ATP5PO levels regulate enteric nervous system development in zebrafish, linking Hirschsprung disease to Down Syndrome

by Kuil, L.E., Chauhan, R.K., de Graaf, B.M., Cheng, W.W., Kakiailatu, N.J.M., Lasabuda, R., Verhaeghe, C., Windster, J.D., Schriemer, D., Azmani, Z., Brooks, A.S., Edie, S., Reeves, R.H., Eggen, B.J.L., Shepherd, I.T., Burns, A.J., Hofstra, R.M.W., Melotte, V., Brosens, E., Alves, M.M.
Published in Biochimica et biophysica acta. Molecular basis of disease

Nimbus: a design-driven analyses suite for amplicon-based NGS data

by Brouwer, R W W, van den Hout, M C G N, Kockx, C E M, Brosens, E, Eussen, B, de Klein, A, Sleutels, F, van IJcken, W F J
Published in Bioinformatics

VACTERL Association Etiology: The Impact of de novo and Rare Copy Number Variations

by Brosens, E., Eussen, H., van Bever, Y., van der Helm, R.M., Ijsselstijn, H., Zaveri, H.P., Wijnen, R., Scott, D.A., Tibboel, D., de Klein, A.
Published in Molecular syndromology

Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax

by Versées, W., Decanniere, K., Pellé, R., Depoorter, J., Brosens, E., Parkin, D.W., Steyaert, J.
Published in Journal of molecular biology

Recommendations for whole genome sequencing in diagnostics for rare diseases

by Souche, Erika, Beltran, Sergi, Brosens, Erwin, Belmont, John W, Fossum, Magdalena, Riess, Olaf, Gilissen, Christian, Ardeshirdavani, Amin, Houge, Gunnar, van Gijn, Marielle, Clayton-Smith, Jill, Synofzik, Matthis, de Leeuw, Nicole, Deans, Zandra C, Dincer, Yasemin, Eck, Sebastian H, van der Crabben, Saskia, Balasubramanian, Meena, Graessner, Holm, Sturm, Marc, Firth, Helen, Ferlini, Alessandra, Nabbout, Rima, De Baere, Elfride, Liehr, Thomas, Macek, Milan, Matthijs, Gert, Scheffer, Hans, Bauer, Peter, Yntema, Helger G, Weiss, Marjan M
Published in European journal of human genetics : EJHG

The Conserved Active Site Proline Determines the Reducing Power of Staphylococcus aureus Thioredoxin

by Roos, Goedele, Garcia-Pino, Abel, Van belle, Karolien, Brosens, Elke, Wahni, Khadija, Vandenbussche, Guy, Wyns, Lode, Loris, Remy, Messens, Joris
Published in Journal of molecular biology

DOZ047.32: Infantile hypertrophic pyloric stenosis in patients with esophageal atresia: proposal for a causative seesaw model

by Ten Kate, C A, Brouwer, R W W, van Bever, Y, Martens, V K, Brands, T, van Beelen, N W G, Brooks, A S, Huigh, D, Eussen, H, van IJcken, W F J, IJsselstijn, H, Tibboel, D, Wijnen, R M H, de Klein, A, Hofstra, R M W, Brosens, E
Published in Diseases of the esophagus

Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax11Edited by R. Huber

by Versées, W., Decanniere, K., Pellé, R., Depoorter, J., Brosens, E., Parkin, D.W., Steyaert, J.
Published in Journal of molecular biology

First genome-wide association study of esophageal atresia identifies three genetic risk loci at CTNNA3, FOXF1/FOXC2/FOXL1, and HNF1B

by Gehlen, Jan, Giel, Ann-Sophie, Köllges, Ricarda, Haas, Stephan L., Zhang, Rong, Trcka, Jiri, Sungur, Ayse Ö., Renziehausen, Florian, Bornholdt, Dorothea, Jung, Daphne, Hoyer, Paul D., Nordenskjöld, Agneta, Tibboel, Dick, Vlot, John, Spaander, Manon C.W., Smigiel, Robert, Patkowski, Dariusz, Roeleveld, Nel, van Rooij, Iris ALM, de Blaauw, Ivo, Hölscher, Alice, Pauly, Marcus, Leutner, Andreas, Fuchs, Joerg, Niethammer, Joel, Melissari, Maria-Theodora, Jenetzky, Ekkehart, Zwink, Nadine, Thiele, Holger, Hilger, Alina Christine, Hess, Timo, Trautmann, Jessica, Marks, Matthias, Baumgarten, Martin, Bläss, Gaby, Landén, Mikael, Fundin, Bengt, Bulik, Cynthia M., Pennimpede, Tracie, Ludwig, Michael, Ludwig, Kerstin U., Mangold, Elisabeth, Heilmann-Heimbach, Stefanie, Moebus, Susanne, Herrmann, Bernhard G., Alsabeah, Kristina, Burgos, Carmen M., Lilja, Helene E., Azodi, Sahar, Stenström, Pernilla, Arnbjörnsson, Einar, Frybova, Barbora, Lebensztejn, Dariusz M., Debek, Wojciech, Kolodziejczyk, Elwira, Kozera, Katarzyna, Kierkus, Jaroslaw, Kaliciński, Piotr, Stefanowicz, Marek, Socha-Banasiak, Anna, Kolejwa, Michal, Piaseczna-Piotrowska, Anna, Czkwianianc, Elzbieta, Nöthen, Markus M., Grote, Phillip, Rygl, Michal, Reinshagen, Konrad, Spychalski, Nicole, Ludwikowski, Barbara, Hubertus, Jochen, Heydweiller, Andreas, Ure, Benno, Muensterer, Oliver J., Aubert, Ophelia, Gosemann, Jan-Hendrik, Lacher, Martin, Degenhardt, Petra, Boemers, Thomas M., Mokrowiecka, Anna, Małecka-Panas, Ewa, Wöhr, Markus, Knapp, Michael, Seitz, Guido, de Klein, Annelies, Oracz, Grzegorz, Brosens, Erwin, Reutter, Heiko, Schumacher, Johannes
Published in HGG advances

