ORAL ABSTRACTS (2)EP & Ablation19CARDIAC ABLATION PATIENT REPORTED OUTCOMES MEASURES (PROMS): ANALYSIS OF POST-ABLATION AND 1 YEAR FOLLOW-UP DATA20INTENTIONAL CORONARY VEIN EXIT AN... by Evans, J.M., Silberbauer, John, Glover, B., McLellan, A.J.A., Panikker, S., Sieniewicz, B.J., Burg, M.R., Behar, J.M., Burke, M.C., Withers, K.L., Lencioni, M., Carolan-Rees, G., Wood, K.A., Patrick, H., Griffith, M., Gomes, J., Kirubakaran, S., McCready, J., Michael, K., Hashemi, J., Gupta, D., Akl, S., Redfearn, D., Lim, E., Butcher, C., Khan, H., Mantziari, L., Hussain, W., Jones, D., Clague, J.R., Ernst, S., Markides, V., Wong, T., Ezzat, V.A., Schilling, R.J., Lowe, M.D., Whitaker, J., Virmani, R., Kutys, R., Fastl, T., Haldar, S., O'Neill, M., Corado, C., Nicol, E., Foran, J.P., Niederer, S., Sohal, M., Jais, P., Derval, N., Spragg, D., Van Gelder, B., Bracke, F., Steendijk, P., Rinaldi, C.A., Chooneea, B., Gajendragadkar, P.R., Ahsan, S., Begley, D.A., Dhinoja, M., Earley, M.J., Finlay, M., Grace, A.A., Hunter, R.J., Lambiase, P.D., Rowland, E., Segal, O.R., Sporton, S., Virdee, M.S., Chow, A., Apap Bologna, R., Camilleri, W., Sammut, M.A., Aquilina, O., Barra, S., Falconer, D., Duehmke, R., Rehal, O., Ioannou, A., Lowe, M., Lambiase, P., Agarwal, S., Chow, A.W., Toth, D., Mountney, P., Reiml, S., Panayioutu, M., Fahn, B., Patel, N.R., Claridge, S., Jackson, T., Adhya, S., Sieniwicz, B., Razavi, R., Rhode, K., Tjong, F.V.Y., Brouwer, T.F., Koop, B., Soltis, B., Shuros, A., Knops, R.E.

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ATM: Translating the DNA Damage Response to Adaptive Immunity by Weitering, Thomas J., Takada, Sanami, Weemaes, Corry M.R., van Schouwenburg, Pauline A., van der Burg, Mirjam

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Antibody deficiency in patients with ataxia telangiectasia is caused by disturbed B- and T-cell homeostasis and reduced immune repertoire diversity by Driessen, Gertjan J., MD, IJspeert, Hanna, MSc, Weemaes, Corry M.R., MD, PhD, Haraldsson, Ásgeir, MD, PhD, Trip, Margreet, MD, Warris, Adilia, MD, PhD, van der Flier, Michiel, MD, PhD, Wulffraat, Nico, MD, PhD, Verhagen, Mijke M.M., MD, PhD, Taylor, Malcolm A., MD, PhD, van Zelm, Menno C., PhD, van Dongen, Jacques J.M., MD, PhD, van Deuren, Marcel, MD, PhD, van der Burg, Mirjam, PhD

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Early Diagnosis of Ataxia Telangiectasia Through Newborn Screening for SCID: a Case Report Highlighting the Dilemma of Pre-emptive HSCT by Weitering, T. J., Willemsen, M. A. A. P., Taylor, A. M. R., Weemaes, C. M. R., van der Burg, M., Berghuis, Dagmar

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Causative mechanisms and clinical impact of immunoglobulin deficiencies in ataxia telangiectasia by Takada, Sanami, Weitering, Thomas J., van Os, Nienke J.H., Du, Likun, Pico-Knijnenburg, Ingrid, Kuipers, Thomas B., Mei, Hailiang, Salzer, Elisabeth, Willemsen, Michèl A.A.P., Weemaes, Corry M.R., Pan-Hammarstrom, Qiang, van der Burg, Mirjam

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Early diagnosis of ataxia telangiectasia in the neonatal phase: a parents’ perspective by Schoenaker, M. H. D., Blom, M., de Vries, M. C., Weemaes, C. M. R., van der Burg, M., Willemsen, M. A. A. P.

