Discovery of Further Pyrrolidine trans-Lactams as Inhibitors of Human Neutrophil Elastase (HNE) with Potential as Development Candidates and the Crystal Structure of HNE Complexed... by Macdonald, Simon J. F, Dowle, Michael D, Harrison, Lee A, Clarke, Geoffrey D. E, Inglis, Graham G. A, Johnson, Martin R, Shah, Pritom, Smith, Robin A, Amour, Augustin, Fleetwood, Gill, Humphreys, Davina C, Molloy, Christopher R, Dixon, Mary, Godward, Rosalind E, Wonacott, Alan J, Singh, Onkar M. P, Hodgson, Simon T, Hardy, George W

Get full text

A Flexible, Practical, and Stereoselective Synthesis of Enantiomerically Pure trans-5-Oxohexahydropyrrolo[3,2-b]pyrroles (Pyrrolidine-trans-lactams), a New Class of Serine Protease... by Macdonald, Simon J. F, Clarke, Geoffrey D. E, Dowle, Michael D, Harrison, Lee A, Hodgson, Simon T, Inglis, Graham G. A, Johnson, Martin R, Shah, Prit, Upton, Richard J, Walls, Steven B

Get full text

Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells by Clarke, Michael F, Dick, John E, Dirks, Peter B, Eaves, Connie J, Jamieson, Catriona H M, Jones, D Leanne, Visvader, Jane, Weissman, Irving L, Wahl, Geoffrey M

Get full text

Alignment of the stellar spin with the orbits of a three-planet system by SANCHIS-OJEDA, Roberto, FABRYCKY, Daniel C, JENKINS, Jon M, KOCH, David, LISSAUER, Jack J, MARY, Geoffrey W, MULLALLY, Fergal, RAGOZZINE, Darin, SEADER, Shawn E, STILL, Martin, THOMPSON, Susan E, WINN, Joshua N, BARCLAY, Thomas, CLARKE, Bruce D, FORD, Eric B, FORTNEY, Jonathan J, GEARY, John C, HOLMAN, Matthew J, HOWARD, Andrew W

Get full text

Patient-derived xenograft (PDX) models in basic and translational breast cancer research by Dobrolecki, Lacey E., Airhart, Susie D., Alferez, Denis G., Aparicio, Samuel, Behbod, Fariba, Bentires-Alj, Mohamed, Brisken, Cathrin, Bult, Carol J., Cai, Shirong, Clarke, Robert B., Dowst, Heidi, Ellis, Matthew J., Gonzalez-Suarez, Eva, Iggo, Richard D., Kabos, Peter, Li, Shunqiang, Lindeman, Geoffrey J., Marangoni, Elisabetta, McCoy, Aaron, Meric-Bernstam, Funda, Piwnica-Worms, Helen, Poupon, Marie-France, Reis-Filho, Jorge, Sartorius, Carol A., Scabia, Valentina, Sflomos, George, Tu, Yizheng, Vaillant, François, Visvader, Jane E., Welm, Alana, Wicha, Max S., Lewis, Michael T.

Get full text

Small Multifunctional Nanoclusters (Nanoroses) for Targeted Cellular Imaging and Therapy by Ma, Li Leo, Feldman, Marc D, Tam, Jasmine M, Paranjape, Amit S, Cheruku, Kiran K, Larson, Timothy A, Tam, Justina O, Ingram, Davis R, Paramita, Vidia, Villard, Joseph W, Jenkins, James T, Wang, Tianyi, Clarke, Geoffrey D, Asmis, Reto, Sokolov, Konstantin, Chandrasekar, Bysani, Milner, Thomas E, Johnston, Keith P

Get full text

Fitness factor genes conserved within the multi-species core genome of Gram-negative Enterobacterales species contribute to bacteremia pathogenesis by Mobley, Harry L. T, Anderson, Mark T, Moricz, Bridget S, Severin, Geoffrey B, Holmes, Caitlyn L, Ottosen, Elizabeth N, Eichler, Tad, Gupta, Surbhi, Paudel, Santosh, Sinha, Ritam, Mason, Sophia, Himpsl, Stephanie D, Brown, Aric N, Gaca, Margaret, Kiser, Christina M, Clarke, Thomas H, Fouts, Derrick E, DiRita, Victor J, Bachman, Michael A

Get full text

Assessment of tumor hypoxia and perfusion in recurrent glioblastoma following bevacizumab failure using MRI and 18F-FMISO PET by Huang, Shiliang, Michalek, Joel E., Reardon, David A., Wen, Patrick Y., Floyd, John R., Fox, Peter T., Clarke, Geoffrey D., Jerabek, Paul A., Schmainda, Kathleen M., Muzi, Mark, Hyun, Hyewon, Lee, Eudocia Quant, Brenner, Andrew J.

