Akkermansia muciniphila phospholipid induces homeostatic immune responses

by Bae, Munhyung, Cassilly, Chelsi D., Liu, Xiaoxi, Park, Sung-Moo, Tusi, Betsabeh Khoramian, Chen, Xiangjun, Kwon, Jaeyoung, Filipčík, Pavel, Bolze, Andrew S., Liu, Zehua, Vlamakis, Hera, Graham, Daniel B., Buhrlage, Sara J., Xavier, Ramnik J., Clardy, Jon
Published in Nature (London)

Collinsella aerofaciens Produces a pH-Responsive Lipid Immunogen

by Kwon, Jaeyoung, Bae, Munhyung, Szamosvári, Dávid, Cassilly, Chelsi D., Bolze, Andrew S., Jackson, David R., Xavier, Ramnik J., Clardy, Jon
Published in Journal of the American Chemical Society

A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection

by Casanova, Jean-Laurent, Su, Helen C., Abel, Laurent, Aiuti, Alessandro, Almuhsen, Saleh, Arias, Andres Augusto, Bastard, Paul, Biggs, Catherine, Bogunovic, Dusan, Boisson, Bertrand, Boisson-Dupuis, Stephanie, Bolze, Alexandre, Bondarenko, Anastasia, Bousfiha, Aziz, Brodin, Petter, Bustamante, Jacinta, Butte, Manish, Casari, Giorgio, Ciancanelli, Michael, Cobat, Aurelie, Condino-Neto, Antonio, Cooper, Megan, Dalgard, Clifton, Espinosa, Sara, Feldman, Hagit, Fellay, Jacques, Franco, Jose Luis, Hagin, David, Itan, Yuval, Jouanguy, Emmanuelle, Lucas, Carrie, Mansouri, Davood, Meyts, Isabelle, Milner, Joshua, Mogensen, Trine, Morio, Tomohiro, Ng, Lisa, Notarangelo, Luigi D., Okada, Satoshi, Ozcelik, Tayfun, Soler Palacín, Pere, Planas, Anna, Prando, Carolina, Puel, Anne, Pujol, Aurora, Redin, Claire, Renia, Laurent, Rodriguez Gallego, Jose Carlos, Quintana-Murci, Lluis, Sancho-Shimizu, Vanessa, Sankaran, Vijay, Seppänen, Mikko R.J., Shahrooei, Mohammad, Snow, Andrew, Spaan, András, Tangye, Stuart, Tur, Jordi Perez, Turvey, Stuart, Vinh, Donald C., von Bernuth, Horst, Wang, Xiaochuan, Zawadzki, Pawel, Zhang, Qian, Zhang, Shenying
Published in Cell