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Predictive Biomarkers for Outcomes of Immune Checkpoint Inhibitors (ICIs) in Melanoma: A Systematic Review by Baltussen, Joosje C, Welters, Marij J P, Verdegaal, Elizabeth M E, Kapiteijn, Ellen, Schrader, Anne M R, Slingerland, Marije, Liefers, Gerrit-Jan, van der Burg, Sjoerd H, Portielje, Johanneke E A, de Glas, Nienke A

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Outcomes in Octogenarians and the Effect of Comorbidities After Intact Abdominal Aortic Aneurysm Repair in the Netherlands: A Nationwide Cohort Study by de Bruin, Jorg L., Bendermacher, B.L., Blankensteijn, J.D., van der Bogt, K.E., Bosma, J., Brehm, V., de Bruijn, M.T., Castenmiller, P.H., Cazander, G., Dawson, I., Dijkstra, M.L., Drouven, J.W., Elsman, B.H., van der Elst, A., van Eps, R.G., Frans, F.A., Geelkerken, R.H., van Gent, W.B., de Haan, E.F., Hazenberg, C.E., Hendriks, J.M., Hinnen, J.W., Hissink, R.J., den Hoed, P.T., Hoencamp, R., Hogendoorn, W., Hopmans, C.J., Idu, M.M., Jacobs, M.J., Jiang, H.H., de Jong, S.C., Jongkind, V., Kapma, M.R., Kievit, J.K., Klemm, P.L., Klinkert, P., Koelemaij, M.J., Koning, G.G., Kropman, R.H., Kruse, R.R., van der Laan, L., van Lammeren, G.W., Lauret, G.J., Leenders, B.J., Legemate, D.A., Lemson, M.S., Loos, M.J., Mahmoud, D.E., Mattens, E.C., Menting, T.P., Minnee, R.C., van de Mortel, R.H., Nagesser, S.K., Naves, C.C., Nevenzel-Putters, A.M., Nieuwenhuis, D.H., Nieuwenhuizen, J., van Nieuwenhuizen, R.C., Noyez, V.J., Oranen, B.I., Poyck, P.P., van Rijn, M.J., de Roo, R.A., Rouwet, E.V., van Sambeek, M.R., Samyn, M.G., van Schaik, J., van Schaik, P.M., Schepers, A., Schlosser, F.J., te Slaa, A., Smeets, R.R., de Smet, A.A., van der Steenhoven, T.J., van Sterkenburg, S.M., Stokmans, R.A., Teraa, M., Testroote, M.J., Tha-In, T., The, R.M., Vaes, R.H., Vafi, A.A., Vahl, A.C., Veger, H.T., Veldman, M.G., Vermeulen, C.F., Vierhout, B.P., van der Vliet, J.A., Vriens, P.W., Wallis de Vries, B.M., Warlé, M.C., Welten, G.M., Wiersema, A.M., Wikkeling, O.R., Wille, J., Willems, M.C., Willigendael, E.M., Wilschut, E.D., Wittens, C.H., Yazar, O.

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Normal Numbers of Stem Cell Memory T Cells Despite Strongly Reduced Naive T Cells Support Intact Memory T Cell Compartment in Ataxia Telangiectasia by Weitering, Thomas J., Melsen, Janine E., van Ostaijen-ten Dam, Monique M., Weemaes, Corry M. R., Schilham, Marco W., van der Burg, Mirjam

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Dilemma of Reporting Incidental Findings in Newborn Screening Programs for SCID: Parents' Perspective on Ataxia Telangiectasia by Blom, Maartje, Schoenaker, Michiel H D, Hulst, Myrthe, de Vries, Martine C, Weemaes, Corry M R, Willemsen, Michèl A A P, Henneman, Lidewij, van der Burg, Mirjam

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Practical Guide to Measuring Wetland Carbon Pools and Fluxes by Bansal, Sheel, Creed, Irena F., Tangen, Brian A., Bridgham, Scott D., Desai, Ankur R., Krauss, Ken W., Neubauer, Scott C., Noe, Gregory B., Rosenberry, Donald O., Trettin, Carl, Wickland, Kimberly P., Allen, Scott T., Arias-Ortiz, Ariane, Armitage, Anna R., Baldocchi, Dennis, Banerjee, Kakoli, Bastviken, David, Berg, Peter, Bogard, Matthew J., Chow, Alex T., Conner, William H., Craft, Christopher, Creamer, Courtney, DelSontro, Tonya, Duberstein, Jamie A., Eagle, Meagan, Fennessy, M. Siobhan, Finkelstein, Sarah A., Göckede, Mathias, Grunwald, Sabine, Halabisky, Meghan, Herbert, Ellen, Jahangir, Mohammad M. R., Johnson, Olivia F., Jones, Miriam C., Kelleway, Jeffrey J., Knox, Sara, Kroeger, Kevin D., Kuehn, Kevin A., Lobb, David, Loder, Amanda L., Ma, Shizhou, Maher, Damien T., McNicol, Gavin, Meier, Jacob, Middleton, Beth A., Mills, Christopher, Mistry, Purbasha, Mitra, Abhijit, Mobilian, Courtney, Nahlik, Amanda M., Newman, Sue, O’Connell, Jessica L., Oikawa, Patty, van der Burg, Max Post, Schutte, Charles A., Song, Changchun, Stagg, Camille L., Turner, Jessica, Vargas, Rodrigo, Waldrop, Mark P., Wallin, Marcus B., Wang, Zhaohui Aleck, Ward, Eric J., Willard, Debra A., Yarwood, Stephanie, Zhu, Xiaoyan

