positive children, with nested phar...

by Moore, Cecilia L, Turkova, Anna, Mujuru, Hilda, Kekitiinwa, Adeodata, Lugemwa, Abbas, Kityo, Cissy M, Barlow-Mosha, Linda N, Cressey, Tim R, Violari, Avy, Variava, Ebrahim, Cotton, Mark F, Archary, Moherndran, Compagnucci, Alexandra, Puthanakit, Thanyawee, Behuhuma, Osee, Saϊdi, Yacine, Hakim, James, Amuge, Pauline, Atwine, Lorna, Musiime, Victor, Burger, David M, Shakeshaft, Clare, Giaquinto, Carlo, Rojo, Pablo, Gibb, Diana M, Ford, Deborah
Published in BMC infectious diseases