Imbalance in the response of pre- and post-synaptic components to amyloidopathy

by Stephen, Terri-Leigh, Tamagnini, Francesco, Piegsa, Judith, Sung, Katherine, Harvey, Joshua, Oliver-Evans, Alice, Murray, Tracey K, Ahmed, Zeshan, Hutton, Michael L, Randall, Andrew, O'Neill, Michael J, Jackson, Johanna S
Published in Scientific reports

Epidemic spreading model to characterize misfolded proteins propagation in aging and associated neurodegenerative disorders

by Iturria-Medina, Yasser, Sotero, Roberto C, Toussaint, Paule J, Evans, Alan C
Published in PLoS computational biology

CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology

by Bradshaw, Elizabeth M, Chibnik, Lori B, Keenan, Brendan T, Ottoboni, Linda, Raj, Towfique, Tang, Anna, Rosenkrantz, Laura L, Imboywa, Selina, Lee, Michelle, Von Korff, Alina, Morris, Martha C, Evans, Denis A, Johnson, Keith, Sperling, Reisa A, Schneider, Julie A, Bennett, David A, De Jager, Philip L
Published in Nature neuroscience

Spread of pathological tau proteins through communicating neurons in human Alzheimer's disease

by Vogel, Jacob W, Iturria-Medina, Yasser, Strandberg, Olof T, Smith, Ruben, Levitis, Elizabeth, Evans, Alan C, Hansson, Oskar
Published in Nature communications

PP140 Burden of Illness And Health Care Costs In People with Alzheimer’s Disease

by Edwards, Sophie, Hahn-Pedersen, Julie, Robinson, Danielle, Chan, Mei Sum, Bray, Benjamin, Clark, Alice, Ivkovic, Milana, Michalak, Wojciech, Wichmann, Christian, Berry, Sasha, Evans, Marc
Published in International journal of technology assessment in health care

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

by Escott-Price, Valentina, Harold, Denise, Jones, Lesley, Gerrish, Amy, Vedernikov, Alexey, DeStefano, Anita L, Ibrahim-Verbaas, Carla A, Bis, Joshua C, Grenier-Boley, Benjamin, Russo, Giancarlo, Smith, Albert V, Chouraki, Vincent, Thomas, Charlene, Zelenika, Diana, Kamatani, Yoichiro, Lin, Chiao-Feng, Dunstan, Melanie L, Vronskaya, Maria, Ruiz, Agustin, Bihoreau, Marie-Thérèse, Reitz, Christiane, Pasquier, Florence, Hollingworth, Paul, Hanon, Olivier, Fitzpatrick, Annette L, Becker, Tim, Gudnason, Vilmundur, Amin, Najaf, De Jager, Philip L, Johnston, Janet A, Evans, Denis, Hernández, Isabel, Goate, Alison M, Fiévet, Nathalie, Kamboh, M Ilyas, Keller, Lina, McGuinness, Bernadette, Wallon, David, Love, Seth, Gallacher, John, George-Hyslop, Peter St, Lleo, Alberto, Bayer, Anthony, Tsuang, Debby W, Yu, Lei, Spalletta, Gianfranco, Proitsi, Petra, Sorbi, Sandro, Garcia, Florentino Sanchez, Fox, Nick C, Naranjo, Maria Candida Deniz, Bosco, Paolo, Clarke, Robert, Brayne, Carol, Bonuccelli, Ubaldo, Mancuso, Michelangelo, Moebus, Susanne, Zompo, Maria Del, Maier, Wolfgang, Panza, Francesco, Caffarra, Paolo, Perry, William, Mayhaus, Manuel, Lannfelt, Lars, Pichler, Sabrina, Carrasquillo, Minerva M, Alvarez, Victoria, Valladares, Otto, Hamilton-Nelson, Kara L, Pastor, Pau, Owen, Michael J, Faber, Kelley M, Jonsson, Palmi V, O'Donovan, Michael C, Cantwell, Laura B, Blacker, Deborah, Mead, Simon, Mosley, Jr, Thomas H, de Bruijn, Renee F A G, Passmore, Peter, Brice, Alexis, Morgan, Kevin, Foroud, Tatiana M, Kukull, Walter A, Hannequin, Didier, Powell, John F, Nalls, Michael A, Ritchie, Karen, Kauwe, John S K, Riemenschneider, Matthias, Boada, Mercè, Martin, Eden R, Rujescu, Dan, Tzourio, Christophe, Hofman, Albert, Graff, Caroline, Launer, Lenore J, Van Broeckhoven, Christine, van Duijn, Cornelia M, Seshadri, Sudha
Published in PloS one