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Nationwide study of the treatment of mycotic abdominal aortic aneurysms comparing open and endovascular repair in The Netherlands by Dang, Quan, Statius van Eps, Randolph G., Wever, Jan J., Van den Akker, P.J., Akkersdijk, G.P., Baal, J.G., Balm, R., Bender, M.H., Bendermacher, B.L., van den Berg, M., Beuk, R.J., Bleker, R.J., Bodegom, M.E., Boll, A.P., Booster, M.H., Borger van der Burg, B.L., de Borst, G.J., Breek, J.C., Brehm, V., Brinckman, M.J., Brom, H.L., de Bruijn, M.T., Brummel, P., Buijk, S.E., Buscher, H.C., den Butter, G., Castenmiller, P.H., Cazander, G., Coveliers, H.M., Derom, A.F., Dinkelman, M.K., Elsman, B.H., van der Elst, A., van Eps, R.G., Faber, M.J., Glade, G.J., de Groot, H.G., van den Haak, R.F., Hajer, G.F., Hedeman Joosten, P.P., Heyligers, J.M., Ho, G.H., Hoffmann, W.H., Hollander, E.J., Idu, M.M., Jacobs, M.J., Jongkind, V., Kapma, M.R., Koedam, N.A., Koning, G.G., Koning, O.H., Krasznai, A.G., Leijdekkers, V.J., Lijkwan, M.A., Liqui Lung, P.F., Meerwaldt, R., Mees, B.M., Metz, R., Montauban van Swijndregt, Y.C., Morak, M.J., Nagesser, S.K., van Nieuwenhuizen, R.C., van Petersen, A.S., Pierie, M.E., Ploeg, A.J., Ponfoort, E.D., ten Raa, S., van Sambeek, M.R., Samyn, M.G., van ’t Sant, H.P., Schepers, A., Schlejen, P.M., Schlosser, F.J., Schouten, O., Schreve, M.A., Schurink, G.W., Sikkink, C.J., Smeets, H.J., Smeets, L., de Smet, A.A., Stigter, H., Strating, R.P., Thijsse, W.J., van Tongeren, R.B., Tordoir, J.H., Tournoij, E., Veger, H.T., Vlijmen - van Keulen, C.J., Voesten, H.G., Vos, A.W., de Vos, B., Vriens, P.W., de Vries, M., van Walraven, L.A., van Weel, V., Welten, R.J., Wever, J.J., Wittens, C.H., Wolf-de Jonge, I.C., Yazar, O.

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P12 HEALTH-RELATED QUALITY OF LIFE IN FRAIL AND INTERMEDIATE-FIT PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA TREATED WITH DOSE-ADJUSTED MELPHALAN-PREDNISONE-BORTEZOMIB (MPV) by Seefat, M.R., Stege, C.A.M., Timmers, G.J., Levin, M.D., Hoogendoorn, M., Ypma, P.F., Nijhof, I.S., Velders, G.A., Strobbe, L., Durdu-Rayman, N., Westerman, M., Davidis-van Schoonhoven, M.A., van Kampen, R.J.W., Beeker, A., Koster, A., Dijk, A.C., van de Donk, N.W.C.J., van der Spek, E., Leys, M.B.L., Silbermann, M.H., Groen, K., van der Burg-de Graauw, N.C.H.P., Sinnige, H.A.M., van der Hem, K.G., Levenga, T.H., Bilgin, Y.M., Sonneveld, P., Klein, S.K., Nasserinejad, K., Blommestein, H.M., Cucchi, D.G.J., Lissenberg-Witte, B.I., Zweegman, S.

