Spatiotemporal Coupling of the Hepatitis C Virus Replication Cycle by Creating a Lipid Droplet- Proximal Membranous Replication Compartment

by Lee, Ji-Young, Cortese, Mirko, Haselmann, Uta, Tabata, Keisuke, Romero-Brey, Inés, Funaya, Charlotta, Schieber, Nicole L., Qiang, Yu, Bartenschlager, Marie, Kallis, Stephanie, Ritter, Christian, Rohr, Karl, Schwab, Yannick, Ruggieri, Alessia, Bartenschlager, Ralf
Published in Cell reports (Cambridge)

Ultrastructural Characterization of Zika Virus Replication Factories

by Cortese, Mirko, Goellner, Sarah, Acosta, Eliana Gisela, Neufeldt, Christopher John, Oleksiuk, Olga, Lampe, Marko, Haselmann, Uta, Funaya, Charlotta, Schieber, Nicole, Ronchi, Paolo, Schorb, Martin, Pruunsild, Priit, Schwab, Yannick, Chatel-Chaix, Laurent, Ruggieri, Alessia, Bartenschlager, Ralf
Published in Cell reports (Cambridge)

Neutralizing antibody response against the B.1.617.2 (delta) and the B.1.1.529 (omicron) variants after a third mRNA SARS‐CoV‐2 vaccine dose in kidney transplant recipients

by Benning, Louise, Morath, Christian, Bartenschlager, Marie, Kim, Heeyoung, Reineke, Marvin, Beimler, Jörg, Buylaert, Mirabel, Nusshag, Christian, Kälble, Florian, Reichel, Paula, Töllner, Maximilian, Schaier, Matthias, Klein, Katrin, Benes, Vladimir, Rausch, Tobias, Rieger, Susanne, Stich, Maximilian, Tönshoff, Burkhard, Weidner, Niklas, Schnitzler, Paul, Zeier, Martin, Süsal, Caner, Hien Tran, Thuong, Bartenschlager, Ralf, Speer, Claudius
Published in American journal of transplantation

Global analysis of protein-RNA interactions in SARS-CoV-2-infected cells reveals key regulators of infection

by Kamel, Wael, Noerenberg, Marko, Cerikan, Berati, Chen, Honglin, Järvelin, Aino I., Kammoun, Mohamed, Lee, Jeffrey Y., Shuai, Ni, Garcia-Moreno, Manuel, Andrejeva, Anna, Deery, Michael J., Johnson, Natasha, Neufeldt, Christopher J., Cortese, Mirko, Knight, Michael L., Lilley, Kathryn S., Martinez, Javier, Davis, Ilan, Bartenschlager, Ralf, Mohammed, Shabaz, Castello, Alfredo
Published in Molecular cell

Three-dimensional architecture and biogenesis of membrane structures associated with hepatitis C virus replication

by Romero-Brey, Inés, Merz, Andreas, Chiramel, Abhilash, Lee, Ji-Young, Chlanda, Petr, Haselman, Uta, Santarella-Mellwig, Rachel, Habermann, Anja, Hoppe, Simone, Kallis, Stephanie, Walther, Paul, Antony, Claude, Krijnse-Locker, Jacomine, Bartenschlager, Ralf
Published in PLoS pathogens

Deciphering the Origin and Evolution of Hepatitis B Viruses by Means of a Family of Non-enveloped Fish Viruses

by Lauber, Chris, Seitz, Stefan, Mattei, Simone, Suh, Alexander, Beck, Jürgen, Herstein, Jennifer, Börold, Jacob, Salzburger, Walter, Kaderali, Lars, Briggs, John A.G., Bartenschlager, Ralf
Published in Cell host & microbe

Discovery of highly divergent lineages of plant-associated astro-like viruses sheds light on the emergence of potyviruses

by Lauber, Chris, Seifert, Michael, Bartenschlager, Ralf, Seitz, Stefan
Published in Virus research