Random forest-based similarity measures for multi-modal classification of Alzheimer's disease

by Gray, Katherine R., Aljabar, Paul, Heckemann, Rolf A., Hammers, Alexander, Rueckert, Daniel
Published in NeuroImage (Orlando, Fla.)

Non-coding variability at the APOE locus contributes to the Alzheimer's risk

by Zhou, Xiaopu, Chen, Yu, Mok, Kin Y, Kwok, Timothy C Y, Mok, Vincent C T, Guo, Qihao, Ip, Fanny C, Chen, Yuewen, Mullapudi, Nandita, Giusti-Rodríguez, Paola, Sullivan, Patrick F, Hardy, John, Fu, Amy K Y, Li, Yun, Ip, Nancy Y
Published in Nature communications

The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory

by Franzmeier, Nicolai, Rubinski, Anna, Neitzel, Julia, Ewers, Michael
Published in Nature communications

Multi-method analysis of MRI images in early diagnostics of Alzheimer's disease

by Wolz, Robin, Julkunen, Valtteri, Koikkalainen, Juha, Niskanen, Eini, Zhang, Dong Ping, Rueckert, Daniel, Soininen, Hilkka, Lötjönen, Jyrki
Published in PloS one

Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort

by Shen, Li, Kim, Sungeun, Risacher, Shannon L., Nho, Kwangsik, Swaminathan, Shanker, West, John D., Foroud, Tatiana, Pankratz, Nathan, Moore, Jason H., Sloan, Chantel D., Huentelman, Matthew J., Craig, David W., DeChairo, Bryan M., Potkin, Steven G., Jack, Clifford R., Weiner, Michael W., Saykin, Andrew J.
Published in NeuroImage (Orlando, Fla.)

Development and assessment of a composite score for memory in the Alzheimer’s Disease Neuroimaging Initiative (ADNI)

by Crane, Paul K., Carle, Adam, Gibbons, Laura E., Insel, Philip, Mackin, R. Scott, Gross, Alden, Jones, Richard N., Mukherjee, Shubhabrata, Curtis, S. McKay, Harvey, Danielle, Weiner, Michael, Mungas, Dan
Published in Brain imaging and behavior

Multi-source feature learning for joint analysis of incomplete multiple heterogeneous neuroimaging data

by Yuan, Lei, Wang, Yalin, Thompson, Paul M., Narayan, Vaibhav A., Ye, Jieping
Published in NeuroImage (Orlando, Fla.)

A composite score for executive functioning, validated in Alzheimer’s Disease Neuroimaging Initiative (ADNI) participants with baseline mild cognitive impairment

by Gibbons, Laura E., Carle, Adam C., Mackin, R. Scott, Harvey, Danielle, Mukherjee, Shubhabrata, Insel, Philip, Curtis, S. McKay, Mungas, Dan, Crane, Paul K.
Published in Brain imaging and behavior

Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity

by Jahanshad, Neda, Rajagopalan, Priya, Hua, Xue, Hibar, Derrek P., Nir, Talia M., Toga, Arthur W., Jack, Clifford R., Saykin, Andrew J., Green, Robert C., Weiner, Michael W., Medland, Sarah E., Montgomery, Grant W., Hansell, Narelle K., McMahon, Katie L., de Zubicaray, Greig I., Martin, Nicholas G., Wright, Margaret J., Thompson, Paul M.
Published in Proceedings of the National Academy of Sciences - PNAS

Robust Identification of Alzheimer's Disease subtypes based on cortical atrophy patterns

by Park, Jong-Yun, Na, Han Kyu, Kim, Sungsoo, Kim, Hyunwook, Kim, Hee Jin, Seo, Sang Won, Na, Duk L, Han, Cheol E, Seong, Joon-Kyung
Published in Scientific reports

