Clinical targeting of HIV capsid protein with a long-acting small molecule

by Link, John O, Rhee, Martin S, Tse, Winston C, Zheng, Jim, Somoza, John R, Rowe, William, Begley, Rebecca, Chiu, Anna, Mulato, Andrew, Hansen, Derek, Singer, Eric, Tsai, Luong K, Bam, Rujuta A, Chou, Chien-Hung, Canales, Eda, Brizgys, Gediminas, Zhang, Jennifer R, Li, Jiayao, Graupe, Michael, Morganelli, Philip, Liu, Qi, Wu, Qiaoyin, Halcomb, Randall L, Saito, Roland D, Schroeder, Scott D, Lazerwith, Scott E, Bondy, Steven, Jin, Debi, Hung, Magdeleine, Novikov, Nikolai, Liu, Xiaohong, Villaseñor, Armando G, Cannizzaro, Carina E, Hu, Eric Y, Anderson, Robert L, Appleby, Todd C, Lu, Bing, Mwangi, Judy, Liclican, Albert, Niedziela-Majka, Anita, Papalia, Giuseppe A, Wong, Melanie H, Leavitt, Stephanie A, Xu, Yili, Koditek, David, Stepan, George J, Yu, Helen, Pagratis, Nikos, Clancy, Sheila, Ahmadyar, Shekeba, Cai, Terrence Z, Sellers, Scott, Wolckenhauer, Scott A, Ling, John, Callebaut, Christian, Margot, Nicolas, Ram, Renee R, Liu, Ya-Pei, Hyland, Rob, Sinclair, Gary I, Ruane, Peter J, Crofoot, Gordon E, McDonald, Cheryl K, Brainard, Diana M, Lad, Latesh, Swaminathan, Swami, Sundquist, Wesley I, Sakowicz, Roman, Chester, Anne E, Lee, William E, Daar, Eric S, Yant, Stephen R, Cihlar, Tomas
Published in Nature (London)

Noninvasive measurement of blood pressure in conscious cynomolgus monkeys

by Chester, Anne E., Dorr, Albert E., Lund, Kevin R., Wood, Larry D.
Published in Fundamental and applied toxicology

Acute and subchronic toxicity studies with detirelix, a luteinizing hormone-releasing hormone antagonist, in the rat and monkey

by Chester, Anne E., Fairchild, David G., Depass, Linval R.
Published in Fundamental and applied toxicology

Robust continuous in vitro culture of the Plasmodium cynomolgi erythrocytic stages

by Chua, Adeline C Y, Ong, Jessica Jie Ying, Malleret, Benoit, Suwanarusk, Rossarin, Kosaisavee, Varakorn, Zeeman, Anne-Marie, Cooper, Caitlin A, Tan, Kevin S W, Zhang, Rou, Tan, Bee Huat, Abas, Siti Nurdiana, Yip, Andy, Elliot, Anne, Joyner, Chester J, Cho, Jee Sun, Breyer, Kate, Baran, Szczepan, Lange, Amber, Maher, Steven P, Nosten, François, Bodenreider, Christophe, Yeung, Bryan K S, Mazier, Dominique, Galinski, Mary R, Dereuddre-Bosquet, Nathalie, Le Grand, Roger, Kocken, Clemens H M, Rénia, Laurent, Kyle, Dennis E, Diagana, Thierry T, Snounou, Georges, Russell, Bruce, Bifani, Pablo
Published in Nature communications

Early AD pathology in a [C-11]PiB-negative case: a PiB-amyloid imaging, biochemical, and immunohistochemical study

by Ikonomovic, Milos D., Abrahamson, Eric E., Price, Julie C., Hamilton, Ronald L., Mathis, Chester A., Paljug, William R., Debnath, Manik L., Cohen, Anne D., Mizukami, Katsuyoshi, DeKosky, Steven T., Lopez, Oscar L., Klunk, William E.
Published in Acta neuropathologica