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

by Bastard, Paul, Rosen, Lindsey B, Zhang, Qian, Michailidis, Eleftherios, Hoffmann, Hans-Heinrich, Zhang, Yu, Dorgham, Karim, Philippot, Quentin, Rosain, Jérémie, Béziat, Vivien, Manry, Jérémy, Shaw, Elana, Haljasmägi, Liis, Peterson, Pärt, Lorenzo, Lazaro, Bizien, Lucy, Trouillet-Assant, Sophie, Dobbs, Kerry, de Jesus, Adriana Almeida, Belot, Alexandre, Kallaste, Anne, Catherinot, Emilie, Tandjaoui-Lambiotte, Yacine, Le Pen, Jeremie, Kerner, Gaspard, Bigio, Benedetta, Seeleuthner, Yoann, Yang, Rui, Bolze, Alexandre, Spaan, András N, Delmonte, Ottavia M, Abers, Michael S, Aiuti, Alessandro, Casari, Giorgio, Lampasona, Vito, Piemonti, Lorenzo, Ciceri, Fabio, Bilguvar, Kaya, Lifton, Richard P, Vasse, Marc, Smadja, David M, Migaud, Mélanie, Hadjadj, Jérome, Terrier, Benjamin, Duffy, Darragh, Quintana-Murci, Lluis, van de Beek, Diederik, Roussel, Lucie, Vinh, Donald C, Tangye, Stuart G, Haerynck, Filomeen, Dalmau, David, Martinez-Picado, Javier, Brodin, Petter, Nussenzweig, Michel C, Boisson-Dupuis, Stéphanie, Rodríguez-Gallego, Carlos, Vogt, Guillaume, Mogensen, Trine H, Oler, Andrew J, Gu, Jingwen, Burbelo, Peter D, Cohen, Jeffrey I, Biondi, Andrea, Bettini, Laura Rachele, D'Angio, Mariella, Bonfanti, Paolo, Rossignol, Patrick, Mayaux, Julien, Rieux-Laucat, Frédéric, Husebye, Eystein S, Fusco, Francesca, Ursini, Matilde Valeria, Imberti, Luisa, Sottini, Alessandra, Paghera, Simone, Quiros-Roldan, Eugenia, Rossi, Camillo, Castagnoli, Riccardo, Montagna, Daniela, Licari, Amelia, Marseglia, Gian Luigi, Duval, Xavier, Ghosn, Jade, Tsang, John S, Goldbach-Mansky, Raphaela, Kisand, Kai, Lionakis, Michail S, Puel, Anne, Zhang, Shen-Ying, Holland, Steven M, Gorochov, Guy, Jouanguy, Emmanuelle, Rice, Charles M, Cobat, Aurélie, Notarangelo, Luigi D, Abel, Laurent, Su, Helen C, Casanova, Jean-Laurent
Published in Science

Ribosomal Protein SA Haploinsufficiency in Humans with Isolated Congenital Asplenia

by Bolze, Alexandre, Mahlaoui, Nizar, Byun, Minji, Turner, Bridget, Trede, Nikolaus, Ellis, Steven R., Abhyankar, Avinash, Itan, Yuval, Patin, Etienne, Brebner, Samuel, Sackstein, Paul, Puel, Anne, Picard, Capucine, Abel, Laurent, Quintana-Murci, Lluis, Faust, Saul N., Williams, Anthony P., Baretto, Richard, Duddridge, Michael, Kini, Usha, Pollard, Andrew J., Gaud, Catherine, Frange, Pierre, Orbach, Daniel, Emile, Jean-Francois, Stephan, Jean-Louis, Sorensen, Ricardo, Plebani, Alessandro, Hammarstrom, Lennart, Conley, Mary Ellen, Selleri, Licia, Casanova, Jean-Laurent
Published in Science (American Association for the Advancement of Science)

Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia

by Zhang, Qian, Matuozzo, Daniela, Le Pen, Jérémie, Lee, Danyel, Moens, Leen, Asano, Takaki, Bohlen, Jonathan, Liu, Zhiyong, Moncada-Velez, Marcela, Kendir-Demirkol, Yasemin, Jing, Huie, Bizien, Lucy, Marchal, Astrid, Abolhassani, Hassan, Delafontaine, Selket, Bucciol, Giorgia, Bayhan, Gulsum Ical, Keles, Sevgi, Kiykim, Ayca, Hancerli, Selda, Haerynck, Filomeen, Florkin, Benoit, Hatipoglu, Nevin, Ozcelik, Tayfun, Morelle, Guillaume, Zatz, Mayana, Ng, Lisa F P, Lye, David Chien, Young, Barnaby Edward, Leo, Yee-Sin, Dalgard, Clifton L, Lifton, Richard P, Renia, Laurent, Meyts, Isabelle, Jouanguy, Emmanuelle, Hammarström, Lennart, Pan-Hammarström, Qiang, Boisson, Bertrand, Bastard, Paul, Su, Helen C, Boisson-Dupuis, Stéphanie, Abel, Laurent, Rice, Charles M, Zhang, Shen-Ying, Cobat, Aurélie, Casanova, Jean-Laurent
Published in The Journal of experimental medicine