Get full text

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris by Schaum, Nicholas, Karkanias, Jim, Neff, Norma F., May, Andrew P., Quake, Stephen R., Wyss-Coray, Tony, Darmanis, Spyros, Batson, Joshua, Botvinnik, Olga, Chen, Michelle B., Chen, Steven, Green, Foad, Jones, Robert, Maynard, Ashley, Penland, Lolita, Pisco, Angela Oliveira, Sit, Rene V., Stanley, Geoffrey M., Webber, James T., Zanini, Fabio, Baghel, Ankit S, Bakerman, Isaac, Bansal, Ishita, Berdnik, Daniela, Bilen, Biter, Brownfield, Douglas, Cain, Corey, Cho, Min, Cirolia, Giana, Conley, Stephanie D., Darmanis, Spyros, Demers, Aaron, Demir, Kubilay, de Morree, Antoine, Divita, Tessa, du Bois, Haley, Dulgeroff, Laughing Bear Torrez, Ebadi, Hamid, Espinoza, F. Hernán, Fish, Matt, Gan, Qiang, George, Benson M., Gillich, Astrid, Genetiano, Geraldine, Gu, Xueying, Gulati, Gunsagar S., Hang, Yan, Hosseinzadeh, Shayan, Huang, Albin, Iram, Tal, Isobe, Taichi, Ives, Feather, Kao, Kevin S., Karnam, Guruswamy, Kershner, Aaron M., Kiss, Bernhard M., Kong, William, Kumar, Maya E., Lam, Jonathan, Lee, Davis P., Lee, Song E., Li, Guang, Li, Qingyun, Liu, Ling, Lo, Annie, Lu, Wan-Jin, Manjunath, Anoop, May, Kaia L., May, Oliver L., McKay, Marina, Metzger, Ross J., Mignardi, Marco, Min, Dullei, Nabhan, Ahmad N., Ng, Katharine M., Noh, Joseph, Patkar, Rasika, Peng, Weng Chuan, Puccinelli, Robert, Rulifson, Eric J., Sikandar, Shaheen S., Sinha, Rahul, Szade, Krzysztof, Tan, Weilun, Tato, Cristina, Tellez, Krissie, Travaglini, Kyle J., Tropini, Carolina, Waldburger, Lucas, van Weele, Linda J., Wosczyna, Michael N., Xiang, Jinyi, Xue, Soso, Youngyunpipatkul, Justin, Zardeneta, Macy E., Zhang, Fan, Zhou, Lu, oungyunpipatkul, Justin Y, Castro, Paola, Croote, Derek

Get full text

Distinct nuclear receptor expression in stroma adjacent to breast tumors by Knower, Kevin C., Chand, Ashwini L., Eriksson, Natalie, Takagi, Kiyoshi, Miki, Yasuhiro, Sasano, Hironobu, Visvader, Jane E., Lindeman, Geoffrey J., Funder, John W., Fuller, Peter J., Simpson, Evan R., Tilley, Wayne D., Leedman, Peter J., Graham, J. Dinny, Muscat, George E. O., Clarke, Christine L., Clyne, Colin D.

Get full text

The genomes of two key bumblebee species with primitive eusocial organization by Sadd, Ben M, de Graaf, Dirk C, Elsik, Christine G, Gadau, Jürgen, Hasselmann, Martin, Stolle, Eckart, Waterhouse, Robert M, Bornberg-Bauer, Erich, Klasberg, Steffen, Bennett, Anna K, Guigó, Roderic, Hoff, Katharina, Mariotti, Marco, Santesmasses, Didac, Amdam, Gro V, Beckers, Matthew, Beye, Martin, Bitondi, Márcia M G, Blaxter, Mark L, Bourke, Andrew F G, Brown, Mark J F, Buechel, Severine D, Cameron, Rossanah, Cappelle, Kaat, Carolan, James C, Christiaens, Olivier, Ciborowski, Kate L, Collins, David H, Cridge, Andrew G, Dreier, Stephanie, du Plessis, Louis, Evans, Jay, Flores, Kevin, Freitas, Flávia C P, Fuchikawa, Taro, Hartfelder, Klaus, Hauser, Frank, Helbing, Sophie, Jermiin, Lars S, Johnson, Claire E, Johnson, Reed M, Jones, Andrew K, Kidner, Jonathan H, Koch, Vasco, Kraus, F Bernhard, Lattorff, H Michael G, Mallon, Eamonn B, Antonio, David S Marco, Marxer, Monika, Moritz, Robin F A, Nissen, Inga, Niu, Jinzhi, Nunes, Francis M F, Oakeshott, John G, Otte, Marianne, Rossié, Nina, Rueppell, Olav, Santos, Carolina G, Schmid-Hempel, Regula, Schulte, Christina, Simões, Zilá L P, Soares, Michelle P M, Swevers, Luc, Winnebeck, Eva C, Wolschin, Florian, Yu, Na, Zdobnov, Evgeny M, Coyle, Marcus, Francisco, Liezl, Hernandez, Alvaro G, Holder, Michael, Hudson, Matthew E, Jackson, LaRonda, Jayaseelan, Joy, Joshi, Vandita, Kovar, Christie, Lee, Sandra L, Mata, Robert, Mathew, Tittu, Ngo, Robin, Pham, Christopher, Saada, Nehad, Santibanez, Jireh, Thornton, Rebecca, Venkat, Aarti, Wu, Yuan-Qing, Debyser, Griet, Devreese, Bart, Asher, Claire, Chipman, Ariel D, Chittka, Lars, Fouks, Bertrand, Liu, Jisheng, Puiu, Daniela, Salzberg, Steven L, Scherer, Steven E, Muzny, Donna M, Gibbs, Richard A, Schmid-Hempel, Paul, Worley, Kim C

Get full text

CD83 is a new potential biomarker and therapeutic target for Hodgkin lymphoma by Li, Ziduo, Ju, Xinsheng, Lee, Kenneth, Clarke, Candice, Hsu, Jennifer L, Abadir, Edward, Bryant, Christian E, Pears, Suzanne, Sunderland, Neroli, Heffernan, Scott, Hennessy, Annemarie, Lo, Tsun-Ho, Pietersz, Geoffrey A, Kupresanin, Fiona, Fromm, Phillip D, Silveira, Pablo A, Tsonis, Con, Cooper, Wendy A, Cunningham, Ilona, Brown, Christina, Clark, Georgina J, Hart, Derek N J

Get full text

Rapid solidification growth mode transitions in Al-Si alloys by dynamic transmission electron microscopy by Roehling, John D., Coughlin, Daniel R., Gibbs, John W., Baldwin, J. Kevin, Mertens, James C.E., Campbell, Geoffrey H., Clarke, Amy J., McKeown, Joseph T.

Get full text

Prospective comparison of restriction spectrum imaging and non-invasive biomarkers to predict upgrading on active surveillance prostate biopsy by Eng, Stefan E, Basasie, Benjamin, Lam, Alfonso, John Semmes, O, Troyer, Dean A, Clarke, Geoffrey D, Sunnapwar, Abhijit G, Leach, Robin J, Johnson-Pais, Teresa L, Sokoll, Lori J, Chan, Daniel W, Tosoian, Jeffrey J, Siddiqui, Javed, Chinnaiyan, Arul M, Thompson, Jr, Ian M, Boutros, Paul C, Liss, Michael A

Get full text

Kepler Planet-Detection Mission: Introduction and First Results by Borucki, William J, Koch, David, Basri, Gibor, Batalha, Natalie, Brown, Timothy, Caldwell, Douglas, Caldwell, John, Christensen-Dalsgaard, Jørgen, Cochran, William D, DeVore, Edna, Dunham, Edward W, Dupree, Andrea K, Gautier, Thomas N. III, Geary, John C, Gilliland, Ronald, Gould, Alan, Howell, Steve B, Jenkins, Jon M, Kondo, Yoji, Latham, David W, Marcy, Geoffrey W, Meibom, Søren, Kjeldsen, Hans, Lissauer, Jack J, Monet, David G, Morrison, David, Sasselov, Dimitar, Tarter, Jill, Boss, Alan, Brownlee, Don, Owen, Toby, Buzasi, Derek, Charbonneau, David, Doyle, Laurance, Fortney, Jonathan, Ford, Eric B, Holman, Matthew J, Seager, Sara, Steffen, Jason H, Welsh, William F, Rowe, Jason, Anderson, Howard, Buchhave, Lars, Ciardi, David, Walkowicz, Lucianne, Sherry, William, Horch, Elliott, Isaacson, Howard, Everett, Mark E, Fischer, Debra, Torres, Guillermo, Johnson, John Asher, Endl, Michael, MacQueen, Phillip, Bryson, Stephen T, Dotson, Jessie, Haas, Michael, Kolodziejczak, Jeffrey, Van Cleve, Jeffrey, Chandrasekaran, Hema, Twicken, Joseph D, Quintana, Elisa V, Clarke, Bruce D, Allen, Christopher, Li, Jie, Wu, Haley, Tenenbaum, Peter, Verner, Ekaterina, Bruhweiler, Frederick, Barnes, Jason, Prsa, Andrej