Mutations in PURA Cause Profound Neonatal Hypotonia, Seizures, and Encephalopathy in 5q31.3 Microdeletion Syndrome

by Lalani, Seema R., Zhang, Jing, Schaaf, Christian P., Brown, Chester W., Magoulas, Pilar, Tsai, Anne Chun-Hui, El-Gharbawy, Areeg, Wierenga, Klaas J., Bartholomew, Dennis, Fong, Chin-To, Barbaro-Dieber, Tina, Kukolich, Mary K., Burrage, Lindsay C., Austin, Elise, Keller, Kory, Pastore, Matthew, Fernandez, Fabio, Lotze, Timothy, Wilfong, Angus, Purcarin, Gabriela, Zhu, Wenmiao, Craigen, William J., McGuire, Marianne, Jain, Mahim, Cooney, Erin, Azamian, Mahshid, Bainbridge, Matthew N., Muzny, Donna M., Boerwinkle, Eric, Person, Richard E., Niu, Zhiyv, Eng, Christine M., Lupski, James R., Gibbs, Richard A., Beaudet, Arthur L., Yang, Yaping, Wang, Meng C., Xia, Fan
Published in American journal of human genetics

Patterns, processes and vulnerability of Southern Ocean benthos: a decadal leap in knowledge and understanding

by Kaiser, Stefanie, Brandão, Simone N., Brix, Saskia, Barnes, David K. A., Bowden, David A., Ingels, Jeroen, Leese, Florian, Schiaparelli, Stefano, Arango, Claudia P., Badhe, Renuka, Bax, Narissa, Blazewicz-Paszkowycz, Magdalena, Brandt, Angelika, Brenke, Nils, Catarino, Ana I., David, Bruno, De Ridder, Chantal, Dubois, Philippe, Ellingsen, Kari E., Glover, Adrian G., Griffiths, Huw J., Gutt, Julian, Halanych, Kenneth M., Havermans, Charlotte, Held, Christoph, Janussen, Dorte, Lörz, Anne-Nina, Pearce, David A., Pierrat, Benjamin, Riehl, Torben, Rose, Armin, Sands, Chester J., Soler-Membrives, Anna, Schüller, Myriam, Strugnell, Jan M., Vanreusel, Ann, Veit-Köhler, Gritta, Wilson, Nerida G., Yasuhara, Moriaki
Published in Marine biology

Improved ligand-binding- and signaling-competent human NK2R yields in yeast using a chimera with the rat NK2R C-terminus enable NK2R-G protein signaling platform

by Jain, Abhinav R, Britton, Zachary T, Markwalter, Chester E, Robinson, Anne S
Published in Protein engineering, design and selection

Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation

by Soroosh, Pejman, Wu, Jiejun, Xue, Xiaohua, Song, Jiao, Sutton, Steven W., Sablad, Marciano, Yu, Jingxue, Nelen, Marina I., Liu, Xuejun, Castro, Glenda, Luna, Rosa, Crawford, Shelby, Banie, Homayon, Dandridge, Rose A., Deng, Xiaohu, Bittner, Anton, Kuei, Chester, Tootoonchi, Mandana, Rozenkrants, Natasha, Herman, Krystal, Gao, Jingjin, Yang, Xia V., Sachen, Kacey, Ngo, Karen, Fung-Leung, Wai-Ping, Nguyen, Steven, de Leon-Tabaldo, Aimee, Blevitt, Jonathan, Zhang, Yan, Cummings, Maxwell D., Rao, Tadimeti, Mani, Neelakandha S., Liu, Changlu, McKinnon, Murray, Milla, Marcos E., Fourie, Anne M., Sun, Siquan
Published in Proceedings of the National Academy of Sciences - PNAS

Safety and efficacy of avalglucosidase alfa versus alglucosidase alfa in patients with late-onset Pompe disease (COMET): a phase 3, randomised, multicentre trial