SARS-CoV-2 variant Delta rapidly displaced variant Alpha in the United States and led to higher viral loads

by Bolze, Alexandre, Luo, Shishi, White, Simon, Cirulli, Elizabeth T., Wyman, Dana, Dei Rossi, Andrew, Machado, Henrique, Cassens, Tyler, Jacobs, Sharoni, Schiabor Barrett, Kelly M., Tanudjaja, Francisco, Tsan, Kevin, Nguyen, Jason, Ramirez, Jimmy M., Sandoval, Efren, Wang, Xueqing, Wong, David, Becker, David, Laurent, Marc, Lu, James T., Isaksson, Magnus, Washington, Nicole L., Lee, William
Published in Cell reports. Medicine

Redox Behavior of Cyclo[6]pyrrole in the Formation of a Uranyl Complex

by Melfi, Patricia J, Kim, Sung Kuk, Lee, Jeong Tae, Bolze, Frédéric, Seidel, Daniel, Lynch, Vincent M, Veauthier, Jacqueline M, Gaunt, Andrew J, Neu, Mary P, Ou, Zhongping, Kadish, Karl M, Fukuzumi, Shunichi, Ohkubo, Kei, Sessler, Jonathan L
Published in Inorganic chemistry

Autoantibodies against type I IFNs in patients with critical influenza pneumonia

by Zhang, Qian, Pizzorno, Andrés, Miorin, Lisa, Bastard, Paul, Gervais, Adrian, Le Voyer, Tom, Bizien, Lucy, Manry, Jeremy, Rosain, Jérémie, Philippot, Quentin, Goavec, Kelian, Padey, Blandine, Cupic, Anastasija, Laurent, Emilie, Saker, Kahina, Vanker, Martti, Särekannu, Karita, García-Salum, Tamara, Ferres, Marcela, Le Corre, Nicole, Sánchez-Céspedes, Javier, Balsera-Manzanero, María, Carratala, Jordi, Retamar-Gentil, Pilar, Abelenda-Alonso, Gabriela, Valiente, Adoración, Tiberghien, Pierre, Zins, Marie, Debette, Stéphanie, Meyts, Isabelle, Haerynck, Filomeen, Castagnoli, Riccardo, Notarangelo, Luigi D, Gonzalez-Granado, Luis I, Dominguez-Pinilla, Nerea, Andreakos, Evangelos, Triantafyllia, Vasiliki, Rodríguez-Gallego, Carlos, Solé-Violán, Jordi, Ruiz-Hernandez, José Juan, Rodríguez de Castro, Felipe, Ferreres, José, Briones, Marisa, Wauters, Joost, Vanderbeke, Lore, Feys, Simon, Kuo, Chen-Yen, Lei, Wei-Te, Ku, Cheng-Lung, Tal, Galit, Etzioni, Amos, Hanna, Suhair, Fournet, Thomas, Casalegno, Jean-Sebastien, Queromes, Gregory, Argaud, Laurent, Javouhey, Etienne, Rosa-Calatrava, Manuel, Cordero, Elisa, Aydillo, Teresa, Medina, Rafael A, Kisand, Kai, Puel, Anne, Jouanguy, Emmanuelle, Abel, Laurent, Cobat, Aurélie, Trouillet-Assant, Sophie, García-Sastre, Adolfo, Casanova, Jean-Laurent
Published in The Journal of experimental medicine

Respiratory viral infections in otherwise healthy humans with inherited IRF7 deficiency

by Campbell, Tessa Mollie, Liu, Zhiyong, Zhang, Qian, Moncada-Velez, Marcela, Covill, Laura E, Zhang, Peng, Alavi Darazam, Ilad, Bastard, Paul, Bizien, Lucy, Bucciol, Giorgia, Lind Enoksson, Sara, Jouanguy, Emmanuelle, Karabela, Şemsi Nur, Khan, Taushif, Kendir-Demirkol, Yasemin, Arias, Andres Augusto, Mansouri, Davood, Marits, Per, Marr, Nico, Migeotte, Isabelle, Moens, Leen, Ozcelik, Tayfun, Pellier, Isabelle, Sendel, Anton, Şenoğlu, Sevtap, Shahrooei, Mohammad, Smith, C I Edvard, Vandernoot, Isabelle, Willekens, Karen, Kart Yaşar, Kadriye, Bergman, Peter, Abel, Laurent, Cobat, Aurélie, Casanova, Jean-Laurent, Meyts, Isabelle, Bryceson, Yenan T
Published in The Journal of experimental medicine