Peptide–Boronic Acid Inhibitors of Flaviviral Proteases: Medicinal Chemistry and Structural Biology

by Nitsche, Christoph, Zhang, Linlin, Weigel, Lena F, Schilz, Jonas, Graf, Dominik, Bartenschlager, Ralf, Hilgenfeld, Rolf, Klein, Christian D
Published in Journal of medicinal chemistry

Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies

by Bartenschlager, Ralf, Baumert, Thomas F., Bukh, Jens, Houghton, Michael, Lemon, Stanley M., Lindenbach, Brett D., Lohmann, Volker, Moradpour, Darius, Pietschmann, Thomas, Rice, Charles M., Thimme, Robert, Wakita, Takaji
Published in Virus research

Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation

by Tabata, Keisuke, Prasad, Vibhu, Paul, David, Lee, Ji-Young, Pham, Minh-Tu, Twu, Woan-Ing, Neufeldt, Christopher J, Cortese, Mirko, Cerikan, Berati, Stahl, Yannick, Joecks, Sebastian, Tran, Cong Si, Lüchtenborg, Christian, V'kovski, Philip, Hörmann, Katrin, Müller, André C, Zitzmann, Carolin, Haselmann, Uta, Beneke, Jürgen, Kaderali, Lars, Erfle, Holger, Thiel, Volker, Lohmann, Volker, Superti-Furga, Giulio, Brügger, Britta, Bartenschlager, Ralf
Published in Nature communications

Contribution of autophagy machinery factors to HCV and SARS-CoV-2 replication organelle formation

by Twu, Woan-Ing, Lee, Ji-Young, Kim, Heeyoung, Prasad, Vibhu, Cerikan, Berati, Haselmann, Uta, Tabata, Keisuke, Bartenschlager, Ralf
Published in Cell reports (Cambridge)

Coordination of Hepatitis C Virus Assembly by Distinct Regulatory Regions in Nonstructural Protein 5A

by Zayas, Margarita, Long, Gang, Madan, Vanesa, Bartenschlager, Ralf
Published in PLoS pathogens

Phospholipid synthesis fueled by lipid droplets drives the structural development of poliovirus replication organelles

by Viktorova, Ekaterina G, Nchoutmboube, Jules A, Ford-Siltz, Lauren A, Iverson, Ethan, Belov, George A
Published in PLoS pathogens

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

by Bartenschlager, Ralf, Tschopp, Jürg, Meylan, Etienne, Hofmann, Kay, Moradpour, Darius, Binder, Marco, Curran, Joseph
Published in Nature

Composition and three-dimensional architecture of the dengue virus replication and assembly sites

by Welsch, Sonja, Miller, Sven, Romero-Brey, Ines, Merz, Andreas, Bleck, Christopher K E, Walther, Paul, Fuller, Stephen D, Antony, Claude, Krijnse-Locker, Jacomine, Bartenschlager, Ralf
Published in Cell host & microbe

Structural and Functional Properties of the Hepatitis C Virus p7 Viroporin

by Madan, Vanesa, Bartenschlager, Ralf
Published in Viruses

A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replicat...

by Płaszczyca, Anna, Scaturro, Pietro, Neufeldt, Christopher John, Cortese, Mirko, Cerikan, Berati, Ferla, Salvatore, Brancale, Andrea, Pichlmair, Andreas, Bartenschlager, Ralf
Published in PLoS pathogens

Subcellular Localization and Membrane Topology of the Dengue Virus Type 2 Non-structural Protein 4B

by Miller, Sven, Sparacio, Sandra, Bartenschlager, Ralf
Published in The Journal of biological chemistry

Quantitative Analysis of the Hepatitis C Virus Replication Complex

by QUINKERT, Doris, BARTENSCHLAGER, Ralf, LOHMANN, Volker
Published in Journal of Virology

SARS-CoV-2 nsp3 and nsp4 are minimal constituents of a pore spanning replication organelle

by Zimmermann, Liv, Zhao, Xiaohan, Makroczyova, Jana, Wachsmuth-Melm, Moritz, Prasad, Vibhu, Hensel, Zach, Bartenschlager, Ralf, Chlanda, Petr
Published in Nature communications