by Diaz-Manera, Jordi, Kishnani, Priya S, Ladha, Shafeeq, Mozaffar, Tahseen, Straub, Volker, Berger, Kenneth I, Chien, Yin-Hsiu, Day, John W, Illarioshkin, Sergey, Roberts, Mark, Attarian, Shahram, Borges, Joao Lindolfo, Choi, Young Chul, Goker-Alpan, Ozlem, Kostera-Pruszczyk, Anna, Haack, Kristina An, Hug, Christopher, Huynh-Ba, Olivier, Johnson, Judith, Thibault, Nathan, Zhou, Tianyue, Dimachkie, Mazen M, Behin, Anthony, Boentert, Matthias, Carvalho, Gerson, Chahin, Nizar, Deegan, Patrick, Duval, Fanny, Genge, Angela, Gutmann, Ludwig, Henderson, Robert D, Hennermann, Julia B, Hiwot, Tarekegn, Hughes, Derralynn, Karaa, Amel, Komaki, Hirofumi, Longo, Nicola, Malinova, Vera, Maxit, Clarisa, Mengel, Eugen, Moggio, Maurizio Gualtiero, Mongini, Tiziana Enrica, Nascimento Osorio, Andres, Noury, Jean-Baptiste, Oliveira, Acary Souza Bulle, Pena, Loren, Remiche, Gauthier, Sciacco, Monica, Smith, Cheryl, Stulnig, Thomas, Taithe, Frederic, Tarnopolsky, Mark, Young, Peter, Alonso-Pérez, Jorge, Altemus, Patricia, Aubé-Nathier, Anne-Catherine, Avelar, Jennifer B, Billy, Jenny, Boschi, Silvia, Carrera Garcia, Laura, Chase, Lauren, Danjoux, Loïc, Davion, Jean-Baptiste, DeArmey, Stephanie, Gandolfo, Eve, Grosz, Zoltan, Guellec, Dewi, Guettsches, Anne-Katrin, Guglieri, Michela, Hatcher, Erin, Hufgard-Leitner, Miriam, Klyushnikov, Sergey A., Langton, Jacqui, Linková, Lenka, Mavroudakis, Nicolas, Mazurová, Stella, Mori, Madoka, Müller-Miny, Louisa, Natera-de Benito, Daniel, Neel, Robert, Niizawa, Gabriela A, Noll, Lauren, Pasnoor, Mamatha, Questienne, Claire, Ramos Lopes, Margarida, Riedl, Michaela, Salort-Campana, Emmanuelle, Sole, Guilhem, Solera, Luca, Souto Lopes, Suzara, Specht, Sabine, Statland, Jeffrey, Swenson, Andrea, Tan, Chong Yew, Tizon, Sónia, van der Beek, N A M E, van Kooten, Harmke A., Wencel, Marie, Wenninger, Stephan, Zagnoli, Fabien
Published in Lancet neurology

Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function

by Buchan, Sarah L., Dou, Lang, Remer, Marcus, Booth, Steven G., Dunn, Stuart N., Lai, Chester, Semmrich, Monika, Teige, Ingrid, Mårtensson, Linda, Penfold, Christine A., Chan, H.T. Claude, Willoughby, Jane E., Mockridge, C. Ian, Dahal, Lekh N., Cleary, Kirstie L.S., James, Sonya, Rogel, Anne, Kannisto, Päivi, Jernetz, Mats, Williams, Emily L., Healy, Eugene, Verbeek, J. Sjef, Johnson, Peter W.M., Frendéus, Björn, Cragg, Mark S., Glennie, Martin J., Gray, Juliet C., Al-Shamkhani, Aymen, Beers, Stephen A.
Published in Immunity (Cambridge, Mass.)

Is it feasible to treat painful hand osteoarthritis with menopausal hormonal treatment? Results from a randomised controlled trial (the HOPE-e study)

by Williams, Jennifer A.E., Chester-Jones, Mae, Brewer, Gretchen, Francis, Anne, Lamb, Sarah E., Vincent, Tonia L., Vincent, Katy, Dutton, Susan J., Watt, Fiona E.
Published in Maturitas

Growth Hormone (GH) Replacement Therapy in Adult-Onset GH Deficiency: Effects on Body Composition in Men and Women in a Double-Blind, Randomized, Placebo-Controlled Trial

by Hoffman, Andrew R, Kuntze, Joyce E, Baptista, Joyce, Baum, Howard B. A, Baumann, Gerhard P, Biller, Beverly M. K, Clark, Richard V, Cook, David, Inzucchi, Silvio E, Kleinberg, David, Klibanski, Anne, Phillips, Lawrence S, Ridgway, E. Chester, Robbins, Richard J, Schlechte, Janet, Sharma, Meeta, Thorner, Michael O, Vance, Mary Lee
Published in The journal of clinical endocrinology and metabolism