Whole-Exome-Sequencing-Based Discovery of Human FADD Deficiency

by Bolze, Alexandre, Byun, Minji, McDonald, David, Morgan, Neil V., Abhyankar, Avinash, Premkumar, Lakshmanane, Puel, Anne, Bacon, Chris M., Rieux-Laucat, Frédéric, Pang, Ki, Britland, Alison, Abel, Laurent, Cant, Andrew, Maher, Eamonn R., Riedl, Stefan J., Hambleton, Sophie, Casanova, Jean-Laurent
Published in American journal of human genetics

Incomplete penetrance for isolated congenital asplenia in humans with mutations in translated and untranslated RPSA exons

by Bolze, Alexandre, Boisson, Bertrand, Bosch, Barbara, Antipenko, Alexander, Bouaziz, Matthieu, Sackstein, Paul, Chaker-Margot, Malik, Barlogis, Vincent, Briggs, Tracy, Colino, Elena, Elmore, Aurora C., Fischer, Alain, Genel, Ferah, Hewlett, Angela, Jedidi, Maher, Kelecic, Jadranka, Krüger, Renate, Ku, Cheng-Lung, Kumararatne, Dinakantha, Lefevre-Utile, Alain, Loughlin, Sam, Mahlaoui, Nizar, Markus, Susanne, Garcia, Juan-Miguel, Nizon, Mathilde, Oleastro, Matias, Pac, Malgorzata, Picard, Capucine, Pollard, Andrew J., Rodriguez-Gallego, Carlos, Thomas, Caroline, Von Bernuth, Horst, Worth, Austen, Meyts, Isabelle, Risolino, Maurizio, Selleri, Licia, Puel, Anne, Klinge, Sebastian, Abel, Laurent, Casanova, Jean-Laurent
Published in Proceedings of the National Academy of Sciences - PNAS

Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia

by García-García, Ana, Pérez de Diego, Rebeca, Flores, Carlos, Rinchai, Darawan, Solé-Violán, Jordi, Deyà-Martínez, Àngela, García-Solis, Blanca, Lorenzo-Salazar, José M, Hernández-Brito, Elisa, Lanz, Anna-Lisa, Moens, Leen, Bucciol, Giorgia, Almuqamam, Mohamed, Domachowske, Joseph B, Colino, Elena, Santos-Perez, Juan Luis, Marco, Francisco M, Pignata, Claudio, Bousfiha, Aziz, Turvey, Stuart E, Bauer, Stefanie, Haerynck, Filomeen, Ocejo-Vinyals, Javier Gonzalo, Lendinez, Francisco, Prader, Seraina, Naumann-Bartsch, Nora, Pachlopnik Schmid, Jana, Biggs, Catherine M, Hildebrand, Kyla, Dreesman, Alexandra, Cárdenes, Miguel Ángel, Ailal, Fatima, Benhsaien, Ibtihal, Giardino, Giuliana, Molina-Fuentes, Agueda, Fortuny, Claudia, Madhavarapu, Swetha, Conway, Daniel H, Prando, Carolina, Schidlowski, Laire, Martínez de Saavedra Álvarez, María Teresa, Alfaro, Rafael, Rodríguez de Castro, Felipe, Meyts, Isabelle, Hauck, Fabian, Puel, Anne, Bastard, Paul, Boisson, Bertrand, Jouanguy, Emmanuelle, Abel, Laurent, Cobat, Aurélie, Zhang, Qian, Casanova, Jean-Laurent, Alsina, Laia, Rodríguez-Gallego, Carlos
Published in The Journal of experimental medicine

A Call to Action for Intermediate and Secondary School Lifestyle Medicine Education: Instating Healthy Teen Behaviors

by Tollefson, Michelle, Kees, Alexandra, Bolze, Andrew, Wolferz, Richard, Plaven, Brittany, Frates, Elizabeth Pegg
Published in American journal of lifestyle medicine