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A Composite Measure for Quality of Care in Patients with Symptomatic Carotid Stenosis Using Textbook Outcome by Kuhrij, Laurien S., Vahl, Anco C., Willems, Martine C.M., Elshof, Jan W., de Borst, Gert J., Akkersdijk, G.J., Balm, R., Botman, J.M., Brehm, V., Brummel, P., van Brussel, J.P., Buijs, M.A., Cancrinus, E., Castenmiller, P.H., Daemen, J.H., Dawson, I., Dijkstra, M.L., Dirven, M., Elsman, B.H., van der Elst, A., Fung Kon Jin, P.H., van Gent, W.B., Groenendijk, R.P., Hamming, J.F., Hedeman Joosten, P.P., Helleman, J.N., Ho, G.H., den Hoed, P.T., Hoksbergen, A.W., Hommes, M., Idu, M.M., Jiang, H.H., Jongkind, V., Kapma, M.R., Kolkert, J.L., Koning, G.G., Konings, R., Kruse, R.R., van der Laan, M.J., Lardenoye, J.H., Leenders, B.J., Lind, R.C., Loos, M.J., Loubert, M.C., Mahmoud, D.E., Manshanden, C.G., Mattens, E.C., von Meijenfeldt, G.C., Menting, T.P., Minnee, R.C., van de Mortel, R.H., Nevenzel-Putters, A.M., Nieuwenhuis, D.H., van Nieuwenhuizen, R.C., Nio, D., Oomen, A.P., Palamba, H.W., Peppelenbosch, A.G., Ploeg, A.J., Ponfoort, E.D., ten Raa, S., Raymakers, J.T., Reijnen, M.M., van Rijn, M.J., de Roo, R.A., van Sambeek, M.R., van ’t Sant, H.P., van Schaik, J., van Schaik, P.M., Scharn, D.M., Scholtes, V.P., Schreve, M.A., Sikkink, C.J., Smeets, L., Smit, P.C., Snoeijs, M.G., Speijers, M.J., van der Steenhoven, T.J., van Sterkenburg, S.M., Stigter, D.A., Stokmans, R.A., Sybrandy, J.E., Teijink, J.A., Telgenkamp, B.J., Tha-In, T., The, R.M., Thijsse, W.J., Truijers, M., Tutein Nolthenius, R.P., van der Vliet, J.A., Vos, C.G., Vos, G.A., Voute, M.T., de Vries, A.C., de Vries, M., van de Water, W., Welten, G.M., Wouda, R., Yazar, O., Yeung, K.K.

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Considerations for radiotherapy in Bloom Syndrome: A case series by Schoenaker, M.H.D., Takada, S., van Deuren, M., Dommering, C.J., Henriët, S.S.V., Pico, I., Vogel, W.V., Weemaes, C.M.R., Willemsen, M.A.A.P., van der Burg, M., Kaanders, J.H.A.M.

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Failure to Rescue – a Closer Look at Mortality Rates Has No Added Value for Hospital Comparisons but Is Useful for Team Quality Assessment in Abdominal Aortic Aneurysm Surgery in T... by Vahl, Anco, van Zwet, Erik W., Tollenaar, Robertus A.E.M., Akkersdijk, G.P., Akkersdijk, W.L., Arts, C.H., Avontuur, J.A., Baal, J.G., Bakker, O.J., Balm, R., Barendregt, W.B., Bender, M.H., van den Berg, M., Beuk, R.J., Bleker, R.J., Bosma, J., Brinckman, M.J., van den Broek, T.H., Brom, H.L., Brummel, P., van Brussel, J.P., den Butter, G., Cancrinus, E., Castenmiller, P.H., Coveliers, H.M., Dawson, I., Dolmans, D.E., van Eijck, G.J., Elshof, J.W., de Fijter, W.M., Fritschy, W.M., Geelkerken, R.H., Govaert, B., de Groot, H.G., Hajer, G.F., Hazenberg, C.E., Helleman, J.N., Hendriks, J.M., Heyligers, J.M., den Hoed, P.T., Hoencamp, R., Hollander, E.J., Huisman, L.C., Jansbeken, J.R., Jiang, H.H., de Jong, S.C., Keller, B.P., Khodadade Jahrome, A., Koedam, N.A., Kolkert, J.L., Koning, G.G., Krasznai, A.G., van der Laan, M.J., van Laanen, J.H., Lawson, J.A., Legemate, D.A., Lind, R.C., Loos, M.J., Mahmoud, D.E., Metz, R., de Mol van Otterloo, J.C., Montauban van Swijndregt, Y.C., Morak, M.J., Nederhoed, J.H., de Nie, A.J., Poyck, P.P., Prent, A., ten Raa, S., Reichart, M., Saleem, B.R., van ’t Sant, H.P., Schepers, A., Schol, F.P., Schreinemacher, M.H., Smeets, H.J., de Smet, A.A., Sondakh, A.O., Stigter, D.A., Stigter, H., The, R.M., van Tongeren, R.B., Tordoir, J.H., Tournoij, E., Tutein Nolthenius, R.P., Veger, H.T., Visser, M.J., Vlijmen-van Keulen, C.J., Voesten, H.G., Vos, A.W., Vos, G.A., Vriens, P.W., de Vries, J.P., van Walraven, L.A., Welten, R.J., Wille, J., Willigendael, E.M., Witte, M.E., Wittens, C.H., Wolf-de Jonge, I.C., Yazar, O.