Mutations in DCHS1 cause mitral valve prolapse

by Durst, Ronen, Sauls, Kimberly, Peal, David S, deVlaming, Annemarieke, Toomer, Katelynn, Leyne, Maire, Salani, Monica, Talkowski, Michael E, Brand, Harrison, Perrocheau, Maëlle, Simpson, Charles, Jett, Christopher, Stone, Matthew R, Charles, Florie, Chiang, Colby, Lynch, Stacey N, Bouatia-Naji, Nabila, Delling, Francesca N, Freed, Lisa A, Tribouilloy, Christophe, Le Tourneau, Thierry, LeMarec, Hervé, Fernandez-Friera, Leticia, Solis, Jorge, Trujillano, Daniel, Ossowski, Stephan, Estivill, Xavier, Dina, Christian, Bruneval, Patrick, Chester, Adrian, Schott, Jean-Jacques, Irvine, Kenneth D, Mao, Yaopan, Wessels, Andy, Motiwala, Tahirali, Puceat, Michel, Tsukasaki, Yoshikazu, Menick, Donald R, Kasiganesan, Harinath, Nie, Xingju, Broome, Ann-Marie, Williams, Katherine, Johnson, Amanda, Markwald, Roger R, Jeunemaitre, Xavier, Hagege, Albert, Levine, Robert A, Milan, David J, Norris, Russell A, Slaugenhaupt, Susan A
Published in Nature (London)

Phase I/II Trial of Carboplatin and Paclitaxel Chemotherapy in Combination with Intravenous Oncolytic Reovirus in Patients with Advanced Malignancies

by KARAPANAGIOTOU, Eleni M, ROULSTONE, Victoria, COFFEY, Matt, THOMPSON, Brad, METTINGER, Karl, VILE, Richard G, PANDHA, Hardev S, HALL, Geoff D, MELCHER, Alan A, CHESTER, John, HARRINGTON, Kevin J, TWIGGER, Katie, BALL, Mercel, TANAY, Maryanne, NUTTING, Chris, NEWBOLD, Kate, GORE, Martin E, LARKIN, James, SYRIGOS, Konstantinos N
Published in Clinical cancer research

Hand Osteoarthritis: investigating Pain Effects of estrogen-containing therapy (HOPE-e): a protocol for a feasibility randomised placebo-controlled trial

by Marian, Ioana R, Goff, Megan, Williams, Jennifer A E, Gulati, Malvika, Chester-Jones, Mae, Francis, Anne, Watson, Marion, Vincent, Tonia L, Woollacott, Sue, Mackworth-Young, Charles, Glover, Victoria, Furniss, Dominic, Gardiner, Matthew, Lamb, Sarah E, Vincent, Katy, Barber, Vicki S, Black, Joanna, Dutton, Susan J, Watt, Fiona E
Published in Pilot and feasibility studies

Enzyme replacement therapy for mucopolysaccharidosis VI: long-term cardiac effects of galsulfase (Naglazyme®) therapy

by Braunlin, E., Rosenfeld, H., Kampmann, C., Johnson, J., Beck, M., Giugliani, R., Guffon, N., Ketteridge, D., Sá Miranda, C. M., Scarpa, M., Schwartz, I. V., Leão Teles, E., Wraith, J. E., Barrios, P., Dias da Silva, E., Kurio, G., Richardson, M., Gildengorin, G., Hopwood, J. J., Imperiale, M., Schatz, A., Decker, C., Harmatz, P.
Published in Journal of inherited metabolic disease

Prognostic Factors in Typical and Atypical Pulmonary Carcinoids

by Ramirez, Robert A, Beyer, David T, Diebold, Anne E, Voros, Brianne A, Chester, Maria M, Wang, Yi-Zarn, Boudreaux, J Philip, Woltering, Eugene A, Uhlhorn, Ann-Porter, Ryan, Pamela, Campeau, Richard J, Anthony, Lowell B
Published in The Ochsner journal

The limnology and biology of the Dufek Massif, Transantarctic Mountains 82° South

by Hodgson, Dominic A., Convey, Peter, Verleyen, Elie, Vyverman, Wim, McInnes, Sandra J., Sands, Chester J., Fernández-Carazo, Rafael, Wilmotte, Annick, De Wever, Aaike, Peeters, Karolien, Tavernier, Ines, Willems, Anne
Published in Polar science

Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium–Down Syndrom...

by Petersen, Melissa E., Zhang, Fan, Schupf, Nicole, Krinsky‐McHale, Sharon J., Hall, James, Mapstone, Mark, Cheema, Amrita, Silverman, Wayne, Lott, Ira, Rafii, Michael S., Handen, Benjamin, Klunk, William, Head, Elizabeth, Christian, Brad, Foroud, Tatiana, Lai, Florence, Rosas, H. Diana, Zaman, Shahid, Ances, Beau M., Wang, Mei‐Cheng, Tycko, Benjamin, Lee, Joseph H., O'Bryant, Sid
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring