Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 expression

by La Belle Flynn, Alyssa, Calhoun, Benjamin C, Sharma, Arishya, Chang, Jenny C, Almasan, Alexandru, Schiemann, William P
Published in Nature communications

A targetable LIFR-NF-κB-LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis

by Yao, Fan, Deng, Yalan, Zhao, Yang, Mei, Ying, Zhang, Yilei, Liu, Xiaoguang, Martinez, Consuelo, Su, Xiaohua, Rosato, Roberto R, Teng, Hongqi, Hang, Qinglei, Yap, Shannon, Chen, Dahu, Wang, Yumeng, Chen, Mei-Ju May, Zhang, Mutian, Liang, Han, Xie, Dong, Chen, Xin, Zhu, Hao, Chang, Jenny C, You, M James, Sun, Yutong, Gan, Boyi, Ma, Li
Published in Nature communications

Molecular characterization of breast cancer CTCs associated with brain metastasis

by Boral, Debasish, Vishnoi, Monika, Liu, Haowen N, Yin, Wei, Sprouse, Marc L, Scamardo, Antonio, Hong, David S, Tan, Tuan Z, Thiery, Jean P, Chang, Jenny C, Marchetti, Dario
Published in Nature communications

Identification of nine new susceptibility loci for endometrial cancer

by Glubb, Dylan M, Amant, Frederic, Annibali, Daniela, Ashton, Katie, Attia, John, Auer, Paul L, Beckmann, Matthias W, Black, Amanda, Brauch, Hiltrud, Brenner, Hermann, Brinton, Louise, Buchanan, Daniel D, Burwinkel, Barbara, Chanock, Stephen J, Chen, Chu, Chen, Maxine M, Cheng, Timothy H T, Clarke, Christine L, Clendenning, Mark, Cook, Linda S, Couch, Fergus J, Czene, Kamila, Day, Felix, Dennis, Joe, Depreeuw, Jeroen, Dörk, Thilo, Dowdy, Sean C, Dürst, Matthias, Ekici, Arif B, Fasching, Peter A, Fridley, Brooke L, Friedenreich, Christine M, Fung, Jenny, Gaudet, Mia M, Giles, Graham G, Goode, Ellen L, Gorman, Maggie, Haiman, Christopher A, Hankison, Susan E, Healey, Catherine S, Hein, Alexander, Hillemanns, Peter, Hodgson, Shirley, Hoivik, Erling A, Holliday, Elizabeth G, Jones, Angela, Krakstad, Camilla, Lambrechts, Diether, Lindblom, Annika, Lissowska, Jolanta, Long, Jirong, Lu, Lingeng, Magliocco, Anthony M, Martin, Lynn, Meindl, Alfons, Michailidou, Kyriaki, Milne, Roger L, Mints, Miriam, Nassir, Rami, Orlow, Irene, Otton, Geoffrey, Palles, Claire, Perry, John R B, Prescott, Jennifer, Proietto, Tony, Rebbeck, Timothy R, Risch, Harvey A, Rogers, Peter A W, Rübner, Matthias, Runnebaum, Ingo, Sacerdote, Carlotta, Sarto, Gloria E, Schumacher, Fredrick, Setiawan, V Wendy, Sheng, Xin, Shu, Xiao-Ou, Southey, Melissa C, Swerdlow, Anthony J, Tham, Emma, Trovik, Jone, Turman, Constance, Tyrer, Jonathan P, Vachon, Celine, Vanderstichele, Adriaan, Wang, Zhaoming, Webb, Penelope M, Wentzensen, Nicolas, Werner, Henrica M J, Winham, Stacey J, Xia, Lucy, Yang, Hannah P, Yu, Herbert, Zheng, Wei, Pharoah, Paul D P, Kraft, Peter, De Vivo, Immaculata, Tomlinson, Ian, Easton, Douglas F, Spurdle, Amanda B, Thompson, Deborah J
Published in Nature communications

Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis

by Papadimitriou, Nikos, Dimou, Niki, Tsilidis, Konstantinos K, Banbury, Barbara, Martin, Richard M, Lewis, Sarah J, Kazmi, Nabila, Robinson, Timothy M, Albanes, Demetrius, Aleksandrova, Krasimira, Berndt, Sonja I, Timothy Bishop, D, Brenner, Hermann, Buchanan, Daniel D, Bueno-de-Mesquita, Bas, Campbell, Peter T, Castellví-Bel, Sergi, Chan, Andrew T, Chang-Claude, Jenny, Ellingjord-Dale, Merete, Figueiredo, Jane C, Gallinger, Steven J, Giles, Graham G, Giovannucci, Edward, Gruber, Stephen B, Gsur, Andrea, Hampe, Jochen, Hampel, Heather, Harlid, Sophia, Harrison, Tabitha A, Hoffmeister, Michael, Hopper, John L, Hsu, Li, María Huerta, José, Huyghe, Jeroen R, Jenkins, Mark A, Keku, Temitope O, Kühn, Tilman, La Vecchia, Carlo, Le Marchand, Loic, Li, Christopher I, Li, Li, Lindblom, Annika, Lindor, Noralane M, Lynch, Brigid, Markowitz, Sanford D, Masala, Giovanna, May, Anne M, Milne, Roger, Monninkhof, Evelyn, Moreno, Lorena, Moreno, Victor, Newcomb, Polly A, Offit, Kenneth, Perduca, Vittorio, Pharoah, Paul D P, Platz, Elizabeth A, Potter, John D, Rennert, Gad, Riboli, Elio, Sánchez, Maria-Jose, Schmit, Stephanie L, Schoen, Robert E, Severi, Gianluca, Sieri, Sabina, Slattery, Martha L, Song, Mingyang, Tangen, Catherine M, Thibodeau, Stephen N, Travis, Ruth C, Trichopoulou, Antonia, Ulrich, Cornelia M, van Duijnhoven, Franzel J B, Van Guelpen, Bethany, Vodicka, Pavel, White, Emily, Wolk, Alicja, Woods, Michael O, Wu, Anna H, Peters, Ulrike, Gunter, Marc J, Murphy, Neil
Published in Nature communications

Haploinsufficiency in the ANKS1B gene encoding AIDA-1 leads to a neurodevelopmental syndrome

by Carbonell, Abigail U, Cho, Chang Hoon, Tindi, Jaafar O, Counts, Pamela A, Bates, Juliana C, Erdjument-Bromage, Hediye, Cvejic, Svetlana, Iaboni, Alana, Kvint, Ifat, Rosensaft, Jenny, Banne, Ehud, Anagnostou, Evdokia, Neubert, Thomas A, Scherer, Stephen W, Molholm, Sophie, Jordan, Bryen A
Published in Nature communications

Association analyses identify 31 new risk loci for colorectal cancer susceptibility

by Law, Philip J, Timofeeva, Maria, Fernandez-Rozadilla, Ceres, Broderick, Peter, Studd, James, Fernandez-Tajes, Juan, Farrington, Susan, Svinti, Victoria, Palles, Claire, Orlando, Giulia, Sud, Amit, Holroyd, Amy, Penegar, Steven, Theodoratou, Evropi, Vaughan-Shaw, Peter, Campbell, Harry, Zgaga, Lina, Hayward, Caroline, Campbell, Archie, Harris, Sarah, Deary, Ian J, Starr, John, Gatcombe, Laura, Pinna, Maria, Briggs, Sarah, Martin, Lynn, Jaeger, Emma, Sharma-Oates, Archana, East, James, Leedham, Simon, Arnold, Roland, Johnstone, Elaine, Wang, Haitao, Kerr, David, Kerr, Rachel, Maughan, Tim, Kaplan, Richard, Al-Tassan, Nada, Palin, Kimmo, Hänninen, Ulrika A, Cajuso, Tatiana, Tanskanen, Tomas, Kondelin, Johanna, Kaasinen, Eevi, Sarin, Antti-Pekka, Eriksson, Johan G, Rissanen, Harri, Knekt, Paul, Pukkala, Eero, Jousilahti, Pekka, Salomaa, Veikko, Ripatti, Samuli, Palotie, Aarno, Renkonen-Sinisalo, Laura, Lepistö, Anna, Böhm, Jan, Mecklin, Jukka-Pekka, Buchanan, Daniel D, Win, Aung-Ko, Hopper, John, Jenkins, Mark E, Lindor, Noralane M, Newcomb, Polly A, Gallinger, Steven, Duggan, David, Casey, Graham, Hoffmann, Per, Nöthen, Markus M, Jöckel, Karl-Heinz, Easton, Douglas F, Pharoah, Paul D P, Peto, Julian, Canzian, Federico, Swerdlow, Anthony, Eeles, Rosalind A, Kote-Jarai, Zsofia, Muir, Kenneth, Pashayan, Nora, Harkin, Andrea, Allan, Karen, McQueen, John, Paul, James, Iveson, Timothy, Saunders, Mark, Butterbach, Katja, Chang-Claude, Jenny, Hoffmeister, Michael, Brenner, Hermann, Kirac, Iva, Matošević, Petar, Hofer, Philipp, Brezina, Stefanie, Gsur, Andrea, Cheadle, Jeremy P, Aaltonen, Lauri A, Tomlinson, Ian, Houlston, Richard S, Dunlop, Malcolm G
Published in Nature communications

Epigenetic regulation of diacylglycerol kinase alpha promotes radiation-induced fibrosis

by Weigel, Christoph, Veldwijk, Marlon R, Oakes, Christopher C, Seibold, Petra, Slynko, Alla, Liesenfeld, David B, Rabionet, Mariona, Hanke, Sabrina A, Wenz, Frederik, Sperk, Elena, Benner, Axel, Rösli, Christoph, Sandhoff, Roger, Assenov, Yassen, Plass, Christoph, Herskind, Carsten, Chang-Claude, Jenny, Schmezer, Peter, Popanda, Odilia
Published in Nature communications

The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration

by Gdynia, Georg, Sauer, Sven W, Kopitz, Jürgen, Fuchs, Dominik, Duglova, Katarina, Ruppert, Thorsten, Miller, Matthias, Pahl, Jens, Cerwenka, Adelheid, Enders, Markus, Mairbäurl, Heimo, Kamiński, Marcin M, Penzel, Roland, Zhang, Christine, Fuller, Jonathan C, Wade, Rebecca C, Benner, Axel, Chang-Claude, Jenny, Brenner, Hermann, Hoffmeister, Michael, Zentgraf, Hanswalter, Schirmacher, Peter, Roth, Wilfried
Published in Nature communications

Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers

by Zhang, Yan Dora, Hurson, Amber N, Zhang, Haoyu, Choudhury, Parichoy Pal, Easton, Douglas F, Milne, Roger L, Simard, Jacques, Hall, Per, Michailidou, Kyriaki, Dennis, Joe, Schmidt, Marjanka K, Chang-Claude, Jenny, Gharahkhani, Puya, Whiteman, David, Campbell, Peter T, Hoffmeister, Michael, Jenkins, Mark, Peters, Ulrike, Hsu, Li, Gruber, Stephen B, Casey, Graham, Schmit, Stephanie L, O'Mara, Tracy A, Spurdle, Amanda B, Thompson, Deborah J, Tomlinson, Ian, De Vivo, Immaculata, Landi, Maria Teresa, Law, Matthew H, Iles, Mark M, Demenais, Florence, Kumar, Rajiv, MacGregor, Stuart, Bishop, D Timothy, Ward, Sarah V, Bondy, Melissa L, Houlston, Richard, Wiencke, John K, Melin, Beatrice, Barnholtz-Sloan, Jill, Kinnersley, Ben, Wrensch, Margaret R, Amos, Christopher I, Hung, Rayjean J, Brennan, Paul, McKay, James, Caporaso, Neil E, Berndt, Sonja I, Birmann, Brenda M, Camp, Nicola J, Kraft, Peter, Rothman, Nathaniel, Slager, Susan L, Berchuck, Andrew, Pharoah, Paul D P, Sellers, Thomas A, Gayther, Simon A, Pearce, Celeste L, Goode, Ellen L, Schildkraut, Joellen M, Moysich, Kirsten B, Amundadottir, Laufey T, Jacobs, Eric J, Klein, Alison P, Petersen, Gloria M, Risch, Harvey A, Stolzenberg-Solomon, Rachel Z, Wolpin, Brian M, Li, Donghui, Eeles, Rosalind A, Haiman, Christopher A, Kote-Jarai, Zsofia, Schumacher, Fredrick R, Al Olama, Ali Amin, Purdue, Mark P, Scelo, Ghislaine, Dalgaard, Marlene D, Greene, Mark H, Grotmol, Tom, Kanetsky, Peter A, McGlynn, Katherine A, Nathanson, Katherine L, Turnbull, Clare, Wiklund, Fredrik, Chanock, Stephen J, Chatterjee, Nilanjan, Garcia-Closas, Montserrat
Published in Nature communications

Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival

by Zaidi, Syed H, Harrison, Tabitha A, Phipps, Amanda I, Steinfelder, Robert, Trinh, Quang M, Qu, Conghui, Banbury, Barbara L, Georgeson, Peter, Grasso, Catherine S, Giannakis, Marios, Adams, Jeremy B, Alwers, Elizabeth, Amitay, Efrat L, Barfield, Richard T, Berndt, Sonja I, Borozan, Ivan, Brenner, Hermann, Brezina, Stefanie, Buchanan, Daniel D, Cao, Yin, Chan, Andrew T, Chang-Claude, Jenny, Connolly, Charles M, Drew, David A, Farris, 3rd, Alton Brad, Figueiredo, Jane C, French, Amy J, Fuchs, Charles S, Garraway, Levi A, Gruber, Steve, Guinter, Mark A, Hamilton, Stanley R, Harlid, Sophia, Heisler, Lawrence E, Hidaka, Akihisa, Hopper, John L, Huang, Wen-Yi, Huyghe, Jeroen R, Jenkins, Mark A, Krzyzanowski, Paul M, Lemire, Mathieu, Lin, Yi, Luo, Xuemei, Mardis, Elaine R, McPherson, John D, Miller, Jessica K, Moreno, Victor, Mu, Xinmeng Jasmine, Nishihara, Reiko, Papadopoulos, Nickolas, Pasternack, Danielle, Quist, Michael J, Rafikova, Adilya, Reid, Emma E G, Shinbrot, Eve, Shirts, Brian H, Stein, Lincoln D, Teney, Cherie D, Timms, Lee, Um, Caroline Y, Van Guelpen, Bethany, Van Tassel, Megan, Wang, Xiaolong, Wheeler, David A, Yung, Christina K, Hsu, Li, Ogino, Shuji, Gsur, Andrea, Newcomb, Polly A, Gallinger, Steven, Hoffmeister, Michael, Campbell, Peter T, Thibodeau, Stephen N, Sun, Wei, Hudson, Thomas J, Peters, Ulrike
Published in Nature communications

Genome-wide association study of colorectal cancer identifies six new susceptibility loci

by Schumacher, Fredrick R, Schmit, Stephanie L, Jiao, Shuo, Edlund, Christopher K, Wang, Hansong, Zhang, Ben, Hsu, Li, Huang, Shu-Chen, Fischer, Christopher P, Harju, John F, Idos, Gregory E, Lejbkowicz, Flavio, Manion, Frank J, McDonnell, Kevin, McNeil, Caroline E, Melas, Marilena, Rennert, Hedy S, Shi, Wei, Thomas, Duncan C, Van Den Berg, David J, Hutter, Carolyn M, Aragaki, Aaron K, Butterbach, Katja, Caan, Bette J, Carlson, Christopher S, Chanock, Stephen J, Curtis, Keith R, Fuchs, Charles S, Gala, Manish, Giovannucci, Edward L, Gogarten, Stephanie M, Hayes, Richard B, Henderson, Brian, Hunter, David J, Jackson, Rebecca D, Kolonel, Laurence N, Kooperberg, Charles, Küry, Sébastien, LaCroix, Andrea, Laurie, Cathy C, Laurie, Cecelia A, Lemire, Mathieu, Levine, David, Ma, Jing, Makar, Karen W, Qu, Conghui, Taverna, Darin, Ulrich, Cornelia M, Wu, Kana, Kono, Suminori, West, Dee W, Berndt, Sonja I, Bezieau, Stéphane, Brenner, Hermann, Campbell, Peter T, Chan, Andrew T, Chang-Claude, Jenny, Coetzee, Gerhard A, Conti, David V, Duggan, David, Figueiredo, Jane C, Fortini, Barbara K, Gallinger, Steven J, Gauderman, W James, Giles, Graham, Green, Roger, Haile, Robert, Harrison, Tabitha A, Hoffmeister, Michael, Hopper, John L, Hudson, Thomas J, Jacobs, Eric, Iwasaki, Motoki, Jee, Sun Ha, Jenkins, Mark, Jia, Wei-Hua, Joshi, Amit, Li, Li, Lindor, Noralene M, Matsuo, Keitaro, Moreno, Victor, Mukherjee, Bhramar, Newcomb, Polly A, Potter, John D, Raskin, Leon, Rennert, Gad, Rosse, Stephanie, Severi, Gianluca, Schoen, Robert E, Seminara, Daniela, Shu, Xiao-Ou, Slattery, Martha L, Tsugane, Shoichiro, White, Emily, Xiang, Yong-Bing, Zanke, Brent W, Zheng, Wei, Le Marchand, Loic, Casey, Graham, Gruber, Stephen B
Published in Nature communications

Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes

by Guo, Xingyi, Tao, Ran, Huyghe, Jeroen R, Law, Philip J, Ping, Jie, Long, Jirong, Díez-Obrero, Virginia, Fernandez-Tajes, Juan, Palles, Claire, Sherwood, Kitty, Briggs, Sarah E W, Donnelly, Kevin, Farrington, Susan M, Vaughan-Shaw, Peter G, Lu, Yingchang, Harrison, Tabitha A, Conti, David V, Schumacher, Fredrick R, Rennert, Gad, Obón-Santacana, Mireia, Martín-Sánchez, Vicente, Kim, Jeongseon, Jee, Sun Ha, Jung, Keum Ji, Kweon, Sun-Seog, Shin, Min-Ho, Kim, Dong-Hyun, Wen, Wanqing, Matsuo, Keitaro, Matsuda, Koichi, Jia, Wei-Hua, Jenkins, Mark A, Win, Aung Ko, Figueiredo, Jane C, Haile, Robert W, Gallinger, Steven, Woods, Michael O, Duggan, David, Kaplan, Richard, Kerr, David, Jousilahti, Pekka, Pukkala, Eero, Eriksson, Johan G, Hänninen, Ulrika, Kondelin, Johanna, Palin, Kimmo, Tanskanen, Tomas, Renkonen-Sinisalo, Laura, Weinstein, Stephanie J, Palmer, Julie R, Buchanan, Daniel D, Siegel, Erin, Campbell, Peter T, Chang-Claude, Jenny, Hoffmeister, Michael, Brenner, Hermann, Tsilidis, Kostas K, Schulze, Matthias B, Shcherbina, Anna, Giles, Graham G, Southey, Melissa C, Idos, Gregory E, Shulman, Katerina, Su, Yu-Ru, Steinfelder, Robert, Keku, Temitope O, van Guelpen, Bethany, Pearlman, Rachel, Martinez, Marie Elena, White, Emily, Li, Li, Doheny, Kimberly F, Shelford, Tameka, Chan, Andrew T, Cruz-Correa, Marcia, Stadler, Zsofia K, Edlund, Christopher K, Kim, Andre, Feskens, Edith J M, Sakoda, Lori C, Pardini, Barbara, FitzGerald, Liesel M, Lee, Soo Chin, Li, Christopher I, Lin, Yi, Prentice, Ross, Bézieau, Stéphane, Sawada, Norie, Wu, Anna H, Coetzee, Gerhard, Hayward, Caroline, Deary, Ian J, Harris, Sarah E, Reid, Stuart, Walker, Marion, Ooi, Li Yin, Lau, Ken S, Gruber, Stephen B, Houlston, Richard S, Peters, Ulrike
Published in Nature communications

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

by Song, Honglin, Lawrenson, Kate, Ramus, Susan J, Cicek, Mine S, Tyrer, Jonathan, Stram, Douglas, Wozniak, Eva L, Wik, Elisabeth, Whittemore, Alice S, Weber, Rachel Palmieri, Vitonis, Allison F, Vergote, Ignace, Van Den Berg, David, Van Altena, Anne M, Tworoger, Shelley S, Thompson, Pamela J, Tessier, Daniel C, Teo, Soo-Hwang, Templeman, Claire, Stram, Daniel O, Southey, Melissa C, Siddiqui, Nadeem, Shu, Xiao-Ou, Shridhar, Viji, Severi, Gianluca, Schwaab, Ira, Rzepecka, Iwona K, Runnebaum, Ingo B, Rossing, Mary Anne, Rodriguez-Rodriguez, Lorna, Renner, Stefan P, Poole, Elizabeth M, Pike, Malcolm C, Pelttari, Liisa M, Pejovic, Tanja, Paul, James, Orlow, Irene, Odunsi, Kunle, Nevanlinna, Heli, Ness, Roberta B, Nakanishi, Toru, Moysich, Kirsten B, Monteiro, Alvaro N A, Moes-Sosnowska, Joanna, Modugno, Francesmary, Menon, Usha, Massuger, Leon F A G, Lundvall, Lene, Lissowska, Jolanta, Kupryjanczyk, Jolanta, Krakstad, Camilla, Konecny, Gottfried E, Kjaer, Susanne Krüger, Kiemeney, Lambertus A, Karlan, Beth Y, Karevan, Rod, Kalli, Kimberly R, Kajiyama, Hiroaki, Ji, Bu-Tian, Høgdall, Claus K, Hoatlin, Maureen, Hein, Rebecca, Hall, Per, Gronwald, Jacek, Gore, Martin, Goodman, Marc T, Giles, Graham G, Gentry-Maharaj, Aleksandra, Garcia-Closas, Montserrat, Flanagan, James M, Fasching, Peter A, Ekici, Arif B, Edwards, Robert, Eccles, Diana, Easton, Douglas F, Dürst, Matthias, du Bois, Andreas, Dörk, Thilo, Despierre, Evelyn, Cramer, Daniel W, Cook, Linda S, Chen, Xiaoqing, Charbonneau, Bridget, Chang-Claude, Jenny, Bunker, Clareann H, Brueggmann, Doerthe, Brown, Robert, Brooks-Wilson, Angela, Brinton, Louise A, Bogdanova, Natalia, Beesley, Jonathan, Beckmann, Matthias W, Baglietto, Laura, Bacot, François, Armasu, Sebastian M, Antonenkova, Natalia, Wu, Xifeng, Hildebrandt, Michelle A T, Sellers, Thomas A, Pearce, Celeste Leigh
Published in Nature communications

A network analysis to identify mediators of germline-driven differences in breast cancer prognosis

by Abraham, Jean, Andrulis, Irene L, Anton-Culver, Hoda, Arndt, Volker, Ashworth, Alan, Auvinen, Päivi, Beckmann, Matthias W, Beesley, Jonathan, Behrens, Sabine, Benitez, Javier, Bermisheva, Marina, Blomqvist, Carl, Blot, William, Bogdanova, Natalia V, Bojesen, Stig E, Bolla, Manjeet K, Brauch, Hiltrud, Brenner, Hermann, Brucker, Sara Y, Burwinkel, Barbara, Caldas, Carlos, Chin, Suet-Feung, Clarke, Christine L, Couch, Fergus J, Cox, Angela, Czene, Kamila, Daly, Mary B, Dennis, Joe, Devilee, Peter, Dunning, Alison M, Dwek, Miriam, Eliassen, A Heather, Ellberg, Carolina, Evans, D Gareth, Fasching, Peter A, Flyger, Henrik, Gago-Dominguez, Manuela, García-Closas, Montserrat, Gaudet, Mia M, George, Angela, Grip, Mervi, Guénel, Pascal, Harrington, Patricia A, Hiller, Louise, Hooning, Maartje J, Hopper, John L, Howell, Anthony, Huang, Chiun-Sheng, Huang, Guanmengqian, Hunter, David J, Jakubowska, Anna, Kaaks, Rudolf, Kapoor, Pooja Middha, Kitahara, Cari M, Lejbkowicz, Flavio, Lindblom, Annika, Lubiński, Jan, Mannermaa, Arto, Maurer, Tabea, Mavroudis, Dimitrios, Meindl, Alfons, Mulligan, Anna Marie, Neuhausen, Susan L, Newman, William G, Olshan, Andrew F, Olson, Janet E, Olsson, Håkan, Petridis, Christos, Prentice, Ross L, Punie, Kevin, Ramachandran, Dhanya, Rennert, Gad, Romero, Atocha, Sachchithananthan, Mythily, Sawyer, Elinor J, Schmutzler, Rita K, Scott, Christopher, Simard, Jacques, Sohn, Christof, Southey, Melissa C, Tamimi, Rulla M, Tapper, William J, Teixeira, Manuel R, Terry, Mary Beth, Thorne, Heather, Tollenaar, Rob A E M, Troester, Melissa A, Truong, Thérèse, Vachon, Celine M, Wang, Qin, Winqvist, Robert, Wolk, Alicja, Yang, Xiaohong R, Ziogas, Argyrios, Pharoah, Paul D P, Chenevix-Trench, Georgia, Bader, Gary D, Dörk, Thilo, Canisius, Sander, Schmidt, Marjanka K
Published in Nature communications

Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations

by Thomas, Minta, Su, Yu-Ru, Rosenthal, Elisabeth A, Timofeeva, Maria N, Chen, Zhishan, Fernandez-Rozadilla, Ceres, Law, Philip J, Carreras-Torres, Robert, Diez-Obrero, Virginia, van Duijnhoven, Franzel J B, Shin, Aesun, Wolk, Alicja, Phipps, Amanda I, Burnett-Hartman, Andrea, Gsur, Andrea, Zauber, Ann G, Wu, Anna H, Lindblom, Annika, Um, Caroline Y, Tangen, Catherine M, Gignoux, Chris, Newton, Christina, Haiman, Christopher A, Qu, Conghui, Buchanan, Daniel D, Crosslin, David R, Conti, David V, Kim, Dong-Hyun, Hauser, Elizabeth, Schumacher, Fredrick R, Rennert, Gad, Giles, Graham G, Hampel, Heather, Brenner, Hermann, Oze, Isao, Schneider, Jennifer L, Chang-Claude, Jenny, Kim, Jeongseon, Zheng, Jiayin, Hampe, Jochen, Palmer, Julie R, Matsuo, Keitaro, Matsuda, Koichi, Li, Li, Le Marchand, Loic, Bujanda, Luis, Matejcic, Marco, Jenkins, Mark A, Wang, Meilin, Hoffmeister, Michael, Woods, Michael O, Kim, Michelle, Iwasaki, Motoki, Du, Mulong, Udaltsova, Natalia, Vodicka, Pavel, Campbell, Peter T, Newcomb, Polly A, Cai, Qiuyin, Pearlman, Rachel, Pai, Rish K, Schoen, Robert E, Haile, Robert W, Vandenputtelaar, Rosita, Prentice, Ross L, Castellví-Bel, Sergi, Tsugane, Shoichiro, Berndt, Sonja I, Lee, Soo Chin, Brezina, Stefanie, Chanock, Stephen J, Jee, Sun Ha, Kweon, Sun-Seog, Vadaparampil, Susan, Harrison, Tabitha A, Yamaji, Taiki, Vymetalkova, Veronika, Arndt, Volker, Jia, Wei-Hua, Shu, Xiao-Ou, Lin, Yi, Ahn, Yoon-Ok, Stadler, Zsofia K, Van Guelpen, Bethany, Ulrich, Cornelia M, Platz, Elizabeth A, Potter, John D, Li, Christopher I, Meester, Reinier, Figueiredo, Jane C, Casey, Graham, Lansdorp Vogelaar, Iris, Dunlop, Malcolm G, Hayes, Richard B, Pharoah, Paul D P, Houlston, Richard S, Tomlinson, Ian P, Zheng, Wei, Corley, Douglas A, Peters, Ulrike
Published in Nature communications

Identifying colorectal cancer caused by biallelic MUTYH pathogenic variants using tumor mutational signatures

by Georgeson, Peter, Harrison, Tabitha A, Pope, Bernard J, Zaidi, Syed H, Qu, Conghui, Steinfelder, Robert S, Lin, Yi, Joo, Jihoon E, Mahmood, Khalid, Clendenning, Mark, Walker, Romy, Amitay, Efrat L, Berndt, Sonja I, Brenner, Hermann, Campbell, Peter T, Cao, Yin, Chan, Andrew T, Chang-Claude, Jenny, Doheny, Kimberly F, Drew, David A, Figueiredo, Jane C, French, Amy J, Gallinger, Steven, Giannakis, Marios, Giles, Graham G, Gsur, Andrea, Gunter, Marc J, Hoffmeister, Michael, Hsu, Li, Huang, Wen-Yi, Limburg, Paul, Manson, JoAnn E, Moreno, Victor, Nassir, Rami, Nowak, Jonathan A, Obón-Santacana, Mireia, Ogino, Shuji, Phipps, Amanda I, Potter, John D, Schoen, Robert E, Sun, Wei, Toland, Amanda E, Trinh, Quang M, Ugai, Tomotaka, Macrae, Finlay A, Rosty, Christophe, Hudson, Thomas J, Jenkins, Mark A, Thibodeau, Stephen N, Winship, Ingrid M, Peters, Ulrike, Buchanan, Daniel D
Published in Nature communications

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31

by Permuth-Wey, Jennifer, Shen, Howard C, Tyrer, Jonathan P, Chen, Zhihua, Lin, Hui-Yi, Chen, Y Ann, Ramus, Susan J, Karevan, Rod, Larson, Melissa C, Anton-Culver, Hoda, Armasu, Sebastian M, Bacot, François, Bandera, Elisa V, Barnholtz-Sloan, Jill, Bloom, Greg, Brooks-Wilson, Angela, Brown, Robert, Butzow, Ralf, Cai, Qiuyin, Campbell, Ian, Chenevix-Trench, Georgia, Coetzee, Gerhard A, Cook, Linda S, Couch, Fergus J, Cramer, Daniel W, Cunningham, Julie M, Despierre, Evelyn, Doherty, Jennifer A, du Bois, Andreas, Dürst, Matthias, Easton, Douglas F, Edwards, Robert, Ekici, Arif B, Fenstermacher, David A, Flanagan, James M, Garcia-Closas, Montserrat, Goodman, Marc T, Gore, Martin, Gronwald, Jacek, Halle, Mari K, Harter, Philipp, Hillemanns, Peter, Høgdall, Claus K, Hosono, Satoyo, Jakubowska, Anna, Jensen, Allan, Jim, Heather, Kalli, Kimberly R, Kaye, Stanley B, Kelemen, Linda E, Kikkawa, Fumitaka, Konecny, Gottfried E, Krakstad, Camilla, Kjaer, Susanne Krüger, Kupryjanczyk, Jolanta, Lancaster, Johnathan M, Le, Nhu D, Liang, Dong, Lim, Boon Kiong, Lin, Jie, Lissowska, Jolanta, Lu, Karen H, Matsuo, Keitaro, Moysich, Kirsten B, Ness, Roberta B, Nevanlinna, Heli, Odunsi, Kunle, Orlow, Irene, Pejovic, Tanja, Pike, Malcolm C, Poole, Elizabeth M, Renner, Stefan P, Rodriguez-Rodriguez, Lorna, Rossing, Mary Anne, Rzepecka, Iwona K, Salvesen, Helga B, Severi, Gianluca, Shu, Xiao-Ou, Shvetsov, Yurii B, Song, Honglin, Spiewankiewicz, Beata, Stram, Daniel, Sutphen, Rebecca, Teo, Soo-Hwang, Terry, Kathryn L, Thompson, Pamela J, van Altena, Anne M, Vergote, Ignace, Vierkant, Robert A, Wang-Gohrke, Shan, Palmieri Weber, Rachel, Wik, Elisabeth, Wilkens, Lynne R, Woo, Yin Ling, Ziogas, Argyrios, Phelan, Catherine M, Berchuck, Andrew, Fridley, Brooke L, Pharoah, Paul D P, Sellers, Thomas A
Published in Nature communications

Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A

by Wang, Hansong, Burnett, Terrilea, Kono, Suminori, Haiman, Christopher A, Iwasaki, Motoki, Wilkens, Lynne R, Loo, Lenora W M, Van Den Berg, David, Kolonel, Laurence N, Henderson, Brian E, Keku, Temitope O, Sandler, Robert S, Signorello, Lisa B, Blot, William J, Newcomb, Polly A, Pande, Mala, Amos, Christopher I, West, Dee W, Bézieau, Stéphane, Berndt, Sonja I, Zanke, Brent W, Hsu, Li, Lindor, Noralane M, Haile, Robert W, Hopper, John L, Jenkins, Mark A, Gallinger, Steven, Casey, Graham, Stenzel, Stephanie L, Schumacher, Fredrick R, Peters, Ulrike, Gruber, Stephen B, Tsugane, Shoichiro, Stram, Daniel O, Le Marchand, Loïc
Published in Nature communications

Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer

by Lawrenson, Kate, Kar, Siddhartha, Tyrer, Jonathan, Spindler, Tassja J, Lee, Janet, Chen, Yibu, Karst, Alison, Aben, Katja K H, Anton-Culver, Hoda, Antonenkova, Natalia, Baker, Helen, Bean, Yukie, Berchuck, Andrew, Bisogna, Maria, Bjorge, Line, Brinton, Louise A, Bruinsma, Fiona, Campbell, Ian G, Carty, Karen, Chang-Claude, Jenny, Chen, Anne, Chen, Zhihua, Cook, Linda S, Cramer, Daniel W, Dansonka-Mieszkowska, Agnieszka, Dennis, Joe, Dicks, Ed, Doherty, Jennifer A, Eccles, Diana, Edwards, Robert P, Eilber, Ursula, Ekici, Arif B, Fasching, Peter A, Fridley, Brooke L, Gao, Yu-Tang, Giles, Graham G, Goode, Ellen L, Grownwald, Jacek, Harrington, Patricia, Hasmad, Hanis Nazihah, Hein, Alexander, Heitz, Florian, Hillemanns, Peter, Hogdall, Estrid, Hogdall, Claus, Jakubowska, Anna, James, Paul, Jensen, Allan, Kellar, Melissa, Kelley, Joseph L, Krakstad, Camilla, Kupryjanczyk, Jolanta, Le, Nhu D, Lee, Alice W, Leminen, Arto, Lester, Jenny, Levine, Douglas A, Liang, Dong, Lu, Karen, Lubinski, Jan, Lundvall, Lene, Matsuo, Keitaro, McLaughlin, John R, Nevanlinna, Heli, McNeish, Ian, Modugno, Francesmary, Narod, Steven A, Ness, Roberta B, Olson, Sara H, Pearce, Celeste L, Pejovic, Tanja, Permuth-Wey, Jennifer, Phelan, Catherine M, Pike, Malcolm C, Poole, Elizabeth M, Rosen, Barry, Rossing, Mary Anne, Rothstein, Joseph H, Rudolph, Anja, Runnebaum, Ingo B, Rzepecka, Iwona K, Sellers, Thomas A, Shvetsov, Yurii B, Sieh, Weiva, Sucheston, Lara, Terry, Kathryn L, Thompson, Pamela J, Timorek, Agnieszka, Tsai, Ya-Yu, Tworoger, Shelley S, Van Nieuwenhuysen, Els, Wang-Gohrke, Shan, Walsh, Christine, Wentzensen, Nicolas, Whittemore, Alice S, Woo, Yin-Ling, Yang, Hannah, Zheng, Wei, Ziogas, Argyrios, Freedman, Matthew L
Published in Nature communications