Students Teaching Students: Bringing Lifestyle Medicine Education to Middle and High Schools Through Student-Led Community Outreach Programs

by Wolferz, Richard, Arjani, Simran, Bolze, Andrew, Frates, Elizabeth Pegg
Published in American journal of lifestyle medicine

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

by Bastard, Paul, Rosen, Lindsey B., Zhang, Qian, Michailidis, Eleftherios, Hoffmann, Hans-Heinrich, Zhang, Yu, Dorgham, Karim, Philippot, Quentin, Rosain, Jérémie, Béziat, Vivien, Manry, Jérémy, Shaw, Elana, Haljasmägi, Liis, Peterson, Pärt, Lorenzo, Lazaro, Bizien, Lucy, Trouillet-Assant, Sophie, Dobbs, Kerry, de Jesus, Adriana Almeida, Belot, Alexandre, Kallaste, Anne, Catherinot, Emilie, Tandjaoui-Lambiotte, Yacine, Le Pen, Jeremie, Kerner, Gaspard, Bigio, Benedetta, Seeleuthner, Yoann, Yang, Rui, Bolze, Alexandre, Spaan, András N., Delmonte, Ottavia M., Abers, Michael S., Aiuti, Alessandro, Casari, Giorgio, Lampasona, Vito, Piemonti, Lorenzo, Ciceri, Fabio, Bilguvar, Kaya, Lifton, Richard P., Vasse, Marc, Smadja, David, Migaud, Mélanie, Hadjadj, Jérome, Terrier, Benjamin, Duffy, Darragh, Quintana-Murci, Lluis, van de Beek, Diederik, Roussel, Lucie, Vinh, Donald C., Tangye, Stuart G., Haerynck, Filomeen, Dalmau, David, Martinez-Picado, Javier, Brodin, Petter, Nussenzweig, Michel C., Boisson-Dupuis, Stéphanie, Rodríguez-Gallego, Carlos, Vogt, Guillaume, Mogensen, Trine H., Oler, Andrew J., Gu, Jingwen, Burbelo, Peter D., Cohen, Jeffrey, Biondi, Andrea, Bettini, Laura Rachele, d'Angio, Mariella, Bonfanti, Paolo, Rossignol, Patrick, Mayaux, Julien, Rieux-Laucat, Frédéric, Husebye, Eystein S., Fusco, Francesca, Ursini, Matilde Valeria, Imberti, Luisa, Sottini, Alessandra, Paghera, Simone, Quiros-Roldan, Eugenia, Rossi, Camillo, Castagnoli, Riccardo, Montagna, Daniela, Licari, Amelia, Marseglia, Gian Luigi, Duval, Xavier, Ghosn, Jade, Tsang, John S., Goldbach-Mansky, Raphaela, Kisand, Kai, Lionakis, Michail S., Puel, Anne, Zhang, Shen-Ying, Holland, Steven M., Gorochov, Guy, Jouanguy, Emmanuelle, Rice, Charles M., Cobat, Aurélie, Notarangelo, Luigi D., Abel, Laurent, Richard, Jean-Christophe, Su, Helen, Casanova, Jean-Laurent
Published in Science (American Association for the Advancement of Science)

Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection

by Marchal, Astrid, Cirulli, Elizabeth T, Neveux, Iva, Bellos, Evangelos, Thwaites, Ryan S, Schiabor Barrett, Kelly M, Zhang, Yu, Nemes-Bokun, Ivana, Kalinova, Mariya, Catchpole, Andrew, Tangye, Stuart G, Spaan, András N, Lack, Justin B, Ghosn, Jade, Burdet, Charles, Gorochov, Guy, Tubach, Florence, Hausfater, Pierre, Dalgard, Clifton L, Zhang, Shen-Ying, Zhang, Qian, Chiu, Christopher, Fellay, Jacques, Grzymski, Joseph J, Sancho-Shimizu, Vanessa, Abel, Laurent, Casanova, Jean-Laurent, Cobat, Aurélie, Bolze, Alexandre
Published in HGG advances