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XPO1 blockade with KPT-330 promotes apoptosis in cutaneous T-cell lymphoma by activating the p53-p21 and p27 pathways
by
Chakravarti, Nitin
,
Boles, Amy
,
Burzinski, Rachel
,
Sindaco, Paola
,
Isabelle, Colleen
,
McConnell, Kathleen
,
Mishra, Anjali
,
Porcu, Pierluigi
Published in
Scientific reports
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Inhibition of XPO1 with Selinexor (KPT-330) triggers apoptosis in cutaneous T-cell lymphoma (CTCL) by activating the p53-p21 and p27 pathways
by
Chakravarti, Nitin
,
Boles, Amy
,
Sindaco, Paola
,
Isabelle, Colleen
,
McConnell, Kathleen
,
Burzinski, Rachel
,
Mishra, Anjali
,
Porcu, Pierluigi
Published in
European journal of cancer (1990)
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European Journal Of Cancer
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Scientific Reports
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Animals
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Apoptosis
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Apoptosis - Drug Effects
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B-Cell Lymphoma
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Bioluminescence
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Cell Cycle
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Cell Line, Tumor
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Cell Proliferation
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Cell Proliferation - Drug Effects
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Cyclin-Dependent Kinase Inhibitor P21
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Cyclin-Dependent Kinase Inhibitor P21 - Genetics
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Cyclin-Dependent Kinase Inhibitor P21 - Metabolism
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Cyclin-Dependent Kinase Inhibitor P27
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Cyclin-Dependent Kinase Inhibitor P27 - Genetics
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Cyclin-Dependent Kinase Inhibitor P27 - Metabolism
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Exportin 1 Protein
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Gene Expression Regulation, Neoplastic - Drug Effects
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Hodgkin's Lymphoma
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Humans
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Hydrazines - Pharmacology
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