Standardization of analysis sets for reporting results from ADNI MRI data

by Wyman, Bradley T, Harvey, Danielle J, Crawford, Karen, Bernstein, Matt A, Carmichael, Owen, Cole, Patricia E, Crane, Paul K, DeCarli, Charles, Fox, Nick C, Gunter, Jeffrey L, Hill, Derek, Killiany, Ronald J, Pachai, Chahin, Schwarz, Adam J, Schuff, Norbert, Senjem, Matthew L, Suhy, Joyce, Thompson, Paul M, Weiner, Michael, Jack, Clifford R
Published in Alzheimer's & dementia

Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H2O2- and Aβ1-42-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells

by de Matos, Ana M., Martins, Alice, Man, Teresa, Evans, David, Walter, Magnus, Oliveira, Maria Conceição, López, Óscar, Fernandez-Bolaños, José G., Dätwyler, Philipp, Ernst, Beat, Macedo, M. Paula, Contino, Marialessandra, Colabufo, Nicola A., Rauter, Amélia P.
Published in Pharmaceuticals (Basel, Switzerland)

Subregional neuroanatomical change as a biomarker for Alzheimer's disease

by Holland, Dominic, Fenema-Notestine, Christine, Weiner, Michael, Thal, Leon, Petersen, Ronald, Jagust, William, Toga, Arthur W, Green, Robert C, Potter, William Z, Montine, Tom, Bernstein, Matthew, Felmlee, Joel, Fox, Nick, Thompson, Paul, Schuff, Norbert, Foster, Norm, Chen, Kewei, Lee, Virginia M.-Y, Crawford, Karen, Neu, Scott, Snyder, Peter J, Kaye, Jeffrey, Vorobik, Remi, Quinn, Joseph, Spann, Bryan, Fleisher, Adam S, Heidebrink, Judith L, Doody, Rachelle S, Villanueva-Meyer, Javier, Chowdhury, Munir, Bell, Karen L, Mintun, Mark A, Schneider, Stacy, Marson, Daniel, Griffith, Randall, Badger, Beverly, Stern, Jessica, Bach, Julie, Duara, Ranjan, Isaacson, Richard, Albert, Marilyn S, Toroney, Jaimie, de Leon, Mony J, Petrella, Jeffrey R, Clark, Christopher M, Nunez, Jessica, Smith, Charles D, Given, Curtis A. II, Hardy, Peter, DeKosky, Steven T, Oakley, MaryAnn, Ismail, M. Saleem, McCallum, Colleen, McAdams-Ortiz, Catherine, Martin-Cook, Kristen, Levey, Allan I, Lah, James J, Cellar, Janet S, Burns, Jeffrey M, Laubinger, Mary M, Silverman, Daniel H.S, Lu, Po H, Johnson, Heather, Farlow, Martin, Herring, Scott, MacAvoy, Martha G, Bifano, Laurel A, Bergman, Howard, Hosein, Chris, Caldwell, Curtis, Assaly, Michele, Rogers, John, Sadowsky, Carl, Villena, Teresa, Mesner, Scott, Aisen, Paul S, Johnson, Kathleen B, Johnson, Keith A, Rosen, Allyson, Connor, Donald, Obradov, Sanja, Killiany, Ron, Jayam-Trouth, Annapurni, Wang, Paul, DeCarli, Charles, Kittur, Smita, Johnson, Sterling C, Borrie, Michael, Lee, T.-Y, Highum, Diane, Hendin, Barry A, Kataki, Maria, Anderson, Karen, Saykin, Andrew J, Williamson, Jeff D, Potter, Huntington, Ashok Raj, B, Ott, Brian R, Cohen, Ronald, Wilks, Kerri L
Published in Proceedings of the National Academy of Sciences - PNAS

Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration

by Franzmeier, Nicolai, Suárez-Calvet, M, Frontzkowski, Lukas, Moore, Annah, Hohman, Timothy J, Morenas-Rodriguez, Estrella, Nuscher, Brigitte, Shaw, Leslie, Trojanowski, John Q, Dichgans, Martin, Kleinberger, Gernot, Haass, Christian, Ewers, Michael
Published in Molecular neurodegeneration