Small noncoding differentially methylated copy-number variants, including IncRNA genes, cause a lethal lung developmental disorder

by Szafranski, P, Dharmadhikari, A V, Brosens, E, Gurha, P, Kolodziejska, KE, Zhishuo, O, Dittwald, P, Majewski, T, Mohan, K N, Chen, B, Person, R E, Tibboel, D, de Klein, A, Stankiewicz, P
Published in Genome research

All Intermediates of the Arsenate Reductase Mechanism, Including an Intramolecular Dynamic Disulfide Cascade

by Messens, Joris, Martins, José C., Van Belle, Karolien, Brosens, Elke, Desmyter, Aline, De Gieter, Marjan, Wieruszeski, Jean-Michel, Willem, Rudolph, Wyns, Lode, Zegers, Ingrid
Published in Proceedings of the National Academy of Sciences - PNAS

Kinetics and active site dynamics of Staphylococcus aureus arsenate reductase

by Messens, Joris, Martins, José C, Brosens, Elke, Van Belle, Karolien, Jacobs, Doris M, Willem, Rudolph, Wyns, Lode
Published in Journal of biological inorganic chemistry

Solving the phase problem for carbohydrate-binding proteins using selenium derivatives of their ligands: a case study involving the bacterial F17-G adhesin

by Buts, Lieven, Loris, Remy, De Genst, Erwin, Oscarson, Stefan, Lahmann, Martina, Messens, Joris, Brosens, Elke, Wyns, Lode, De Greve, Henri, Bouckaert, Julie
Published in Acta crystallographica. Section D, Biological crystallography.

Purification of an oxidation-sensitive enzyme, pI258 arsenate reductase from Staphylococcus aureus

by Messens, Joris, Martins, José C., Zegers, Ingrid, Van Belle, Karolien, Brosens, Elke, Wyns, Lode
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development of a downstream process for the isolation of Staphylococcus aureus arsenate reductase overproduced in Escherichia coli

by Messens, Joris, Hayburn, Gaynor, Brosens, Elke, Laus, Georges, Wyns, Lode
Published in Journal of chromatography. B, Biomedical sciences and applications

1H, 13C and 15N backbone resonance assignment of the arsenate reductase from Staphylococcus aureus in its reduced state

by Jacobs, D M, Messens, J, Wechselberger, R W, Brosens, E, Willem, R, Wyns, L, Martin, J C
Published in Journal of biomolecular NMR

The impact of uterine immaturity on obstetrical syndromes during adolescence

by Brosens, Ivo, MD, PhD, Muter, Joanne, PhD, Gargett, Caroline, PhD, Puttemans, Patrick, MD, Benagiano, Giuseppe, MD, PhD, Brosens, Jan J., MD, PhD
Published in American journal of obstetrics and gynecology

Pancreatic cancer organoids recapitulate disease and allow personalized drug screening

by Driehuis, Else, van Hoeck, Arne, Moore, Kat, Kolders, Sigrid, Francies, Hayley E., Gulersonmez, M. Can, Stigter, Edwin C. A., Burgering, Boudewijn, Geurts, Veerle, Gracanin, Ana, Bounova, Gergana, Morsink, Folkert H., Vries, Robert, Boj, Sylvia, van Es, Johan, Offerhaus, G. Johan A., Kranenburg, Onno, Garnett, Mathew J., Wessels, Lodewyk, Cuppen, Edwin, Brosens, Lodewijk A. A., Clevers, Hans
Published in Proceedings of the National Academy of Sciences - PNAS

Risk of colorectal cancer in juvenile polyposis

by Brosens, Lodewijk A A, van Hattem, Arnout, Hylind, Linda M, Iacobuzio-Donahue, Christine, Romans, Katharine E, Axilbund, Jennifer, Cruz-Correa, Marcia, Tersmette, Anne C, Offerhaus, G Johan A, Giardiello, Francis M
Published in Gut

The perinatal origins of major reproductive disorders in the adolescent: Research avenues

by Brosens, I, Ćurčić, A, Vejnović, T, Gargett, C.E, Brosens, J.J, Benagiano, G
Published in Placenta (Eastbourne)