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The Dutch Audit of Carotid Interventions: Transparency in Quality of Carotid Endarterectomy in Symptomatic Patients in the Netherlands by Karthaus, Eleonora G., Vahl, Anco, Hamming, Jaap F., Akkersdijk, G.P., Akkersdijk, W.L., Arts, C.H., Avontuur, J.A., Baal, J.G., Bakker, O.J., Balm, R., Barendregt, W.B., Bender, M.H., van den Berg, M., Bosma, J., Brinckman, M.J., van den Broek, T.H., Brummel, P., van Brussel, J.P., den Butter, G., Cancrinus, E., Castenmiller, P.H., Coveliers, H.M., Dawson, I., Dolmans, D.E., van Eijck, G.J., Elshof, J.W., de Fijter, W.M., Fritschy, W.M., Geelkerken, R.H., Govaert, B., de Groot, H.G., Hajer, G.F., Hazenberg, C.E., Helleman, J.N., Hendriks, J.M., Heyligers, J.M., den Hoed, P.T., Hoencamp, R., Hollander, E.J., Huisman, L.C., Jansbeken, J.R., Jiang, H.H., de Jong, S.C., Keller, B.P., Khodadade Jahrome, A., Koedam, N.A., Kolkert, J.L., Koning, G.G., Krasznai, A.G., van der Laan, M.J., van Laanen, J.H., Lawson, J.A., Legemate, D.A., Lind, R.C., Loos, M.J., Mahmoud, D.E., Metz, R., de Mol van Otterloo, J.C., Montauban van Swijndregt, Y.C., Morak, M.J., Nederhoed, J.H., Poyck, P.P., Prent, A., ten Raa, S., Reichart, M., Saleem, B.R., van 't Sant, H.P., Schepers, A., Schol, F.P., Schreinemacher, M.H., de Smet, A.A., Sondakh, A.O., Stigter, D.A., Stigter, H., The, R.M., van Tongeren, R.B., Tordoir, J.H., Tournoij, E., Tutein Nolthenius, R.P., Veger, H.T., Visser, M.J., Vlijmen - van Keulen, C.J., Voesten, H.G., Vos, A.W., Vos, G.A., Vriens, P.W., de Vries, J.P., van Walraven, L.A., Welten, R.J., Wille, J., Willigendael, E.M., Witte, M.E., Wittens, C.H., Wolf-de Jonge, I.C., Yazar, O., de Borst, Gert J., Elsman, Bernard H.P., Elshof, Jan-Willem, Hamming, Jaap F., Vahl, Anco

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PO-105 Quantification of citrullinated histones in human blood samples: challenges and development of a nucleosome-based assay to quantify H3Cit-DNA in human plasma by Thålin, A., Aguilera, K., Hall, N.W., Marunde, M.R., Burg, J.M., Rosell, A., Daleskog, M., Hisada, Y., Meiners, M.J., Sun, Z.W., Whelihan, M.F., Cheek, M.A., Howard, S.A., Saxena-Beem, S., Noubouossie, D.F., Key, N.S., Sheikh, S.Z., Keogh, M.C., Cowles, M.W., Lundström, S., Mackman, N., Wallén, H., Johnstone, A.L.

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IgM Augments Complement Bactericidal Activity with Serum from a Patient with a Novel CD79a Mutation by Langereis, Jeroen D., Henriet, Stefanie S, Kuipers, Saskia, Weemaes, Corry M.R., van der Burg, Mirjam, de Jonge, Marien I., van der Flier, Michiel

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Short chain fatty acids stimulate Angiopoietin-like 4 synthesis in human colon adenocarcinoma cells by activating PPARy by Alex, S, Lange, K, Amolo, T, Grinstead, J.S, Haakonsson, A.K, Szalowska, E, Koppen, A, Mudde, C.M, Haenen, D, Al-Lahham, S, Roelofsen, H, Houtman, R, Burg, B., van der, Mandrup, S, Bonvin, A.M.J.J, Kalkhoven, E, Muller, M.R, Hooiveld, G.J.E.J, Kersten, A.H

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