Get full text

Influence of the Human Lipidome on Epicardial Fat Volume in Mexican American Individuals by Leandro, Ana Cristina, Michael, Laura F, Almeida, Marcio, Kuokkanen, Mikko, Huynh, Kevin, Giles, Corey, Duong, Thy, Diego, Vincent P, Duggirala, Ravindranath, Clarke, Geoffrey D, Blangero, John, Meikle, Peter J, Curran, Joanne E

Get full text

Molecular and biologic analysis of histone deacetylase inhibitors with diverse specificities by Newbold, Andrea, Matthews, Geoffrey M, Bots, Michael, Cluse, Leonie A, Clarke, Christopher J P, Banks, Kellie-Marie, Cullinane, Carleen, Bolden, Jessica E, Christiansen, Ailsa J, Dickins, Ross A, Miccolo, Claudia, Chiocca, Susanna, Kral, Astrid M, Ozerova, Nicole D, Miller, Thomas A, Methot, Joey L, Richon, Victoria M, Secrist, J Paul, Minucci, Saverio, Johnstone, Ricky W

Get full text

Molecular Subgroup of Primary Prostate Cancer Presenting with Metastatic Biology by Walker, Steven M, Knight, Laura A, McCavigan, Andrena M, Logan, Gemma E, Berge, Viktor, Sherif, Amir, Pandha, Hardev, Warren, Anne Y, Davidson, Catherine, Uprichard, Adam, Blayney, Jaine K, Price, Bethanie, Jellema, Gera L, Steele, Christopher J, Svindland, Aud, McDade, Simon S, Eden, Christopher G, Foster, Chris, Mills, Ian G, Neal, David E, Mason, Malcolm D, Kay, Elaine W, Waugh, David J, Harkin, D. Paul, Watson, R. William, Clarke, Noel W, Kennedy, Richard D

Get full text

TRANSIT TIMING OBSERVATIONS FROM KEPLER. II. CONFIRMATION OF TWO MULTIPLANET SYSTEMS VIA A NON-PARAMETRIC CORRELATION ANALYSIS by FORD, Eric B, FABRYCKY, Daniel C, ROWE, Jason F, WELSH, William F, ALLEN, Christopher, BATALHA, Natalie M, BORUCKI, William J, BRYSON, Stephen T, BUCHHAVE, Laps A, BURKE, Christopher J, CALDWELL, Douglas A, CHARBONNEAU, David, STEFFEN, Jason H, CLARKE, Bruce D, COCHRAN, William D, DESERT, Jean-Michel, ENDL, Michael, EVERETT, Mark E, FISCHER, Debra A, GAUTIER, Thomas N, GILLILAND, Ron L, JENKINS, Jon M, HAAS, Michael R, CARTER, Joshua A, HORCH, Elliott, HOWELL, Steve B, IBRAHIM, Khadeejah A, ISAACSON, Howard, KOCH, David G, LATHAM, David W, JIE LI, LUCAS, Philip, MACQUEEN, Phillip J, MARCY, Geoffrey W, FRESSIN, Francois, MCCAULLFF, Sean, MULLALLY, Fergal R, QUINN, Samuel N, QUINTANA, Elisa, SHPORER, Avi, STILL, Martin, TENENBAUM, Peter, THOMPSON, Susan E, TORRES, Guillermo, TWICKEN, Joseph D, HOLMAN, Matthew J, WOHLER, Bill, LISSAUER, Jack J, MOORHEAD, Althea V, MOREHEAD, Robert C, RAGOZZINE, Darin

Get full text

Detecting the Change in Total Circulatory Flow with a Wireless, Wearable Doppler Ultrasound Patch: A Pilot Study by Munding, Chelsea E, Kenny, Jon-Émile S, Yang, Zhen, Clarke, Geoffrey, Elfarnawany, Mai, Eibl, Andrew M, Eibl, Joseph K, Nalla, Bhanu, Atoui, Rony

Get full text